# go_term

go_id: GO:0018122
term: peptidyl-asparagine ADP-ribosylation
ontology: BP
definition:
The transfer, from NAD, of ADP-ribose to peptidyl-asparagine to form peptidyl-N4-(ADP-ribosyl)-L-asparagine.


go_id: GO:0018123
term: peptidyl-cysteine ADP-ribosylation
ontology: BP
definition:
The transfer, from NAD, of ADP-ribose to peptidyl-cysteine to form peptidyl-S-(ADP-ribosyl)-L-cysteine.


go_id: GO:0018124
term: peptide cross-linking via 5'-(N6-L-lysine)-L-topaquinone
ontology: BP
definition:
The cross-linking of the epsilon-amino group of a peptidyl-lysine with peptidyl-topaquinone, a modified tyrosine residue.


go_id: GO:0018130
term: heterocycle biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).


go_id: GO:0018131
term: oxazole or thiazole biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.


go_id: GO:0018132
term: peptide cross-linking via L-cysteine oxazolecarboxylic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


go_id: GO:0018133
term: peptide cross-linking via L-cysteine oxazolinecarboxylic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue.


go_id: GO:0018134
term: peptide cross-linking via glycine oxazolecarboxylic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


go_id: GO:0018137
term: peptide cross-linking via glycine thiazolecarboxylic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


go_id: GO:0018138
term: peptide cross-linking via L-serine thiazolecarboxylic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


go_id: GO:0018139
term: peptide cross-linking via L-phenylalanine thiazolecarboxylic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


go_id: GO:0018140
term: peptide cross-linking via L-cysteine thiazolecarboxylic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


go_id: GO:0018141
term: peptide cross-linking via L-lysine thiazolecarboxylic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


go_id: GO:0018145
term: protein-DNA covalent cross-linking via peptidyl-serine
ontology: BP
definition:
The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine.


go_id: GO:0018146
term: keratan sulfate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.


go_id: GO:0018147
term: molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)
ontology: BP
definition:
The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide).


go_id: GO:0018148
term: RNA-protein covalent cross-linking via peptidyl-tyrosine
ontology: BP
definition:
The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine.


go_id: GO:0018150
term: peptide cross-linking via 3-(3'-L-histidyl)-L-tyrosine
ontology: BP
definition:
The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3'-L-histidyl)-L-tyrosine protein cross-link.


go_id: GO:0018152
term: peptide cross-linking via 3'-(1'-L-histidyl)-L-tyrosine
ontology: BP
definition:
The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3'-(1'-L-histidyl)-L-tyrosine protein cross-link.


go_id: GO:0018153
term: isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine
ontology: BP
definition:
The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine.


go_id: GO:0018154
term: peptide cross-linking via (2R,6R)-lanthionine
ontology: BP
definition:
The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine).


go_id: GO:0018155
term: peptide cross-linking via sn-(2S,6R)-lanthionine
ontology: BP
definition:
The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione).


go_id: GO:0018156
term: peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine
ontology: BP
definition:
The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine).


go_id: GO:0018157
term: peptide cross-linking via an oxazole or thiazole
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


go_id: GO:0018160
term: peptidyl-pyrromethane cofactor linkage
ontology: BP
definition:
The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.


go_id: GO:0018161
term: dipyrrin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.


go_id: GO:0018162
term: peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine
ontology: BP
definition:
The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine.


go_id: GO:0018163
term: protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine
ontology: BP
definition:
The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine.


go_id: GO:0018164
term: protein-DNA covalent cross-linking via peptidyl-threonine
ontology: BP
definition:
The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine.


go_id: GO:0018165
term: peptidyl-tyrosine uridylylation
ontology: BP
definition:
The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase.


go_id: GO:0018166
term: C-terminal protein-tyrosinylation
ontology: BP
definition:
The ATP-dependent addition of a tyrosine residue to the C-terminus of a protein; typically the addition of tyrosine to the C-terminus of detyrosinated alpha-tubulin by the enzyme tubulin-tyrosine ligase.


go_id: GO:0018167
term: protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine
ontology: BP
definition:
The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine.


go_id: GO:0018168
term: protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine
ontology: BP
definition:
The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine.


go_id: GO:0018169
term: ribosomal S6-glutamic acid ligase activity
ontology: MF
definition:
Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6.


go_id: GO:0018170
term: C-terminal peptidyl-polyglutamic acid amidation
ontology: BP
definition:
The formation of a C-terminal peptidyl-polyglutamic acid to form a peptidyl-N-L-glutamyl-poly-L-glutamic acid C-terminus.


go_id: GO:0018171
term: peptidyl-cysteine oxidation
ontology: BP
definition:
The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid.


go_id: GO:0018173
term: peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine.


go_id: GO:0018181
term: peptidyl-arginine C5-methylation
ontology: BP
definition:
The methylation of peptidyl-arginine on the carbon 5 (C5) residue to form peptidyl-5-methyl-L-arginine.


go_id: GO:0018182
term: protein-heme linkage via 3'-L-histidine
ontology: BP
definition:
The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine).


go_id: GO:0018185
term: poly-N-methyl-propylamination
ontology: BP
definition:
The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin.


go_id: GO:0018189
term: pyrroloquinoline quinone biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.


go_id: GO:0018191
term: peptidyl-serine octanoylation
ontology: BP
definition:
The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin.


go_id: GO:0018192
term: enzyme active site formation via cysteine modification to L-cysteine persulfide
ontology: BP
definition:
The formation of an enzyme active site via modification of peptidyl-cysteine to peptidyl-L-cysteine persulfide.


go_id: GO:0018220
term: peptidyl-threonine palmitoylation
ontology: BP
definition:
The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine.


go_id: GO:0018221
term: peptidyl-serine palmitoylation
ontology: BP
definition:
The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine.


go_id: GO:0018226
term: peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine
ontology: BP
definition:
The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic.


go_id: GO:0018227
term: peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine
ontology: BP
definition:
The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine.


go_id: GO:0018228
term: peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine
ontology: BP
definition:
The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification.


go_id: GO:0018230
term: peptidyl-L-cysteine S-palmitoylation
ontology: BP
definition:
The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.


go_id: GO:0018231
term: peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
ontology: BP
definition:
The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3') and unsaturated (generally at 2') fatty acids.


go_id: GO:0018232
term: peptide cross-linking via S-(L-isoglutamyl)-L-cysteine
ontology: BP
definition:
The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link.


go_id: GO:0018233
term: peptide cross-linking via 2'-(S-L-cysteinyl)-L-histidine
ontology: BP
definition:
The modification of peptidyl-histidine and peptidyl-cysteine to form a 2'-(S-L-cysteinyl)-L-histidine protein cross-link.


go_id: GO:0018234
term: peptide cross-linking via 3'-(S-L-cysteinyl)-L-tyrosine
ontology: BP
definition:
The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase.


go_id: GO:0018240
term: protein S-linked glycosylation via cysteine
ontology: BP
definition:
The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine.


go_id: GO:0018241
term: protein O-linked glycosylation via hydroxylysine
ontology: BP
definition:
The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine.


go_id: GO:0018242
term: protein O-linked glycosylation via serine
ontology: BP
definition:
The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine.


go_id: GO:0018243
term: protein O-linked glycosylation via threonine
ontology: BP
definition:
The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine.


go_id: GO:0018244
term: protein N-linked glycosylation via tryptophan
ontology: BP
definition:
The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue.


go_id: GO:0018245
term: protein O-linked glycosylation via tyrosine
ontology: BP
definition:
The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen.


go_id: GO:0018247
term: protein-phosphoribosyl dephospho-coenzyme A linkage
ontology: BP
definition:
The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position.


go_id: GO:0018248
term: enzyme active site formation via peptidyl cysteine sulfation
ontology: BP
definition:
The formation of an enzyme active site via transient sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.


go_id: GO:0018250
term: peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine
ontology: BP
definition:
The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG.


go_id: GO:0018251
term: peptidyl-tyrosine dehydrogenation
ontology: BP
definition:
The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues.


go_id: GO:0018252
term: peptide cross-linking via L-seryl-5-imidazolinone glycine
ontology: BP
definition:
The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a serine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.


go_id: GO:0018253
term: peptide cross-linking via 5-imidazolinone glycine
ontology: BP
definition:
The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde.


go_id: GO:0018255
term: peptide cross-linking via S-glycyl-L-cysteine
ontology: BP
definition:
The formation of S-(peptidyl-glycyl)-peptidyl-cysteine cross-links by the formation of a thiolester between cysteine and the carboxy-terminal glycine of ubiquitin and other proteins.


go_id: GO:0018258
term: protein O-linked glycosylation via hydroxyproline
ontology: BP
definition:
The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline.


go_id: GO:0018259
term: RNA-protein covalent cross-linking via peptidyl-serine
ontology: BP
definition:
The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine.


go_id: GO:0018262
term: isopeptide cross-linking
ontology: BP
definition:
The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon.


go_id: GO:0018263
term: isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine
ontology: BP
definition:
The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine to produce N-(L-isoaspartyl)-L-cysteine.


go_id: GO:0018264
term: isopeptide cross-linking via N-(L-isoaspartyl)-glycine
ontology: BP
definition:
The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-glycine to produce N-(L-isoaspartyl)-glycine.


go_id: GO:0018265
term: GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


go_id: GO:0018266
term: GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


go_id: GO:0018267
term: GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


go_id: GO:0018268
term: GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


go_id: GO:0018269
term: GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


go_id: GO:0018270
term: GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


go_id: GO:0018274
term: peptide cross-linking via L-lysinoalanine
ontology: BP
definition:
The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link.


go_id: GO:0018276
term: isopeptide cross-linking via N6-glycyl-L-lysine
ontology: BP
definition:
The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination.


go_id: GO:0018279
term: protein N-linked glycosylation via asparagine
ontology: BP
definition:
The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification.


go_id: GO:0018280
term: protein S-linked glycosylation
ontology: BP
definition:
A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine.


go_id: GO:0018281
term: GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine
ontology: BP
definition:
The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


go_id: GO:0018282
term: metal incorporation into metallo-sulfur cluster
ontology: BP
definition:
The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide.


go_id: GO:0018284
term: iron incorporation into protein via tetrakis-L-cysteinyl iron
ontology: BP
definition:
The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein).


go_id: GO:0018285
term: iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide
ontology: BP
definition:
The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide.


go_id: GO:0018287
term: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide
ontology: BP
definition:
The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide.


go_id: GO:0018288
term: iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide
ontology: BP
definition:
The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide.


go_id: GO:0018290
ontology: BP
term:
iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide

definition:
The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase.


go_id: GO:0018299
ontology: BP
term:
iron incorporation into the Rieske iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide

definition:
The incorporation of iron into a Rieske 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide.


go_id: GO:0018301
ontology: BP
term:
iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon

definition:
The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon.


go_id: GO:0018302
ontology: BP
term:
iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide

definition:
The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide.


go_id: GO:0018303
ontology: BP
term:
iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide

definition:
The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide.


go_id: GO:0018304
term: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide
ontology: BP
definition:
The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide.


go_id: GO:0018305
term: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide
ontology: BP
definition:
The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide.


go_id: GO:0018306
ontology: BP
term:
iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide

definition:
The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide.


go_id: GO:0018311
term: peptidyl-N4-hydroxymethyl-L-asparagine biosynthetic process from peptidyl-asparagine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of N4-hydroxymethyl-L-asparagine from other compounds, including peptidyl-asparagine.


go_id: GO:0018313
term: peptide cross-linking via L-alanyl-5-imidazolinone glycine
ontology: BP
definition:
The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.


go_id: GO:0018316
term: peptide cross-linking via L-cystine
ontology: BP
definition:
The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.


go_id: GO:0018321
term: protein glucuronylation
ontology: BP
definition:
The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose.


go_id: GO:0018324
term: enzyme active site formation via L-cysteine sulfenic acid
ontology: BP
definition:
The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfenic acid, found in the active site of NADH peroxidase, nitrile hydratase, and peptide methionine sulfoxide reductase.


go_id: GO:0018327
term: enzyme active site formation via 1'-phospho-L-histidine
ontology: BP
definition:
The transient phosphorylation of peptidyl-histidine to form 1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine).


go_id: GO:0018328
term: enzyme active site formation via 3'-phospho-L-histidine
ontology: BP
definition:
The transient phosphorylation of peptidyl-histidine to form 3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).


go_id: GO:0018329
term: enzyme active site formation via N6-(phospho-5'-adenosine)-L-lysine
ontology: BP
definition:
The transient adenylylation of lysine to form N6-(phospho-5'-adenosine)-L-lysine, found in the active site of DNA ligase and RNA ligase.


go_id: GO:0018330
term: enzyme active site formation via N6-(phospho-5'-guanosine)-L-lysine
ontology: BP
definition:
The transient guanylylation of lysine to form N6-(phospho-5'-guanosine)-L-lysine, found in the guanylyltransferase active site of mRNA capping enzyme.


go_id: GO:0018332
term: enzyme active site formation via O-(phospho-5'-adenosine)-L-threonine
ontology: BP
definition:
The transient adenylylation of threonine to form N6-(phospho-5'-adenosine)-L-threonine, found in the active site of bovine phosphodiesterase I.


go_id: GO:0018335
term: protein succinylation
ontology: BP
definition:
The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue.


go_id: GO:0018339
term: peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid
ontology: BP
definition:
The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12.


go_id: GO:0018353
term: protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine
ontology: BP
definition:
The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine.


go_id: GO:0018355
ontology: BP
term:
protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine

definition:
The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine.


go_id: GO:0018356
term: protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine
ontology: BP
definition:
The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine.


go_id: GO:0018358
term: protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine
ontology: BP
definition:
The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine.


go_id: GO:0018363
term: peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium
ontology: BP
definition:
The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium.


go_id: GO:0018366
term: chiral amino acid racemization
ontology: BP
definition:
The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid.


go_id: GO:0018376
term: peptidyl-asparagine hydroxylation to form L-erythro-beta-hydroxyasparagine
ontology: BP
definition:
The hydroxylation of peptidyl-asparagine to form peptidyl-L-erythro-beta-hydroxyasparagine; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).


go_id: GO:0018386
term: N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine
ontology: BP
definition:
The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine.


go_id: GO:0018387
term: N-terminal peptidyl-amino acid deamination to pyruvic acid
ontology: BP
definition:
The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.


go_id: GO:0018388
term: N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine
ontology: BP
definition:
The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine.


