# go_term

go_id: GO:0031478
term: myosin VIII complex
ontology: CC
definition:
A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain.


go_id: GO:0031479
term: myosin IX complex
ontology: CC
definition:
A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins.


go_id: GO:0031481
term: myosin XI complex
ontology: CC
definition:
A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions.


go_id: GO:0031482
term: myosin XII complex
ontology: CC
definition:
A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil.


go_id: GO:0031484
term: myosin XIV complex
ontology: CC
definition:
A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.


go_id: GO:0031485
term: myosin XV complex
ontology: CC
definition:
A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII.


go_id: GO:0031486
term: myosin XVI complex
ontology: CC
definition:
A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat.


go_id: GO:0031488
term: myosin XVIII complex
ontology: CC
definition:
A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain.


go_id: GO:0031489
term: myosin V binding
ontology: MF
definition:
Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.


go_id: GO:0031491
term: nucleosome binding
ontology: MF
definition:
Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.


go_id: GO:0031494
term: regulation of mating type switching
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.


go_id: GO:0031495
term: negative regulation of mating type switching
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching.


go_id: GO:0031498
term: chromatin disassembly
ontology: BP
definition:
The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA.


go_id: GO:0031499
term: TRAMP complex
ontology: CC
definition:
A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.


go_id: GO:0031500
term: Tea1 cell-end complex
ontology: CC
definition:
A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.


go_id: GO:0031502
term: dolichyl-phosphate-mannose-protein mannosyltransferase complex
ontology: CC
definition:
A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies.


go_id: GO:0031503
term: protein complex localization
ontology: BP
definition:
A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.


go_id: GO:0031504
term: peptidoglycan-based cell wall organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall.


go_id: GO:0031505
term: fungal-type cell wall organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.


go_id: GO:0031506
term: cell wall glycoprotein biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues.


go_id: GO:0031507
term: heterochromatin assembly
ontology: BP
definition:
The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent.


go_id: GO:0031508
term: pericentric heterochromatin assembly
ontology: BP
definition:
The assembly of chromatin into heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.


go_id: GO:0031511
term: Mis6-Sim4 complex
ontology: CC
definition:
A protein complex that forms part of the inner centromere, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.


go_id: GO:0031512
term: motile primary cilium
ontology: CC
definition:
A primary cilium which may contain a variable array of axonemal microtubules and also contains molecular motors. Motile primary cilia display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization.


go_id: GO:0031513
term: nonmotile primary cilium
ontology: CC
definition:
A primary cilium which contains a variable array of axonemal microtubules but does not contain molecular motors. Nonmotile primary cilia are found on many different cell types and function as sensory organelles that concentrate and organize sensory signaling molecules.


go_id: GO:0031514
term: motile cilium
ontology: CC
definition:
A cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface. Motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues. Motile cilia may also function as sensory organelles.


go_id: GO:0031515
term: tRNA (m1A) methyltransferase complex
ontology: CC
definition:
A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer.


go_id: GO:0031516
term: far-red light photoreceptor activity
ontology: MF
definition:
The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation.


go_id: GO:0031517
term: red light photoreceptor activity
ontology: MF
definition:
The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.


go_id: GO:0031518
term: CBF3 complex
ontology: CC
definition:
A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p.


go_id: GO:0031519
term: PcG protein complex
ontology: CC
definition:
A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.


go_id: GO:0031521
term: spitzenkorper
ontology: CC
definition:
Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.


go_id: GO:0031522
term: cell envelope Sec protein transport complex
ontology: CC
definition:
A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.


go_id: GO:0031523
term: Myb complex
ontology: CC
definition:
A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression.


go_id: GO:0031524
term: menthol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.


go_id: GO:0031525
term: menthol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.


go_id: GO:0031529
term: ruffle organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.


go_id: GO:0031530
term: gonadotropin-releasing hormone receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.


go_id: GO:0031531
term: thyrotropin-releasing hormone receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary.


go_id: GO:0031532
term: actin cytoskeleton reorganization
ontology: BP
definition:
A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.


go_id: GO:0031533
term: mRNA cap methyltransferase complex
ontology: CC
definition:
A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.


go_id: GO:0031534
term: minus-end directed microtubule sliding
ontology: BP
definition:
The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.


go_id: GO:0031535
term: plus-end directed microtubule sliding
ontology: BP
definition:
The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules.


go_id: GO:0031536
term: positive regulation of exit from mitosis
ontology: BP
definition:
Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).


go_id: GO:0031537
term: regulation of anthocyanin metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.


go_id: GO:0031538
term: negative regulation of anthocyanin metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.


go_id: GO:0031539
term: positive regulation of anthocyanin metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.


go_id: GO:0031540
term: regulation of anthocyanin biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.


go_id: GO:0031541
term: negative regulation of anthocyanin biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.


go_id: GO:0031542
term: positive regulation of anthocyanin biosynthetic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.


go_id: GO:0031543
term: peptidyl-proline dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2.


go_id: GO:0031544
term: peptidyl-proline 3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.


go_id: GO:0031545
term: peptidyl-proline 4-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2.


go_id: GO:0031547
term: brain-derived neurotrophic factor receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.


go_id: GO:0031548
term: regulation of brain-derived neurotrophic factor receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.


go_id: GO:0031549
term: negative regulation of brain-derived neurotrophic factor receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.


go_id: GO:0031550
term: positive regulation of brain-derived neurotrophic factor receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.


go_id: GO:0031551
term: regulation of brain-derived neurotrophic factor-activated receptor activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.


go_id: GO:0031552
term: negative regulation of brain-derived neurotrophic factor-activated receptor activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.


go_id: GO:0031553
term: positive regulation of brain-derived neurotrophic factor-activated receptor activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.


go_id: GO:0031554
term: regulation of DNA-templated transcription, termination
ontology: BP
definition:
Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.


go_id: GO:0031556
term: transcriptional attenuation by ribosome
ontology: BP
definition:
A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.


go_id: GO:0031560
term: cellular bud neck polarisome
ontology: CC
definition:
Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.


go_id: GO:0031561
term: cellular bud tip polarisome
ontology: CC
definition:
Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.


go_id: GO:0031562
term: hyphal tip polarisome
ontology: CC
definition:
Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.


go_id: GO:0031563
term: mating projection tip polarisome
ontology: CC
definition:
Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone.


go_id: GO:0031564
term: transcription antitermination
ontology: BP
definition:
Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond a termination site.


go_id: GO:0031566
term: actomyosin contractile ring maintenance
ontology: BP
definition:
The cell cycle process in which the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures. This process occurs in the context of cytokinesis that takes place as part of a cell cycle.


go_id: GO:0031567
term: mitotic cell size control checkpoint
ontology: BP
definition:
The mitotic cell cycle checkpoint that delays or arrests cell cycle progression until cells have reached a critical size.


go_id: GO:0031568
term: G1 cell size control checkpoint
ontology: BP
definition:
A mitotic cell cycle checkpoint that monitors cell size, and negatively regulates cell cycle progression between G1 and S phase until a critical size is reached.


go_id: GO:0031569
term: G2 cell size control checkpoint
ontology: BP
definition:
A cell cycle checkpoint that monitors cell size, and negatively regulates cell cycle progression between G2 and M phase until a critical size is reached.


go_id: GO:0031570
term: DNA integrity checkpoint
ontology: BP
definition:
A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.


go_id: GO:0031571
term: mitotic G1 DNA damage checkpoint
ontology: BP
definition:
A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G1/S transition of the cell cycle in response to DNA damage.


go_id: GO:0031572
term: G2 DNA damage checkpoint
ontology: BP
definition:
A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the cell cycle in response to DNA damage.


go_id: GO:0031573
term: intra-S DNA damage checkpoint
ontology: BP
definition:
A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression.


go_id: GO:0031578
term: mitotic spindle orientation checkpoint
ontology: BP
definition:
A cell cycle checkpoint that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected.


go_id: GO:0031579
term: membrane raft organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


go_id: GO:0031581
term: hemidesmosome assembly
ontology: BP
definition:
Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.


go_id: GO:0031582
term: replication fork arrest at rDNA repeats
ontology: BP
definition:
A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.


go_id: GO:0031583
term: phospholipase D-activating G-protein coupled receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase D (PLD) and a subsequent increase in cellular levels of phosphatidic acid (PA).


go_id: GO:0031585
term: regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


go_id: GO:0031586
term: negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


go_id: GO:0031587
term: positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


go_id: GO:0031590
term: wybutosine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.


go_id: GO:0031591
term: wybutosine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.


go_id: GO:0031592
term: centrosomal corona
ontology: CC
definition:
An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin.


go_id: GO:0031594
term: neuromuscular junction
ontology: CC
definition:
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.


go_id: GO:0031600
term: cytosolic proteasome regulatory particle
ontology: CC
definition:
A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex.


go_id: GO:0031604
term: nuclear proteasome core complex, alpha-subunit complex
ontology: CC
definition:
The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell.


go_id: GO:0031606
term: cytosolic proteasome core complex, alpha-subunit complex
ontology: CC
definition:
The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex.


go_id: GO:0031607
term: nuclear proteasome core complex, beta-subunit complex
ontology: CC
definition:
The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell.


go_id: GO:0031609
term: cytosolic proteasome core complex, beta-subunit complex
ontology: CC
definition:
The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex.


go_id: GO:0031610
term: nuclear proteasome regulatory particle, base subcomplex
ontology: CC
definition:
The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell.


go_id: GO:0031612
term: cytosolic proteasome regulatory particle, base subcomplex
ontology: CC
definition:
The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell.


go_id: GO:0031613
term: nuclear proteasome regulatory particle, lid subcomplex
ontology: CC
definition:
The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell.


go_id: GO:0031615
term: cytosolic proteasome regulatory particle, lid subcomplex
ontology: CC
definition:
The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.


go_id: GO:0031617
term: NMS complex
ontology: CC
definition:
A supercomplex formed by the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) with additional proteins at the kinetochores of condensed nuclear chromosomes.


go_id: GO:0031618
term: nuclear pericentric heterochromatin
ontology: CC
definition:
Nuclear heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.


go_id: GO:0031619
term: homologous chromosome orientation involved in meiotic metaphase I plate congression
ontology: BP
definition:
The cell cycle process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I.


go_id: GO:0031623
term: receptor internalization
ontology: BP
definition:
A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.


go_id: GO:0031624
term: ubiquitin conjugating enzyme binding
ontology: MF
definition:
Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins.


go_id: GO:0031625
term: ubiquitin protein ligase binding
ontology: MF
definition:
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.


go_id: GO:0031626
term: beta-endorphin binding
ontology: MF
definition:
Interacting selectively and non-covalently with beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin.


go_id: GO:0031627
term: telomeric loop formation
ontology: BP
definition:
The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region.


go_id: GO:0031629
term: synaptic vesicle fusion to presynaptic membrane
ontology: BP
definition:
Fusion of the membrane of a synaptic vesicle with its target presynaptic membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.


go_id: GO:0031630
term: regulation of synaptic vesicle fusion to presynaptic membrane
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.


go_id: GO:0031631
term: negative regulation of synaptic vesicle fusion to presynaptic membrane
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.


go_id: GO:0031632
term: positive regulation of synaptic vesicle fusion to presynaptic membrane
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.


go_id: GO:0031634
term: replication fork barrier binding
ontology: MF
definition:
Interacting selectively and non-covalently with replication fork barriers, sites that inhibit the progress of replication forks.


go_id: GO:0031635
term: adenylate cyclase-inhibiting opioid receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of an opioid receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).


go_id: GO:0031637
term: regulation of neuronal synaptic plasticity in response to neurotrophin
ontology: BP
definition:
The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.


go_id: GO:0031639
term: plasminogen activation
ontology: BP
definition:
The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.


go_id: GO:0031640
term: killing of cells of other organism
ontology: BP
definition:
Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.


go_id: GO:0031641
term: regulation of myelination
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.


go_id: GO:0031642
term: negative regulation of myelination
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.


go_id: GO:0031643
term: positive regulation of myelination
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons.


go_id: GO:0031644
term: regulation of neurological system process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.


go_id: GO:0031645
term: negative regulation of neurological system process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.


go_id: GO:0031646
term: positive regulation of neurological system process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of a neurophysiological process.


go_id: GO:0031647
term: regulation of protein stability
ontology: BP
definition:
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.


go_id: GO:0031648
term: protein destabilization
ontology: BP
definition:
Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.


go_id: GO:0031649
term: heat generation
ontology: BP
definition:
Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.


go_id: GO:0031653
term: heat dissipation
ontology: BP
definition:
Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.


go_id: GO:0031657
ontology: BP
term:
regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

definition:
Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.


go_id: GO:0031658
ontology: BP
term:
negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.


go_id: GO:0031659
ontology: BP
term:
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle

definition:
Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.


go_id: GO:0031660
ontology: BP
term:
regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle

definition:
Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.


go_id: GO:0031661
ontology: BP
term:
negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle

definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.


go_id: GO:0031662
ontology: BP
term:
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle

definition:
Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity involved in the G2/M transition of the cell cycle.


go_id: GO:0031663
term: lipopolysaccharide-mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.


go_id: GO:0031664
term: regulation of lipopolysaccharide-mediated signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.


go_id: GO:0031665
term: negative regulation of lipopolysaccharide-mediated signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.


go_id: GO:0031666
term: positive regulation of lipopolysaccharide-mediated signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.


go_id: GO:0031667
term: response to nutrient levels
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.


go_id: GO:0031668
term: cellular response to extracellular stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.


go_id: GO:0031669
term: cellular response to nutrient levels
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.


go_id: GO:0031670
term: cellular response to nutrient
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.


go_id: GO:0031671
term: primary cell septum biogenesis
ontology: BP
definition:
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division.


go_id: GO:0031672
term: A band
ontology: CC
definition:
The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.


go_id: GO:0031673
term: H zone
ontology: CC
definition:
A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments.


go_id: GO:0031674
term: I band
ontology: CC
definition:
A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.


go_id: GO:0031680
term: G-protein beta/gamma-subunit complex
ontology: CC
definition:
The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.


go_id: GO:0031684
term: heterotrimeric G-protein complex cycle
ontology: BP
definition:
The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits.


go_id: GO:0031720
term: haptoglobin binding
ontology: MF
definition:
Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.


go_id: GO:0031753
term: endothelial differentiation G-protein coupled receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with an endothelial differentiation G-protein coupled receptor.


go_id: GO:0031806
term: G-protein coupled histamine receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a G-protein coupled (metabotropic) histamine receptor.


go_id: GO:0031811
term: G-protein coupled nucleotide receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a G-protein coupled (metabotropic) nucleotide receptor.


go_id: GO:0031848
term: protection from non-homologous end joining at telomere
ontology: BP
definition:
A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse.


go_id: GO:0031858
term: pituitary adenylate cyclase-activating polypeptide receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a pituitary adenylate cyclase-activating polypeptide receptor.


go_id: GO:0031860
term: telomeric 3' overhang formation
ontology: BP
definition:
The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans.


go_id: GO:0031891
term: type 1 vasoactive intestinal polypeptide receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a type 1 vasoactive intestinal polypeptide receptor.


go_id: GO:0031892
term: type 2 vasoactive intestinal polypeptide receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a type 2 vasoactive intestinal polypeptide receptor.


go_id: GO:0031897
term: Tic complex
ontology: CC
definition:
The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane.


go_id: GO:0031898
term: chromoplast envelope
ontology: CC
definition:
The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.


go_id: GO:0031899
term: chromoplast inner membrane
ontology: CC
definition:
The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma.


go_id: GO:0031912
term: oral apparatus
ontology: CC
definition:
Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems.


go_id: GO:0031913
term: contractile vacuole pore
ontology: CC
definition:
Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium.


go_id: GO:0031914
term: negative regulation of synaptic plasticity
ontology: BP
definition:
A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.


go_id: GO:0031915
term: positive regulation of synaptic plasticity
ontology: BP
definition:
A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.


go_id: GO:0031916
term: regulation of synaptic metaplasticity
ontology: BP
definition:
A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.


go_id: GO:0031917
term: negative regulation of synaptic metaplasticity
ontology: BP
definition:
A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.


go_id: GO:0031918
term: positive regulation of synaptic metaplasticity
ontology: BP
definition:
A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.


go_id: GO:0031919
term: vitamin B6 transport
ontology: BP
definition:
The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0031920
term: pyridoxal transport
ontology: BP
definition:
The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


go_id: GO:0031921
term: pyridoxal phosphate transport
ontology: BP
definition:
The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.


