# go_term

go_id: GO:0070924
term: heterochromatin assembly involved in chromatin silencing by small RNA
ontology: BP
definition:
The process in which an siRNA-associated RNA-induced silencing complex (siRISC) associates with nascent transcripts and RNA polymerase to induce the formation of heterochromatin.


go_id: GO:0070925
term: organelle assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.


go_id: GO:0070928
term: regulation of mRNA stability, ncRNA-mediated
ontology: BP
definition:
Any process, mediated by small non-coding RNAs, that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.


go_id: GO:0070929
term: trans-translation
ontology: BP
definition:
A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes.


go_id: GO:0070930
term: trans-translation-dependent protein tagging
ontology: BP
definition:
A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation.


go_id: GO:0070934
term: CRD-mediated mRNA stabilization
ontology: BP
definition:
An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).


go_id: GO:0070935
term: 3'-UTR-mediated mRNA stabilization
ontology: BP
definition:
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.


go_id: GO:0070936
term: protein K48-linked ubiquitination
ontology: BP
definition:
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.


go_id: GO:0070937
term: CRD-mediated mRNA stability complex
ontology: CC
definition:
A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, IGF2BP1 and at least four additional proteins: HNRNPU, SYNCRIP, YBX1, and DHX9.


go_id: GO:0070938
term: contractile ring
ontology: CC
definition:
A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles.


go_id: GO:0070939
term: Dsl1p complex
ontology: CC
definition:
A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.


go_id: GO:0070940
term: dephosphorylation of RNA polymerase II C-terminal domain
ontology: BP
definition:
The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.


go_id: GO:0070941
term: eisosome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face.


go_id: GO:0070948
term: regulation of neutrophil mediated cytotoxicity
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.


go_id: GO:0070949
term: regulation of neutrophil mediated killing of symbiont cell
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.


go_id: GO:0070950
term: regulation of neutrophil mediated killing of bacterium
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil.


go_id: GO:0070951
term: regulation of neutrophil mediated killing of gram-negative bacterium
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil.


go_id: GO:0070952
term: regulation of neutrophil mediated killing of gram-positive bacterium
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil.


go_id: GO:0070953
term: regulation of neutrophil mediated killing of fungus
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil.


go_id: GO:0070954
term: negative regulation of neutrophil mediated cytotoxicity
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.


go_id: GO:0070955
term: negative regulation of neutrophil mediated killing of symbiont cell
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.


go_id: GO:0070956
term: negative regulation of neutrophil mediated killing of bacterium
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.


go_id: GO:0070957
term: negative regulation of neutrophil mediated killing of gram-negative bacterium
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.


go_id: GO:0070958
term: negative regulation of neutrophil mediated killing of gram-positive bacterium
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.


go_id: GO:0070959
term: negative regulation of neutrophil mediated killing of fungus
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.


go_id: GO:0070960
term: positive regulation of neutrophil mediated cytotoxicity
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.


go_id: GO:0070961
term: positive regulation of neutrophil mediated killing of symbiont cell
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.


go_id: GO:0070962
term: positive regulation of neutrophil mediated killing of bacterium
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.


go_id: GO:0070963
term: positive regulation of neutrophil mediated killing of gram-negative bacterium
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.


go_id: GO:0070964
term: positive regulation of neutrophil mediated killing of gram-positive bacterium
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.


go_id: GO:0070965
term: positive regulation of neutrophil mediated killing of fungus
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.


go_id: GO:0070966
term: nuclear-transcribed mRNA catabolic process, no-go decay
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.


go_id: GO:0070967
term: coenzyme F420 binding
ontology: MF
definition:
Interacting selectively and non-covalently with F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.


go_id: GO:0070968
term: pyrroloquinoline quinone binding
ontology: MF
definition:
Interacting selectively and non-covalently with pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases.


go_id: GO:0070972
term: protein localization to endoplasmic reticulum
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.


go_id: GO:0070973
term: protein localization to endoplasmic reticulum exit site
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.