go_id: GO:0018390
ontology: BP
term:
peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine

definition:
The methyl esterification of peptidyl-glutamic acid or peptidyl-glutamine to form the derivative glutamic acid 5-methyl ester.


go_id: GO:0018391
term: C-terminal peptidyl-glutamic acid tyrosinylation
ontology: BP
definition:
The ATP-dependent addition of a tyrosine residue to a glutamic acid residue at the C-terminus of a protein.


go_id: GO:0018392
term: glycoprotein 3-alpha-L-fucosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H(+).


go_id: GO:0018400
term: peptidyl-proline hydroxylation to 3-hydroxy-L-proline
ontology: BP
definition:
The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase.


go_id: GO:0018401
term: peptidyl-proline hydroxylation to 4-hydroxy-L-proline
ontology: BP
definition:
The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase.


go_id: GO:0018402
ontology: BP
term:
protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine

definition:
Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.


go_id: GO:0018403
ontology: BP
term:
protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine

definition:
Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.


go_id: GO:0018404
ontology: BP
term:
protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine

definition:
Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.


go_id: GO:0018405
ontology: BP
term:
protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine

definition:
Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues.


go_id: GO:0018406
term: protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan
ontology: BP
definition:
The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring.


go_id: GO:0018407
term: peptidyl-thyronine iodination to form 3',3'',5'-triiodo-L-thyronine
ontology: BP
definition:
The iodination of peptidyl-thyronine to form peptidyl-3',3'',5'-triiodo-L-thyronine (triiodothyronine).


go_id: GO:0018408
term: peptidyl-thyronine iodination to form 3',3'',5',5''-tetraiodo-L-thyronine
ontology: BP
definition:
The iodination of peptidyl-thyronine to form peptidyl-3',3'',5',5''-tetraiodo-L-thyronine (L-thyroxine).


go_id: GO:0018415
ontology: BP
term:
iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide

definition:
The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.


go_id: GO:0018416
ontology: BP
term:
nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide

definition:
The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.


go_id: GO:0018417
ontology: BP
term:
iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide

definition:
The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.


go_id: GO:0018418
ontology: BP
term:
nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide

definition:
The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.


go_id: GO:0018419
term: protein catenane formation
ontology: BP
definition:
The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain.


go_id: GO:0018423
term: protein C-terminal leucine carboxyl O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.


go_id: GO:0018424
term: peptidyl-glutamic acid poly-ADP-ribosylation
ontology: BP
definition:
This modification produces peptidyl-glutamic acid poly-ADP-ribose found in a number of nuclear proteins under certain conditions including the repair of single strand DNA breaks. The activated form of the generating enzyme poly(ADP-ribose) polymerase is itself modified in this way.


go_id: GO:0018425
term: O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds.


go_id: GO:0018426
term: O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage.


go_id: GO:0018429
ontology: BP
term:
copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide

definition:
The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide.


go_id: GO:0018441
term: iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide
ontology: BP
definition:
The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase.


go_id: GO:0018445
term: prothoracicotrophic hormone activity
ontology: MF
definition:
The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects.


go_id: GO:0018447
term: chloral hydrate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol.


go_id: GO:0018448
term: hydroxymethylmethylsilanediol oxidase activity
ontology: MF
definition:
Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O.


go_id: GO:0018462
term: 4-(hydroxymethyl)benzenesulfonate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate + H(+) + NADH.


go_id: GO:0018466
term: limonene-1,2-diol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene.


go_id: GO:0018472
term: 1-hydroxy-2-naphthaldehyde dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate.


go_id: GO:0018473
term: cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid.


go_id: GO:0018475
term: trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid.


go_id: GO:0018480
term: 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+.


go_id: GO:0018481
term: 4-hydroxymuconic-semialdehyde dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: <stereo>cis,trans</stereo>-4-hydroxymuconate semialdehyde + H(2)O + NAD(+) = 2 H(+) + maleylacetate + NADH.


go_id: GO:0018482
term: 4-formylbenzenesulfonate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-formylbenzenesulfonate + H(2)O + NAD(+) = 4-sulfobenzoate + 2 H(+) + NADH.


go_id: GO:0018489
term: vanillate monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: H(+) + NADH + O(2) + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H(2)O + NAD(+).


go_id: GO:0018490
term: 4-hydroxyphenylpyruvate oxidase activity
ontology: MF
definition:
Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O(2) = 2 (4-hydroxyphenyl)acetate + 2 CO(2).


go_id: GO:0018491
term: 2-oxobutyrate synthase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin.


go_id: GO:0018495
term: 2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA.


go_id: GO:0018496
term: 2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA.


go_id: GO:0018497
term: 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS.


go_id: GO:0018498
term: 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate.


go_id: GO:0018500
term: trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene.


go_id: GO:0018502
term: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone.


go_id: GO:0018503
term: trans-1,2-dihydrodiolphenanthrene dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene.


go_id: GO:0018505
term: cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+.


go_id: GO:0018507
term: cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = H(+) + NADH + phenanthrene-3,4-diol.


go_id: GO:0018508
term: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+.


go_id: GO:0018509
term: cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+.


go_id: GO:0018511
term: 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) = 2,3-dihydroxy-p-cumate + H(+) + NADH.


go_id: GO:0018513
term: dibenzothiophene dihydrodiol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-dihydroxydibenzothiophene + H(+) + NADH.


go_id: GO:0018516
term: 2,4-dichlorobenzoyl-CoA reductase activity
ontology: MF
definition:
Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP(+) = 2,4-dichlorobenzoyl-CoA + NADPH.


go_id: GO:0018517
term: phthalate 4,5-cis-dihydrodiol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + H(+) + NADH.


go_id: GO:0018518
term: 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH.


go_id: GO:0018519
term: cis-dihydroethylcatechol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + H(+) + NADH.


go_id: GO:0018520
term: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2.


go_id: GO:0018521
term: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO(2) + NADH.


go_id: GO:0018522
term: benzoyl-CoA reductase activity
ontology: MF
definition:
Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H(2)O + benzoyl-CoA + reduced ferredoxin.


go_id: GO:0018525
term: 4-hydroxybenzoyl-CoA reductase activity
ontology: MF
definition:
Catalysis of the reaction: benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin.


go_id: GO:0018529
term: nitrilotriacetate monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate.


go_id: GO:0018530
term: (R)-6-hydroxynicotine oxidase activity
ontology: MF
definition:
Catalysis of the reaction: (R)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2).


go_id: GO:0018531
term: (S)-6-hydroxynicotine oxidase activity
ontology: MF
definition:
Catalysis of the reaction: (S)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2).


go_id: GO:0018532
term: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin.


go_id: GO:0018537
term: coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity
ontology: MF
definition:
Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420.


go_id: GO:0018538
term: epoxide carboxylase activity
ontology: MF
definition:
Catalysis of the generic reaction: epoxide + CO2 + NAD+ + electron donor = beta-keto acid + NADH + reduced electron donor; the electron donor may be NADPH or a dithiol. This reaction is the ring opening and carboxylation of an epoxide; for example: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+.


go_id: GO:0018542
term: 2,3-dihydroxy DDT 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.


go_id: GO:0018543
term: 4-amino-2-nitroso-6-nitrotoluene reductase activity
ontology: MF
definition:
Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene.


go_id: GO:0018544
term: 4-carboxy-4'-sulfoazobenzene reductase activity
ontology: MF
definition:
Catalysis of the reaction: 4-carboxy-4'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate.


go_id: GO:0018545
term: NAD(P)H nitroreductase activity
ontology: MF
definition:
Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative.


go_id: GO:0018548
term: pentaerythritol trinitrate reductase activity
ontology: MF
definition:
Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate.


go_id: GO:0018549
term: methanethiol oxidase activity
ontology: MF
definition:
Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide.


go_id: GO:0018550
term: tetrachloro-p-hydroquinone reductive dehalogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl.


go_id: GO:0018553
term: 3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate.


go_id: GO:0018554
term: 1,2-dihydroxynaphthalene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached.


go_id: GO:0018555
term: phenanthrene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ + cis-3,4-dihydroxy-3,4-dihydrophenanthrene.


go_id: GO:0018556
term: 2,2',3-trihydroxybiphenyl dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate).


go_id: GO:0018557
term: 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid.


go_id: GO:0018558
term: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon.


go_id: GO:0018559
term: 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate.


go_id: GO:0018561
term: 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate.


go_id: GO:0018562
term: 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid.


go_id: GO:0018565
term: dihydroxydibenzothiophene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.


go_id: GO:0018566
term: 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate.


go_id: GO:0018568
term: 3,4-dihydroxyphenanthrene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate.


go_id: GO:0018570
term: p-cumate 2,3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate.


go_id: GO:0018571
term: 2,3-dihydroxy-p-cumate dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate.


go_id: GO:0018574
term: 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate.


go_id: GO:0018582
term: 1-hydroxy-2-naphthoate 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate.


go_id: GO:0018583
term: biphenyl-2,3-diol 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O.


go_id: GO:0018584
term: 2,4,5-trichlorophenoxyacetic acid oxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol.


go_id: GO:0018596
term: dimethylsilanediol hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol.


go_id: GO:0018597
term: ammonia monooxygenase activity
ontology: MF
definition:
Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions.


go_id: GO:0018602
term: 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2.


go_id: GO:0018606
term: benzenesulfonate dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol.


go_id: GO:0018609
term: chlorobenzene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).


go_id: GO:0018611
term: toluate dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate.


go_id: GO:0018612
term: dibenzothiophene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene.


go_id: GO:0018613
term: 9-fluorenone dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone.


go_id: GO:0018614
term: ethylbenzene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene.


go_id: GO:0018619
term: benzene 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: benzene + H(+) + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+).


go_id: GO:0018620
term: phthalate 4,5-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: H(+) + NADH + O(2) + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+).


go_id: GO:0018621
term: 4-sulfobenzoate 3,4-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-sulfobenzoate + H(+) + NADH + O(2) = 3,4-dihydroxybenzoate + NAD(+) + sulfite.


go_id: GO:0018622
term: 4-chlorophenylacetate 3,4-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-chlorophenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate + chloride + NAD(+).


go_id: GO:0018624
term: toluene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: H(+) + NADH + O(2) + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+).


go_id: GO:0018625
term: naphthalene 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+.


go_id: GO:0018627
term: 2-aminobenzenesulfonate 2,3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H(+) + NADH + O(2) = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH(4)(+). 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol.


go_id: GO:0018628
term: terephthalate 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: H(+) + NADH + O(2) + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+).


go_id: GO:0018629
term: 2-hydroxyquinoline 5,6-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+.


go_id: GO:0018635
term: (R)-limonene 1,2-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: (4R)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4R)-limonene-1,2-epoxide.


go_id: GO:0018637
term: 1-hydroxy-2-naphthoate hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene.


go_id: GO:0018639
term: xylene monooxygenase activity
ontology: MF
definition:
Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol.


go_id: GO:0018640
term: dibenzothiophene monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O.


go_id: GO:0018641
term: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.


go_id: GO:0018646
term: 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate.


go_id: GO:0018653
term: 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.


go_id: GO:0018655
term: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA.


go_id: GO:0018660
term: 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity
ontology: MF
definition:
Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O.


go_id: GO:0018663
term: 2,6-dihydroxypyridine 3-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,6-dihydroxypyridine + H(+) + NADH + O(2) = 2,3,6-trihydroxypyridine + H(2)O + NAD(+).


go_id: GO:0018666
term: 2,4-dichlorophenol 6-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O.


go_id: GO:0018668
term: 3-hydroxybenzoate 4-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADPH + O(2) = 3,4-dihydroxybenzoate + H(2)O + NADP(+).


go_id: GO:0018669
term: 3-hydroxybenzoate 6-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADH + O(2) = 2,5-dihydroxybenzoate + H(2)O + NAD(+).


go_id: GO:0018670
term: 4-aminobenzoate 1-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2.


go_id: GO:0018671
term: 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity
ontology: MF
definition:
Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O.


go_id: GO:0018672
term: anthranilate 3-monooxygenase (deaminating) activity
ontology: MF
definition:
Catalysis of the reaction: anthranilate + 2 H(+) + NADPH + O(2) = 2,3-dihydroxybenzoate + NADP(+) + NH(4)(+).


go_id: GO:0018673
term: anthraniloyl-CoA monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+.


go_id: GO:0018674
term: (S)-limonene 3-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (1S,6R)-isopiperitenol + H(2)O + NADP(+).


go_id: GO:0018676
term: (S)-limonene 7-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (4S)-perillyl alcohol + H(2)O + NADP(+).


go_id: GO:0018677
term: pentachlorophenol monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride.


go_id: GO:0018679
term: dibenzothiophene-5,5-dioxide monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate.


go_id: GO:0018681
term: deisopropylatrazine monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine.


go_id: GO:0018683
term: camphor 5-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O.


go_id: GO:0018684
term: camphor 1,2-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: (1R)-bornane-2,5-dione + reduced rubredoxin + O2 = 5-oxo-1,2-campholide + oxidized rubredoxin + H2O.


go_id: GO:0018685
term: alkane 1-monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.


go_id: GO:0018687
term: biphenyl 2,3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.


go_id: GO:0018688
term: DDT 2,3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT.


go_id: GO:0018689
term: naphthalene disulfonate 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene).


go_id: GO:0018690
term: 4-methoxybenzoate monooxygenase (O-demethylating) activity
ontology: MF
definition:
Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + A + formaldehyde + H(2)O.


go_id: GO:0018700
term: 2-chloro-N-isopropylacetanilide reductive dehalogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide.


go_id: GO:0018701
term: 2,5-dichlorohydroquinone reductive dehalogenase activity
ontology: MF
definition:
Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone).


go_id: GO:0018702
term: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.


go_id: GO:0018703
term: 2,4-dichlorophenoxyacetate dehalogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate.


go_id: GO:0018706
term: pyrogallol hydroxytransferase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.


go_id: GO:0018708
term: thiol S-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether.


go_id: GO:0018710
term: acetone carboxylase activity
ontology: MF
definition:
Catalysis of the reaction: acetone + ATP + CO(2) + 2 H(2)O = acetoacetate + AMP + 4 H(+) + 2 phosphate.


go_id: GO:0018715
term: 9-phenanthrol UDP-glucuronosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP.


go_id: GO:0018718
term: 1,2-dihydroxy-phenanthrene glycosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.


go_id: GO:0018721
term: trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate.


go_id: GO:0018725
term: trans-3,4-dihydrodiolphenanthrene sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate.