go_id: GO:0031922
term: pyridoxamine transport
ontology: BP
definition:
The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


go_id: GO:0031923
term: pyridoxine transport
ontology: BP
definition:
The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


go_id: GO:0031924
term: vitamin B6 transporter activity
ontology: MF
definition:
Enables the directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells.


go_id: GO:0031925
term: pyridoxal transmembrane transporter activity
ontology: MF
definition:
Enables the directed movement of pyridoxal across a membrane into, out of or within a cell, or between cells. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


go_id: GO:0031926
term: pyridoxal phosphate transmembrane transporter activity
ontology: MF
definition:
Enables the directed movement of pyridoxal phosphate into, out of or within a cell, or between cells; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.


go_id: GO:0031927
term: pyridoxamine transmembrane transporter activity
ontology: MF
definition:
Enables the directed movement of pyridoxamine into, out of or within a cell, or between cells. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


go_id: GO:0031928
term: pyridoxine transmembrane transporter activity
ontology: MF
definition:
Enables the directed movement of pyridoxine across a membrane into, out of or within a cell, or between cells. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.


go_id: GO:0031929
term: TOR signaling
ontology: BP
definition:
A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.


go_id: GO:0031930
term: mitochondria-nucleus signaling pathway
ontology: BP
definition:
A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function.


go_id: GO:0031931
term: TORC1 complex
ontology: CC
definition:
A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p.


go_id: GO:0031932
term: TORC2 complex
ontology: CC
definition:
A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.


go_id: GO:0031939
term: negative regulation of chromatin silencing at telomere
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres.


go_id: GO:0031940
term: positive regulation of chromatin silencing at telomere
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of chromatin silencing at telomeres.


go_id: GO:0031942
term: i-AAA complex
ontology: CC
definition:
Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases.


go_id: GO:0031943
term: regulation of glucocorticoid metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.


go_id: GO:0031944
term: negative regulation of glucocorticoid metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.


go_id: GO:0031945
term: positive regulation of glucocorticoid metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.


go_id: GO:0031946
term: regulation of glucocorticoid biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.


go_id: GO:0031947
term: negative regulation of glucocorticoid biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.


go_id: GO:0031948
term: positive regulation of glucocorticoid biosynthetic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.


go_id: GO:0031949
term: regulation of glucocorticoid catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.


go_id: GO:0031950
term: negative regulation of glucocorticoid catabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.


go_id: GO:0031951
term: positive regulation of glucocorticoid catabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.


go_id: GO:0031952
term: regulation of protein autophosphorylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues.


go_id: GO:0031953
term: negative regulation of protein autophosphorylation
ontology: BP
definition:
Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.


go_id: GO:0031954
term: positive regulation of protein autophosphorylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.


go_id: GO:0031955
term: short-chain fatty acid-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + a short-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; short-chain fatty acids are fatty acids with a chain length of less than C6.


go_id: GO:0031956
term: medium-chain fatty acid-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a medium-chain fatty acid is any fatty acid with a chain length of between C6 and C12.


go_id: GO:0031957
term: very long-chain fatty acid-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + a very-long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22.


go_id: GO:0031958
term: corticosteroid receptor signaling pathway
ontology: BP
definition:
Any series of molecular signals generated as a consequence of a corticosteroid binding to its receptor.


go_id: GO:0031959
term: mineralocorticoid receptor signaling pathway
ontology: BP
definition:
Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor.


go_id: GO:0031960
term: response to corticosteroid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.


go_id: GO:0031963
term: cortisol receptor activity
ontology: MF
definition:
Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function.


go_id: GO:0031965
term: nuclear membrane
ontology: CC
definition:
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.


go_id: GO:0031967
term: organelle envelope
ontology: CC
definition:
A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.


go_id: GO:0031974
term: membrane-enclosed lumen
ontology: CC
definition:
The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.


go_id: GO:0031975
term: envelope
ontology: CC
definition:
A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.


go_id: GO:0031985
term: Golgi cisterna
ontology: CC
definition:
Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.


go_id: GO:0031987
term: locomotion involved in locomotory behavior
ontology: BP
definition:
Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.


go_id: GO:0031989
term: bombesin receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of a bombesin receptor binding to one of its physiological ligands.


go_id: GO:0031990
term: mRNA export from nucleus in response to heat stress
ontology: BP
definition:
The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export.


go_id: GO:0031991
term: regulation of actomyosin contractile ring contraction
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle.


go_id: GO:0031992
term: energy transducer activity
ontology: MF
definition:
The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell.


go_id: GO:0031993
term: light transducer activity
ontology: MF
definition:
Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell.


go_id: GO:0031997
term: N-terminal myristoylation domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin.


go_id: GO:0031999
term: negative regulation of fatty acid beta-oxidation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.


go_id: GO:0032001
term: 1,4-alpha-glucan 6-alpha-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan.


go_id: GO:0032002
term: interleukin-28 receptor complex
ontology: CC
definition:
A protein complex that binds interleukin-28 and interleukin-29. Composed of two subunits, IL-28R alpha and IL-10R beta.


go_id: GO:0032005
term: signal transduction involved in conjugation with cellular fusion
ontology: BP
definition:
The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.


go_id: GO:0032009
term: early phagosome
ontology: CC
definition:
A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.


go_id: GO:0032010
term: phagolysosome
ontology: CC
definition:
A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes.


go_id: GO:0032011
term: ARF protein signal transduction
ontology: BP
definition:
A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state.


go_id: GO:0032013
term: negative regulation of ARF protein signal transduction
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction.


go_id: GO:0032014
term: positive regulation of ARF protein signal transduction
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction.


go_id: GO:0032016
term: negative regulation of Ran protein signal transduction
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction.


go_id: GO:0032017
term: positive regulation of Ran protein signal transduction
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction.


go_id: GO:0032019
term: mitochondrial cloud
ontology: CC
definition:
A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.


go_id: GO:0032021
term: NELF complex
ontology: CC
definition:
A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing.


go_id: GO:0032022
term: multicellular pellicle formation
ontology: BP
definition:
A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface.


go_id: GO:0032024
term: positive regulation of insulin secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.


go_id: GO:0032025
term: response to cobalt ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.


go_id: GO:0032026
term: response to magnesium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.


go_id: GO:0032039
term: integrator complex
ontology: CC
definition:
A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.


go_id: GO:0032040
term: small-subunit processome
ontology: CC
definition:
A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.


go_id: GO:0032041
term: NAD-dependent histone deacetylase activity (H3-K14 specific)
ontology: MF
definition:
Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.


go_id: GO:0032044
term: DSIF complex
ontology: CC
definition:
A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes.


go_id: GO:0032046
term: micropexophagy-specific membrane apparatus
ontology: CC
definition:
A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole.


go_id: GO:0032047
term: mitosome
ontology: CC
definition:
A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria.


go_id: GO:0032049
term: cardiolipin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.


go_id: GO:0032052
term: bile acid binding
ontology: MF
definition:
Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile.


go_id: GO:0032053
term: ciliary basal body organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).


go_id: GO:0032055
term: negative regulation of translation in response to stress
ontology: BP
definition:
Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress.


go_id: GO:0032056
term: positive regulation of translation in response to stress
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress.


go_id: GO:0032057
term: negative regulation of translational initiation in response to stress
ontology: BP
definition:
Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.


go_id: GO:0032058
term: positive regulation of translational initiation in response to stress
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress.


go_id: GO:0032059
term: bleb
ontology: CC
definition:
A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.


go_id: GO:0032060
term: bleb assembly
ontology: BP
definition:
The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.


go_id: GO:0032061
term: negative regulation of translation in response to osmotic stress
ontology: BP
definition:
Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


go_id: GO:0032062
term: positive regulation of translation in response to osmotic stress
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


go_id: GO:0032063
term: negative regulation of translational initiation in response to osmotic stress
ontology: BP
definition:
Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


go_id: GO:0032064
term: positive regulation of translational initiation in response to osmotic stress
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


go_id: GO:0032065
term: cortical protein anchoring
ontology: BP
definition:
A process in which a protein or protein complex is maintained in a specific location in the cell cortex.


go_id: GO:0032067
term: Type IV site-specific deoxyribonuclease activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated).


go_id: GO:0032068
term: Type IV site-specific deoxyribonuclease complex
ontology: CC
definition:
A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation.


go_id: GO:0032069
term: regulation of nuclease activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


go_id: GO:0032070
term: regulation of deoxyribonuclease activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


go_id: GO:0032071
term: regulation of endodeoxyribonuclease activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


go_id: GO:0032072
term: regulation of restriction endodeoxyribonuclease activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


go_id: GO:0032073
term: negative regulation of restriction endodeoxyribonuclease activity
ontology: BP
definition:
Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


go_id: GO:0032074
term: negative regulation of nuclease activity
ontology: BP
definition:
Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


go_id: GO:0032075
term: positive regulation of nuclease activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


go_id: GO:0032076
term: negative regulation of deoxyribonuclease activity
ontology: BP
definition:
Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


go_id: GO:0032077
term: positive regulation of deoxyribonuclease activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


go_id: GO:0032078
term: negative regulation of endodeoxyribonuclease activity
ontology: BP
definition:
Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


go_id: GO:0032079
term: positive regulation of endodeoxyribonuclease activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.


go_id: GO:0032084
term: regulation of Type I site-specific deoxyribonuclease activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a Type I restriction endodeoxyribonuclease activity.


go_id: GO:0032085
term: regulation of Type II site-specific deoxyribonuclease activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a Type II restriction endodeoxyribonuclease activity.


go_id: GO:0032086
term: regulation of Type III site-specific deoxyribonuclease activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a Type III restriction endodeoxyribonuclease activity.


go_id: GO:0032087
term: regulation of Type IV site-specific deoxyribonuclease activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a Type IV restriction endodeoxyribonuclease activity.


go_id: GO:0032088
term: negative regulation of NF-kappaB transcription factor activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.


go_id: GO:0032089
term: NACHT domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg(2+)-binding site and five more specific motifs.


go_id: GO:0032090
term: Pyrin domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain.


go_id: GO:0032093
term: SAM domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes.


go_id: GO:0032094
term: response to food
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.


go_id: GO:0032096
term: negative regulation of response to food
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus.


go_id: GO:0032102
term: negative regulation of response to external stimulus
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.


go_id: GO:0032104
term: regulation of response to extracellular stimulus
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus.


go_id: GO:0032105
term: negative regulation of response to extracellular stimulus
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus.


go_id: GO:0032106
term: positive regulation of response to extracellular stimulus
ontology: BP
definition:
Any process that activates, maintains or increases the rate of a response to an extracellular stimulus.


go_id: GO:0032108
term: negative regulation of response to nutrient levels
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.


go_id: GO:0032109
term: positive regulation of response to nutrient levels
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of a response to nutrient levels.


go_id: GO:0032112
term: negative regulation of protein histidine kinase activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity.


go_id: GO:0032113
term: regulation of carbohydrate phosphatase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate.


go_id: GO:0032114
term: regulation of glucose-6-phosphatase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate.


go_id: GO:0032115
term: sorbose reductase activity
ontology: MF
definition:
Catalysis of the reaction: D-glucitol + NADP(+) = L-sorbose + H(+) + NADPH. The reaction may occur, to a minor extent, in the reverse direction.


go_id: GO:0032116
term: SMC loading complex
ontology: CC
definition:
A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved.


go_id: GO:0032117
term: horsetail-astral microtubule array
ontology: CC
definition:
An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement.


go_id: GO:0032118
term: horsetail-astral microtubule organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis.


go_id: GO:0032119
term: sequestering of zinc ion
ontology: BP
definition:
The process of binding or confining zinc ions such that they are separated from other components of a biological system.


go_id: GO:0032120
term: ascospore-type prospore membrane assembly
ontology: BP
definition:
The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.


go_id: GO:0032121
term: attachment of telomeric heterochromatin to spindle pole body
ontology: BP
definition:
The cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation.


go_id: GO:0032122
term: oral apparatus organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans.


go_id: GO:0032123
term: deep fiber
ontology: CC
definition:
Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm.


go_id: GO:0032124
term: macronucleus organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus.


go_id: GO:0032125
term: micronucleus organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus.


go_id: GO:0032126
term: eisosome
ontology: CC
definition:
A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization.


go_id: GO:0032128
term: flocculation via extracellular polymer
ontology: BP
definition:
Non-sexual aggregation of single-celled organisms mediated by polymers (polysaccharides, proteins, and/or nucleic acids) secreted into the extracellular environment.


go_id: GO:0032129
term: histone deacetylase activity (H3-K9 specific)
ontology: MF
definition:
Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.


go_id: GO:0032130
term: medial membrane band assembly
ontology: BP
definition:
The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring.


go_id: GO:0032133
term: chromosome passenger complex
ontology: CC
definition:
A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin.


go_id: GO:0032135
term: DNA insertion or deletion binding
ontology: MF
definition:
Interacting selectively and non-covalently with double-stranded DNA containing insertions or deletions.


go_id: GO:0032138
term: single base insertion or deletion binding
ontology: MF
definition:
Interacting selectively and non-covalently with double-stranded DNA containing a single base insertion or deletion.


go_id: GO:0032139
term: dinucleotide insertion or deletion binding
ontology: MF
definition:
Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide insertion or deletion.


go_id: GO:0032140
term: single adenine insertion binding
ontology: MF
definition:
Interacting selectively and non-covalently with double-stranded DNA containing a single adenine insertion or a deletion that results in an unpaired adenine.


go_id: GO:0032141
term: single cytosine insertion binding
ontology: MF
definition:
Interacting selectively and non-covalently with double-stranded DNA containing a single cytosine insertion or a deletion that results in an unpaired cytosine.


go_id: GO:0032142
term: single guanine insertion binding
ontology: MF
definition:
Interacting selectively and non-covalently with double-stranded DNA containing a single guanine insertion or a deletion that results in an unpaired guanine.


go_id: GO:0032143
term: single thymine insertion binding
ontology: MF
definition:
Interacting selectively and non-covalently with double-stranded DNA containing a single thymine insertion or a deletion that results in an unpaired thymine.


go_id: GO:0032146
term: thiosulfate transmembrane-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in).


go_id: GO:0032149
term: response to rhamnose
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.


go_id: GO:0032150
term: ubiquinone biosynthetic process from chorismate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.


go_id: GO:0032153
term: cell division site
ontology: CC
definition:
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.


go_id: GO:0032154
term: cleavage furrow
ontology: CC
definition:
In animal cells, the first sign of cleavage, or cytokinesis, is the appearance of a shallow groove in the cell surface near the old metaphase plate. A contractile ring containing actin and myosin is located just inside the plasma membrane at the location of the furrow. Ring contraction is associated with centripetal growth of the membrane that deepens the cleavage furrow and divides the cytoplasm of the two daughter cells. While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists.


go_id: GO:0032155
term: cell division site part
ontology: CC
definition:
Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell.


go_id: GO:0032156
term: septin cytoskeleton
ontology: CC
definition:
The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes.


go_id: GO:0032157
term: prospore contractile ring
ontology: CC
definition:
A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis.


go_id: GO:0032158
term: septin band
ontology: CC
definition:
A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.


go_id: GO:0032159
term: septin cap
ontology: CC
definition:
A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.


go_id: GO:0032160
term: septin filament array
ontology: CC
definition:
Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans.


go_id: GO:0032161
term: cleavage apparatus septin structure
ontology: CC
definition:
Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis.


go_id: GO:0032162
term: mating projection septin band
ontology: CC
definition:
A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection).


go_id: GO:0032163
term: hyphal septin band
ontology: CC
definition:
A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.


go_id: GO:0032164
term: hyphal septin cap
ontology: CC
definition:
A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.


go_id: GO:0032165
term: prospore septin filament array
ontology: CC
definition:
Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation.


go_id: GO:0032166
term: chlamydospore septin filament array
ontology: CC
definition:
Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation.


go_id: GO:0032168
term: hyphal septin ring
ontology: CC
definition:
A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.


go_id: GO:0032169
term: prospore septin ring
ontology: CC
definition:
A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins.


go_id: GO:0032170
term: pseudohyphal septin ring
ontology: CC
definition:
A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins.


go_id: GO:0032171
term: germ tube septin cap
ontology: CC
definition:
A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.


go_id: GO:0032172
term: germ tube septin ring
ontology: CC
definition:
A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.


go_id: GO:0032173
term: septin collar
ontology: CC
definition:
A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell.


go_id: GO:0032174
term: cellular bud neck septin collar
ontology: CC
definition:
A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck.


go_id: GO:0032175
term: mating projection septin ring
ontology: CC
definition:
A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip.


go_id: GO:0032176
term: split septin rings
ontology: CC
definition:
A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well.