go_id: GO:0070974
term: POU domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors.


go_id: GO:0070975
term: FHA domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich.


go_id: GO:0070976
term: TIR domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.


go_id: GO:0070977
term: bone maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.


go_id: GO:0070978
term: voltage-gated calcium channel complex assembly
ontology: BP
definition:
Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.


go_id: GO:0070979
term: protein K11-linked ubiquitination
ontology: BP
definition:
A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.


go_id: GO:0070980
term: biphenyl catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).


go_id: GO:0070981
term: L-asparagine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.


go_id: GO:0070983
term: dendrite guidance
ontology: BP
definition:
The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.


go_id: GO:0070984
term: SET domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation.


go_id: GO:0070985
term: TFIIK complex
ontology: CC
definition:
A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin2p/CDK7.


go_id: GO:0070986
term: left/right axis specification
ontology: BP
definition:
The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).


go_id: GO:0070989
term: oxidative demethylation
ontology: BP
definition:
The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.


go_id: GO:0070990
term: snRNP binding
ontology: MF
definition:
Interacting selectively and non-covalently with any part of a small nuclear ribonucleoprotein particle.


go_id: GO:0070991
term: medium-chain-acyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a medium-chain fatty acid residue. A medium chain fatty acid is any fatty acid with a chain length of between C6 and C12.


go_id: GO:0070992
term: translation initiation complex
ontology: CC
definition:
A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.


go_id: GO:0070993
term: translation preinitiation complex
ontology: CC
definition:
A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA.


go_id: GO:0070994
term: detection of oxidative stress
ontology: BP
definition:
The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal.


go_id: GO:0070995
term: NADPH oxidation
ontology: BP
definition:
A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.


go_id: GO:0070998
term: sensory perception of gravity
ontology: BP
definition:
The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


go_id: GO:0070999
term: detection of mechanical stimulus involved in sensory perception of gravity
ontology: BP
definition:
The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal.


go_id: GO:0071000
term: response to magnetism
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.


go_id: GO:0071003
term: penta-snRNP complex
ontology: CC
definition:
A ribonucleoprotein complex formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins.


go_id: GO:0071004
term: U2-type prespliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.


go_id: GO:0071005
term: U2-type precatalytic spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.


go_id: GO:0071006
term: U2-type catalytic step 1 spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.


go_id: GO:0071007
term: U2-type catalytic step 2 spliceosome
ontology: CC
definition:
A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.


go_id: GO:0071008
term: U2-type post-mRNA release spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs.


go_id: GO:0071009
term: U4atac/U6atac x U5 tri-snRNP complex
ontology: CC
definition:
A ribonucleoprotein complex formed by the association of the U4atac/U6atac and U5 small nuclear ribonucleoproteins.


go_id: GO:0071010
term: prespliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.


go_id: GO:0071011
term: precatalytic spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.


go_id: GO:0071012
term: catalytic step 1 spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.


go_id: GO:0071013
term: catalytic step 2 spliceosome
ontology: CC
definition:
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.


go_id: GO:0071014
term: post-mRNA release spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5.


go_id: GO:0071015
term: U12-type prespliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.


go_id: GO:0071016
term: U12-type precatalytic spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.


go_id: GO:0071017
term: U12-type catalytic step 1 spliceosome
ontology: CC
definition:
A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.


go_id: GO:0071018
term: U12-type catalytic step 2 spliceosome
ontology: CC
definition:
A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.


go_id: GO:0071019
term: U12-type post-mRNA release spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.


go_id: GO:0071020
term: post-spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5.


go_id: GO:0071023
term: trans spliceosomal complex
ontology: CC
definition:
A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.


go_id: GO:0071026
term: cytoplasmic RNA surveillance
ontology: BP
definition:
The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm.


go_id: GO:0071027
term: nuclear RNA surveillance
ontology: BP
definition:
The set of processes involved in identifying and degrading defective or aberrant RNAs within the nucleus.