go_id: GO:0018742
term: epoxide hydrolase B activity
ontology: MF
definition:
Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers.


go_id: GO:0018744
term: limonene-1,2-epoxide hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide.


go_id: GO:0018745
term: epoxide hydrolase A activity
ontology: MF
definition:
Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol.


go_id: GO:0018749
term: (3,5-dichlorophenylurea)acetate amidohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine.


go_id: GO:0018755
term: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-.


go_id: GO:0018757
term: deisopropylhydroxyatrazine aminohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine.


go_id: GO:0018758
term: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine aminohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid.


go_id: GO:0018759
term: methenyltetrahydromethanopterin cyclohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H(+).


go_id: GO:0018761
term: bromoxynil nitrilase activity
ontology: MF
definition:
Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H(2)O = 3,5-dibromo-4-hydroxybenzoate + NH(4)(+). Involved in the bacterial degradation of the herbicide bromoxynil.


go_id: GO:0018763
term: hydroxydechloroatrazine ethylaminohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine.


go_id: GO:0018765
term: 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate.


go_id: GO:0018767
term: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate.


go_id: GO:0018768
term: 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate.


go_id: GO:0018769
term: 2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate.


go_id: GO:0018770
term: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+.


go_id: GO:0018771
term: 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate.


go_id: GO:0018777
term: 1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol).


go_id: GO:0018783
term: deisopropyldeethylatrazine hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3.


go_id: GO:0018788
term: atrazine chlorohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H(+).


go_id: GO:0018791
term: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate.


go_id: GO:0018792
term: bis(4-chlorophenyl)acetate decarboxylase activity
ontology: MF
definition:
Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM.


go_id: GO:0018802
term: 2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde.


go_id: GO:0018803
term: 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity
ontology: MF
definition:
Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate.


go_id: GO:0018807
term: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity
ontology: MF
definition:
Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA.


go_id: GO:0018808
term: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity
ontology: MF
definition:
Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde.


go_id: GO:0018810
term: trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity
ontology: MF
definition:
Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene.


go_id: GO:0018811
term: cyclohex-1-ene-1-carboxyl-CoA hydratase activity
ontology: MF
definition:
Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA.


go_id: GO:0018812
term: 3-hydroxyacyl-CoA dehydratase activity
ontology: MF
definition:
Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA).


go_id: GO:0018813
term: trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde).


go_id: GO:0018815
term: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity
ontology: MF
definition:
Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = 2-oxobut-3-enanoate + 2,5,6-trihydroxy-3-methylpyridine.


go_id: GO:0018817
term: 2-oxo-hept-3-ene-1,7-dioate hydratase activity
ontology: MF
definition:
Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate.


go_id: GO:0018823
term: cyclohexa-1,5-dienecarbonyl-CoA hydratase activity
ontology: MF
definition:
Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H(2)O = 6-hydroxycyclohex-1-enecarbonyl-CoA.


go_id: GO:0018827
term: 1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity
ontology: MF
definition:
Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU.


go_id: GO:0018829
term: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity
ontology: MF
definition:
Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.


go_id: GO:0018830
term: gamma-hexachlorocyclohexane dehydrochlorinase activity
ontology: MF
definition:
Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene.


go_id: GO:0018831
term: 5-chloro-1,2,4-trihydroxybenzene dechlorinase activity
ontology: MF
definition:
Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone.


go_id: GO:0018833
term: DDT-dehydrochlorinase activity
ontology: MF
definition:
Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+).


go_id: GO:0018835
term: carbon phosphorus lyase activity
ontology: MF
definition:
Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate).


go_id: GO:0018837
term: 2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate.


go_id: GO:0018839
term: cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity
ontology: MF
definition:
Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.


go_id: GO:0018845
term: 2-hydroxychromene-2-carboxylate isomerase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate.


go_id: GO:0018852
term: dichloromuconate cycloisomerase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate.


go_id: GO:0018854
term: 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity
ontology: MF
definition:
Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.


go_id: GO:0018855
term: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA.


go_id: GO:0018856
term: benzoyl acetate-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA.


go_id: GO:0018857
term: 2,4-dichlorobenzoate-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA.


go_id: GO:0018859
term: 4-hydroxybenzoate-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA.


go_id: GO:0018861
term: 4-chlorobenzoate-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway.


go_id: GO:0018863
term: phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity
ontology: MF
definition:
Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene.


go_id: GO:0018864
term: acetylene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes.


go_id: GO:0018865
term: acrylonitrile metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.


go_id: GO:0018866
term: adamantanone metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.


go_id: GO:0018867
term: alpha-pinene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor.


go_id: GO:0018868
term: 2-aminobenzenesulfonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.


go_id: GO:0018870
term: anaerobic 2-aminobenzoate metabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen.


go_id: GO:0018871
term: 1-aminocyclopropane-1-carboxylate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.


go_id: GO:0018872
term: arsonoacetate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides.


go_id: GO:0018873
term: atrazine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide.


go_id: GO:0018874
term: benzoate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.


go_id: GO:0018875
term: anaerobic benzoate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the absence of oxygen.


go_id: GO:0018876
term: benzonitrile metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin.


go_id: GO:0018877
term: beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.


go_id: GO:0018878
term: aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane that occur in presence of oxygen.


go_id: GO:0018879
term: biphenyl metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).


go_id: GO:0018880
term: 4-chlorobiphenyl metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation.


go_id: GO:0018881
term: bromoxynil metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants.


go_id: GO:0018882
term: (+)-camphor metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed.


go_id: GO:0018883
term: caprolactam metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. It can cause local irritation.


go_id: GO:0018884
term: carbazole metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.


go_id: GO:0018885
term: carbon tetrachloride metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.


go_id: GO:0018886
term: anaerobic carbon tetrachloride metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen.


go_id: GO:0018887
term: 4-carboxy-4'-sulfoazobenzene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid.


go_id: GO:0018888
term: 3-chloroacrylic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid.


go_id: GO:0018889
term: 2-chloro-N-isopropylacetanilide metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.


go_id: GO:0018890
term: cyanamide metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.


go_id: GO:0018891
term: cyclohexanol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent.


go_id: GO:0018892
term: cyclohexylsulfamate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide.


go_id: GO:0018893
term: dibenzofuran metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals.


go_id: GO:0018894
term: dibenzo-p-dioxin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern.


go_id: GO:0018895
term: dibenzothiophene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion.


go_id: GO:0018896
term: dibenzothiophene catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.


go_id: GO:0018897
term: dibenzothiophene desulfurization
ontology: BP
definition:
The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.


go_id: GO:0018898
term: 2,4-dichlorobenzoate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).


go_id: GO:0018899
term: 1,2-dichloroethane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.


go_id: GO:0018900
term: dichloromethane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover.


go_id: GO:0018901
term: 2,4-dichlorophenoxyacetic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.


go_id: GO:0018902
term: 1,3-dichloro-2-propanol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. DCP is used as a general solvent, as an intermediate in organic synthesis and in paints, varnishes, lacquers, water colors, binders and photographic lacquers.


go_id: GO:0018903
term: 1,3-dichloropropene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes.


go_id: GO:0018904
term: ether metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds.


go_id: GO:0018905
term: dimethyl ether metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications.


go_id: GO:0018906
term: methyl tert-butyl ether metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent.


go_id: GO:0018907
term: dimethyl sulfoxide metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing.


go_id: GO:0018908
term: organosulfide cycle
ontology: BP
definition:
A cyclic series of interconversions involving dimethyl sulfide, methanethiol and hydrogen sulfide. Dimethylsulfoxide can also be converted to dimethyl sulfide, which enters the cycle.


go_id: GO:0018909
term: dodecyl sulfate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants.


go_id: GO:0018910
term: benzene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation.


go_id: GO:0018911
term: 1,2,4-trichlorobenzene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides.


go_id: GO:0018912
term: 1,4-dichlorobenzene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs.


go_id: GO:0018913
term: anaerobic ethylbenzene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen.


go_id: GO:0018914
term: chlorobenzene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone.


go_id: GO:0018915
term: ethylbenzene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels.


go_id: GO:0018916
term: nitrobenzene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline.


go_id: GO:0018917
term: fluorene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.


go_id: GO:0018918
term: gallate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid). The esters and polyesters are widely distributed in angiosperms.


go_id: GO:0018919
term: gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.


go_id: GO:0018920
term: glyphosate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond.


go_id: GO:0018921
term: 3-hydroxybenzyl alcohol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum.


go_id: GO:0018922
term: iprodione metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium).


go_id: GO:0018923
term: limonene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.


go_id: GO:0018924
term: mandelate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.


go_id: GO:0018925
term: m-cresol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes.


go_id: GO:0018926
term: methanesulfonic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide.


go_id: GO:0018928
term: methyl ethyl ketone metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints.


go_id: GO:0018929
term: methyl fluoride metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving methyl fluoride, fluorine-substituted methane, a gaseous halogenated hydrocarbon that has been investigated as an inhibitor of methanotrophy and nitrification in soils.


go_id: GO:0018930
term: 3-methylquinoline metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.


go_id: GO:0018931
term: naphthalene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving naphthalene, a fused ring bicyclic aromatic hydrocarbon commonly found in crude oil and oil products. Naphthalene is familiar as the compound that gives mothballs their odor; it is used in the manufacture of plastics, dyes, solvents, and other chemicals, as well as being used as an antiseptic and insecticide.


go_id: GO:0018934
term: nitrilotriacetate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment.


go_id: GO:0018935
term: aerobic nitrilotriacetate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen.


go_id: GO:0018936
term: anaerobic nitrilotriacetate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen.


go_id: GO:0018937
term: nitroglycerin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates.


go_id: GO:0018938
term: 2-nitropropane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol.


go_id: GO:0018939
term: n-octane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System.


go_id: GO:0018940
term: orcinol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants.


go_id: GO:0018941
term: organomercury metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving organomercury compound, any organic compound containing a mercury atom.


go_id: GO:0018942
term: organometal metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms.


go_id: GO:0018944
term: tri-n-butyltin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms.


go_id: GO:0018945
term: organosilicon metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon.


go_id: GO:0018946
term: aerobic organosilicon metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen.


go_id: GO:0018947
term: anaerobic organosilicon metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the absence of oxygen.


go_id: GO:0018948
term: xylene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.


go_id: GO:0018949
term: m-xylene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.


go_id: GO:0018950
term: o-xylene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.


go_id: GO:0018951
term: p-xylene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.


go_id: GO:0018952
term: parathion metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.


go_id: GO:0018953
term: p-cymene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.


go_id: GO:0018954
term: pentaerythritol tetranitrate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving pentaerythritol tetranitrate, C(CH2-O-NO2)4, a substance produced for use as an explosive and a vasodilator.


go_id: GO:0018955
term: phenanthrene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish.


go_id: GO:0018956
term: phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite.


go_id: GO:0018957
term: phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite.


go_id: GO:0018958
term: phenol-containing compound metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.


go_id: GO:0018959
term: aerobic phenol-containing compound metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.


go_id: GO:0018960
term: 4-nitrophenol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.


go_id: GO:0018961
term: pentachlorophenol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.


go_id: GO:0018962
term: 3-phenylpropionate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins.


go_id: GO:0018963
term: phthalate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses.


go_id: GO:0018964
term: propylene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals.


go_id: GO:0018965
term: s-triazine compound metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.


go_id: GO:0018966
term: styrene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen.


go_id: GO:0018967
term: tetrachloroethylene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent.


go_id: GO:0018968
term: tetrahydrofuran metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems.


go_id: GO:0018969
term: thiocyanate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries.


go_id: GO:0018970
term: toluene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications.


go_id: GO:0018971
term: anaerobic toluene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen.


go_id: GO:0018972
term: toluene-4-sulfonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water.


go_id: GO:0018973
term: trinitrotoluene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.


go_id: GO:0018974
term: 2,4,6-trinitrotoluene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives.


go_id: GO:0018975
term: anaerobic 2,4,6-trinitrotoluene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen.


go_id: GO:0018976
term: 1,2,3-tribromopropane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture.


go_id: GO:0018977
term: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.


go_id: GO:0018978
term: anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen.


go_id: GO:0018979
term: trichloroethylene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.


go_id: GO:0018980
term: 2,4,5-trichlorophenoxyacetic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns.


go_id: GO:0018981
term: triethanolamine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent.


go_id: GO:0018982
term: vanillin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin.


go_id: GO:0018983
term: Z-phenylacetaldoxime metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants.


go_id: GO:0018984
term: naphthalenesulfonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene.


go_id: GO:0018996
term: molting cycle, collagen and cuticulin-based cuticle
ontology: BP
definition:
The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans.


go_id: GO:0018989
term: apolysis
ontology: BP
definition:
The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells.


go_id: GO:0018990
term: ecdysis, chitin-based cuticle
ontology: BP
definition:
The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster.


go_id: GO:0018995
term: host
ontology: CC
definition:
Any organism in which another organism, especially a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection.


go_id: GO:0019001
term: guanyl nucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate.


go_id: GO:0019008
term: molybdopterin synthase complex
ontology: CC
definition:
A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits.


go_id: GO:0019010
term: farnesoic acid O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: farnesoic acid + S-adenosyl-methionine = methyl farnesoate + S-adenosyl-L-homocysteine.


go_id: GO:0019013
term: viral nucleocapsid
ontology: CC
definition:
The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.


go_id: GO:0019017
term: segmented viral genome
ontology: CC
definition:
A viral genome that is divided into two or more physically separate molecules of nucleic acid and packaged into a single virion.


go_id: GO:0019018
term: bipartite viral genome
ontology: CC
definition:
A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.


go_id: GO:0019019
term: tripartite viral genome
ontology: CC
definition:
A segmented viral genome consisting of three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.


go_id: GO:0019020
term: multipartite viral genome
ontology: CC
definition:
A segmented viral genome consisting of more than three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.


go_id: GO:0019022
term: RNA viral genome
ontology: CC
definition:
A viral genome composed of ribonucleic acid. This results in genome replication and expression of genetic information being inextricably linked.


go_id: GO:0019027
term: ambisense viral genome
ontology: CC
definition:
A RNA genome that contains coding regions that are either positive sense or negative sense on the same RNA molecule.


go_id: GO:0019028
term: viral capsid
ontology: CC
definition:
The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres.


go_id: GO:0019029
term: helical viral capsid
ontology: CC
definition:
The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure.


go_id: GO:0019030
term: icosahedral viral capsid
ontology: CC
definition:
The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form an icosahedron, a solid with 20 faces and 12 vertices. Icosahedral capsids have 12 pentamers plus 10(T-1) hexamers, where T is the triangulation number. Tobacco satellite necrosis virus has such a capsid structure.


