Noteworthy changes in release 1.2.1 (3 February 2015) * Reinstated hts_file_type() and FT_* macros, which were available until 1.1 but briefly removed in 1.2. This function is deprecated and will be removed in a future release -- you should use hts_detect_format() etc instead Noteworthy changes in release 1.2 (2 February 2015) * HTSlib now has a configure script which checks your build environment and allows for selection of optional extras. See INSTALL for details * By default, reference sequences are fetched from the EBI CRAM Reference Registry and cached in your $HOME cache directory. This behaviour can be controlled by setting REF_PATH and REF_CACHE enviroment variables (see the samtools(1) man page for details) * Numerous CRAM improvements: - Support for CRAM v3.0, an upcoming revision to CRAM supporting better compression and per-container checksums - EOF checking for v2.1 and v3.0 (similar to checking BAM EOF blocks) - Non-standard values for PNEXT and TLEN fields are now preserved - hts_set_fai_filename() now provides a reference file when encoding - Generated read names are now numbered from 1, rather than being labelled 'slice:record-in-slice' - Multi-threading and speed improvements * New htsfile command for identifying file formats, and corresponding file format detection APIs * New tabix --regions FILE, --targets FILE options for filtering via BED files * Optional iRODS file access, disabled by default. Configure with --with-irods to enable accessing iRODS data objects directly via 'irods:DATAOBJ' * All occurences of 2^29 in the source have been eliminated, so indexing and querying against reference sequences larger than 512Mbp works (when using CSI indices) * Support for plain GZIP compression in various places * VCF header editing speed improvements * Added seq_nt16_int[] (equivalent to the samtools API's bam_nt16_nt4_table) * Reinstated faidx_fetch_nseq(), which was accidentally removed from 1.1. Now faidx_fetch_nseq() and faidx_nseq() are equivalent; eventually faidx_fetch_nseq() will be deprecated and removed [#156] * Fixed bugs #141, #152, #155, #158, #159, and various memory leaks