go_id: GO:0071028
term: nuclear mRNA surveillance
ontology: BP
definition:
The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nucleus.


go_id: GO:0071029
term: nuclear ncRNA surveillance
ontology: BP
definition:
The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus.


go_id: GO:0071030
term: nuclear mRNA surveillance of spliceosomal pre-mRNA splicing
ontology: BP
definition:
The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus.


go_id: GO:0071031
term: nuclear mRNA surveillance of mRNA 3'-end processing
ontology: BP
definition:
The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus.


go_id: GO:0071032
term: nuclear mRNA surveillance of mRNP export
ontology: BP
definition:
The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm.


go_id: GO:0071033
term: nuclear retention of pre-mRNA at the site of transcription
ontology: BP
definition:
The process involved in retention of aberrant or improperly formed mRNAs, e.g. those that are incorrectly or incompletely spliced or that have incorrectly formed 3'-ends, within the nucleus at the site of transcription.


go_id: GO:0071034
term: CUT catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs).


go_id: GO:0071035
term: nuclear polyadenylation-dependent rRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA.


go_id: GO:0071036
term: nuclear polyadenylation-dependent snoRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.


go_id: GO:0071037
term: nuclear polyadenylation-dependent snRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.


go_id: GO:0071038
term: nuclear polyadenylation-dependent tRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA.


go_id: GO:0071039
term: nuclear polyadenylation-dependent CUT catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.


go_id: GO:0071040
term: nuclear polyadenylation-dependent antisense transcript catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript.


go_id: GO:0071041
term: antisense RNA transcript catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.


go_id: GO:0071042
term: nuclear polyadenylation-dependent mRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.


go_id: GO:0071043
term: CUT metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome.


go_id: GO:0071045
term: nuclear histone mRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus.


go_id: GO:0071046
term: nuclear polyadenylation-dependent ncRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.


go_id: GO:0071047
term: polyadenylation-dependent mRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.


go_id: GO:0071048
term: nuclear retention of unspliced pre-mRNA at the site of transcription
ontology: BP
definition:
The process involved in retention of incorrectly or incompletely spliced pre-mRNA within the nucleus at the site of transcription.


go_id: GO:0071049
term: nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription
ontology: BP
definition:
The process involved in retention of mRNAs that have incorrectly formed 3'-ends within the nucleus at the site of transcription.


go_id: GO:0071050
term: snoRNA polyadenylation
ontology: BP
definition:
The enzymatic addition of a sequence of adenylyl residues at the 3' end of snoRNA molecule. In eukaryotes, this occurs in conjunction with termination of transcription of precursor snoRNA molecules and may occur post-transcriptionally on incorrectly processed molecules targeted for degradation.


go_id: GO:0071051
term: polyadenylation-dependent snoRNA 3'-end processing
ontology: BP
definition:
Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.


go_id: GO:0071052
term: alpha9-beta1 integrin-ADAM1 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1.


go_id: GO:0071053
term: alpha9-beta1 integrin-ADAM2 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2.


go_id: GO:0071054
term: alpha9-beta1 integrin-ADAM3 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3.


go_id: GO:0071055
term: alpha9-beta1 integrin-ADAM9 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9.


go_id: GO:0071056
term: alpha9-beta1 integrin-ADAM15 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15.


go_id: GO:0071057
term: alphav-beta3 integrin-ADAM15 complex
ontology: CC
definition:
A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15.


go_id: GO:0071063
term: sensory perception of wind
ontology: BP
definition:
The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal.


go_id: GO:0071065
term: alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1.


go_id: GO:0071066
term: detection of mechanical stimulus involved in sensory perception of wind
ontology: BP
definition:
The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal.


go_id: GO:0071067
term: alphav-beta3 integrin-ADAM23 complex
ontology: CC
definition:
A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23.


go_id: GO:0071068
term: alpha9-beta1 integrin-ADAM12 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.