go_id: GO:0032177
term: cellular bud neck split septin rings
ontology: CC
definition:
Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated.


go_id: GO:0032178
term: medial membrane band
ontology: CC
definition:
A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum.


go_id: GO:0032180
term: ubiquinone biosynthetic process from tyrosine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate.


go_id: GO:0032181
term: dinucleotide repeat insertion binding
ontology: MF
definition:
Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats.


go_id: GO:0032182
term: ubiquitin-like protein binding
ontology: MF
definition:
Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein.


go_id: GO:0032185
term: septin cytoskeleton organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins.


go_id: GO:0032186
term: cellular bud neck septin ring organization
ontology: BP
definition:
Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck.


go_id: GO:0032187
term: actomyosin contractile ring localization
ontology: BP
definition:
The process in which a contractile ring is assembled and/or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle.


go_id: GO:0032188
term: establishment of actomyosin contractile ring localization
ontology: BP
definition:
The process in which a contractile ring is assembled in a specific location as part of a process of cell cycle cytokinesis.


go_id: GO:0032189
term: maintenance of actomyosin contractile ring localization
ontology: BP
definition:
Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere.


go_id: GO:0032190
term: acrosin binding
ontology: MF
definition:
Interacting selectively and non-covalently with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities.


go_id: GO:0032193
term: ubiquinone biosynthetic process via 2-polyprenylphenol
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol.


go_id: GO:0032194
term: ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate.


go_id: GO:0032195
term: post-lysosomal vacuole
ontology: CC
definition:
A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.


go_id: GO:0032196
term: transposition
ontology: BP
definition:
Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.


go_id: GO:0032197
term: transposition, RNA-mediated
ontology: BP
definition:
Any process involved in a type of transpositional recombination which occurs via an RNA intermediate.


go_id: GO:0032198
term: MITE transposition
ontology: BP
definition:
Any process involved in the transposition of miniature inverted-repeat transposable elements (MITEs).


go_id: GO:0032200
term: telomere organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins.


go_id: GO:0032201
term: telomere maintenance via semi-conservative replication
ontology: BP
definition:
The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication.


go_id: GO:0032202
term: telomere assembly
ontology: BP
definition:
A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins.


go_id: GO:0032204
term: regulation of telomere maintenance
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.


go_id: GO:0032205
term: negative regulation of telomere maintenance
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.


go_id: GO:0032206
term: positive regulation of telomere maintenance
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.


go_id: GO:0032207
term: regulation of telomere maintenance via recombination
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.


go_id: GO:0032208
term: negative regulation of telomere maintenance via recombination
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.


go_id: GO:0032209
term: positive regulation of telomere maintenance via recombination
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.


go_id: GO:0032210
term: regulation of telomere maintenance via telomerase
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.


go_id: GO:0032211
term: negative regulation of telomere maintenance via telomerase
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.


go_id: GO:0032212
term: positive regulation of telomere maintenance via telomerase
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.


go_id: GO:0032213
term: regulation of telomere maintenance via semi-conservative replication
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA.


go_id: GO:0032214
term: negative regulation of telomere maintenance via semi-conservative replication
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA.


go_id: GO:0032215
term: positive regulation of telomere maintenance via semi-conservative replication
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA.


go_id: GO:0032216
term: glucosaminyl-phosphotidylinositol O-acyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: glucosaminyl-phosphotidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phosphotidylinositol + CoA.


go_id: GO:0032217
term: riboflavin transporter activity
ontology: MF
definition:
Enables the directed movement of riboflavin into, out of or within a cell, or between cells. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.


go_id: GO:0032218
term: riboflavin transport
ontology: BP
definition:
The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.


go_id: GO:0032219
term: cell wall macromolecule catabolic process involved in cytogamy
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy.


go_id: GO:0032220
term: plasma membrane fusion involved in cytogamy
ontology: BP
definition:
The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy.


go_id: GO:0032221
term: Rpd3S complex
ontology: CC
definition:
A eukaryotically conserved histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species).


go_id: GO:0032222
term: regulation of synaptic transmission, cholinergic
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.


go_id: GO:0032223
term: negative regulation of synaptic transmission, cholinergic
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.


go_id: GO:0032224
term: positive regulation of synaptic transmission, cholinergic
ontology: BP
definition:
Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.


go_id: GO:0032225
term: regulation of synaptic transmission, dopaminergic
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.


go_id: GO:0032226
term: positive regulation of synaptic transmission, dopaminergic
ontology: BP
definition:
Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.


go_id: GO:0032227
term: negative regulation of synaptic transmission, dopaminergic
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.


go_id: GO:0032228
term: regulation of synaptic transmission, GABAergic
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).


go_id: GO:0032229
term: negative regulation of synaptic transmission, GABAergic
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).


go_id: GO:0032230
term: positive regulation of synaptic transmission, GABAergic
ontology: BP
definition:
Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).


go_id: GO:0032232
term: negative regulation of actin filament bundle assembly
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles.


go_id: GO:0032233
term: positive regulation of actin filament bundle assembly
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.


go_id: GO:0032238
term: adenosine transport
ontology: BP
definition:
The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032239
term: regulation of nucleobase-containing compound transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032240
term: negative regulation of nucleobase-containing compound transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032241
term: positive regulation of nucleobase-containing compound transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032242
term: regulation of nucleoside transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032243
term: negative regulation of nucleoside transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032244
term: positive regulation of nucleoside transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032245
term: regulation of purine nucleoside transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032246
term: regulation of pyrimidine nucleoside transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032247
term: negative regulation of purine nucleoside transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032248
term: positive regulation of purine nucleoside transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032249
term: regulation of adenosine transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032250
term: negative regulation of adenosine transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032251
term: positive regulation of adenosine transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032252
term: secretory granule localization
ontology: BP
definition:
Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.


go_id: GO:0032253
term: dense core granule localization
ontology: BP
definition:
Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.


go_id: GO:0032255
term: maintenance of secretory granule location
ontology: BP
definition:
Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere.


go_id: GO:0032257
term: maintenance of dense core granule location
ontology: BP
definition:
Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere.


go_id: GO:0032258
term: CVT pathway
ontology: BP
definition:
A constitutive biosynthetic process that occurs under nutrient-rich conditions, in which two resident vacuolar hydrolases, aminopeptidase I and alpha-mannosidase, are sequestered into vesicles; these vesicles are transported to, and then fuse with, the vacuole. This pathway is mostly observed in yeast.


go_id: GO:0032260
ontology: BP
term:
response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance

definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.


go_id: GO:0032262
term: pyrimidine nucleotide salvage
ontology: BP
definition:
Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis.


go_id: GO:0032263
term: GMP salvage
ontology: BP
definition:
Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.


go_id: GO:0032265
term: XMP salvage
ontology: BP
definition:
Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis.


go_id: GO:0032266
term: phosphatidylinositol-3-phosphate binding
ontology: MF
definition:
Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.


go_id: GO:0032267
term: tRNA(Ile)-lysidine synthase activity
ontology: MF
definition:
Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine.


go_id: GO:0032268
term: regulation of cellular protein metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.


go_id: GO:0032269
term: negative regulation of cellular protein metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.


go_id: GO:0032270
term: positive regulation of cellular protein metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.


go_id: GO:0032271
term: regulation of protein polymerization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the process of creating protein polymers.


go_id: GO:0032272
term: negative regulation of protein polymerization
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.


go_id: GO:0032273
term: positive regulation of protein polymerization
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.


go_id: GO:0032274
term: gonadotropin secretion
ontology: BP
definition:
The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone.


go_id: GO:0032275
term: luteinizing hormone secretion
ontology: BP
definition:
The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.


go_id: GO:0032276
term: regulation of gonadotropin secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin.


go_id: GO:0032277
term: negative regulation of gonadotropin secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin.


go_id: GO:0032278
term: positive regulation of gonadotropin secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin.


go_id: GO:0032279
term: asymmetric synapse
ontology: CC
definition:
A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density.


go_id: GO:0032280
term: symmetric synapse
ontology: CC
definition:
A type of synapse occurring primarily on dendrite shafts and neuronal cell bodies. Symmetric synapses involve axons containing clusters of predominantly flattened or elongated vesicles and do not contain a prominent postsynaptic density.


go_id: GO:0032281
term: AMPA glutamate receptor complex
ontology: CC
definition:
An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.


go_id: GO:0032286
term: central nervous system myelin maintenance
ontology: BP
definition:
The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.


go_id: GO:0032287
term: peripheral nervous system myelin maintenance
ontology: BP
definition:
The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.


go_id: GO:0032288
term: myelin assembly
ontology: BP
definition:
The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.


go_id: GO:0032289
term: central nervous system myelin formation
ontology: BP
definition:
The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.


go_id: GO:0032290
term: peripheral nervous system myelin formation
ontology: BP
definition:
The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the peripheral nervous system.


go_id: GO:0032291
term: axon ensheathment in central nervous system
ontology: BP
definition:
The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.


go_id: GO:0032292
term: peripheral nervous system axon ensheathment
ontology: BP
definition:
The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.


go_id: GO:0032293
term: non-myelinated axon ensheathment in central nervous system
ontology: BP
definition:
The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system.


go_id: GO:0032294
term: peripheral nervous system non-myelinated axon ensheathment
ontology: BP
definition:
The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons.


go_id: GO:0032297
term: negative regulation of DNA-dependent DNA replication initiation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.


go_id: GO:0032298
term: positive regulation of DNA-dependent DNA replication initiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.


go_id: GO:0032299
term: ribonuclease H2 complex
ontology: CC
definition:
A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p.


go_id: GO:0032301
term: MutSalpha complex
ontology: CC
definition:
A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.


go_id: GO:0032302
term: MutSbeta complex
ontology: CC
definition:
A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3.


go_id: GO:0032303
term: regulation of icosanoid secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell.


go_id: GO:0032304
term: negative regulation of icosanoid secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.


go_id: GO:0032305
term: positive regulation of icosanoid secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell.


go_id: GO:0032306
term: regulation of prostaglandin secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell.


go_id: GO:0032307
term: negative regulation of prostaglandin secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.


go_id: GO:0032308
term: positive regulation of prostaglandin secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell.


go_id: GO:0032309
term: icosanoid secretion
ontology: BP
definition:
The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue.


go_id: GO:0032310
term: prostaglandin secretion
ontology: BP
definition:
The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.


go_id: GO:0032311
term: angiogenin-PRI complex
ontology: CC
definition:
A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis.


go_id: GO:0032322
term: ubiquinone catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme.


go_id: GO:0032324
term: molybdopterin cofactor biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.


go_id: GO:0032325
term: molybdopterin cofactor catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.


go_id: GO:0032326
term: Mo-molybdopterin cofactor catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.


go_id: GO:0032327
term: W-molybdopterin cofactor catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.


go_id: GO:0032328
term: alanine transport
ontology: BP
definition:
The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032329
term: serine transport
ontology: BP
definition:
The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032331
term: negative regulation of chondrocyte differentiation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.


go_id: GO:0032332
term: positive regulation of chondrocyte differentiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.


go_id: GO:0032333
term: activin secretion
ontology: BP
definition:
The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.


go_id: GO:0032334
term: inhibin secretion
ontology: BP
definition:
The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.


go_id: GO:0032335
term: regulation of activin secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell.


go_id: GO:0032336
term: negative regulation of activin secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell.


go_id: GO:0032337
term: positive regulation of activin secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell.


go_id: GO:0032338
term: regulation of inhibin secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell.


go_id: GO:0032339
term: negative regulation of inhibin secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell.


go_id: GO:0032340
term: positive regulation of inhibin secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell.


go_id: GO:0032341
term: aldosterone metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.


go_id: GO:0032342
term: aldosterone biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.


go_id: GO:0032343
term: aldosterone catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.


go_id: GO:0032344
term: regulation of aldosterone metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.


go_id: GO:0032345
term: negative regulation of aldosterone metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.


go_id: GO:0032346
term: positive regulation of aldosterone metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.


go_id: GO:0032347
term: regulation of aldosterone biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.


go_id: GO:0032348
term: negative regulation of aldosterone biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.


go_id: GO:0032349
term: positive regulation of aldosterone biosynthetic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.


go_id: GO:0032350
term: regulation of hormone metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.


go_id: GO:0032351
term: negative regulation of hormone metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.


go_id: GO:0032352
term: positive regulation of hormone metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.


go_id: GO:0032353
term: negative regulation of hormone biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.


go_id: GO:0032354
term: response to follicle-stimulating hormone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.


go_id: GO:0032355
term: response to estradiol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.


go_id: GO:0032361
term: pyridoxal phosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.


go_id: GO:0032363
term: FMN catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.


go_id: GO:0032364
term: oxygen homeostasis
ontology: BP
definition:
A homeostatic process involved in the maintenance of an internal steady state of oxygen within an organism or cell.


go_id: GO:0032368
term: regulation of lipid transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032369
term: negative regulation of lipid transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032370
term: positive regulation of lipid transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032371
term: regulation of sterol transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032372
term: negative regulation of sterol transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032373
term: positive regulation of sterol transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032374
term: regulation of cholesterol transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032375
term: negative regulation of cholesterol transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032376
term: positive regulation of cholesterol transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032377
term: regulation of intracellular lipid transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.


go_id: GO:0032378
term: negative regulation of intracellular lipid transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.


go_id: GO:0032379
term: positive regulation of intracellular lipid transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.


go_id: GO:0032380
term: regulation of intracellular sterol transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells.


go_id: GO:0032381
term: negative regulation of intracellular sterol transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells.


go_id: GO:0032382
term: positive regulation of intracellular sterol transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells.


go_id: GO:0032383
term: regulation of intracellular cholesterol transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.


go_id: GO:0032384
term: negative regulation of intracellular cholesterol transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells.


go_id: GO:0032385
term: positive regulation of intracellular cholesterol transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.


go_id: GO:0032386
term: regulation of intracellular transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.


go_id: GO:0032387
term: negative regulation of intracellular transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.


go_id: GO:0032388
term: positive regulation of intracellular transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.


go_id: GO:0032389
term: MutLalpha complex
ontology: CC
definition:
A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.


go_id: GO:0032390
term: MutLbeta complex
ontology: CC
definition:
A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1.


go_id: GO:0032391
term: photoreceptor connecting cilium
ontology: CC
definition:
A nonmotile primary cilium that has a 9+0 microtubule array and forms the portion of the axoneme traversing the boundary between the photoreceptor inner and outer segments.


go_id: GO:0032392
term: DNA geometric change
ontology: BP
definition:
The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.


go_id: GO:0032396
term: inhibitory MHC class I receptor activity
ontology: MF
definition:
Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte.


go_id: GO:0032398
term: MHC class Ib protein complex
ontology: CC
definition:
A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.


go_id: GO:0032399
term: HECT domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a HECT, 'Homologous to the E6-AP Carboxyl Terminus', domain of a protein.


go_id: GO:0032400
term: melanosome localization
ontology: BP
definition:
Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.


go_id: GO:0032402
term: melanosome transport
ontology: BP
definition:
The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032403
term: protein complex binding
ontology: MF
definition:
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).


go_id: GO:0032415
term: regulation of sodium:proton antiporter activity
ontology: BP
definition:
Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).


go_id: GO:0032416
term: negative regulation of sodium:proton antiporter activity
ontology: BP
definition:
Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).


go_id: GO:0032417
term: positive regulation of sodium:proton antiporter activity
ontology: BP
definition:
Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).


go_id: GO:0032419
term: extrinsic component of lysosome membrane
ontology: CC
definition:
The component of an lysosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


go_id: GO:0032420
term: stereocilium
ontology: CC
definition:
An actin-based protrusion from the apical surface of auditory and vestibular hair cells. Bundles of stereocilia act as mechanosensory organelles.


go_id: GO:0032421
term: stereocilium bundle
ontology: CC
definition:
An actin-based, cross-linked cellular protrusion on the apical surface of auditory and vestibular hair cells. Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes.


go_id: GO:0032422
term: purine-rich negative regulatory element binding
ontology: MF
definition:
Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.


go_id: GO:0032426
term: stereocilium bundle tip
ontology: CC
definition:
The end of a stereocilium bundle, distal to the site of the bundle's attachment to the apical cell surface.


go_id: GO:0032427
term: GBD domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with the GTPase protein binding domain (GDB) domain of a protein. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac.


go_id: GO:0032428
term: beta-N-acetylgalactosaminidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.


go_id: GO:0032432
term: actin filament bundle
ontology: CC
definition:
An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.