go_id: GO:0019033
term: viral tegument
ontology: CC
definition:
A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically.


go_id: GO:0019034
term: viral replication complex
ontology: CC
definition:
Specific locations and structures in the virus infected cell involved in replicating the viral genome.


go_id: GO:0019035
term: viral integration complex
ontology: CC
definition:
A nucleoprotein complex containing viral genetic material and associated viral and host proteins, which is capable of inserting a viral genome into a host genome.


go_id: GO:0019036
term: viral transcriptional complex
ontology: CC
definition:
Specific locations and structures in the virus infected cell involved in transcribing the viral genome.


go_id: GO:0019038
term: provirus
ontology: CC
definition:
The name given to a viral genome after it has been integrated into the host genome; particularly applies to retroviruses and is a required part of the retroviral replication cycle.


go_id: GO:0019064
term: fusion of virus membrane with host plasma membrane
ontology: BP
definition:
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.


go_id: GO:0019042
term: viral latency
ontology: BP
definition:
The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate.


go_id: GO:0019043
term: establishment of viral latency
ontology: BP
definition:
A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects.


go_id: GO:0019044
term: maintenance of viral latency
ontology: BP
definition:
The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms.


go_id: GO:0019046
term: release from viral latency
ontology: BP
definition:
The process by which a virus switches from latency and begins to replicate. It may be effected by various endogenous and exogenous stimuli, including B-cell lipopolysaccharides, glucocorticoid hormones, halogenated pyrimidines, ionizing radiation, ultraviolet light, various chemicals and super-infecting viruses.


go_id: GO:0019049
term: evasion or tolerance of host defenses by virus
ontology: BP
definition:
Any process, either active or passive, by which a virus avoids or tolerates the effects of its host organism's defense(s). Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0019050
term: suppression by virus of host apoptotic process
ontology: BP
definition:
Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.


go_id: GO:0019051
term: induction by virus of host apoptotic process
ontology: BP
definition:
The set of viral processes that induce an apoptotic process in infected host cells, facilitating release and spread of progeny virions.


go_id: GO:0019055
term: modification by virus of host cell cycle regulation
ontology: BP
definition:
Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication.


go_id: GO:0019058
term: viral life cycle
ontology: BP
definition:
A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.


go_id: GO:0046718
term: viral entry into host cell
ontology: BP
definition:
The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.


go_id: GO:0019061
term: uncoating of virus
ontology: BP
definition:
The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome.


go_id: GO:0019062
term: virion attachment to host cell
ontology: BP
definition:
The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.


go_id: GO:0019065
term: receptor-mediated endocytosis of virus by host cell
ontology: BP
definition:
Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell.


go_id: GO:0019068
term: virion assembly
ontology: BP
definition:
A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed.


go_id: GO:0019070
term: viral genome maturation
ontology: BP
definition:
The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes.


go_id: GO:0019075
term: virus maturation
ontology: BP
definition:
The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release.


go_id: GO:0019076
term: viral release from host cell
ontology: BP
definition:
The dissemination of mature viral particles from the host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane.


go_id: GO:0019080
term: viral gene expression
ontology: BP
definition:
A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation.


go_id: GO:0019082
term: viral protein processing
ontology: BP
definition:
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein.


go_id: GO:0019083
term: viral transcription
ontology: BP
definition:
The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.


go_id: GO:0019084
term: middle viral transcription
ontology: BP
definition:
The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication.


go_id: GO:0019085
term: early viral transcription
ontology: BP
definition:
The first phase of viral transcription that occurs after entry of the virus into the host cell, but prior to viral genome replication. It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell.


go_id: GO:0019086
term: late viral transcription
ontology: BP
definition:
The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins.


go_id: GO:0019088
term: immortalization of host cell by virus
ontology: BP
definition:
A virus-induced cellular transformation arising in immortalized cells, or cells capable of indefinite replication, due to their ability to produce their own telomerase.


go_id: GO:0019094
term: pole plasm mRNA localization
ontology: BP
definition:
Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


go_id: GO:0019095
term: pole plasm mitochondrial rRNA localization
ontology: BP
definition:
Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


go_id: GO:0019096
term: pole plasm mitochondrial lrRNA localization
ontology: BP
definition:
Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


go_id: GO:0019097
term: pole plasm mitochondrial srRNA localization
ontology: BP
definition:
Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


go_id: GO:0019103
term: pyrimidine nucleotide binding
ontology: MF
definition:
Interacting selectively and non-covalently with pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate.


go_id: GO:0019116
term: hydroxy-nicotine oxidase activity
ontology: MF
definition:
Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide.


go_id: GO:0019117
term: dihydroxyfluorene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid.


go_id: GO:0019120
term: hydrolase activity, acting on acid halide bonds, in C-halide compounds
ontology: MF
definition:
Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage.


go_id: GO:0019121
term: peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine
ontology: BP
definition:
The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan.


go_id: GO:0019133
term: choline monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O.


go_id: GO:0019134
term: glucosamine-1-phosphate N-acetyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H(+).


go_id: GO:0019135
term: deoxyhypusine monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.


go_id: GO:0019139
term: cytokinin dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.


go_id: GO:0019141
term: 2-dehydropantolactone reductase (B-specific) activity
ontology: MF
definition:
Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.


go_id: GO:0019143
term: 3-deoxy-manno-octulosonate-8-phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H(2)O = 3-deoxy-D-manno-octulosonate + phosphate.


go_id: GO:0019155
term: 3-(imidazol-5-yl)lactate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+.


go_id: GO:0019156
term: isoamylase activity
ontology: MF
definition:
Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins.


go_id: GO:0019159
term: nicotinamide-nucleotide amidase activity
ontology: MF
definition:
Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3.


go_id: GO:0019160
term: NMN nucleosidase activity
ontology: MF
definition:
Catalysis of the reaction: H(2)O + nicotinamide mononucleotide = D-ribose 5-phosphate + H(+) + nicotinamide.


go_id: GO:0019161
term: diamine transaminase activity
ontology: MF
definition:
Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate.


go_id: GO:0019163
term: pyridoxamine-phosphate transaminase activity
ontology: MF
definition:
Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate.


go_id: GO:0019164
term: pyruvate synthase activity
ontology: MF
definition:
Catalysis of the reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.


go_id: GO:0019168
term: 2-octaprenylphenol hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O.


go_id: GO:0019171
term: 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
ontology: MF
definition:
Catalysis of the reaction: a (3R)-3-hydroxyacyl-[acyl-carrier protein] = H2O + a trans-delta2-enoyl-acyl-[acyl-carrier protein].


go_id: GO:0019174
term: tetrahydrothiophene 1-oxide reductase activity
ontology: MF
definition:
Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor.


go_id: GO:0019177
term: dihydroneopterin triphosphate pyrophosphohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate.


go_id: GO:0019179
term: dTDP-4-amino-4,6-dideoxy-D-glucose transaminase activity
ontology: MF
definition:
Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate.


go_id: GO:0019180
term: dTDP-4-amino-4,6-dideoxygalactose transaminase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose.


go_id: GO:0019182
term: histamine-gated chloride channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts.


go_id: GO:0019183
term: histamine-gated chloride channel complex
ontology: CC
definition:
A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts.


go_id: GO:0019184
term: nonribosomal peptide biosynthetic process
ontology: BP
definition:
The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.


go_id: GO:0019185
term: snRNA-activating protein complex
ontology: CC
definition:
A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.


go_id: GO:0019186
term: acyl-CoA N-acyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule.


go_id: GO:0019187
term: beta-1,4-mannosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage.


go_id: GO:0019191
term: cellobiose transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of cellobiose from one side of the membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.


go_id: GO:0019194
term: sorbose transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of sorbose from one side of the membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.


go_id: GO:0019196
term: galactosamine transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of galactosamine from one side of the membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative.


go_id: GO:0019197
term: phosphoenolpyruvate-dependent sugar phosphotransferase complex
ontology: CC
definition:
Includes phosphoenolpyruvate-protein phosphatase (enzyme I of the phosphotransferase system) and protein-N(PI)-phosphohistidine-sugar phosphotransferase (enzyme II of the phosphotransferase system).


go_id: GO:0019198
term: transmembrane receptor protein phosphatase activity
ontology: MF
definition:
Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate.


go_id: GO:0019199
term: transmembrane receptor protein kinase activity
ontology: MF
definition:
Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.


go_id: GO:0019200
term: carbohydrate kinase activity
ontology: MF
definition:
Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule.


go_id: GO:0019205
term: nucleobase-containing compound kinase activity
ontology: MF
definition:
Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate.


go_id: GO:0019207
term: kinase regulator activity
ontology: MF
definition:
Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.


go_id: GO:0019208
term: phosphatase regulator activity
ontology: MF
definition:
Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.


go_id: GO:0019209
term: kinase activator activity
ontology: MF
definition:
Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.


go_id: GO:0019210
term: kinase inhibitor activity
ontology: MF
definition:
Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.


go_id: GO:0019211
term: phosphatase activator activity
ontology: MF
definition:
Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.


go_id: GO:0019212
term: phosphatase inhibitor activity
ontology: MF
definition:
Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.


go_id: GO:0050828
term: regulation of liquid surface tension
ontology: BP
definition:
Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid.


go_id: GO:0019215
term: intermediate filament binding
ontology: MF
definition:
Interacting selectively and non-covalently with an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space.


go_id: GO:0019216
term: regulation of lipid metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.


go_id: GO:0019217
term: regulation of fatty acid metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.


go_id: GO:0019218
term: regulation of steroid metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.


go_id: GO:0019219
term: regulation of nucleobase-containing compound metabolic process
ontology: BP
definition:
Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.


go_id: GO:0019220
term: regulation of phosphate metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.


go_id: GO:0019221
term: cytokine-mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0019222
term: regulation of metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.


go_id: GO:0019226
term: transmission of nerve impulse
ontology: BP
definition:
The neurological system process in which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation.


go_id: GO:0019227
term: neuronal action potential propagation
ontology: BP
definition:
A neurological process that causes the sequential depolarization of a neuron's cell membrane along an axon.


go_id: GO:0019229
term: regulation of vasoconstriction
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.


go_id: GO:0019230
term: proprioception
ontology: BP
definition:
The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors.


go_id: GO:0019232
term: perception of rate of movement
ontology: BP
definition:
The series of events by which an organism senses the speed and direction of movement of the body and its parts.


go_id: GO:0019233
term: sensory perception of pain
ontology: BP
definition:
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.


go_id: GO:0019234
term: sensory perception of fast pain
ontology: BP
definition:
The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds.


go_id: GO:0019235
term: sensory perception of slow pain
ontology: BP
definition:
The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction.


go_id: GO:0019236
term: response to pheromone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.


go_id: GO:0019238
term: cyclohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring.


go_id: GO:0019240
term: citrulline biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.


go_id: GO:0019241
term: citrulline catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.


go_id: GO:0019242
term: methylglyoxal biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.


go_id: GO:0019243
term: methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.


go_id: GO:0019244
term: lactate biosynthetic process from pyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate.


go_id: GO:0019245
term: D(-)-lactate biosynthetic process from pyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of D(-)-lactate from other compounds, including pyruvate.


go_id: GO:0019246
term: L(+)-lactate biosynthetic process from pyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate.


go_id: GO:0019247
term: lactate racemization
ontology: BP
definition:
Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture.


go_id: GO:0019248
term: D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of D-lactate from methylglyoxal, via the intermediate (R)-lactaldehyde.


go_id: GO:0019249
term: lactate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid.


go_id: GO:0019250
term: aerobic cobalamin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen.


go_id: GO:0019251
term: anaerobic cobalamin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen.


go_id: GO:0019252
term: starch biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants.


go_id: GO:0019253
term: reductive pentose-phosphate cycle
ontology: BP
definition:
The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate.


go_id: GO:0019255
term: glucose 1-phosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1.


go_id: GO:0019256
term: acrylonitrile catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.


go_id: GO:0019257
term: 4-nitrotoluene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 4-nitrotoluene, 1-methyl-4-nitrobenzene. It is a light yellow liquid with a weak aromatic odor.


go_id: GO:0019258
term: 4-nitrotoluene catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene.


go_id: GO:0019260
term: 1,2-dichloroethane catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.


go_id: GO:0019261
term: 1,4-dichlorobenzene catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring.


go_id: GO:0019262
term: N-acetylneuraminate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.


go_id: GO:0019263
term: adamantanone catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.


go_id: GO:0019264
term: glycine biosynthetic process from serine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine.


go_id: GO:0019265
term: glycine biosynthetic process, by transamination of glyoxylate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate.


go_id: GO:0019266
term: asparagine biosynthetic process from oxaloacetate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate.


go_id: GO:0019267
term: asparagine biosynthetic process from cysteine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine.


go_id: GO:0019270
term: aerobactin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.


go_id: GO:0019271
term: aerobactin transport
ontology: BP
definition:
The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.


go_id: GO:0019272
term: L-alanine biosynthetic process from pyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate.


go_id: GO:0019273
term: L-alanine biosynthetic process via ornithine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine.


go_id: GO:0019276
term: UDP-N-acetylgalactosamine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.


go_id: GO:0019277
term: UDP-N-acetylgalactosamine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.


go_id: GO:0019278
term: UDP-N-acetylgalactosamine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.


go_id: GO:0019279
term: L-methionine biosynthetic process from L-homoserine via cystathionine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine.


go_id: GO:0019280
term: L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine.


go_id: GO:0019281
term: L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine.


go_id: GO:0019283
term: L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine.


go_id: GO:0019284
term: L-methionine biosynthetic process from S-adenosylmethionine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including S-adenosylmethionine.


go_id: GO:0019285
term: glycine betaine biosynthetic process from choline
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline.


go_id: GO:0019286
term: glycine betaine biosynthetic process from glycine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine.


go_id: GO:0019287
term: isopentenyl diphosphate biosynthetic process, mevalonate pathway
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.


go_id: GO:0019288
term: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.


go_id: GO:0019289
term: rhizobactin 1021 biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti.


go_id: GO:0019290
term: siderophore biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.


go_id: GO:0019292
term: tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate 4-hydroxyphenylpyruvate.


go_id: GO:0019293
term: tyrosine biosynthetic process, by oxidation of phenylalanine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of tyrosine by the oxidation of phenylalanine.


go_id: GO:0019294
term: keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.


go_id: GO:0019295
term: coenzyme M biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.


go_id: GO:0019296
term: coenzyme M metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.