go_id: GO:0032434
term: regulation of proteasomal ubiquitin-dependent protein catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.


go_id: GO:0032435
term: negative regulation of proteasomal ubiquitin-dependent protein catabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.


go_id: GO:0032436
term: positive regulation of proteasomal ubiquitin-dependent protein catabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.


go_id: GO:0032437
term: cuticular plate
ontology: CC
definition:
A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.


go_id: GO:0032438
term: melanosome organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.


go_id: GO:0032439
term: endosome localization
ontology: BP
definition:
Any process in which endosomes are transported to, and/or maintained in, a specific location within the cell.


go_id: GO:0032441
term: pheophorbide a oxygenase activity
ontology: MF
definition:
Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O.


go_id: GO:0032442
term: phenylcoumaran benzylic ether reductase activity
ontology: MF
definition:
Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+.


go_id: GO:0032443
term: regulation of ergosterol biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.


go_id: GO:0032444
term: activin responsive factor complex
ontology: CC
definition:
A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor.


go_id: GO:0032446
term: protein modification by small protein conjugation
ontology: BP
definition:
A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.


go_id: GO:0032448
term: DNA hairpin binding
ontology: MF
definition:
Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences.


go_id: GO:0032449
term: CBM complex
ontology: CC
definition:
A protein complex comprising Carma1, Bcl10 and MALT1; plays a role in signal transduction during NF-kappaB activation.


go_id: GO:0032454
term: histone demethylase activity (H3-K9 specific)
ontology: MF
definition:
Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 9 of the histone H3 protein.


go_id: GO:0032456
term: endocytic recycling
ontology: BP
definition:
The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport.


go_id: GO:0032457
term: fast endocytic recycling
ontology: BP
definition:
The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.


go_id: GO:0032458
term: slow endocytic recycling
ontology: BP
definition:
The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.


go_id: GO:0032460
term: negative regulation of protein oligomerization
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.


go_id: GO:0032463
term: negative regulation of protein homooligomerization
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization.


go_id: GO:0032464
term: positive regulation of protein homooligomerization
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of protein homooligomerization.


go_id: GO:0032465
term: regulation of cytokinesis
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.


go_id: GO:0032466
term: negative regulation of cytokinesis
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.


go_id: GO:0032467
term: positive regulation of cytokinesis
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.


go_id: GO:0032468
term: Golgi calcium ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.


go_id: GO:0032469
term: endoplasmic reticulum calcium ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings.


go_id: GO:0032475
term: otolith formation
ontology: BP
definition:
The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.


go_id: GO:0032476
term: decaprenyl diphosphate synthase complex
ontology: CC
definition:
A complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.


go_id: GO:0032477
term: homodimeric decaprenyl diphosphate synthase complex
ontology: CC
definition:
A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.


go_id: GO:0032478
term: heterotetrameric decaprenyl diphosphate synthase complex
ontology: CC
definition:
A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1.


go_id: GO:0032479
term: regulation of type I interferon production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0032480
term: negative regulation of type I interferon production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0032481
term: positive regulation of type I interferon production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0032482
term: Rab protein signal transduction
ontology: BP
definition:
A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.


go_id: GO:0032484
term: Ral protein signal transduction
ontology: BP
definition:
A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state.


go_id: GO:0032486
term: Rap protein signal transduction
ontology: BP
definition:
A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.


go_id: GO:0032488
term: Cdc42 protein signal transduction
ontology: BP
definition:
A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state.


go_id: GO:0032490
term: detection of molecule of bacterial origin
ontology: BP
definition:
The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal.


go_id: GO:0032491
term: detection of molecule of fungal origin
ontology: BP
definition:
The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal.


go_id: GO:0032492
term: detection of molecule of oomycetes origin
ontology: BP
definition:
The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal.


go_id: GO:0032493
term: response to bacterial lipoprotein
ontology: BP
definition:
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.


go_id: GO:0032494
term: response to peptidoglycan
ontology: BP
definition:
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.


go_id: GO:0032495
term: response to muramyl dipeptide
ontology: BP
definition:
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.


go_id: GO:0032496
term: response to lipopolysaccharide
ontology: BP
definition:
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.


go_id: GO:0032497
term: detection of lipopolysaccharide
ontology: BP
definition:
The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.


go_id: GO:0032498
term: detection of muramyl dipeptide
ontology: BP
definition:
The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan.


go_id: GO:0032499
term: detection of peptidoglycan
ontology: BP
definition:
The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule.


go_id: GO:0032500
term: muramyl dipeptide binding
ontology: MF
definition:
Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan.


go_id: GO:0032501
term: multicellular organismal process
ontology: BP
definition:
Any biological process, occurring at the level of a multicellular organism, pertinent to its function.


go_id: GO:0032502
term: developmental process
ontology: BP
definition:
A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.


go_id: GO:0032504
term: multicellular organism reproduction
ontology: BP
definition:
The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.


go_id: GO:0032505
term: reproduction of a single-celled organism
ontology: BP
definition:
The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.


go_id: GO:0032506
term: cytokinetic process
ontology: BP
definition:
A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).


go_id: GO:0032507
term: maintenance of protein location in cell
ontology: BP
definition:
Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.


go_id: GO:0032508
term: DNA duplex unwinding
ontology: BP
definition:
The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.


go_id: GO:0032509
term: endosome transport via multivesicular body sorting pathway
ontology: BP
definition:
The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.


go_id: GO:0032510
term: endosome to lysosome transport via multivesicular body sorting pathway
ontology: BP
definition:
The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.


go_id: GO:0032511
term: late endosome to vacuole transport via multivesicular body sorting pathway
ontology: BP
definition:
The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole.


go_id: GO:0032517
term: SOD1-calcineurin complex
ontology: CC
definition:
A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1.


go_id: GO:0032518
term: amino acid-exporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(in) -> ADP + phosphate + amino acid(out).


go_id: GO:0032519
term: cysteine-exporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(in) -> ADP + phosphate + cysteine(out).


go_id: GO:0032520
term: amino acid-importing ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out) -> ADP + phosphate + amino acid(in).


go_id: GO:0032521
term: D-methionine-exporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(in) -> ADP + phosphate + D-methionine(out).


go_id: GO:0032522
term: D-methionine-importing ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out) -> ADP + phosphate + D-methionine(in).


go_id: GO:0032523
term: silicon efflux transmembrane transporter activity
ontology: MF
definition:
Catalysis of the transfer of silicon from the inside of the cell to the outside of the cell across a membrane.


go_id: GO:0032525
term: somite rostral/caudal axis specification
ontology: BP
definition:
The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.


go_id: GO:0032526
term: response to retinoic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.


go_id: GO:0032528
term: microvillus organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.


go_id: GO:0032529
term: follicle cell microvillus organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments.


go_id: GO:0032530
term: regulation of microvillus organization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus.


go_id: GO:0032531
term: regulation of follicle cell microvillus organization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell.


go_id: GO:0032537
term: host-seeking behavior
ontology: BP
definition:
The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host.


go_id: GO:0032538
term: regulation of host-seeking behavior
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism.


go_id: GO:0032539
term: negative regulation of host-seeking behavior
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism.


go_id: GO:0032540
term: positive regulation of host-seeking behavior
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism.


go_id: GO:0032541
term: cortical endoplasmic reticulum
ontology: CC
definition:
A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.


go_id: GO:0032542
term: sulfiredoxin activity
ontology: MF
definition:
Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R.


go_id: GO:0032543
term: mitochondrial translation
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.


go_id: GO:0032544
term: plastid translation
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.


go_id: GO:0032545
term: CURI complex
ontology: CC
definition:
A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p.


go_id: GO:0032546
term: deoxyribonucleoside binding
ontology: MF
definition:
Interacting selectively and non-covalently with a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose.


go_id: GO:0032547
term: purine deoxyribonucleoside binding
ontology: MF
definition:
Interacting selectively and non-covalently with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose.


go_id: GO:0032548
term: pyrimidine deoxyribonucleoside binding
ontology: MF
definition:
Interacting selectively and non-covalently with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.


go_id: GO:0032549
term: ribonucleoside binding
ontology: MF
definition:
Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.


go_id: GO:0032550
term: purine ribonucleoside binding
ontology: MF
definition:
Interacting selectively and non-covalently with a purine ribonucleoside, a compound consisting of a purine base linked to ribose.


go_id: GO:0032551
term: pyrimidine ribonucleoside binding
ontology: MF
definition:
Interacting selectively and non-covalently with a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose.


go_id: GO:0032552
term: deoxyribonucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.


go_id: GO:0032553
term: ribonucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.


go_id: GO:0032554
term: purine deoxyribonucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.


go_id: GO:0032555
term: purine ribonucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.


go_id: GO:0032556
term: pyrimidine deoxyribonucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.


go_id: GO:0032557
term: pyrimidine ribonucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.


go_id: GO:0032558
term: adenyl deoxyribonucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.


go_id: GO:0032559
term: adenyl ribonucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.


go_id: GO:0032560
term: guanyl deoxyribonucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.


go_id: GO:0032561
term: guanyl ribonucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.


go_id: GO:0032570
term: response to progesterone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.


go_id: GO:0032571
term: response to vitamin K
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.


go_id: GO:0032572
term: response to menaquinone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.


go_id: GO:0032573
term: response to phylloquinone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.


go_id: GO:0032575
term: ATP-dependent 5'-3' RNA helicase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 5' to 3'.


go_id: GO:0032576
term: O-linoleoyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule.


go_id: GO:0032577
term: phosphatidylcholine:cardiolipin O-linoleoyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule.


go_id: GO:0032579
term: apical lamina of hyaline layer
ontology: CC
definition:
A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms.


go_id: GO:0032580
term: Golgi cisterna membrane
ontology: CC
definition:
The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.


go_id: GO:0032581
term: ER-dependent peroxisome organization
ontology: BP
definition:
A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum.


go_id: GO:0032592
term: integral component of mitochondrial membrane
ontology: CC
definition:
The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.


go_id: GO:0032593
term: insulin-responsive compartment
ontology: CC
definition:
A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.


go_id: GO:0032596
term: protein transport into membrane raft
ontology: BP
definition:
The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


go_id: GO:0032599
term: protein transport out of membrane raft
ontology: BP
definition:
The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


go_id: GO:0032601
term: connective tissue growth factor production
ontology: BP
definition:
The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032602
term: chemokine production
ontology: BP
definition:
The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032603
term: fractalkine production
ontology: BP
definition:
The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032604
term: granulocyte macrophage colony-stimulating factor production
ontology: BP
definition:
The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032605
term: hepatocyte growth factor production
ontology: BP
definition:
The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032606
term: type I interferon production
ontology: BP
definition:
The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0032607
term: interferon-alpha production
ontology: BP
definition:
The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032608
term: interferon-beta production
ontology: BP
definition:
The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032609
term: interferon-gamma production
ontology: BP
definition:
The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.


go_id: GO:0032610
term: interleukin-1 alpha production
ontology: BP
definition:
The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032611
term: interleukin-1 beta production
ontology: BP
definition:
The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032612
term: interleukin-1 production
ontology: BP
definition:
The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032613
term: interleukin-10 production
ontology: BP
definition:
The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032614
term: interleukin-11 production
ontology: BP
definition:
The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032615
term: interleukin-12 production
ontology: BP
definition:
The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032616
term: interleukin-13 production
ontology: BP
definition:
The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032617
term: interleukin-14 production
ontology: BP
definition:
The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032618
term: interleukin-15 production
ontology: BP
definition:
The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032619
term: interleukin-16 production
ontology: BP
definition:
The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032620
term: interleukin-17 production
ontology: BP
definition:
The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032621
term: interleukin-18 production
ontology: BP
definition:
The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032622
term: interleukin-19 production
ontology: BP
definition:
The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032623
term: interleukin-2 production
ontology: BP
definition:
The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032624
term: interleukin-20 production
ontology: BP
definition:
The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032625
term: interleukin-21 production
ontology: BP
definition:
The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032626
term: interleukin-22 production
ontology: BP
definition:
The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032627
term: interleukin-23 production
ontology: BP
definition:
The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032628
term: interleukin-24 production
ontology: BP
definition:
The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032629
term: interleukin-25 production
ontology: BP
definition:
The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032630
term: interleukin-26 production
ontology: BP
definition:
The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032631
term: interleukin-27 production
ontology: BP
definition:
The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032632
term: interleukin-3 production
ontology: BP
definition:
The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032633
term: interleukin-4 production
ontology: BP
definition:
The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032634
term: interleukin-5 production
ontology: BP
definition:
The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032635
term: interleukin-6 production
ontology: BP
definition:
The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032636
term: interleukin-7 production
ontology: BP
definition:
The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032637
term: interleukin-8 production
ontology: BP
definition:
The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032638
term: interleukin-9 production
ontology: BP
definition:
The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032639
term: TRAIL production
ontology: BP
definition:
The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032640
term: tumor necrosis factor production
ontology: BP
definition:
The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032641
term: lymphotoxin A production
ontology: BP
definition:
The appearance of lymphotoxin A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032643
term: regulation of connective tissue growth factor production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of connective tissue growth factor production.


go_id: GO:0032645
term: regulation of granulocyte macrophage colony-stimulating factor production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.


go_id: GO:0032649
term: regulation of interferon-gamma production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.


go_id: GO:0032660
term: regulation of interleukin-17 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.


go_id: GO:0032682
term: negative regulation of chemokine production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production.


go_id: GO:0032683
term: negative regulation of connective tissue growth factor production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production.


go_id: GO:0032684
term: negative regulation of fractalkine production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production.


go_id: GO:0032685
term: negative regulation of granulocyte macrophage colony-stimulating factor production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.


go_id: GO:0032686
term: negative regulation of hepatocyte growth factor production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production.


go_id: GO:0032687
term: negative regulation of interferon-alpha production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.


go_id: GO:0032688
term: negative regulation of interferon-beta production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.


go_id: GO:0032689
term: negative regulation of interferon-gamma production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.


go_id: GO:0032690
term: negative regulation of interleukin-1 alpha production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production.


go_id: GO:0032691
term: negative regulation of interleukin-1 beta production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.


go_id: GO:0032692
term: negative regulation of interleukin-1 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production.


go_id: GO:0032693
term: negative regulation of interleukin-10 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production.


go_id: GO:0032694
term: negative regulation of interleukin-11 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production.


go_id: GO:0032695
term: negative regulation of interleukin-12 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.


go_id: GO:0032696
term: negative regulation of interleukin-13 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production.


go_id: GO:0032697
term: negative regulation of interleukin-14 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-14 production.


go_id: GO:0032698
term: negative regulation of interleukin-15 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production.


go_id: GO:0032699
term: negative regulation of interleukin-16 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production.


go_id: GO:0032700
term: negative regulation of interleukin-17 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.


go_id: GO:0032701
term: negative regulation of interleukin-18 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production.


go_id: GO:0032702
term: negative regulation of interleukin-19 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production.


go_id: GO:0032703
term: negative regulation of interleukin-2 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.


go_id: GO:0032704
term: negative regulation of interleukin-20 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production.


go_id: GO:0032705
term: negative regulation of interleukin-21 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production.


go_id: GO:0032706
term: negative regulation of interleukin-22 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production.


go_id: GO:0032707
term: negative regulation of interleukin-23 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production.


go_id: GO:0032708
term: negative regulation of interleukin-24 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production.


go_id: GO:0032709
term: negative regulation of interleukin-25 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production.


go_id: GO:0032710
term: negative regulation of interleukin-26 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production.


go_id: GO:0032711
term: negative regulation of interleukin-27 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production.


go_id: GO:0032712
term: negative regulation of interleukin-3 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production.


go_id: GO:0032713
term: negative regulation of interleukin-4 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production.


go_id: GO:0032714
term: negative regulation of interleukin-5 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production.


go_id: GO:0032715
term: negative regulation of interleukin-6 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.


go_id: GO:0032716
term: negative regulation of interleukin-7 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production.


go_id: GO:0032717
term: negative regulation of interleukin-8 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production.


go_id: GO:0032718
term: negative regulation of interleukin-9 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production.


go_id: GO:0032720
term: negative regulation of tumor necrosis factor production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.


go_id: GO:0032721
term: negative regulation of lymphotoxin A production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production.


go_id: GO:0032723
term: positive regulation of connective tissue growth factor production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production.


go_id: GO:0032725
term: positive regulation of granulocyte macrophage colony-stimulating factor production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.


go_id: GO:0032726
term: positive regulation of hepatocyte growth factor production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production.


go_id: GO:0032727
term: positive regulation of interferon-alpha production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interferon-alpha production.


go_id: GO:0032728
term: positive regulation of interferon-beta production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interferon-beta production.


go_id: GO:0032729
term: positive regulation of interferon-gamma production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.


go_id: GO:0032730
term: positive regulation of interleukin-1 alpha production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production.


go_id: GO:0032731
term: positive regulation of interleukin-1 beta production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production.


go_id: GO:0032733
term: positive regulation of interleukin-10 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.


go_id: GO:0032734
term: positive regulation of interleukin-11 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-11 production.


go_id: GO:0032735
term: positive regulation of interleukin-12 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.


go_id: GO:0032736
term: positive regulation of interleukin-13 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.


go_id: GO:0032737
term: positive regulation of interleukin-14 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-14 production.


go_id: GO:0032738
term: positive regulation of interleukin-15 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-15 production.


go_id: GO:0032739
term: positive regulation of interleukin-16 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-16 production.


go_id: GO:0032740
term: positive regulation of interleukin-17 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.


go_id: GO:0032741
term: positive regulation of interleukin-18 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-18 production.


go_id: GO:0032742
term: positive regulation of interleukin-19 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-19 production.


go_id: GO:0032744
term: positive regulation of interleukin-20 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-20 production.


go_id: GO:0032745
term: positive regulation of interleukin-21 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-21 production.


go_id: GO:0032746
term: positive regulation of interleukin-22 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-22 production.


go_id: GO:0032747
term: positive regulation of interleukin-23 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-23 production.


go_id: GO:0032748
term: positive regulation of interleukin-24 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-24 production.


go_id: GO:0032749
term: positive regulation of interleukin-25 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-25 production.


go_id: GO:0032750
term: positive regulation of interleukin-26 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-26 production.


go_id: GO:0032751
term: positive regulation of interleukin-27 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interleukin-27 production.


go_id: GO:0032760
term: positive regulation of tumor necrosis factor production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.


go_id: GO:0032764
term: negative regulation of mast cell cytokine production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.


go_id: GO:0032765
term: positive regulation of mast cell cytokine production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production.


go_id: GO:0032766
term: NHE3/E3KARP/ACTN4 complex
ontology: CC
definition:
A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments.


go_id: GO:0032767
term: copper-dependent protein binding
ontology: MF
definition:
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper.


go_id: GO:0032771
term: regulation of monophenol monooxygenase activity
ontology: BP
definition:
Any process that modulates the activity of the enzyme monophenol monooxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.


go_id: GO:0032772
term: negative regulation of monophenol monooxygenase activity
ontology: BP
definition:
Any process that stops or reduces the activity of the enzyme monophenol monooxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.


go_id: GO:0032773
term: positive regulation of monophenol monooxygenase activity
ontology: BP
definition:
Any process that activates or increases the activity of the enzyme monophenol oxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.


go_id: GO:0032774
term: RNA biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.


go_id: GO:0032777
term: Piccolo NuA4 histone acetyltransferase complex
ontology: CC
definition:
A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p.


go_id: GO:0032778
term: cobalt-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in).


go_id: GO:0032782
term: bile acid secretion
ontology: BP
definition:
The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue.


go_id: GO:0032783
term: ELL-EAF complex
ontology: CC
definition:
A heterodimeric protein complex that acts as an RNA polymerase II elongation factor; the complex is conserved from yeast to humans, and is present in S. pombe, but absent from S. cerevisiae.


go_id: GO:0032787
term: monocarboxylic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).


go_id: GO:0032788
term: saturated monocarboxylic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds.


go_id: GO:0032789
term: unsaturated monocarboxylic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds.


go_id: GO:0032790
term: ribosome disassembly
ontology: BP
definition:
The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.


go_id: GO:0032792
term: negative regulation of CREB transcription factor activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB.


go_id: GO:0032793
term: positive regulation of CREB transcription factor activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB.


go_id: GO:0032796
term: uropod organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated.


go_id: GO:0032797
term: SMN complex
ontology: CC
definition:
A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus.


go_id: GO:0032798
term: Swi5-Sfr1 complex
ontology: CC
definition:
A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces).


go_id: GO:0032800
term: receptor biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


go_id: GO:0032801
term: receptor catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


go_id: GO:0032802
term: low-density lipoprotein particle receptor catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


go_id: GO:0032803
term: regulation of low-density lipoprotein particle receptor catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.


go_id: GO:0032804
term: negative regulation of low-density lipoprotein particle receptor catabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors.


go_id: GO:0032805
term: positive regulation of low-density lipoprotein particle receptor catabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.


go_id: GO:0032806
term: carboxy-terminal domain protein kinase complex
ontology: CC
definition:
A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5.


go_id: GO:0032807
term: DNA ligase IV complex
ontology: CC
definition:
A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p.


go_id: GO:0032808
term: lacrimal gland development
ontology: BP
definition:
The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye.


go_id: GO:0032809
term: neuronal cell body membrane
ontology: CC
definition:
The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.


go_id: GO:0032810
term: sterol response element binding
ontology: MF
definition:
Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.


go_id: GO:0032811
term: negative regulation of epinephrine secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.


go_id: GO:0032812
term: positive regulation of epinephrine secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine.


go_id: GO:0032813
term: tumor necrosis factor receptor superfamily binding
ontology: MF
definition:
Interacting selectively and non-covalently with any member of the tumor necrosis factor receptor superfamily.


go_id: GO:0032815
term: negative regulation of natural killer cell activation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.


go_id: GO:0032816
term: positive regulation of natural killer cell activation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of natural killer cell activation.


go_id: GO:0032818
term: negative regulation of natural killer cell proliferation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation.


go_id: GO:0032819
term: positive regulation of natural killer cell proliferation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation.


go_id: GO:0032820
term: regulation of natural killer cell proliferation involved in immune response
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response.


go_id: GO:0032821
term: negative regulation of natural killer cell proliferation involved in immune response
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response.


go_id: GO:0032822
term: positive regulation of natural killer cell proliferation involved in immune response
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response.


go_id: GO:0032824
term: negative regulation of natural killer cell differentiation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation.


go_id: GO:0032825
term: positive regulation of natural killer cell differentiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation.


go_id: GO:0032826
term: regulation of natural killer cell differentiation involved in immune response
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response.


go_id: GO:0032827
term: negative regulation of natural killer cell differentiation involved in immune response
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response.


go_id: GO:0032828
term: positive regulation of natural killer cell differentiation involved in immune response
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response.


go_id: GO:0032829
term: regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.


go_id: GO:0032830
term: negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.


go_id: GO:0032831
term: positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.


go_id: GO:0032832
ontology: BP
term:
regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

definition:
Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.


go_id: GO:0032833
ontology: BP
term:
negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.


go_id: GO:0032834
ontology: BP
term:
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response

definition:
Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.


go_id: GO:0032835
term: glomerulus development
ontology: BP
definition:
The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.


go_id: GO:0032836
term: glomerular basement membrane development
ontology: BP
definition:
The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration.


go_id: GO:0032837
term: distributive segregation
ontology: BP
definition:
The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a "backup" mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally.


go_id: GO:0032841
term: calcitonin binding
ontology: MF
definition:
Interacting selectively and non-covalently with calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid.


go_id: GO:0032843
term: hydroperoxide reductase activity
ontology: MF
definition:
Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.


go_id: GO:0032845
term: negative regulation of homeostatic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of a homeostatic process.


go_id: GO:0032847
term: regulation of cellular pH reduction
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell.


go_id: GO:0032848
term: negative regulation of cellular pH reduction
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell.


go_id: GO:0032849
term: positive regulation of cellular pH reduction
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.


go_id: GO:0032865
term: ERMES complex
ontology: CC
definition:
A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. The complex is also associated with actively replicating mitochondrial DNA nucleoids, and may further coordinate mitochondrial genome replication and membrane growth.


go_id: GO:0032868
term: response to insulin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.


go_id: GO:0032869
term: cellular response to insulin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.


go_id: GO:0032870
term: cellular response to hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.


go_id: GO:0032871
term: regulation of karyogamy
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.


go_id: GO:0032872
term: regulation of stress-activated MAPK cascade
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.


go_id: GO:0032873
term: negative regulation of stress-activated MAPK cascade
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.


go_id: GO:0032874
term: positive regulation of stress-activated MAPK cascade
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.


go_id: GO:0032876
term: negative regulation of DNA endoreduplication
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.


go_id: GO:0032878
term: regulation of establishment or maintenance of cell polarity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.


go_id: GO:0032879
term: regulation of localization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.


go_id: GO:0032880
term: regulation of protein localization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.


go_id: GO:0032881
term: regulation of polysaccharide metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.


go_id: GO:0032882
term: regulation of chitin metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin.


go_id: GO:0032883
term: regulation of chitin biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.


go_id: GO:0032884
term: regulation of cell wall chitin biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin.


go_id: GO:0032885
term: regulation of polysaccharide biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.


go_id: GO:0032886
term: regulation of microtubule-based process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.


go_id: GO:0032887
term: regulation of spindle elongation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle.


go_id: GO:0032888
term: regulation of mitotic spindle elongation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle.


go_id: GO:0032889
term: regulation of vacuole fusion, non-autophagic
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.


go_id: GO:0032890
term: regulation of organic acid transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032891
term: negative regulation of organic acid transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032892
term: positive regulation of organic acid transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032893
term: regulation of gluconate transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032894
term: negative regulation of gluconate transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032895
term: positive regulation of gluconate transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0032898
term: neurotrophin production
ontology: BP
definition:
The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.


go_id: GO:0032900
term: negative regulation of neurotrophin production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin.


go_id: GO:0032901
term: positive regulation of neurotrophin production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin.


go_id: GO:0032902
term: nerve growth factor production
ontology: BP
definition:
The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032903
term: regulation of nerve growth factor production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF).


go_id: GO:0032904
term: negative regulation of nerve growth factor production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).


go_id: GO:0032905
term: transforming growth factor beta1 production
ontology: BP
definition:
The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032906
term: transforming growth factor beta2 production
ontology: BP
definition:
The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032907
term: transforming growth factor beta3 production
ontology: BP
definition:
The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0032908
term: regulation of transforming growth factor beta1 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1.


go_id: GO:0032909
term: regulation of transforming growth factor beta2 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.


go_id: GO:0032910
term: regulation of transforming growth factor beta3 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3.


go_id: GO:0032911
term: negative regulation of transforming growth factor beta1 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1.


go_id: GO:0032912
term: negative regulation of transforming growth factor beta2 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2.


go_id: GO:0032913
term: negative regulation of transforming growth factor beta3 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3.


go_id: GO:0032914
term: positive regulation of transforming growth factor beta1 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.


go_id: GO:0032915
term: positive regulation of transforming growth factor beta2 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2.


go_id: GO:0032916
term: positive regulation of transforming growth factor beta3 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3.


go_id: GO:0032921
term: sarcosine oxidase complex
ontology: CC
definition:
A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity.


go_id: GO:0032922
term: circadian regulation of gene expression
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.


go_id: GO:0032923
term: organic phosphonate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.


go_id: GO:0032924
term: activin receptor signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0032925
term: regulation of activin receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway.


go_id: GO:0032926
term: negative regulation of activin receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.


go_id: GO:0032927
term: positive regulation of activin receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.


go_id: GO:0032928
term: regulation of superoxide anion generation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell.


go_id: GO:0032929
term: negative regulation of superoxide anion generation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell.


go_id: GO:0032930
term: positive regulation of superoxide anion generation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.


go_id: GO:0032931
term: histone acetyltransferase activity (H3-K56 specific)
ontology: MF
definition:
Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56).


go_id: GO:0032932
term: negative regulation of astral microtubule depolymerization
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules.


go_id: GO:0032933
term: SREBP signaling pathway
ontology: BP
definition:
A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.


go_id: GO:0032934
term: sterol binding
ontology: MF
definition:
Interacting selectively and non-covalently with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.


go_id: GO:0032935
term: sterol sensor activity
ontology: MF
definition:
Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of a sterol.


go_id: GO:0032936
term: SREBP-SCAP complex
ontology: CC
definition:
A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed.


go_id: GO:0032937
term: SREBP-SCAP-Insig complex
ontology: CC
definition:
A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane.


go_id: GO:0032938
term: negative regulation of translation in response to oxidative stress
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.


go_id: GO:0032939
term: positive regulation of translation in response to oxidative stress
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.


go_id: GO:0032942
term: inositol tetrakisphosphate 2-kinase activity
ontology: MF
definition:
Catalysis of the reaction: 1D-myo-inositol tetrakisphosphate + ATP = 1D-myo-inositol pentakisphosphate (containing 2-phosphate) + ADP.


go_id: GO:0032943
term: mononuclear cell proliferation
ontology: BP
definition:
The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form.


go_id: GO:0032945
term: negative regulation of mononuclear cell proliferation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation.


go_id: GO:0032946
term: positive regulation of mononuclear cell proliferation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.


go_id: GO:0032948
term: regulation of alpha-glucan metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans.


go_id: GO:0032949
term: regulation of alpha-glucan biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans.


go_id: GO:0032950
term: regulation of beta-glucan metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans.


go_id: GO:0032951
term: regulation of beta-glucan biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans.


go_id: GO:0032952
term: regulation of (1->3)-beta-D-glucan metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans.


go_id: GO:0032953
term: regulation of (1->3)-beta-D-glucan biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.


go_id: GO:0032955
term: regulation of barrier septum assembly
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of barrier septum formation. Barrier septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


go_id: GO:0032956
term: regulation of actin cytoskeleton organization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.


go_id: GO:0032957
term: inositol trisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.


go_id: GO:0032958
term: inositol phosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.


go_id: GO:0032959
term: inositol trisphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.


go_id: GO:0032960
term: regulation of inositol trisphosphate biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.


go_id: GO:0032961
term: negative regulation of inositol trisphosphate biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.


go_id: GO:0032962
term: positive regulation of inositol trisphosphate biosynthetic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.


go_id: GO:0032963
term: collagen metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).


go_id: GO:0032964
term: collagen biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).


go_id: GO:0032965
term: regulation of collagen biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.


go_id: GO:0032966
term: negative regulation of collagen biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.


go_id: GO:0032967
term: positive regulation of collagen biosynthetic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.


go_id: GO:0032968
term: positive regulation of transcription elongation from RNA polymerase II promoter
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.


go_id: GO:0032969
term: endosomal scaffold complex
ontology: CC
definition:
A protein complex that contains MAPKSP1 (MP1, Map2k1ip1) and ROBLD3 (p14, Mapbpip), is anchored to late endosomes, and is involved in selective activation of the ERK1 in ERK/MAPK signaling.


go_id: GO:0032970
term: regulation of actin filament-based process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.


go_id: GO:0032976
term: release of matrix enzymes from mitochondria
ontology: BP
definition:
The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process.


go_id: GO:0032977
term: membrane insertase activity
ontology: MF
definition:
Mediates the integration of proteins into a membrane from the inner side of the membrane. Membrane insertases are highly conserved and include the bacterial YidC family, the plant chloroplast Alb3 family, and the fungal and animal mitochondrial Oxa1/Cox18 family.


go_id: GO:0032978
term: protein insertion into membrane from inner side
ontology: BP
definition:
The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side.


go_id: GO:0032979
term: protein insertion into mitochondrial membrane from inner side
ontology: BP
definition:
The process in which a protein is incorporated into the mitochondrial membrane from the inner side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix.


go_id: GO:0032980
term: keratinocyte activation
ontology: BP
definition:
A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.


go_id: GO:0032981
term: mitochondrial respiratory chain complex I assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.


go_id: GO:0032982
term: myosin filament
ontology: CC
definition:
A protein complex containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament.


go_id: GO:0032983
term: kainate selective glutamate receptor complex
ontology: CC
definition:
An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluR5-7 and KA-1/2 subunits.


go_id: GO:0032989
term: cellular component morphogenesis
ontology: BP
definition:
The process in which cellular structures, including whole cells or cell parts, are generated and organized.


go_id: GO:0032991
term: macromolecular complex
ontology: CC
definition:
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.


go_id: GO:0032992
term: protein-carbohydrate complex
ontology: CC
definition:
A macromolecular complex containing separate protein and carbohydrate molecules.  Separate in this context means not covalently bound to each other.


go_id: GO:0032994
term: protein-lipid complex
ontology: CC
definition:
A macromolecular complex containing separate protein and lipid molecules.  Separate in this context means not covalently bound to each other.


go_id: GO:0032995
term: regulation of fungal-type cell wall biogenesis
ontology: BP
definition:
Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin.


go_id: GO:0032996
term: Bcl3-Bcl10 complex
ontology: CC
definition:
A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus.