go_id: GO:0019297
term: coenzyme B metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.


go_id: GO:0019298
term: coenzyme B biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.


go_id: GO:0019299
term: rhamnose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.


go_id: GO:0019300
term: rhamnose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose.


go_id: GO:0019301
term: rhamnose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.


go_id: GO:0019304
term: anaerobic rhamnose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose, that occurs in the absence of oxygen.


go_id: GO:0019305
term: dTDP-rhamnose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.


go_id: GO:0019306
term: GDP-D-rhamnose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.


go_id: GO:0019307
term: mannose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.


go_id: GO:0019308
term: dTDP-mannose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.


go_id: GO:0019309
term: mannose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.


go_id: GO:0019310
term: inositol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.


go_id: GO:0019311
term: sorbose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.


go_id: GO:0019312
term: L-sorbose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.


go_id: GO:0019313
term: allose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.


go_id: GO:0019314
term: D-allose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.


go_id: GO:0019315
term: D-allose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.


go_id: GO:0019316
term: D-allose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.


go_id: GO:0019318
term: hexose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.


go_id: GO:0019319
term: hexose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.


go_id: GO:0019320
term: hexose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.


go_id: GO:0019321
term: pentose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.


go_id: GO:0019322
term: pentose biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.


go_id: GO:0019323
term: pentose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.


go_id: GO:0019324
term: L-lyxose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose.


go_id: GO:0019325
term: anaerobic fructose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.


go_id: GO:0019326
term: nitrotoluene metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.


go_id: GO:0019328
term: anaerobic gallate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen.


go_id: GO:0019329
term: ammonia oxidation
ontology: BP
definition:
The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons.


go_id: GO:0019330
term: aldoxime metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH.


go_id: GO:0019331
term: anaerobic respiration, using ammonium as electron donor
ontology: BP
definition:
The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. It is suggested that hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2.


go_id: GO:0019332
term: aerobic respiration, using nitrite as electron donor
ontology: BP
definition:
The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species.


go_id: GO:0019333
term: denitrification pathway
ontology: BP
definition:
The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen.


go_id: GO:0019334
term: p-cymene catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.


go_id: GO:0019335
term: 3-methylquinoline catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.


go_id: GO:0019336
term: phenol-containing compound catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.


go_id: GO:0019337
term: tetrachloroethylene catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines.


go_id: GO:0019338
term: pentachlorophenol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.


go_id: GO:0019339
term: parathion catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.


go_id: GO:0019340
term: dibenzofuran catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond.


go_id: GO:0019341
term: dibenzo-p-dioxin catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds.


go_id: GO:0019342
term: trypanothione biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress.


go_id: GO:0019343
term: cysteine biosynthetic process via cystathionine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine.


go_id: GO:0019344
term: cysteine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.


go_id: GO:0019345
term: cysteine biosynthetic process via S-sulfo-L-cysteine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine.


go_id: GO:0019346
term: transsulfuration
ontology: BP
definition:
The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.


go_id: GO:0019347
term: GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.


go_id: GO:0019348
term: dolichol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.


go_id: GO:0019349
term: ribitol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin.


go_id: GO:0019350
term: teichoic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.


go_id: GO:0019351
term: dethiobiotin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms.


go_id: GO:0019352
term: protoporphyrinogen IX biosynthetic process from glycine
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine.


go_id: GO:0019353
term: protoporphyrinogen IX biosynthetic process from glutamate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate.


go_id: GO:0019355
term: nicotinamide nucleotide biosynthetic process from aspartate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including aspartate.


go_id: GO:0019356
term: nicotinate nucleotide biosynthetic process from tryptophan
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan.


go_id: GO:0019357
term: nicotinate nucleotide biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid).


go_id: GO:0019359
term: nicotinamide nucleotide biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.


go_id: GO:0019360
term: nicotinamide nucleotide biosynthetic process from niacinamide
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide.


go_id: GO:0019361
term: 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.


go_id: GO:0019362
term: pyridine nucleotide metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.


go_id: GO:0019363
term: pyridine nucleotide biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.


go_id: GO:0019364
term: pyridine nucleotide catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.


go_id: GO:0019365
term: pyridine nucleotide salvage
ontology: BP
definition:
Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis.


go_id: GO:0019369
term: arachidonic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.


go_id: GO:0019370
term: leukotriene biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.


go_id: GO:0019371
term: cyclooxygenase pathway
ontology: BP
definition:
The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.


go_id: GO:0019372
term: lipoxygenase pathway
ontology: BP
definition:
The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.


go_id: GO:0019373
term: epoxygenase P450 pathway
ontology: BP
definition:
The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.


go_id: GO:0019374
term: galactolipid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.


go_id: GO:0019375
term: galactolipid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.


go_id: GO:0019376
term: galactolipid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.


go_id: GO:0019377
term: glycolipid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).


go_id: GO:0019379
ontology: BP
term:
sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

definition:
The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).


go_id: GO:0019380
term: 3-phenylpropionate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid.


go_id: GO:0019381
term: atrazine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide.


go_id: GO:0019382
term: carbon tetrachloride catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.


go_id: GO:0019383
term: (+)-camphor catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone.


go_id: GO:0019384
term: caprolactam catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid.


go_id: GO:0019385
term: methanogenesis, from acetate
ontology: BP
definition:
The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate.


go_id: GO:0019386
term: methanogenesis, from carbon dioxide
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2).


go_id: GO:0019387
term: methanogenesis, from methanol
ontology: BP
definition:
The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol.


go_id: GO:0019388
term: galactose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.


go_id: GO:0019389
term: glucuronoside metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate.


go_id: GO:0019390
term: glucuronoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.


go_id: GO:0019391
term: glucuronoside catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.


go_id: GO:0019392
term: glucarate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate.


go_id: GO:0019393
term: glucarate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid.


go_id: GO:0019394
term: glucarate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid.


go_id: GO:0019395
term: fatty acid oxidation
ontology: BP
definition:
The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.


go_id: GO:0019396
term: gallate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).


go_id: GO:0019397
term: gallate catabolic process via 2-pyrone-4,6-dicarboxylate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate.


go_id: GO:0019398
term: gallate catabolic process via gallate dioxygenase activity
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase.


go_id: GO:0019400
term: alditol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.


go_id: GO:0019401
term: alditol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.


go_id: GO:0019402
term: galactitol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.


go_id: GO:0019403
term: galactitol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.


go_id: GO:0019404
term: galactitol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.


go_id: GO:0019405
term: alditol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.


go_id: GO:0019406
term: hexitol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule.


go_id: GO:0019407
term: hexitol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule.


go_id: GO:0019408
term: dolichol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.


go_id: GO:0019409
term: aerobic respiration, using ammonia as electron donor
ontology: BP
definition:
The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite.


go_id: GO:0019410
term: aerobic respiration, using carbon monoxide as electron donor
ontology: BP
definition:
The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation.


go_id: GO:0019411
term: aerobic respiration, using ferrous ions as electron donor
ontology: BP
definition:
The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide.


go_id: GO:0019412
term: aerobic respiration, using hydrogen as electron donor
ontology: BP
definition:
The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water.


go_id: GO:0019413
term: acetate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.


go_id: GO:0019414
term: aerobic respiration, using sulfur or sulfate as electron donor
ontology: BP
definition:
An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized.


go_id: GO:0019415
term: acetate biosynthetic process from carbon monoxide
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of acetate from other compounds, including carbon monoxide.


go_id: GO:0019416
term: polythionate oxidation
ontology: BP
definition:
The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor.


go_id: GO:0019418
term: sulfide oxidation
ontology: BP
definition:
The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate.


go_id: GO:0019419
term: sulfate reduction
ontology: BP
definition:
The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.


go_id: GO:0019420
term: dissimilatory sulfate reduction
ontology: BP
definition:
The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide.


go_id: GO:0019422
term: disproportionation of elemental sulfur
ontology: BP
definition:
The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2.


go_id: GO:0019423
term: sulfur oxidation, ferric ion-dependent
ontology: BP
definition:
A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+).


go_id: GO:0019426
term: bisulfite reduction
ontology: BP
definition:
The chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite.


go_id: GO:0019427
term: acetyl-CoA biosynthetic process from acetate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate.


go_id: GO:0019428
term: allantoin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.


go_id: GO:0019429
term: fluorene catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.


go_id: GO:0019430
term: removal of superoxide radicals
ontology: BP
definition:
Any process involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).


go_id: GO:0019431
term: acetyl-CoA biosynthetic process from ethanol
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of acetyl-CoA from ethanol via acetaldehyde.


go_id: GO:0019432
term: triglyceride biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.


go_id: GO:0019433
term: triglyceride catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.


go_id: GO:0019434
term: sophorosyloxydocosanoate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon.


go_id: GO:0019435
term: sophorosyloxydocosanoate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.


go_id: GO:0019436
term: sophorosyloxydocosanoate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.


go_id: GO:0019438
term: aromatic compound biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.


go_id: GO:0019439
term: aromatic compound catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.


go_id: GO:0019440
term: tryptophan catabolic process to indole-3-acetate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate.


go_id: GO:0019441
term: tryptophan catabolic process to kynurenine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.


go_id: GO:0019442
term: tryptophan catabolic process to acetyl-CoA
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA.


go_id: GO:0019444
term: tryptophan catabolic process to catechol
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol.


go_id: GO:0019445
term: tyrosine catabolic process to fumarate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate.


go_id: GO:0019446
term: tyrosine catabolic process to phosphoenolpyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including phosphoenolpyruvate.


go_id: GO:0019447
term: D-cysteine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.


go_id: GO:0019448
term: L-cysteine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.


go_id: GO:0019449
term: L-cysteine catabolic process to hypotaurine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine.


go_id: GO:0019450
term: L-cysteine catabolic process to pyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate.


go_id: GO:0019451
term: L-cysteine catabolic process to pyruvate, using cysteine dioxygenase
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20).


go_id: GO:0019452
term: L-cysteine catabolic process to taurine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine.


go_id: GO:0019453
term: L-cysteine catabolic process via cystine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine.


go_id: GO:0019454
term: L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase (EC:1.8.4.4).


go_id: GO:0019455
term: L-cysteine catabolic process via cystine, using cystine reductase
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase (EC:1.8.1.6).


go_id: GO:0019456
term: L-cysteine catabolic process via cystine, using cysteine transaminase
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase (EC:2.6.1.3).


go_id: GO:0019457
term: methionine catabolic process to succinyl-CoA
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of methionine into other compounds, including succinyl-CoA.


go_id: GO:0019458
term: methionine catabolic process via 2-oxobutanoate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate.


go_id: GO:0019460
term: glutamine catabolic process to fumarate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate.


go_id: GO:0019461
term: glutamine catabolic process to fumarate, using glutamate synthase (NADPH)
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13).


go_id: GO:0019462
term: glutamine catabolic process to fumarate, using glutaminase
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2).


go_id: GO:0019463
term: glycine catabolic process to creatine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine.


go_id: GO:0019465
term: aspartate transamidation
ontology: BP
definition:
The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group.


go_id: GO:0019466
term: ornithine catabolic process via proline
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline.


go_id: GO:0019468
term: nopaline catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.


go_id: GO:0019469
term: octopine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of octopine (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.


go_id: GO:0019470
term: 4-hydroxyproline catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.


go_id: GO:0019471
term: 4-hydroxyproline metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls.


go_id: GO:0019472
term: 4-hydroxyproline biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.


go_id: GO:0019473
term: L-lysine catabolic process to glutarate, by acetylation
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation.


go_id: GO:0019474
term: L-lysine catabolic process to acetyl-CoA
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA.


go_id: GO:0019475
term: L-lysine catabolic process to acetate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate.


go_id: GO:0019476
term: D-lysine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.


go_id: GO:0019477
term: L-lysine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid.


go_id: GO:0019478
term: D-amino acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids.


go_id: GO:0019479
term: L-alanine oxidation to D-lactate and ammonia
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia.


go_id: GO:0019480
term: L-alanine oxidation to pyruvate via D-alanine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate.


go_id: GO:0019482
term: beta-alanine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.


go_id: GO:0019483
term: beta-alanine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.


go_id: GO:0019484
term: beta-alanine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.


go_id: GO:0019485
term: beta-alanine catabolic process to L-alanine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including L-alanine.


go_id: GO:0019486
term: beta-alanine catabolic process to mevalonate semialdehyde, by transamination
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination.


go_id: GO:0019487
term: anaerobic acetylene catabolic process
ontology: BP
definition:
The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen.


go_id: GO:0019488
term: ribitol catabolic process to xylulose 5-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. Ribitol is initially converted to D-ribulose, which is phosphorylated to form ribulose 5-phosphate, which is then converted into xylulose 5-phosphate.


go_id: GO:0019489
term: methylgallate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.


go_id: GO:0019490
term: 2-aminobenzenesulfonate desulfonation
ontology: BP
definition:
The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.


go_id: GO:0019491
term: ectoine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.


go_id: GO:0019492
term: proline salvage
ontology: BP
definition:
Any process which produces the amino acid proline from derivatives of it, without de novo synthesis.


go_id: GO:0019493
term: arginine catabolic process to proline
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline.


go_id: GO:0019495
term: proline catabolic process to 2-oxoglutarate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate.


go_id: GO:0019496
term: serine-isocitrate lyase pathway
ontology: BP
definition:
A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide.


go_id: GO:0019497
term: hexachlorocyclohexane metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution.


go_id: GO:0019499
term: cyanide metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain.


go_id: GO:0019500
term: cyanide catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.


go_id: GO:0019501
term: arsonoacetate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom.


go_id: GO:0019502
term: stachydrine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants.


go_id: GO:0019503
term: stachydrine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.


go_id: GO:0019504
term: stachydrine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.


go_id: GO:0019505
term: resorcinol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic.


go_id: GO:0019506
term: phenylmercury acetate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.


go_id: GO:0019507
term: pyridine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.


go_id: GO:0019508
term: 2,5-dihydroxypyridine catabolic process to fumarate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate.


go_id: GO:0019510
term: S-adenosylhomocysteine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine.


go_id: GO:0019512
term: lactose catabolic process via tagatose-6-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate.


go_id: GO:0019513
term: lactose catabolic process, using glucoside 3-dehydrogenase
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase (EC:1.1.99.13).


go_id: GO:0019515
term: lactose catabolic process via UDP-galactose
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose.


go_id: GO:0019516
term: lactate oxidation
ontology: BP
definition:
The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons.