go_id: GO:0032997
term: Fc receptor complex
ontology: CC
definition:
A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin.


go_id: GO:0032998
term: Fc-epsilon receptor I complex
ontology: CC
definition:
A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE.


go_id: GO:0032999
term: Fc-alpha receptor I complex
ontology: CC
definition:
A protein complex composed of an Fc-alpha R alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgA.


go_id: GO:0033000
term: Fc-gamma receptor I complex
ontology: CC
definition:
A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG.


go_id: GO:0033001
term: Fc-gamma receptor III complex
ontology: CC
definition:
A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG.


go_id: GO:0033004
term: negative regulation of mast cell activation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation.


go_id: GO:0033006
term: regulation of mast cell activation involved in immune response
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response.


go_id: GO:0033007
term: negative regulation of mast cell activation involved in immune response
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response.


go_id: GO:0033008
term: positive regulation of mast cell activation involved in immune response
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response.


go_id: GO:0033009
term: nucleomorph
ontology: CC
definition:
A small, vestigial nucleus found in some plastids that derive from a eukaryotic endosymbiont. Observed in chlorarachniophytes and cryptomonads, which acquired their plastids from a green and red alga respectively.


go_id: GO:0033010
term: paranodal junction
ontology: CC
definition:
A highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.


go_id: GO:0033011
term: perinuclear theca
ontology: CC
definition:
A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins.


go_id: GO:0033012
term: porosome
ontology: CC
definition:
A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles.


go_id: GO:0033013
term: tetrapyrrole metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.


go_id: GO:0033014
term: tetrapyrrole biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.


go_id: GO:0033015
term: tetrapyrrole catabolic process
ontology: BP
definition:
The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.


go_id: GO:0033023
term: mast cell homeostasis
ontology: BP
definition:
The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.


go_id: GO:0033024
term: mast cell apoptotic process
ontology: BP
definition:
Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.


go_id: GO:0033026
term: negative regulation of mast cell apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.


go_id: GO:0033027
term: positive regulation of mast cell apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process.


go_id: GO:0033028
term: myeloid cell apoptotic process
ontology: BP
definition:
Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.


go_id: GO:0033030
term: negative regulation of neutrophil apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.


go_id: GO:0033031
term: positive regulation of neutrophil apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process.


go_id: GO:0033033
term: negative regulation of myeloid cell apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.


go_id: GO:0033034
term: positive regulation of myeloid cell apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process.


go_id: GO:0033038
term: bitter taste receptor activity
ontology: MF
definition:
Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste.


go_id: GO:0033039
term: salty taste receptor activity
ontology: MF
definition:
Combining with soluble salty compounds to initiate a change in cell activity. These receptors are responsible for the sense of salty taste.


go_id: GO:0033040
term: sour taste receptor activity
ontology: MF
definition:
Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste.


go_id: GO:0033041
term: sweet taste receptor activity
ontology: MF
definition:
Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste.


go_id: GO:0033042
term: umami taste receptor activity
ontology: MF
definition:
Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates.


go_id: GO:0033043
term: regulation of organelle organization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.


go_id: GO:0033044
term: regulation of chromosome organization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.


go_id: GO:0033046
term: negative regulation of sister chromatid segregation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation.


go_id: GO:0033047
term: regulation of mitotic sister chromatid segregation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.


go_id: GO:0033048
term: negative regulation of mitotic sister chromatid segregation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis.


go_id: GO:0033049
term: clavulanic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.


go_id: GO:0033050
term: clavulanic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.


go_id: GO:0033051
term: aminophosphonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group.


go_id: GO:0033052
term: cyanoamino acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group.


go_id: GO:0033053
term: D-glutamine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid.


go_id: GO:0033054
term: D-glutamate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid.


go_id: GO:0033055
term: D-arginine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid.


go_id: GO:0033056
term: D-ornithine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid.


go_id: GO:0033057
term: multicellular organismal reproductive behavior
ontology: BP
definition:
The specific behavior of an organism that is associated with reproduction in a multicellular organism.


go_id: GO:0033060
term: ocellus pigmentation
ontology: BP
definition:
The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates.


go_id: GO:0033061
term: DNA recombinase mediator complex
ontology: CC
definition:
A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA.


go_id: GO:0033062
term: Rhp55-Rhp57 complex
ontology: CC
definition:
A conserved heterodimeric DNA recombinase mediator complex that contains the RecA family proteins Rhp55p and Rph57 in Schizosaccharomyces, or orthologs thereof (e.g. Rad55p and Rad57p in Saccharomyces).


go_id: GO:0033063
term: Rad51B-Rad51C-Rad51D-XRCC2 complex
ontology: CC
definition:
A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof.


go_id: GO:0033064
term: XRCC2-RAD51D complex
ontology: CC
definition:
A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or orthologs thereof; conserved from fission yeast to human but absent from budding yeast.


go_id: GO:0033065
term: Rad51C-XRCC3 complex
ontology: CC
definition:
A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof.


go_id: GO:0033066
term: Rad51B-Rad51C complex
ontology: CC
definition:
A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B and RAD51C, or orthologs thereof.


go_id: GO:0033067
term: macrolide metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.


go_id: GO:0033068
term: macrolide biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.


go_id: GO:0033069
term: ansamycin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.


go_id: GO:0033070
term: ansamycin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.


go_id: GO:0033071
term: vancomycin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.


go_id: GO:0033072
term: vancomycin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.


go_id: GO:0033073
term: pinene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.


go_id: GO:0033074
term: pinene catabolic process
ontology: BP
definition:
The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.


go_id: GO:0033075
term: isoquinoline alkaloid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.


go_id: GO:0033076
term: isoquinoline alkaloid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.


go_id: GO:0033077
term: T cell differentiation in thymus
ontology: BP
definition:
The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.


go_id: GO:0033078
term: extrathymic T cell differentiation
ontology: BP
definition:
The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.


go_id: GO:0033084
term: regulation of immature T cell proliferation in thymus
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus.


go_id: GO:0033085
term: negative regulation of T cell differentiation in thymus
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.


go_id: GO:0033086
term: negative regulation of extrathymic T cell differentiation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation.


go_id: GO:0033087
term: negative regulation of immature T cell proliferation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.


go_id: GO:0033088
term: negative regulation of immature T cell proliferation in thymus
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus.


go_id: GO:0033089
term: positive regulation of T cell differentiation in thymus
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus.


go_id: GO:0033090
term: positive regulation of extrathymic T cell differentiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation.


go_id: GO:0033091
term: positive regulation of immature T cell proliferation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of immature T cell proliferation.


go_id: GO:0033092
term: positive regulation of immature T cell proliferation in thymus
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus.


go_id: GO:0033093
term: Weibel-Palade body
ontology: CC
definition:
A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses.


go_id: GO:0033095
term: aleurone grain
ontology: CC
definition:
A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes.


go_id: GO:0033096
term: amyloplast envelope
ontology: CC
definition:
The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.


go_id: GO:0033098
term: amyloplast inner membrane
ontology: CC
definition:
The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma.


go_id: GO:0033099
term: attachment organelle
ontology: CC
definition:
A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division.


go_id: GO:0033100
term: NuA3 histone acetyltransferase complex
ontology: CC
definition:
A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p.


go_id: GO:0033103
term: protein secretion by the type VI secretion system
ontology: BP
definition:
The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.


go_id: GO:0033104
term: type VI protein secretion system complex
ontology: CC
definition:
A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence.


go_id: GO:0033105
term: chlorosome envelope
ontology: CC
definition:
The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome.


go_id: GO:0033107
term: CVT vesicle
ontology: CC
definition:
A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p).


go_id: GO:0033108
term: mitochondrial respiratory chain complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex.


go_id: GO:0033109
term: cortical actin cytoskeleton stabilization
ontology: BP
definition:
The process in which the assembly and arrangement of cytoskeletal structures in the actin cortex with respect to the plasma membrane is maintained.


go_id: GO:0033110
term: Cvt vesicle membrane
ontology: CC
definition:
Either of the two lipid bilayers surrounding a Cvt vesicle, a vesicle that functions in the cytoplasm-to-vacuole targeting (Cvt) pathway.


go_id: GO:0033111
term: attachment organelle membrane
ontology: CC
definition:
The lipid bilayer surrounding an attachment organelle.  This is a region of the cell membrane facing the environment - in mycoplasma, part of the mycolate outer membrane.


go_id: GO:0033112
term: cyanelle envelope
ontology: CC
definition:
The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space.


go_id: GO:0033116
term: endoplasmic reticulum-Golgi intermediate compartment membrane
ontology: CC
definition:
The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.


go_id: GO:0033118
term: esterosome membrane
ontology: CC
definition:
The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes.


go_id: GO:0033121
term: regulation of purine nucleotide catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.


go_id: GO:0033122
term: negative regulation of purine nucleotide catabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.


go_id: GO:0033123
term: positive regulation of purine nucleotide catabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.


go_id: GO:0033127
term: regulation of histone phosphorylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.


go_id: GO:0033128
term: negative regulation of histone phosphorylation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.


go_id: GO:0033129
term: positive regulation of histone phosphorylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.


go_id: GO:0033131
term: regulation of glucokinase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.


go_id: GO:0033132
term: negative regulation of glucokinase activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.


go_id: GO:0033133
term: positive regulation of glucokinase activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.


go_id: GO:0033134
term: ubiquitin activating enzyme binding
ontology: MF
definition:
Interacting selectively and non-covalently with a ubiquitin activating enzyme, any of the E1 proteins.


go_id: GO:0033137
term: negative regulation of peptidyl-serine phosphorylation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.


go_id: GO:0033138
term: positive regulation of peptidyl-serine phosphorylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.


go_id: GO:0033139
term: regulation of peptidyl-serine phosphorylation of STAT protein
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.


go_id: GO:0033140
term: negative regulation of peptidyl-serine phosphorylation of STAT protein
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.


go_id: GO:0033141
term: positive regulation of peptidyl-serine phosphorylation of STAT protein
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.


go_id: GO:0033143
term: regulation of intracellular steroid hormone receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.


go_id: GO:0033144
term: negative regulation of intracellular steroid hormone receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.


go_id: GO:0033145
term: positive regulation of intracellular steroid hormone receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.


go_id: GO:0033146
term: regulation of intracellular estrogen receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.


go_id: GO:0033147
term: negative regulation of intracellular estrogen receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.


go_id: GO:0033148
term: positive regulation of intracellular estrogen receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.


go_id: GO:0033149
term: FFAT motif binding
ontology: MF
definition:
Interacting selectively and non-covalently with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.


go_id: GO:0033150
term: cytoskeletal calyx
ontology: CC
definition:
A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins.


go_id: GO:0033151
term: V(D)J recombination
ontology: BP
definition:
The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).


go_id: GO:0033152
term: immunoglobulin V(D)J recombination
ontology: BP
definition:
The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.


go_id: GO:0033153
term: T cell receptor V(D)J recombination
ontology: BP
definition:
The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).


go_id: GO:0033154
term: oligogalacturonide transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in).


go_id: GO:0033156
term: oligogalacturonide transport
ontology: BP
definition:
The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033157
term: regulation of intracellular protein transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.


go_id: GO:0033158
term: regulation of protein import into nucleus, translocation
ontology: BP
definition:
Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.


go_id: GO:0033159
term: negative regulation of protein import into nucleus, translocation
ontology: BP
definition:
Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.


go_id: GO:0033160
term: positive regulation of protein import into nucleus, translocation
ontology: BP
definition:
Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.


go_id: GO:0033161
term: mitogen-activated protein kinase kinase kinase kinase binding
ontology: MF
definition:
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase kinase.


go_id: GO:0033164
term: glycolipid 6-alpha-mannosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.


go_id: GO:0033165
term: interphotoreceptor matrix
ontology: CC
definition:
A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance.


go_id: GO:0033166
term: hyaline layer
ontology: CC
definition:
A multilayered extraembryonic matrix that functions as a substrate for cell adhesion through early development. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. The major constituent of the hyaline layer is the protein hyalin. This matrix has been found in echinoderms.


go_id: GO:0033167
term: ARC complex
ontology: CC
definition:
A ribonucleoprotein complex that contains members of the Argonaute family of proteins, additional protein subunits, and duplex siRNA; required for heterochromatin assembly and siRNA generation. Possibly involved in the conversion of ds siRNA to ss siRNA.


go_id: GO:0033168
term: conversion of ds siRNA to ss siRNA involved in RNA interference
ontology: BP
definition:
The process in which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference.


go_id: GO:0033169
term: histone H3-K9 demethylation
ontology: BP
definition:
The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone.


go_id: GO:0033170
term: protein-DNA loading ATPase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the assembly of a protein or protein complex onto a DNA molecule.


go_id: GO:0033173
term: calcineurin-NFAT signaling cascade
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G-protein coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+).


go_id: GO:0033174
term: chloroplast proton-transporting ATP synthase complex, catalytic core CF(1)
ontology: CC
definition:
The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the chloroplast thylakoid membrane when the entire ATP synthase is assembled. The chloroplast F0 domain contains three alpha, three beta, one gamma, one delta, and one epsilon subunits.


go_id: GO:0033175
term: chloroplast proton-transporting ATP synthase complex, coupling factor CF(o)
ontology: CC
definition:
All non-F1 subunits of the chloroplast hydrogen-transporting ATP synthase, including integral and peripheral chloroplast thylakoid membrane proteins.


go_id: GO:0033176
term: proton-transporting V-type ATPase complex
ontology: CC
definition:
A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.


go_id: GO:0033177
term: proton-transporting two-sector ATPase complex, proton-transporting domain
ontology: CC
definition:
A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins.


go_id: GO:0033178
term: proton-transporting two-sector ATPase complex, catalytic domain
ontology: CC
definition:
A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled.


go_id: GO:0033179
term: proton-transporting V-type ATPase, V0 domain
ontology: CC
definition:
A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring.


go_id: GO:0033180
term: proton-transporting V-type ATPase, V1 domain
ontology: CC
definition:
A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A.


go_id: GO:0033182
term: regulation of histone ubiquitination
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.


go_id: GO:0033183
term: negative regulation of histone ubiquitination
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.


go_id: GO:0033184
term: positive regulation of histone ubiquitination
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.


go_id: GO:0033185
term: dolichol-phosphate-mannose synthase complex
ontology: CC
definition:
A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively.


go_id: GO:0033186
term: CAF-1 complex
ontology: CC
definition:
A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48.


go_id: GO:0033188
term: sphingomyelin synthase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin.


go_id: GO:0033189
term: response to vitamin A
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.


go_id: GO:0033192
term: calmodulin-dependent protein phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.


go_id: GO:0033193
term: Lsd1/2 complex
ontology: CC
definition:
A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast.


go_id: GO:0033194
term: response to hydroperoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.


go_id: GO:0033195
term: response to alkyl hydroperoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.


go_id: GO:0033197
term: response to vitamin E
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.


go_id: GO:0033198
term: response to ATP
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.


go_id: GO:0033200
term: inositol heptakisphosphate 5-kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.


go_id: GO:0033201
term: alpha-1,4-glucan synthase activity
ontology: MF
definition:
Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP.


go_id: GO:0033203
term: DNA helicase A complex
ontology: CC
definition:
A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction.


go_id: GO:0033206
term: meiotic cytokinesis
ontology: BP
definition:
A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells.


go_id: GO:0033207
term: beta-1,4-N-acetylgalactosaminyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming a beta-1,4 linkage.


go_id: GO:0033208
ontology: MF
term:
UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity

definition:
Catalysis of the reaction: UDP-N-acetylgalactosamine + N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide = UDP + N-acetylgalactosaminyl-N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide.


go_id: GO:0033209
term: tumor necrosis factor-mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0033210
term: leptin-mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.


go_id: GO:0033211
term: adiponectin-activated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0033213
term: iron assimilation by capture and transport
ontology: BP
definition:
A process in which iron (Fe3+) is solubilized by binding to a receptor or transport protein and transported into a cell.


go_id: GO:0033214
term: iron assimilation by chelation and transport
ontology: BP
definition:
A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors.


go_id: GO:0033215
term: iron assimilation by reduction and transport
ontology: BP
definition:
A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins.


go_id: GO:0033217
term: regulation of transcription from RNA polymerase II promoter in response to iron ion starvation
ontology: BP
definition:
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.


go_id: GO:0033218
term: amide binding
ontology: MF
definition:
Interacting selectively and non-covalently with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.


go_id: GO:0033219
term: urea binding
ontology: MF
definition:
Interacting selectively and non-covalently with urea, a water-soluble carboxamide with the structure H2N-CO-NH2.


go_id: GO:0033223
term: 2-aminoethylphosphonate transport
ontology: BP
definition:
The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033224
term: 2-aminoethylphosphonate transmembrane transporter activity
ontology: MF
definition:
Enables the directed movement of 2-aminoethylphosphonate into, out of or within a cell, or between cells.


go_id: GO:0033225
term: 2-aminoethylphosphonate transporting ATPase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in).


go_id: GO:0033227
term: dsRNA transport
ontology: BP
definition:
The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033230
term: cysteine-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out).


go_id: GO:0033232
term: D-methionine-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out).


go_id: GO:0033233
term: regulation of protein sumoylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein.


go_id: GO:0033234
term: negative regulation of protein sumoylation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.


go_id: GO:0033235
term: positive regulation of protein sumoylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.


go_id: GO:0033238
term: regulation of cellular amine metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.


go_id: GO:0033239
term: negative regulation of cellular amine metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.


go_id: GO:0033240
term: positive regulation of cellular amine metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.


go_id: GO:0033241
term: regulation of cellular amine catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


go_id: GO:0033242
term: negative regulation of cellular amine catabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


go_id: GO:0033243
term: positive regulation of cellular amine catabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


go_id: GO:0033244
term: regulation of penicillin metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033245
term: negative regulation of penicillin metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033246
term: positive regulation of penicillin metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033247
term: regulation of penicillin catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033248
term: negative regulation of penicillin catabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033249
term: positive regulation of penicillin catabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.


go_id: GO:0033250
term: penicillinase activity
ontology: MF
definition:
Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin.


go_id: GO:0033251
term: cephalosporinase activity
ontology: MF
definition:
Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin.


go_id: GO:0033252
term: regulation of beta-lactamase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid.


go_id: GO:0033253
term: regulation of penicillinase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative.


go_id: GO:0033254
term: vacuolar transporter chaperone complex
ontology: CC
definition:
A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p.


go_id: GO:0033255
term: SAS acetyltransferase complex
ontology: CC
definition:
A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p.


go_id: GO:0033256
term: I-kappaB/NF-kappaB complex
ontology: CC
definition:
A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm.


go_id: GO:0033257
term: Bcl3/NF-kappaB2 complex
ontology: CC
definition:
A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.


go_id: GO:0033260
term: nuclear DNA replication
ontology: BP
definition:
The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.


go_id: GO:0033262
term: regulation of nuclear cell cycle DNA replication
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.


go_id: GO:0033263
term: CORVET complex
ontology: CC
definition:
A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.


go_id: GO:0033265
term: choline binding
ontology: MF
definition:
Interacting selectively and non-covalently with choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.


go_id: GO:0033266
term: choline-transporting ATPase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.


go_id: GO:0033268
term: node of Ranvier
ontology: CC
definition:
An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed.


go_id: GO:0033270
term: paranode region of axon
ontology: CC
definition:
An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.


go_id: GO:0033271
term: myo-inositol phosphate transport
ontology: BP
definition:
The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033272
term: myo-inositol hexakisphosphate transport
ontology: BP
definition:
The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033273
term: response to vitamin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.


go_id: GO:0033274
term: response to vitamin B2
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.


go_id: GO:0033276
term: transcription factor TFTC complex
ontology: CC
definition:
A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity.


go_id: GO:0033277
term: abortive mitotic cell cycle
ontology: BP
definition:
A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy.


go_id: GO:0033278
term: cell proliferation in midbrain
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.


go_id: GO:0033280
term: response to vitamin D
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.


go_id: GO:0033281
term: TAT protein transport complex
ontology: CC
definition:
A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins.


go_id: GO:0033282
term: protein C inhibitor-acrosin complex
ontology: CC
definition:
A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin.


go_id: GO:0033283
term: organic acid-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out).


go_id: GO:0033284
term: carboxylic acid-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).


go_id: GO:0033285
term: monocarboxylic acid-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out).


go_id: GO:0033286
term: ectoine-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out).


go_id: GO:0033288
term: hydroxyectoine-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out).


go_id: GO:0033290
term: eukaryotic 48S preinitiation complex
ontology: CC
definition:
A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA.


go_id: GO:0033291
term: eukaryotic 80S initiation complex
ontology: CC
definition:
A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.


go_id: GO:0033292
term: T-tubule organization
ontology: BP
definition:
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.


go_id: GO:0033293
term: monocarboxylic acid binding
ontology: MF
definition:
Interacting selectively and non-covalently with a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-).


go_id: GO:0033294
term: ectoine binding
ontology: MF
definition:
Interacting selectively and non-covalently with ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid.


go_id: GO:0033297
term: rhamnose-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + rhamnose(out/in) = ADP + phosphate + rhamnose(in/out).


go_id: GO:0033298
term: contractile vacuole organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores.


go_id: GO:0033300
term: dehydroascorbic acid transporter activity
ontology: MF
definition:
Enables the directed movement of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033301
term: cell cycle comprising mitosis without cytokinesis
ontology: BP
definition:
A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N).


go_id: GO:0033303
term: quercetin O-glucoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin.


go_id: GO:0033306
term: phytol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.


go_id: GO:0033307
term: phytol salvage
ontology: BP
definition:
A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis.


go_id: GO:0033308
term: hydroxyectoine transport
ontology: BP
definition:
The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033309
term: SBF transcription complex
ontology: CC
definition:
A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi6p and the activator Swi4p, and is associated with additional proteins known as Whi5p and Msa1p.


go_id: GO:0033311
term: chlorophyll a biosynthetic process via phytyl diphosphate
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate.


go_id: GO:0033312
term: chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a.


go_id: GO:0033313
term: meiotic cell cycle checkpoint
ontology: BP
definition:
A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage.


go_id: GO:0033314
term: mitotic DNA replication checkpoint
ontology: BP
definition:
A cell cycle checkpoint that acts during a mitotic cell cycle and prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.


go_id: GO:0033315
term: meiotic DNA replication checkpoint
ontology: BP
definition:
A cell cycle checkpoint that acts during a meiotic cell cycle and prevents the initiation of cell division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the haploid genome.


go_id: GO:0033316
term: meiotic spindle assembly checkpoint
ontology: BP
definition:
A cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle.


go_id: GO:0033317
term: pantothenate biosynthetic process from valine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid, from other compounds, including valine.


go_id: GO:0033318
term: pantothenate biosynthetic process from 2-dehydropantolactone
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid, from other compounds, including 2-dehydropantolactone.


go_id: GO:0033319
term: UDP-D-xylose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033320
term: UDP-D-xylose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033321
term: homomethionine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.


go_id: GO:0033322
term: homomethionine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.


go_id: GO:0033323
term: choline biosynthetic process via CDP-choline
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline.


go_id: GO:0033324
term: choline biosynthetic process via N-monomethylethanolamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine.


go_id: GO:0033325
term: choline biosynthetic process via phosphoryl-ethanolamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine.


go_id: GO:0033326
term: cerebrospinal fluid secretion
ontology: BP
definition:
The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces.


go_id: GO:0033327
term: Leydig cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.


go_id: GO:0033328
term: peroxisome membrane targeting sequence binding
ontology: MF
definition:
Interacting selectively and non-covalently with a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane.


go_id: GO:0033330
term: kaempferol O-glucoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol.


go_id: GO:0033331
term: ent-kaurene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.


go_id: GO:0033332
term: ent-kaurene biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.


go_id: GO:0033333
term: fin development
ontology: BP
definition:
The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.


go_id: GO:0033335
term: anal fin development
ontology: BP
definition:
The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure.


go_id: GO:0033336
term: caudal fin development
ontology: BP
definition:
The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure.


go_id: GO:0033337
term: dorsal fin development
ontology: BP
definition:
The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure.


go_id: GO:0033338
term: medial fin development
ontology: BP
definition:
The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure.


go_id: GO:0033339
term: pectoral fin development
ontology: BP
definition:
The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.


go_id: GO:0033340
term: pelvic fin development
ontology: BP
definition:
The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure.


go_id: GO:0033345
term: asparagine catabolic process via L-aspartate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.


go_id: GO:0033346
term: asparagine catabolic process via 2-oxosuccinamate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate.


go_id: GO:0033347
term: tetrose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.


go_id: GO:0033348
term: tetrose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.


go_id: GO:0033349
term: apiose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.


go_id: GO:0033350
term: apiose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.


go_id: GO:0033351
term: UDP-D-apiose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033352
term: UDP-D-apiose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033353
term: S-adenosylmethionine cycle
ontology: BP
definition:
A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine.


go_id: GO:0033354
term: chlorophyll cycle
ontology: BP
definition:
A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates.


go_id: GO:0033355
term: ascorbate glutathione cycle
ontology: BP
definition:
A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH.


go_id: GO:0033356
term: UDP-L-arabinose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033358
term: UDP-L-arabinose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033359
term: lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.


go_id: GO:0033360
term: lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.


go_id: GO:0033361
term: lysine biosynthetic process via diaminopimelate, dehydrogenase pathway
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step.


go_id: GO:0033362
term: lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps.


go_id: GO:0033363
term: secretory granule organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.


go_id: GO:0033364
term: mast cell secretory granule organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.


go_id: GO:0033366
term: protein localization to secretory granule
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within a secretory granule.


go_id: GO:0033367
term: protein localization to mast cell secretory granule
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell.


go_id: GO:0033368
term: protease localization to mast cell secretory granule
ontology: BP
definition:
Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.


go_id: GO:0033370
term: maintenance of protein location in mast cell secretory granule
ontology: BP
definition:
A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.


go_id: GO:0033371
term: T cell secretory granule organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.


go_id: GO:0033373
term: maintenance of protease location in mast cell secretory granule
ontology: BP
definition:
A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.


go_id: GO:0033374
term: protein localization to T cell secretory granule
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell.


go_id: GO:0033375
term: protease localization to T cell secretory granule
ontology: BP
definition:
Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell.


go_id: GO:0033377
term: maintenance of protein location in T cell secretory granule
ontology: BP
definition:
A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere.


go_id: GO:0033379
term: maintenance of protease location in T cell secretory granule
ontology: BP
definition:
A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere.


go_id: GO:0033380
term: granzyme B localization to T cell secretory granule
ontology: BP
definition:
Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.


go_id: GO:0033381
term: establishment of granzyme B localization to T cell secretory granule
ontology: BP
definition:
The directed movement of the protease granzyme B to a location within a secretory granule in a T cell.


go_id: GO:0033382
term: maintenance of granzyme B location in T cell secretory granule
ontology: BP
definition:
A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere.


go_id: GO:0033383
term: geranyl diphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.


go_id: GO:0033385
term: geranylgeranyl diphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins.


go_id: GO:0033387
term: putrescine biosynthetic process from ornithine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine.


go_id: GO:0033388
term: putrescine biosynthetic process from arginine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine.


go_id: GO:0033389
term: putrescine biosynthetic process from arginine, using agmatinase
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step.


go_id: GO:0033390
term: putrescine biosynthetic process from arginine via N-carbamoylputrescine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps.


go_id: GO:0033391
term: chromatoid body
ontology: CC
definition:
A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).


go_id: GO:0033393
term: homogalacturonan catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.


go_id: GO:0033394
term: beta-alanine biosynthetic process via 1,3 diaminopropane
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane.


go_id: GO:0033395
term: beta-alanine biosynthetic process via 3-hydroxypropionate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate.


go_id: GO:0033396
term: beta-alanine biosynthetic process via 3-ureidopropionate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate.


go_id: GO:0033398
term: zeatin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


go_id: GO:0033399
term: cis-zeatin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


go_id: GO:0033400
term: trans-zeatin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


go_id: GO:0033465
term: cis-zeatin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


go_id: GO:0033466
term: trans-zeatin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


go_id: GO:0033467
term: CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.


go_id: GO:0033468
term: CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.


go_id: GO:0033469
term: gibberellin 12 metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.


go_id: GO:0033470
term: gibberellin 12 biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.


go_id: GO:0033471
term: GDP-L-galactose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.


go_id: GO:0033472
term: GDP-L-galactose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.


go_id: GO:0033473
term: indoleacetic acid conjugate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.


go_id: GO:0033474
term: indoleacetic acid conjugate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.


go_id: GO:0033475
term: indoleacetic acid amide conjugate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond.


go_id: GO:0033476
term: indoleacetic acid ester conjugate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond.


go_id: GO:0033477
term: S-methylmethionine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.


go_id: GO:0033478
term: UDP-rhamnose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.


go_id: GO:0033479
term: UDP-D-galacturonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.


go_id: GO:0033480
term: UDP-D-galacturonate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.


go_id: GO:0033481
term: galacturonate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid.


go_id: GO:0033482
term: D-galacturonate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.


go_id: GO:0033483
term: gas homeostasis
ontology: BP
definition:
A homeostatic process involved in the maintenance of an internal steady state of a gas within an organism or cell.


go_id: GO:0033484
term: nitric oxide homeostasis
ontology: BP
definition:
A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell.


go_id: GO:0033485
term: cyanidin 3-O-glucoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.


go_id: GO:0033486
term: delphinidin 3-O-glucoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits.


go_id: GO:0033487
term: pelargonidin 3-O-glucoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.


go_id: GO:0033488
term: cholesterol biosynthetic process via 24,25-dihydrolanosterol
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol.


go_id: GO:0033489
term: cholesterol biosynthetic process via desmosterol
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol.


go_id: GO:0033490
term: cholesterol biosynthetic process via lathosterol
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.


go_id: GO:0033491
term: coniferin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside.


go_id: GO:0033494
term: ferulate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.


go_id: GO:0033495
term: ferulate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.


go_id: GO:0033496
term: sinapate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


go_id: GO:0033497
term: sinapate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


go_id: GO:0033498
term: galactose catabolic process via D-galactonate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate.


go_id: GO:0033499
term: galactose catabolic process via UDP-galactose
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.


go_id: GO:0033500
term: carbohydrate homeostasis
ontology: BP
definition:
A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.


go_id: GO:0033501
term: galactose homeostasis
ontology: BP
definition:
A homeostatic process involved in the maintenance of an internal steady state of galactose within an organism or cell.


go_id: GO:0033502
term: cellular galactose homeostasis
ontology: BP
definition:
A cellular homeostatic process involved in the maintenance of an internal steady state of galactose within a cell or between a cell and its external environment.


go_id: GO:0033503
term: HULC complex
ontology: CC
definition:
A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2.


go_id: GO:0033506
term: glucosinolate biosynthetic process from homomethionine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine.


go_id: GO:0033507
term: glucosinolate biosynthetic process from phenylalanine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine.


go_id: GO:0033508
term: glutamate catabolic process to butyrate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate.


go_id: GO:0033509
term: glutamate catabolic process to propionate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate.


go_id: GO:0033510
term: luteolin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.


go_id: GO:0033511
term: luteolin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.


go_id: GO:0033512
term: L-lysine catabolic process to acetyl-CoA via saccharopine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine.


go_id: GO:0033513
term: L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide.


go_id: GO:0033514
term: L-lysine catabolic process to acetyl-CoA via L-pipecolate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate.


go_id: GO:0033515
term: L-lysine catabolic process using lysine 6-aminotransferase
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase.


go_id: GO:0033516
term: L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine.


go_id: GO:0033517
term: myo-inositol hexakisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.


go_id: GO:0033519
term: phytyl diphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.


go_id: GO:0033520
term: phytol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.


go_id: GO:0033521
term: phytyl diphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.


go_id: GO:0033524
term: sinapate ester metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


go_id: GO:0033525
term: sinapate ester biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


go_id: GO:0033526
term: tetrapyrrole biosynthetic process from glutamate
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate.


go_id: GO:0033527
term: tetrapyrrole biosynthetic process from glycine and succinyl-CoA
ontology: BP
definition:
The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA.


go_id: GO:0033528
term: S-methylmethionine cycle
ontology: BP
definition:
A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level.


go_id: GO:0033529
term: raffinose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033530
term: raffinose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033531
term: stachyose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033532
term: stachyose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033533
term: verbascose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033534
term: verbascose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033535
term: ajugose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033536
term: ajugose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0033537
term: ajugose biosynthetic process using galactinol:raffinose galactosyltransferase
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide.


go_id: GO:0033538
term: ajugose biosynthetic process using galactan:galactan galactosyltransferase
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another.