go_id: GO:0019517
term: L-threonine catabolic process to D-lactate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate.


go_id: GO:0019518
term: L-threonine catabolic process to glycine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine.


go_id: GO:0019519
term: pentitol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule.


go_id: GO:0019520
term: aldonic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.


go_id: GO:0019521
term: D-gluconate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.


go_id: GO:0019522
term: ketogluconate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.


go_id: GO:0019523
term: L-idonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.


go_id: GO:0019524
term: keto-D-gluconate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.


go_id: GO:0019525
term: keto-D-gluconate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.


go_id: GO:0019526
term: pentitol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule.


go_id: GO:0019527
term: pentitol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule.


go_id: GO:0019528
term: D-arabitol catabolic process to xylulose 5-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.


go_id: GO:0019529
term: taurine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.


go_id: GO:0019530
term: taurine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.


go_id: GO:0019531
term: oxalate transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of oxalate from one side of the membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.


go_id: GO:0019532
term: oxalate transport
ontology: BP
definition:
The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.


go_id: GO:0019533
term: cellobiose transport
ontology: BP
definition:
The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.


go_id: GO:0019534
term: toxin transporter activity
ontology: MF
definition:
Enables the directed movement of a toxin into, out of or within a cell, or between cells. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.


go_id: GO:0019536
term: vibriobactin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae.


go_id: GO:0019537
term: vibriobactin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae.


go_id: GO:0019538
term: protein metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.


go_id: GO:0019539
term: siderophore biosynthetic process from hydroxamic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid.


go_id: GO:0019540
term: siderophore biosynthetic process from catechol
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol.


go_id: GO:0019541
term: propionate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants.


go_id: GO:0019542
term: propionate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid.


go_id: GO:0019543
term: propionate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid.


go_id: GO:0019544
term: arginine catabolic process to glutamate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.


go_id: GO:0019545
term: arginine catabolic process to succinate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate.


go_id: GO:0019546
term: arginine deiminase pathway
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.


go_id: GO:0019547
term: arginine catabolic process to ornithine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine.


go_id: GO:0019548
term: arginine catabolic process to spermine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine.


go_id: GO:0019549
term: glutamate catabolic process to succinate via succinate semialdehyde
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the pyruvate-dependent gamma aminobutyrate (GABA) transaminase.


go_id: GO:0019550
term: glutamate catabolic process to aspartate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate.


go_id: GO:0019551
term: glutamate catabolic process to 2-oxoglutarate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate.


go_id: GO:0019552
term: glutamate catabolic process via 2-hydroxyglutarate
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP.


go_id: GO:0019553
term: glutamate catabolic process via L-citramalate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate.


go_id: GO:0019554
term: glutamate catabolic process to oxaloacetate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate.


go_id: GO:0019555
term: glutamate catabolic process to ornithine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine.


go_id: GO:0019556
term: histidine catabolic process to glutamate and formamide
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide.


go_id: GO:0019557
term: histidine catabolic process to glutamate and formate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate.


go_id: GO:0019558
term: histidine catabolic process to 2-oxoglutarate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate.


go_id: GO:0019559
term: histidine catabolic process to imidazol-5-yl-lactate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including imidazol-5-yl-lactate.


go_id: GO:0019560
term: histidine catabolic process to hydantoin-5-propionate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate.


go_id: GO:0019561
term: anaerobic phenylalanine oxidation
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde.


go_id: GO:0019562
term: phenylalanine catabolic process to phosphoenolpyruvate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phenylalanine into other compounds, including phosphoenolpyruvate.


go_id: GO:0019563
term: glycerol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.


go_id: GO:0019564
term: aerobic glycerol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen.


go_id: GO:0019566
term: arabinose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides.


go_id: GO:0019569
term: L-arabinose catabolic process to xylulose 5-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate.


go_id: GO:0019570
term: L-arabinose catabolic process to 2-oxoglutarate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate.


go_id: GO:0019571
term: D-arabinose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose.


go_id: GO:0019572
term: L-arabinose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose.


go_id: GO:0019573
term: D-arabinose catabolic process to xylulose 5-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-arabinose to form xylulose 5-phosphate. D-arabinose is converted into D-ribulose, which is phosphorylated to ribulose-5-phosphate, which is isomerized to give D-xylulose-5-phosphate.


go_id: GO:0019574
term: sucrose catabolic process via 3'-ketosucrose
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose.


go_id: GO:0036008
term: sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate.


go_id: GO:0019576
term: aerobic fructose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the presence of oxygen.


go_id: GO:0019577
term: aldaric acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.


go_id: GO:0019578
term: aldaric acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.


go_id: GO:0019579
term: aldaric acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.


go_id: GO:0019580
term: galactarate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose.


go_id: GO:0019583
term: galactonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose.


go_id: GO:0019584
term: galactonate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of galactonate, the anion of galactonic acid.


go_id: GO:0019585
term: glucuronate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.


go_id: GO:0019586
term: galacturonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving galacturonate, the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.


go_id: GO:0019588
term: anaerobic glycerol catabolic process
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP.


go_id: GO:0019589
term: anaerobic glycerol catabolic process to propane-1,3-diol
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water.


go_id: GO:0019590
term: L-arabitol catabolic process to xylulose 5-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-arabitol to form xylulose 5-phosphate. L-arabitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.


go_id: GO:0019592
term: mannitol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.


go_id: GO:0019593
term: mannitol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.


go_id: GO:0019594
term: mannitol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.


go_id: GO:0019595
term: non-phosphorylated glucose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose.


go_id: GO:0019596
term: mandelate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.


go_id: GO:0019597
term: (R)-mandelate catabolic process to benzoate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate.


go_id: GO:0019598
term: (R)-mandelate catabolic process to catechol
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including catechol.


go_id: GO:0019599
term: (R)-4-hydroxymandelate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid.


go_id: GO:0019600
term: toluene oxidation
ontology: BP
definition:
The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene.


go_id: GO:0019601
term: toluene oxidation via 2-hydroxytoluene
ontology: BP
definition:
The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol).


go_id: GO:0019602
term: toluene oxidation via 3-hydroxytoluene
ontology: BP
definition:
The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol).


go_id: GO:0019603
term: toluene oxidation via 4-hydroxytoluene
ontology: BP
definition:
The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol).


go_id: GO:0019604
term: toluene oxidation to catechol
ontology: BP
definition:
The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2).


go_id: GO:0019605
term: butyrate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.


go_id: GO:0019606
term: 2-oxobutyrate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.


go_id: GO:0019607
term: phenylethylamine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.


go_id: GO:0019608
term: nicotine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.


go_id: GO:0019609
term: 3-hydroxyphenylacetate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.


go_id: GO:0019610
term: 3-hydroxyphenylacetate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.


go_id: GO:0019611
term: 4-toluenecarboxylate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.


go_id: GO:0019612
term: 4-toluenecarboxylate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.


go_id: GO:0019614
term: catechol-containing compound catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.


go_id: GO:0019615
term: catechol catabolic process, ortho-cleavage
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups.


go_id: GO:0019616
term: catechol catabolic process, meta-cleavage
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom.


go_id: GO:0019617
term: protocatechuate catabolic process, meta-cleavage
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate.


go_id: GO:0019618
term: protocatechuate catabolic process, ortho-cleavage
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate.


go_id: GO:0019619
term: protocatechuate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid.


go_id: GO:0019620
term: aerobic benzoate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen.


go_id: GO:0019621
term: creatinine catabolic process to formate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate.


go_id: GO:0019622
term: 3-(3-hydroxy)phenylpropionate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.


go_id: GO:0019623
term: atrazine catabolic process to urea
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into urea.


go_id: GO:0019624
term: atrazine catabolic process to isopropylamine
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine.


go_id: GO:0019625
term: atrazine catabolic process to cyanuric acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid.


go_id: GO:0019626
term: short-chain fatty acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6.


go_id: GO:0019628
term: urate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine.


go_id: GO:0019629
term: propionate catabolic process, 2-methylcitrate cycle
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.


go_id: GO:0019630
term: quinate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine.


go_id: GO:0019631
term: quinate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.


go_id: GO:0019632
term: shikimate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids.


go_id: GO:0019633
term: shikimate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.


go_id: GO:0019634
term: organic phosphonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.


go_id: GO:0019635
term: 2-aminoethylphosphonate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine.


go_id: GO:0019636
term: phosphonoacetate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue.


go_id: GO:0019637
term: organophosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.


go_id: GO:0019638
term: 6-hydroxycineole metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.


go_id: GO:0019639
term: 6-hydroxycineole catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.


go_id: GO:0019640
term: glucuronate catabolic process to xylulose 5-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate.


go_id: GO:0019643
term: reductive tricarboxylic acid cycle
ontology: BP
definition:
A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate.


go_id: GO:0019645
term: anaerobic electron transport chain
ontology: BP
definition:
A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient.


go_id: GO:0019646
term: aerobic electron transport chain
ontology: BP
definition:
A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient.


go_id: GO:0019647
term: formaldehyde assimilation via ribulose monophosphate cycle
ontology: BP
definition:
The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde.


go_id: GO:0019648
term: formaldehyde assimilation via xylulose monophosphate cycle
ontology: BP
definition:
The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds.


go_id: GO:0019650
term: glycolytic fermentation to butanediol
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.


go_id: GO:0019651
term: citrate catabolic process to diacetyl
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP.


go_id: GO:0019652
term: lactate fermentation to propionate and acetate
ontology: BP
definition:
The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP).


go_id: GO:0019653
term: anaerobic purine nucleobase catabolic process
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP.


go_id: GO:0019654
term: acetate fermentation
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP.


go_id: GO:0019655
term: glycolytic fermentation to ethanol
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose.


go_id: GO:0019656
term: glucose catabolic process to D-lactate and ethanol
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule.


go_id: GO:0019657
term: glycolytic fermentation to propionate
ontology: BP
definition:
Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate.


go_id: GO:0019658
term: glucose fermentation to lactate and acetate
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP.


go_id: GO:0019659
term: glucose catabolic process to lactate
ontology: BP
definition:
The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP).


go_id: GO:0019660
term: glycolytic fermentation
ontology: BP
definition:
Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.


go_id: GO:0019661
term: glucose catabolic process to lactate via pyruvate
ontology: BP
definition:
The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP).


go_id: GO:0019662
term: non-glycolytic fermentation
ontology: BP
definition:
Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.


go_id: GO:0019664
term: mixed acid fermentation
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into ethanol, lactate, formate, succinate, and acetate, yielding energy in the form of ATP.


go_id: GO:0019665
term: anaerobic amino acid catabolic process
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP.


go_id: GO:0019666
term: nitrogenous compound fermentation
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP.


go_id: GO:0019667
term: anaerobic L-alanine catabolic process
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP.


go_id: GO:0019668
term: anaerobic catabolism of pairs of amino acids
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP.


go_id: GO:0019669
term: anaerobic glycine catabolic process
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP.


go_id: GO:0019670
term: anaerobic glutamate catabolic process
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, yielding energy in the form of ATP.


go_id: GO:0019671
term: glutamate catabolic process via mesaconate and citramalate
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate via the intermediates mesaconate and S-citramalate, yielding energy in the form of ATP.


go_id: GO:0019672
term: ethanol-acetate fermentation to butyrate and caproate
ontology: BP
definition:
The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP.


go_id: GO:0019673
term: GDP-mannose metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.


go_id: GO:0019674
term: NAD metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.


go_id: GO:0019676
term: ammonia assimilation cycle
ontology: BP
definition:
The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.


go_id: GO:0019677
term: NAD catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH.


go_id: GO:0019680
term: L-methylmalonyl-CoA biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA.


go_id: GO:0019681
term: acetyl-CoA assimilation pathway
ontology: BP
definition:
The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell.


go_id: GO:0019682
term: glyceraldehyde-3-phosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis.


go_id: GO:0019683
term: glyceraldehyde-3-phosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.


go_id: GO:0019684
term: photosynthesis, light reaction
ontology: BP
definition:
The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I.


go_id: GO:0019685
term: photosynthesis, dark reaction
ontology: BP
definition:
A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions.


go_id: GO:0019686
term: purine nucleoside interconversion
ontology: BP
definition:
The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside.


go_id: GO:0019687
term: pyruvate biosynthetic process from acetate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate.


go_id: GO:0019688
term: purine deoxyribonucleoside interconversion
ontology: BP
definition:
The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside.


go_id: GO:0019689
term: pyrimidine nucleoside interconversion
ontology: BP
definition:
The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside.


go_id: GO:0019690
term: pyrimidine deoxyribonucleoside interconversion
ontology: BP
definition:
The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside.


go_id: GO:0019692
term: deoxyribose phosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.


go_id: GO:0019694
term: alkanesulfonate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.


go_id: GO:0019695
term: choline metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.


go_id: GO:0019696
term: toluene oxidation via toluene-cis-1,2-dihydrodiol
ontology: BP
definition:
The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol.


go_id: GO:0019697
term: L-xylitol catabolic process to xylulose 5-phosphate
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.


go_id: GO:0019698
term: D-galacturonate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.


go_id: GO:0019700
term: organic phosphonate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.


go_id: GO:0019701
term: peptidyl-arginine N5-methylation
ontology: BP
definition:
The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine.


go_id: GO:0019702
term: protein-arginine N5-methyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues.


go_id: GO:0019705
term: protein-cysteine S-myristoyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a myristoyl group to a sulfur atom on a cysteine residue of a protein molecule.


go_id: GO:0019706
term: protein-cysteine S-palmitoyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a palmitoyl group to a sulfur atom on the cysteine of a protein molecule.


go_id: GO:0019708
term: peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine
ontology: BP
definition:
The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins.


go_id: GO:0019709
ontology: BP
term:
iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide

definition:
The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.


go_id: GO:0019710
term: peptidyl-asparagine methylation
ontology: BP
definition:
The methylation of peptidyl-asparagine to form peptidyl-N4-methyl-L-asparagine or peptidyl-N4,N4-dimethyl-L-asparagine.


go_id: GO:0019711
term: peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid.


go_id: GO:0019715
term: peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid
ontology: BP
definition:
The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).


go_id: GO:0019716
term: N-terminal peptidyl-alanine monomethylation
ontology: BP
definition:
The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine.


go_id: GO:0019720
term: Mo-molybdopterin cofactor metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.


go_id: GO:0019724
term: B cell mediated immunity
ontology: BP
definition:
Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.


go_id: GO:0019729
term: peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine
ontology: BP
definition:
The formation of the fluorescent protein FP583 chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.


go_id: GO:0019731
term: antibacterial humoral response
ontology: BP
definition:
An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.


go_id: GO:0019732
term: antifungal humoral response
ontology: BP
definition:
An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster.


go_id: GO:0019740
term: nitrogen utilization
ontology: BP
definition:
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.


go_id: GO:0019741
term: pentacyclic triterpenoid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.


go_id: GO:0019742
term: pentacyclic triterpenoid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.


go_id: GO:0019743
term: hopanoid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.


go_id: GO:0019744
term: hopanoid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.


go_id: GO:0019745
term: pentacyclic triterpenoid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.


go_id: GO:0019746
term: hopanoid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.


go_id: GO:0019747
term: regulation of isoprenoid metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.


go_id: GO:0019748
term: secondary metabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.


go_id: GO:0019749
term: cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte
ontology: BP
definition:
The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.


go_id: GO:0019750
term: chloroplast localization
ontology: BP
definition:
Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants.


go_id: GO:0019751
term: polyol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.


go_id: GO:0019752
term: carboxylic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).


go_id: GO:0019755
term: one-carbon compound transport
ontology: BP
definition:
The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0019756
term: cyanogenic glycoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.


go_id: GO:0019757
term: glycosinolate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.


go_id: GO:0019758
term: glycosinolate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.


go_id: GO:0019759
term: glycosinolate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.


go_id: GO:0019760
term: glucosinolate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.


go_id: GO:0019761
term: glucosinolate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.


go_id: GO:0019762
term: glucosinolate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.


go_id: GO:0019763
term: immunoglobulin receptor activity
ontology: MF
definition:
Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019768
term: high-affinity IgE receptor activity
ontology: MF
definition:
Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019771
term: high-affinity IgG receptor activity
ontology: MF
definition:
Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019769
term: low-affinity IgE receptor activity
ontology: MF
definition:
Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019772
term: low-affinity IgG receptor activity
ontology: MF
definition:
Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019766
term: IgA receptor activity
ontology: MF
definition:
Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019767
term: IgE receptor activity
ontology: MF
definition:
Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019770
term: IgG receptor activity
ontology: MF
definition:
Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0019773
term: proteasome core complex, alpha-subunit complex
ontology: CC
definition:
The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.


go_id: GO:0019774
term: proteasome core complex, beta-subunit complex
ontology: CC
definition:
The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.


go_id: GO:0019775
term: FAT10 transferase activity
ontology: MF
definition:
Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y --> Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages.


go_id: GO:0019776
term: Atg8 ligase activity
ontology: MF
definition:
Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate.


go_id: GO:0019777
term: Atg12 transferase activity
ontology: MF
definition:
Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.


go_id: GO:0019778
term: Atg12 activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0019779
term: Atg8 activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0019780
term: FAT10 activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0019782
term: ISG15 activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0019783
term: ubiquitin-like protein-specific protease activity
ontology: MF
definition:
Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated.


go_id: GO:0019784
term: NEDD8-specific protease activity
ontology: MF
definition:
Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates.


go_id: GO:0019785
term: ISG15-specific protease activity
ontology: MF
definition:
Catalysis of the hydrolysis of ISG15, a small ubiquitin-related modifier, from previously modified substrates.


go_id: GO:0019787
term: ubiquitin-like protein transferase activity
ontology: MF
definition:
Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.


go_id: GO:0019788
term: NEDD8 transferase activity
ontology: MF
definition:
Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y --> Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.


go_id: GO:0019789
term: SUMO transferase activity
ontology: MF
definition:
Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.


go_id: GO:0019797
term: procollagen-proline 3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.


go_id: GO:0019798
term: procollagen-proline dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.


go_id: GO:0019799
term: tubulin N-acetyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine.


go_id: GO:0019800
term: peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
ontology: BP
definition:
The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain.


go_id: GO:0019801
term: cyclization of asparagine involved in intein-mediated protein splicing
ontology: BP
definition:
The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing.


go_id: GO:0019802
term: cyclization of glutamine involved in intein-mediated protein splicing
ontology: BP
definition:
The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing.


go_id: GO:0019805
term: quinolinate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.


go_id: GO:0019806
term: bromide peroxidase activity
ontology: MF
definition:
Catalysis of the reaction: 2 R-H + 2 bromide + hydrogen peroxide = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.


go_id: GO:0019808
term: polyamine binding
ontology: MF
definition:
Interacting selectively and non-covalently with polyamines, organic compounds containing two or more amino groups.


go_id: GO:0019810
term: putrescine binding
ontology: MF
definition:
Interacting selectively and non-covalently with putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.


go_id: GO:0019811
term: cocaine binding
ontology: MF
definition:
Interacting selectively and non-covalently with cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis.


go_id: GO:0019812
term: Type I site-specific deoxyribonuclease complex
ontology: CC
definition:
A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell.


go_id: GO:0019813
term: Type III site-specific deoxyribonuclease complex
ontology: CC
definition:
A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.


go_id: GO:0019814
term: immunoglobulin complex
ontology: CC
definition:
A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0019815
term: B cell receptor complex
ontology: CC
definition:
An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


go_id: GO:0019819
term: P1 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms.


go_id: GO:0019820
term: P2 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed.


go_id: GO:0019821
term: P3 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content.


go_id: GO:0019822
term: P4 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.


go_id: GO:0019823
term: P5 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.


go_id: GO:0019824
term: P6 peroxisome
ontology: CC
definition:
A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes.


go_id: GO:0019826
term: oxygen sensor activity
ontology: MF
definition:
Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).


go_id: GO:0019827
term: stem cell population maintenance
ontology: BP
definition:
The process by which an organism or tissue maintains a population of stem cells of a single type.  This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.


go_id: GO:0019828
term: aspartic-type endopeptidase inhibitor activity
ontology: MF
definition:
Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.


go_id: GO:0046686
term: response to cadmium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.


go_id: GO:0046687
term: response to chromate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.


go_id: GO:0046689
term: response to mercury ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.


go_id: GO:0019840
term: isoprenoid binding
ontology: MF
definition:
Interacting selectively and non-covalently with any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.


go_id: GO:0019841
term: retinol binding
ontology: MF
definition:
Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.


go_id: GO:0019842
term: vitamin binding
ontology: MF
definition:
Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.


go_id: GO:0046929
term: negative regulation of neurotransmitter secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.


go_id: GO:0019852
term: L-ascorbic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.


go_id: GO:0019853
term: L-ascorbic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.


go_id: GO:0019854
term: L-ascorbic acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.


go_id: GO:0019856
term: pyrimidine nucleobase biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.


go_id: GO:0019858
term: cytosine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.


go_id: GO:0019859
term: thymine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.


go_id: GO:0019860
term: uracil metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.


go_id: GO:0019866
term: organelle inner membrane
ontology: CC
definition:
The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.


go_id: GO:0019867
term: outer membrane
ontology: CC
definition:
The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.


go_id: GO:0019872
term: streptomycin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


go_id: GO:0046690
term: response to tellurium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.


go_id: GO:0019874
term: 6-aminohexanoate-cyclic-dimer hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate.


go_id: GO:0019876
term: nylon catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.


go_id: GO:0019877
term: diaminopimelate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.


go_id: GO:0019878
term: lysine biosynthetic process via aminoadipic acid
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.


go_id: GO:0019879
term: peptidyl-thyronine biosynthetic process from peptidyl-tyrosine
ontology: BP
definition:
The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine.


go_id: GO:0046678
term: response to bacteriocin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.


go_id: GO:0046679
term: response to streptomycin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


go_id: GO:0019882
term: antigen processing and presentation
ontology: BP
definition:
The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


go_id: GO:0019883
term: antigen processing and presentation of endogenous antigen
ontology: BP
definition:
The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.


go_id: GO:0019884
term: antigen processing and presentation of exogenous antigen
ontology: BP
definition:
The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex.


go_id: GO:0019885
term: antigen processing and presentation of endogenous peptide antigen via MHC class I
ontology: BP
definition:
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.


go_id: GO:0019886
term: antigen processing and presentation of exogenous peptide antigen via MHC class II
ontology: BP
definition:
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.


go_id: GO:0019888
term: protein phosphatase regulator activity
ontology: MF
definition:
Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.


go_id: GO:0019889
term: pteridine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.


go_id: GO:0019894
term: kinesin binding
ontology: MF
definition:
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.


go_id: GO:0019895
term: kinesin-associated mitochondrial adaptor activity
ontology: MF
definition:
The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria.


go_id: GO:0019897
term: extrinsic component of plasma membrane
ontology: CC
definition:
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


go_id: GO:0019900
term: kinase binding
ontology: MF
definition:
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.


go_id: GO:0019901
term: protein kinase binding
ontology: MF
definition:
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.


go_id: GO:0019905
term: syntaxin binding
ontology: MF
definition:
Interacting selectively and non-covalently with a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse.


go_id: GO:0019907
term: cyclin-dependent protein kinase activating kinase holoenzyme complex
ontology: CC
definition:
A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases by threonine phosphorylation, thus regulating cell cycle progression. consists of a kinase, cyclin and optional assembly factors, in human CDK7, CCNH and MNAT1. CAK activity is itself regulated throughout the cell cycle by T-loop phosphorylation of its kinase component (CDK7 in human). Phosphorylation of serine residues during mitosis inactivates the enzyme. Also capable of CAK phosphorylating the carboxyl-terminal domain (CTD) of RNA polymerase II and other transcription activating proteins, as part of the general transcription factor TFIIH.


go_id: GO:0019910
term: mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex
ontology: CC
definition:
A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus.


go_id: GO:0019911
term: structural constituent of myelin sheath
ontology: MF
definition:
The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve.


go_id: GO:0019912
term: cyclin-dependent protein kinase activating kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK).


go_id: GO:0019915
term: lipid storage
ontology: BP
definition:
The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.


go_id: GO:0019918
term: peptidyl-arginine methylation, to symmetrical-dimethyl arginine
ontology: BP
definition:
The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine.


go_id: GO:0019919
term: peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
ontology: BP
definition:
The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.


go_id: GO:0019920
term: peptidyl-1-thioglycine biosynthetic process, internal
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide.


go_id: GO:0019921
term: peptidyl-1-thioglycine biosynthetic process, carboxy-terminal
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond.


go_id: GO:0019923
term: alpha-1-microglobulin-chromophore linkage
ontology: BP
definition:
The covalent linking of the alpha-1-microglobulin chromophore to the protein; the structure of the chromophore is not known. It is probably heterogeneous and involving two cysteines in thioether bonds.


go_id: GO:0019926
term: peptidyl-tryptophan oxidation to tryptophyl quinone
ontology: BP
definition:
The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine.


go_id: GO:0019927
term: peptide cross-linking via 4'-(S-L-cysteinyl)-L-tryptophyl quinone
ontology: BP
definition:
The cross-linking of a cysteine residue to tryptophyl quinone to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone, a cofactor found at the active site of amine dehydrogenase.


go_id: GO:0019928
term: peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid
ontology: BP
definition:
The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid.


go_id: GO:0019929
term: peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid
ontology: BP
definition:
The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid.


go_id: GO:0019930
ontology: BP
term:
cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid

definition:
The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1.


go_id: GO:0019932
term: second-messenger-mediated signaling
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell.


go_id: GO:0019933
term: cAMP-mediated signaling
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.


go_id: GO:0019934
term: cGMP-mediated signaling
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.


go_id: GO:0019935
term: cyclic-nucleotide-mediated signaling
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell.


go_id: GO:0048016
term: inositol phosphate-mediated signaling
ontology: BP
definition:
Any intracellular signal transduction in which the signal is passed on within the cell via an inositol phosphate. Includes production of the inositol phosphate, and downstream effectors that further transmit the signal within the cell. Inositol phosphates are a group of mono- to poly-phosphorylated inositols, and include inositol monophosphate (IP), inositol trisphosphate (IP3), inositol pentakisphosphate (IP5) and inositol hexaphosphate (IP6).


go_id: GO:0048017
term: inositol lipid-mediated signaling
ontology: BP
definition:
A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids.


go_id: GO:0019937
term: protein catenane formation via N6-(L-isoaspartyl)-L-lysine, autocatalytic
ontology: BP
definition:
The autocatalytic formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; known to occur in the capsid of some bacteriophage, such as HK97, where it is thought to provide a mechanism for stabilizing the capsid.


go_id: GO:0019938
term: peptide cross-linking via N6-(L-isoaspartyl)-L-lysine, presumed catalytic
ontology: BP
definition:
The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; occurs in mammals in proteins as yet unidentified by a mechanism probably analogous to that of transglutaminase reactions.


go_id: GO:0019948
term: SUMO activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0019950
term: SMT3-dependent protein catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein SMT3 to the target protein.


go_id: GO:0019953
term: sexual reproduction
ontology: BP
definition:
A reproduction process that creates a new organism by combining the genetic material of two organisms. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two different individuals (parents) join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.


go_id: GO:0019954
term: asexual reproduction
ontology: BP
definition:
The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process.


go_id: GO:0019955
term: cytokine binding
ontology: MF
definition:
Interacting selectively and non-covalently with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.


go_id: GO:0019956
term: chemokine binding
ontology: MF
definition:
Interacting selectively and non-covalently with a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.


go_id: GO:0019957
term: C-C chemokine binding
ontology: MF
definition:
Interacting selectively and non-covalently with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.


go_id: GO:0019958
term: C-X-C chemokine binding
ontology: MF
definition:
Interacting selectively and non-covalently with a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.


go_id: GO:0019960
term: C-X3-C chemokine binding
ontology: MF
definition:
Interacting selectively and non-covalently with a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.


go_id: GO:0019961
term: interferon binding
ontology: MF
definition:
Interacting selectively and non-covalently with an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent.


go_id: GO:0019962
term: type I interferon binding
ontology: MF
definition:
Interacting selectively and non-covalently with a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0019964
term: interferon-gamma binding
ontology: MF
definition:
Interacting selectively and non-covalently with interferon-gamma. Interferon gamma is the only member of the type II interferon found so far.


go_id: GO:0019975
term: interleukin-17 binding
ontology: MF
definition:
Interacting selectively and non-covalently with any member of the interleukin-17 family of cytokines.


go_id: GO:0019985
term: translesion synthesis
ontology: BP
definition:
The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.


go_id: GO:0019988
term: charged-tRNA amino acid modification
ontology: BP
definition:
The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine.


go_id: GO:0019990
term: pteridine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.


go_id: GO:0019991
term: septate junction assembly
ontology: BP
definition:
The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.


go_id: GO:0019992
term: diacylglycerol binding
ontology: MF
definition:
Interacting selectively and non-covalently with diacylglycerol, a diester of glycerol and two fatty acids.