go_id: GO:0033539
term: fatty acid beta-oxidation using acyl-CoA dehydrogenase
ontology: BP
definition:
A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033540
term: fatty acid beta-oxidation using acyl-CoA oxidase
ontology: BP
definition:
A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033541
term: fatty acid beta-oxidation, unsaturated, odd number
ontology: BP
definition:
A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033542
term: fatty acid beta-oxidation, unsaturated, even number
ontology: BP
definition:
A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033543
term: fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway
ontology: BP
definition:
A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033544
term: fatty acid beta-oxidation, unsaturated, even number, epimerase pathway
ontology: BP
definition:
A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


go_id: GO:0033545
term: myo-inositol hexakisphosphate biosynthetic process, lipid-dependent
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C.


go_id: GO:0033546
term: myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further.


go_id: GO:0033548
term: myo-inositol hexakisphosphate biosynthetic process, lipid-independent
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate.


go_id: GO:0033551
term: monopolin complex
ontology: CC
definition:
A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits.


go_id: GO:0033552
term: response to vitamin B3
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.


go_id: GO:0033555
term: multicellular organismal response to stress
ontology: BP
definition:
Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


go_id: GO:0033556
term: dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the addition of a glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol.


go_id: GO:0033557
term: Slx1-Slx4 complex
ontology: CC
definition:
A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes.


go_id: GO:0033559
term: unsaturated fatty acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.


go_id: GO:0033562
term: co-transcriptional gene silencing by RNA interference machinery
ontology: BP
definition:
A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin.


go_id: GO:0033563
term: dorsal/ventral axon guidance
ontology: BP
definition:
The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.


go_id: GO:0033564
term: anterior/posterior axon guidance
ontology: BP
definition:
The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.


go_id: GO:0033565
term: ESCRT-0 complex
ontology: CC
definition:
A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals.


go_id: GO:0033566
term: gamma-tubulin complex localization
ontology: BP
definition:
Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.


go_id: GO:0033567
term: DNA replication, Okazaki fragment processing
ontology: BP
definition:
The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand.


go_id: GO:0033568
term: lactoferrin receptor activity
ontology: MF
definition:
Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH.


go_id: GO:0033571
term: lactoferrin transport
ontology: BP
definition:
The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033572
term: transferrin transport
ontology: BP
definition:
The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0033573
term: high-affinity iron permease complex
ontology: CC
definition:
A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


go_id: GO:0033574
term: response to testosterone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.


go_id: GO:0033575
term: protein glycosylation at cell surface
ontology: BP
definition:
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid at the surface of a cell.


go_id: GO:0033576
term: protein glycosylation in cytosol
ontology: BP
definition:
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol.


go_id: GO:0033577
term: protein glycosylation in endoplasmic reticulum
ontology: BP
definition:
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum.


go_id: GO:0033578
term: protein glycosylation in Golgi
ontology: BP
definition:
The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.


go_id: GO:0033584
term: tyrosine biosynthetic process from chorismate via L-arogenate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate.


go_id: GO:0033585
term: L-phenylalanine biosynthetic process from chorismate via phenylpyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate.


go_id: GO:0033586
term: L-phenylalanine biosynthetic process from chorismate via L-arogenate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate.


go_id: GO:0033587
term: shikimate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.


go_id: GO:0033588
term: Elongator holoenzyme complex
ontology: CC
definition:
A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes.


go_id: GO:0033590
term: response to cobalamin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.


go_id: GO:0033591
term: response to L-ascorbic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.


go_id: GO:0033593
term: BRCA2-MAGE-D1 complex
ontology: CC
definition:
A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth.


go_id: GO:0033594
term: response to hydroxyisoflavone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.


go_id: GO:0033595
term: response to genistein
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.


go_id: GO:0033596
term: TSC1-TSC2 complex
ontology: CC
definition:
A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.


go_id: GO:0033597
term: mitotic checkpoint complex
ontology: CC
definition:
A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.


go_id: GO:0033598
term: mammary gland epithelial cell proliferation
ontology: BP
definition:
The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.


go_id: GO:0033599
term: regulation of mammary gland epithelial cell proliferation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.


go_id: GO:0033600
term: negative regulation of mammary gland epithelial cell proliferation
ontology: BP
definition:
Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation.


go_id: GO:0033601
term: positive regulation of mammary gland epithelial cell proliferation
ontology: BP
definition:
Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation.


go_id: GO:0033602
term: negative regulation of dopamine secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.


go_id: GO:0033603
term: positive regulation of dopamine secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.


go_id: GO:0033604
term: negative regulation of catecholamine secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.


go_id: GO:0033605
term: positive regulation of catecholamine secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine.


go_id: GO:0033607
term: SOD1-Bcl-2 complex
ontology: CC
definition:
A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway.


go_id: GO:0033610
term: oxalate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate.


go_id: GO:0033611
term: oxalate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.


go_id: GO:0033612
term: receptor serine/threonine kinase binding
ontology: MF
definition:
Interacting selectively and non-covalently with a receptor that possesses protein serine/threonine kinase activity.


go_id: GO:0033613
term: activating transcription factor binding
ontology: MF
definition:
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.


go_id: GO:0033614
term: chloroplast proton-transporting ATP synthase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane.


go_id: GO:0033615
term: mitochondrial proton-transporting ATP synthase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.


go_id: GO:0033616
term: plasma membrane proton-transporting ATP synthase complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane.


go_id: GO:0033617
term: mitochondrial respiratory chain complex IV assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.


go_id: GO:0033618
term: plasma membrane respiratory chain complex IV assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane.


go_id: GO:0033619
term: membrane protein proteolysis
ontology: BP
definition:
The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.


go_id: GO:0033620
term: Mei2 nuclear dot complex
ontology: CC
definition:
A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I.


go_id: GO:0033621
term: nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
ontology: BP
definition:
The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.


go_id: GO:0033622
term: integrin activation
ontology: BP
definition:
The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.


go_id: GO:0033626
term: positive regulation of integrin activation by cell surface receptor linked signal transduction
ontology: BP
definition:
Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell that lead to the increased affinity of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, for its extracellular ligands.


go_id: GO:0033627
term: cell adhesion mediated by integrin
ontology: BP
definition:
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.


go_id: GO:0033629
term: negative regulation of cell adhesion mediated by integrin
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.


go_id: GO:0033630
term: positive regulation of cell adhesion mediated by integrin
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.


go_id: GO:0033631
term: cell-cell adhesion mediated by integrin
ontology: BP
definition:
The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.


go_id: GO:0033632
term: regulation of cell-cell adhesion mediated by integrin
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.


go_id: GO:0033633
term: negative regulation of cell-cell adhesion mediated by integrin
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.


go_id: GO:0033634
term: positive regulation of cell-cell adhesion mediated by integrin
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin.


go_id: GO:0033635
term: modulation by symbiont of host response to abiotic stimulus
ontology: BP
definition:
Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033636
term: modulation by symbiont of host response to temperature stimulus
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033637
term: modulation by symbiont of host response to cold
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033638
term: modulation by symbiont of host response to heat
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033639
term: modulation by symbiont of host response to water
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033640
term: modulation by symbiont of host response to osmotic stress
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033641
term: modulation by symbiont of host response to pH
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033642
term: modulation by symbiont of host response to gravitational stimulus
ontology: BP
definition:
Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033643
term: host cell part
ontology: CC
definition:
Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033644
term: host cell membrane
ontology: CC
definition:
Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033645
term: host cell endomembrane system
ontology: CC
definition:
A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033646
term: host intracellular part
ontology: CC
definition:
Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033647
term: host intracellular organelle
ontology: CC
definition:
Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033648
term: host intracellular membrane-bounded organelle
ontology: CC
definition:
Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033650
term: host cell mitochondrion
ontology: CC
definition:
A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033651
term: host cell plastid
ontology: CC
definition:
Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033652
term: host cell chloroplast
ontology: CC
definition:
A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033653
term: host cell chloroplast part
ontology: CC
definition:
Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033654
term: host cell chloroplast thylakoid membrane
ontology: CC
definition:
Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033655
term: host cell cytoplasm part
ontology: CC
definition:
Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033656
term: modification by symbiont of host chloroplast
ontology: BP
definition:
The process in which an organism effects a change in the structure or function of host cell chloroplasts. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033657
term: modification by symbiont of host chloroplast part
ontology: BP
definition:
The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033658
term: modification by symbiont of host chloroplast thylakoid
ontology: BP
definition:
The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033659
term: modification by symbiont of host mitochondrion
ontology: BP
definition:
The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033660
term: negative regulation by symbiont of host resistance gene-dependent defense response
ontology: BP
definition:
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033661
term: negative regulation by symbiont of defense-related host reactive oxygen species production
ontology: BP
definition:
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033662
term: modulation by symbiont of host defense-related protein level
ontology: BP
definition:
The alternation by a symbiont of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033663
term: negative regulation by symbiont of host defense-related protein level
ontology: BP
definition:
Any process in which the symbiont stops or reduces of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033664
term: positive regulation by symbiont of host defense-related protein level
ontology: BP
definition:
Any process in which the symbiont activates, maintains or increases levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0044126
term: regulation of growth of symbiont in host
ontology: BP
definition:
Any process in which the symbiont regulates the increase in its size or mass within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.


go_id: GO:0044127
term: regulation of development of symbiont in host
ontology: BP
definition:
Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.


go_id: GO:0044128
term: positive regulation of growth of symbiont in host
ontology: BP
definition:
Any process in which the symbiont activates, maintains or increases its size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.


go_id: GO:0044129
term: positive regulation of development of symbiont in host
ontology: BP
definition:
Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.


go_id: GO:0044130
term: negative regulation of growth of symbiont in host
ontology: BP
definition:
Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.


go_id: GO:0044131
term: negative regulation of development of symbiont in host
ontology: BP
definition:
Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.


go_id: GO:0033668
term: negative regulation by symbiont of host apoptotic process
ontology: BP
definition:
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0033670
term: regulation of NAD+ kinase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.


go_id: GO:0033671
term: negative regulation of NAD+ kinase activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.


go_id: GO:0033672
term: positive regulation of NAD+ kinase activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.


go_id: GO:0033673
term: negative regulation of kinase activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.


go_id: GO:0033674
term: positive regulation of kinase activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.


go_id: GO:0033675
term: pericanalicular vesicle
ontology: CC
definition:
A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes.


go_id: GO:0033676
term: double-stranded DNA-dependent ATPase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of double-stranded DNA, and it drives another reaction.


go_id: GO:0033677
term: DNA/RNA helicase activity
ontology: MF
definition:
Catalysis of the reaction: NTP + H2O = NDP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA.


go_id: GO:0033680
term: ATP-dependent DNA/RNA helicase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex.


go_id: GO:0033681
term: ATP-dependent 3'-5' DNA/RNA helicase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 3' to 5'.


go_id: GO:0033682
term: ATP-dependent 5'-3' DNA/RNA helicase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 5' to 3'.


go_id: GO:0033683
term: nucleotide-excision repair, DNA incision
ontology: BP
definition:
A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound.


go_id: GO:0033684
term: regulation of luteinizing hormone secretion
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone.


go_id: GO:0033685
term: negative regulation of luteinizing hormone secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.


go_id: GO:0033686
term: positive regulation of luteinizing hormone secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.


go_id: GO:0033687
term: osteoblast proliferation
ontology: BP
definition:
The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.


go_id: GO:0033691
term: sialic acid binding
ontology: MF
definition:
Interacting selectively and non-covalently with sialic acid, any of a variety of N- or O- substituted derivatives of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.


go_id: GO:0033692
term: cellular polysaccharide biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell.


go_id: GO:0033693
term: neurofilament bundle assembly
ontology: BP
definition:
The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules.


go_id: GO:0033694
term: oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor
ontology: MF
definition:
Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.


go_id: GO:0033695
term: oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
ontology: MF
definition:
Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule.


go_id: GO:0033696
term: negative regulation of extent of heterochromatin assembly
ontology: BP
definition:
Any process that reduces the extent of heterochromatin formation; reduces the size of a chromosomal region converted to heterochromatin.


go_id: GO:0033697
term: positive regulation of extent of heterochromatin assembly
ontology: BP
definition:
Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin.


go_id: GO:0033698
term: Rpd3L complex
ontology: CC
definition:
A histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae).


go_id: GO:0033699
term: DNA 5'-adenosine monophosphate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.


go_id: GO:0033701
term: dTDP-galactose 6-dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+.


go_id: GO:0033703
term: 3beta-hydroxy-5beta-steroid dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH.


go_id: GO:0033704
term: 3beta-hydroxy-5alpha-steroid dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + H(+) + NADPH.


go_id: GO:0033705
term: GDP-4-dehydro-6-deoxy-D-mannose reductase activity
ontology: MF
definition:
Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+.


go_id: GO:0033707
term: 3''-deamino-3''-oxonicotianamine reductase activity
ontology: MF
definition:
Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+.


go_id: GO:0033708
term: isocitrate-homoisocitrate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+.


go_id: GO:0033711
term: 4-phosphoerythronate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H(+) + NADH.


go_id: GO:0033712
term: 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity
ontology: MF
definition:
Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH.


go_id: GO:0033715
term: nucleoside oxidase activity
ontology: MF
definition:
Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O.


go_id: GO:0033716
term: nucleoside oxidase (hydrogen peroxide-forming) activity
ontology: MF
definition:
Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide; (1a) adenosine + O2 = 5'-dehydroadenosine + hydrogen peroxide, and (1b) 5'-dehydroadenosine + O2 = 9-riburonosyladenine + hydrogen peroxide.


go_id: GO:0033718
term: pyranose dehydrogenase (acceptor) activity
ontology: MF
definition:
Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor.


go_id: GO:0033719
term: 2-oxo-acid reductase activity
ontology: MF
definition:
Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor.


go_id: GO:0033720
term: (S)-mandelate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor.


go_id: GO:0033726
term: aldehyde ferredoxin oxidoreductase activity
ontology: MF
definition:
Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin.


go_id: GO:0033732
term: pyrroloquinoline-quinone synthase activity
ontology: MF
definition:
Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 2 H(2)O + 2 H(2)O(2) + H(+) + pyrroloquinoline quinone.


go_id: GO:0033734
term: (R)-benzylsuccinyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein.


go_id: GO:0033739
term: preQ1 synthase activity
ontology: MF
definition:
Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH.


go_id: GO:0033740
term: hydroxylamine oxidoreductase activity
ontology: MF
definition:
Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O, and hydrazine + acceptor = N2 + reduced acceptor.


go_id: GO:0033741
term: adenylyl-sulfate reductase (glutathione) activity
ontology: MF
definition:
Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.


go_id: GO:0033743
term: peptide-methionine (R)-S-oxide reductase activity
ontology: MF
definition:
Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.


go_id: GO:0033744
term: L-methionine:thioredoxin-disulfide S-oxidoreductase activity
ontology: MF
definition:
Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin.


go_id: GO:0033745
term: L-methionine-(R)-S-oxide reductase activity
ontology: MF
definition:
Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin.


go_id: GO:0052750
term: reactive-black-5:hydrogen-peroxide oxidoreductase activity
ontology: MF
definition:
Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O.


go_id: GO:0033754
term: indoleamine 2,3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine.


go_id: GO:0033757
term: glucoside 3-dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor.


go_id: GO:0033758
term: clavaminate synthase activity
ontology: MF
definition:
Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O.


go_id: GO:0033760
term: 2'-deoxymugineic-acid 2'-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O(2) = CO(2) + H(+) + mugineate + succinate.


go_id: GO:0033761
term: mugineic-acid 3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2.


go_id: GO:0033762
term: response to glucagon
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.


go_id: GO:0033763
term: proline 3-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2.


go_id: GO:0033764
term: steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
ontology: MF
definition:
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.


go_id: GO:0033765
term: steroid dehydrogenase activity, acting on the CH-CH group of donors
ontology: MF
definition:
Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative.


go_id: GO:0033766
term: 2-hydroxyquinoline 8-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-2-ol = H(2)O + NAD(+) + quinoline-2,8-diol.


go_id: GO:0033767
term: 4-hydroxyacetophenone monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4'-hydroxyacetophenone + H(+) + NADPH + O(2) = 4-hydroxyphenyl acetate + H(2)O + NADP(+).


go_id: GO:0033768
term: SUMO-targeted ubiquitin ligase complex
ontology: CC
definition:
A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.


go_id: GO:0033769
term: glyceollin synthase activity
ontology: MF
definition:
Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O.


go_id: GO:0033770
term: 2-hydroxyisoflavanone synthase activity
ontology: MF
definition:
Catalysis of the reaction: apigenin + 2 NADPH + 2 H+ + O2 = 2-hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O.


go_id: GO:0033772
term: flavonoid 3',5'-hydroxylase activity
ontology: MF
definition:
Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O.


go_id: GO:0033774
term: basal labyrinth
ontology: CC
definition:
A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane.


go_id: GO:0033777
term: lithocholate 6beta-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+).


go_id: GO:0033778
term: 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+).