go_id: GO:0020003
term: symbiont-containing vacuole
ontology: CC
definition:
Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont.


go_id: GO:0020005
term: symbiont-containing vacuole membrane
ontology: CC
definition:
The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont.


go_id: GO:0020006
term: symbiont-containing vacuolar membrane network
ontology: CC
definition:
Tubular network of extensions from the symbiont-containing vacuole membrane that protrude into the host cytoplasm.


go_id: GO:0020007
term: apical complex
ontology: CC
definition:
A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation.


go_id: GO:0020008
term: rhoptry
ontology: CC
definition:
A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the parasitophorous vacuole.


go_id: GO:0020009
term: microneme
ontology: CC
definition:
A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell.


go_id: GO:0020010
term: conoid
ontology: CC
definition:
A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules.


go_id: GO:0020012
term: evasion or tolerance of host immune response
ontology: BP
definition:
Any process, either active or passive, by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0020013
term: modulation by symbiont of host erythrocyte aggregation
ontology: BP
definition:
Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.


go_id: GO:0020014
term: schizogony
ontology: BP
definition:
Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.


go_id: GO:0020015
term: glycosome
ontology: CC
definition:
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.


go_id: GO:0020020
term: food vacuole
ontology: CC
definition:
Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa.


go_id: GO:0020021
term: immortalization of host cell
ontology: BP
definition:
The modification of a host cell into an immortal cell line as a consequence of infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0020022
term: acidocalcisome
ontology: CC
definition:
An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.


go_id: GO:0020023
term: kinetoplast
ontology: CC
definition:
A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.


go_id: GO:0020025
term: subpellicular microtubule
ontology: CC
definition:
Singlet microtubules that lie underneath the inner membrane complex and emanate from the basal ring of the conoid.


go_id: GO:0020026
term: merozoite dense granule
ontology: CC
definition:
Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell.


go_id: GO:0020030
term: infected host cell surface knob
ontology: CC
definition:
Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species.


go_id: GO:0020031
term: polar ring of apical complex
ontology: CC
definition:
An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite.


go_id: GO:0020032
term: basal ring of apical complex
ontology: CC
definition:
An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite.


go_id: GO:0020033
term: antigenic variation
ontology: BP
definition:
Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system.


go_id: GO:0020035
term: cytoadherence to microvasculature, mediated by symbiont protein
ontology: BP
definition:
The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte.


go_id: GO:0020036
term: Maurer's cleft
ontology: CC
definition:
A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton.


go_id: GO:0020037
term: heme binding
ontology: MF
definition:
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.


go_id: GO:0020038
term: subpellicular network
ontology: CC
definition:
A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton.


go_id: GO:0020039
term: pellicle
ontology: CC
definition:
The structure enclosing an apicomplexan parasite cell; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles.


go_id: GO:0021501
term: prechordal plate formation
ontology: BP
definition:
The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.


go_id: GO:0021502
term: neural fold elevation formation
ontology: BP
definition:
The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.


go_id: GO:0021503
term: neural fold bending
ontology: BP
definition:
The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.


go_id: GO:0021504
term: neural fold hinge point formation
ontology: BP
definition:
The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.


go_id: GO:0021505
term: neural fold folding
ontology: BP
definition:
The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.


go_id: GO:0021506
term: anterior neuropore closure
ontology: BP
definition:
The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.


go_id: GO:0021507
term: posterior neuropore closure
ontology: BP
definition:
The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete.


go_id: GO:0021508
term: floor plate formation
ontology: BP
definition:
The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.


go_id: GO:0021509
term: roof plate formation
ontology: BP
definition:
The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.


go_id: GO:0021510
term: spinal cord development
ontology: BP
definition:
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.


go_id: GO:0021511
term: spinal cord patterning
ontology: BP
definition:
The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord.


go_id: GO:0021512
term: spinal cord anterior/posterior patterning
ontology: BP
definition:
The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord.


go_id: GO:0021513
term: spinal cord dorsal/ventral patterning
ontology: BP
definition:
The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.


go_id: GO:0021514
term: ventral spinal cord interneuron differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021515
term: cell differentiation in spinal cord
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021516
term: dorsal spinal cord development
ontology: BP
definition:
The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.


go_id: GO:0021517
term: ventral spinal cord development
ontology: BP
definition:
The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.


go_id: GO:0021518
term: spinal cord commissural neuron specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021519
term: spinal cord association neuron specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021520
term: spinal cord motor neuron cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021521
term: ventral spinal cord interneuron specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021522
term: spinal cord motor neuron differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021523
term: somatic motor neuron differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021524
term: visceral motor neuron differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021525
term: lateral motor column neuron differentiation
ontology: BP
definition:
The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021526
term: medial motor column neuron differentiation
ontology: BP
definition:
The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021527
term: spinal cord association neuron differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021528
term: commissural neuron differentiation in spinal cord
ontology: BP
definition:
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021529
term: spinal cord oligodendrocyte cell differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021530
term: spinal cord oligodendrocyte cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway.


go_id: GO:0021531
term: spinal cord radial glial cell differentiation
ontology: BP
definition:
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021532
term: neural tube patterning
ontology: BP
definition:
The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.


go_id: GO:0021533
term: cell differentiation in hindbrain
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.


go_id: GO:0021534
term: cell proliferation in hindbrain
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.


go_id: GO:0021536
term: diencephalon development
ontology: BP
definition:
The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.


go_id: GO:0021537
term: telencephalon development
ontology: BP
definition:
The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.


go_id: GO:0021538
term: epithalamus development
ontology: BP
definition:
The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.


go_id: GO:0021539
term: subthalamus development
ontology: BP
definition:
The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis.


go_id: GO:0021540
term: corpus callosum morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.


go_id: GO:0021541
term: ammon gyrus development
ontology: BP
definition:
The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons.


go_id: GO:0021542
term: dentate gyrus development
ontology: BP
definition:
The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.


go_id: GO:0021543
term: pallium development
ontology: BP
definition:
The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.


go_id: GO:0021544
term: subpallium development
ontology: BP
definition:
The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.


go_id: GO:0021545
term: cranial nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


go_id: GO:0021546
term: rhombomere development
ontology: BP
definition:
The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.


go_id: GO:0021547
term: midbrain-hindbrain boundary initiation
ontology: BP
definition:
The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


go_id: GO:0021548
term: pons development
ontology: BP
definition:
The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


go_id: GO:0021549
term: cerebellum development
ontology: BP
definition:
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


go_id: GO:0021550
term: medulla oblongata development
ontology: BP
definition:
The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


go_id: GO:0021551
term: central nervous system morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


go_id: GO:0021552
term: midbrain-hindbrain boundary structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


go_id: GO:0021553
term: olfactory nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


go_id: GO:0021554
term: optic nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.


go_id: GO:0021555
term: midbrain-hindbrain boundary morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


go_id: GO:0021556
term: central nervous system formation
ontology: BP
definition:
The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


go_id: GO:0021557
term: oculomotor nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


go_id: GO:0021558
term: trochlear nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


go_id: GO:0021559
term: trigeminal nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


go_id: GO:0021560
term: abducens nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


go_id: GO:0021561
term: facial nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


go_id: GO:0021562
term: vestibulocochlear nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


go_id: GO:0021563
term: glossopharyngeal nerve development
ontology: BP
definition:
Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


go_id: GO:0021564
term: vagus nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


go_id: GO:0021565
term: accessory nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


go_id: GO:0021566
term: hypoglossal nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


go_id: GO:0021567
term: rhombomere 1 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021568
term: rhombomere 2 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021569
term: rhombomere 3 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021570
term: rhombomere 4 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021571
term: rhombomere 5 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021572
term: rhombomere 6 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021573
term: rhombomere 7 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021574
term: rhombomere 8 development
ontology: BP
definition:
The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021575
term: hindbrain morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.


go_id: GO:0021576
term: hindbrain formation
ontology: BP
definition:
The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.


go_id: GO:0021577
term: hindbrain structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.


go_id: GO:0021578
term: hindbrain maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.


go_id: GO:0021579
term: medulla oblongata morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


go_id: GO:0021580
term: medulla oblongata formation
ontology: BP
definition:
The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


go_id: GO:0021581
term: medulla oblongata structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


go_id: GO:0021582
term: medulla oblongata maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.


go_id: GO:0021583
term: pons morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


go_id: GO:0021584
term: pons formation
ontology: BP
definition:
The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


go_id: GO:0021585
term: pons structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


go_id: GO:0021586
term: pons maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


go_id: GO:0021587
term: cerebellum morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


go_id: GO:0021588
term: cerebellum formation
ontology: BP
definition:
The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


go_id: GO:0021589
term: cerebellum structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


go_id: GO:0021590
term: cerebellum maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.


go_id: GO:0021591
term: ventricular system development
ontology: BP
definition:
The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.


go_id: GO:0021592
term: fourth ventricle development
ontology: BP
definition:
The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.


go_id: GO:0021593
term: rhombomere morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.


go_id: GO:0021594
term: rhombomere formation
ontology: BP
definition:
The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.


go_id: GO:0021595
term: rhombomere structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.


go_id: GO:0021597
term: central nervous system structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


go_id: GO:0021598
term: abducens nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


go_id: GO:0021599
term: abducens nerve formation
ontology: BP
definition:
The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


go_id: GO:0021600
term: abducens nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


go_id: GO:0021601
term: abducens nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


go_id: GO:0021602
term: cranial nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


go_id: GO:0021603
term: cranial nerve formation
ontology: BP
definition:
The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


go_id: GO:0021604
term: cranial nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


go_id: GO:0021605
term: cranial nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


go_id: GO:0021606
term: accessory nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


go_id: GO:0021607
term: accessory nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


go_id: GO:0021608
term: accessory nerve formation
ontology: BP
definition:
The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


go_id: GO:0021609
term: accessory nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


go_id: GO:0021610
term: facial nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


go_id: GO:0021611
term: facial nerve formation
ontology: BP
definition:
The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


go_id: GO:0021612
term: facial nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


go_id: GO:0021613
term: facial nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.


go_id: GO:0021614
term: glossopharyngeal nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


go_id: GO:0021615
term: glossopharyngeal nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


go_id: GO:0021616
term: glossopharyngeal nerve formation
ontology: BP
definition:
The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


go_id: GO:0021617
term: glossopharyngeal nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.


go_id: GO:0021618
term: hypoglossal nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


go_id: GO:0021619
term: hypoglossal nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


go_id: GO:0021620
term: hypoglossal nerve formation
ontology: BP
definition:
The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


go_id: GO:0021621
term: hypoglossal nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


go_id: GO:0021622
term: oculomotor nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


go_id: GO:0021623
term: oculomotor nerve formation
ontology: BP
definition:
The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


go_id: GO:0021624
term: oculomotor nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


go_id: GO:0021625
term: oculomotor nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.


go_id: GO:0021626
term: central nervous system maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


go_id: GO:0021627
term: olfactory nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


go_id: GO:0021628
term: olfactory nerve formation
ontology: BP
definition:
The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


go_id: GO:0021629
term: olfactory nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


go_id: GO:0021630
term: olfactory nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


go_id: GO:0021631
term: optic nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.


go_id: GO:0021632
term: optic nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.


go_id: GO:0021633
term: optic nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.


go_id: GO:0021634
term: optic nerve formation
ontology: BP
definition:
The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.


go_id: GO:0021635
term: trigeminal nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


go_id: GO:0021636
term: trigeminal nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


go_id: GO:0021637
term: trigeminal nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


go_id: GO:0021638
term: trigeminal nerve formation
ontology: BP
definition:
The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.


go_id: GO:0021639
term: trochlear nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


go_id: GO:0021640
term: trochlear nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


go_id: GO:0021641
term: trochlear nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


go_id: GO:0021642
term: trochlear nerve formation
ontology: BP
definition:
The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


go_id: GO:0021643
term: vagus nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


go_id: GO:0021644
term: vagus nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


go_id: GO:0021645
term: vagus nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


go_id: GO:0021646
term: vagus nerve formation
ontology: BP
definition:
The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.


go_id: GO:0021647
term: vestibulocochlear nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


go_id: GO:0021648
term: vestibulocochlear nerve morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


go_id: GO:0021649
term: vestibulocochlear nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


go_id: GO:0021650
term: vestibulocochlear nerve formation
ontology: BP
definition:
The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


go_id: GO:0021651
term: rhombomere 1 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021652
term: rhombomere 1 formation
ontology: BP
definition:
The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021653
term: rhombomere 1 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021654
term: rhombomere boundary formation
ontology: BP
definition:
The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021655
term: rhombomere 2 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021656
term: rhombomere 2 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021657
term: rhombomere 2 formation
ontology: BP
definition:
The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021658
term: rhombomere 3 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021659
term: rhombomere 3 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021660
term: rhombomere 3 formation
ontology: BP
definition:
The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021661
term: rhombomere 4 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021662
term: rhombomere 4 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021663
term: rhombomere 4 formation
ontology: BP
definition:
The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021664
term: rhombomere 5 morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021665
term: rhombomere 5 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021666
term: rhombomere 5 formation
ontology: BP
definition:
The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021667
term: rhombomere 6 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021668
term: rhombomere 6 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021669
term: rhombomere 6 formation
ontology: BP
definition:
The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021670
term: lateral ventricle development
ontology: BP
definition:
The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle.


go_id: GO:0021671
term: rhombomere 7 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021672
term: rhombomere 7 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021673
term: rhombomere 7 formation
ontology: BP
definition:
The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021674
term: rhombomere 8 morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021675
term: nerve development
ontology: BP
definition:
The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure.


go_id: GO:0021676
term: rhombomere 8 structural organization
ontology: BP
definition:
The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


go_id: GO:0021677
term: rhombomere 8 formation
ontology: BP
definition:
The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


go_id: GO:0021678
term: third ventricle development
ontology: BP
definition:
The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina.


go_id: GO:0021679
term: cerebellar molecular layer development
ontology: BP
definition:
The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


go_id: GO:0021680
term: cerebellar Purkinje cell layer development
ontology: BP
definition:
The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


go_id: GO:0021681
term: cerebellar granular layer development
ontology: BP
definition:
The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


go_id: GO:0021682
term: nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.


go_id: GO:0021683
term: cerebellar granular layer morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


go_id: GO:0021684
term: cerebellar granular layer formation
ontology: BP
definition:
The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


go_id: GO:0021685
term: cerebellar granular layer structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


go_id: GO:0021686
term: cerebellar granular layer maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


go_id: GO:0021687
term: cerebellar molecular layer morphogenesis
ontology: BP
definition:
The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