go_id: GO:0071071
term: regulation of phospholipid biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


go_id: GO:0071072
term: negative regulation of phospholipid biosynthetic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


go_id: GO:0071073
term: positive regulation of phospholipid biosynthetic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


go_id: GO:0071074
term: eukaryotic initiation factor eIF2 binding
ontology: MF
definition:
Interacting selectively and non-covalently with eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation.


go_id: GO:0071075
term: CUGBP1-eIF2 complex
ontology: CC
definition:
A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation.


go_id: GO:0071078
term: fibronectin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion.


go_id: GO:0071079
term: alpha2-beta1 integrin-chondroadherin complex
ontology: CC
definition:
A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin.


go_id: GO:0071080
term: alpha3-beta1 integrin-basigin complex
ontology: CC
definition:
A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.


go_id: GO:0071082
term: alpha9-beta1 integrin-tenascin complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin.


go_id: GO:0071083
term: alphaV-beta3 integrin-CD47-FCER2 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2).


go_id: GO:0071084
term: alpha2-beta1 integrin-CD47 complex
ontology: CC
definition:
A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47.


go_id: GO:0071085
term: alphaIIb-beta3 integrin-CD9 complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9.


go_id: GO:0071086
term: alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib.


go_id: GO:0071088
term: alpha5-beta1 integrin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase.


go_id: GO:0071089
term: alphaV-beta3 integrin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase.


go_id: GO:0071090
term: alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase.


go_id: GO:0071091
term: alpha1-beta1 integrin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase.


go_id: GO:0071092
term: alpha3-beta1 integrin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase.


go_id: GO:0071093
term: alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase.


go_id: GO:0071094
term: alpha6-beta4 integrin-CD9 complex
ontology: CC
definition:
A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9.


go_id: GO:0071097
term: alphaV-beta3 integrin-paxillin-Pyk2 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2.


go_id: GO:0071098
term: alpha6-beta4 integrin-Fyn complex
ontology: CC
definition:
A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn.


go_id: GO:0071099
term: alphaV-beta6 integrin-TGFbeta-3 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3).


go_id: GO:0071100
term: alphaV-beta8 integrin-MMP14-TGFbeta-1 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).


go_id: GO:0071101
term: alpha4-beta1 integrin-JAM2 complex
ontology: CC
definition:
A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2.


go_id: GO:0071103
term: DNA conformation change
ontology: BP
definition:
A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.


go_id: GO:0071104
term: response to interleukin-9
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.


go_id: GO:0071105
term: response to interleukin-11
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.


go_id: GO:0071106
term: adenosine 3',5'-bisphosphate transmembrane transport
ontology: BP
definition:
The directed movement of adenosine 3',5'-bisphosphate across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0071107
term: response to parathyroid hormone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.


go_id: GO:0071108
term: protein K48-linked deubiquitination
ontology: BP
definition:
A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.


go_id: GO:0071109
term: superior temporal gyrus development
ontology: BP
definition:
The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus.


go_id: GO:0071111
term: cyclic-guanylate-specific phosphodiesterase activity
ontology: MF
definition:
Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+).


go_id: GO:0071112
term: alpha4-beta4 integrin-EMILIN-1 complex
ontology: CC
definition:
A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN).


go_id: GO:0071113
term: alphaIIb-beta3 integrin-ICAM-4 complex
ontology: CC
definition:
A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4.


go_id: GO:0071114
term: alphaV-beta3 integrin-tumstatin complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen.


go_id: GO:0071115
term: alpha5-beta1 integrin-endostatin complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen.


go_id: GO:0071116
term: alpha6-beta1 integrin-CYR61 complex
ontology: CC
definition:
A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis.


go_id: GO:0071117
term: alpha5-beta1 integrin-fibronectin-NOV complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV.


go_id: GO:0071118
term: alphaV-beta3 integrin-NOV complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV.


go_id: GO:0071119
term: alpha7-beta1 integrin-nicotinamide riboside kinase complex
ontology: CC
definition:
A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP).


go_id: GO:0071120
term: alpha4-beta1 integrin-CD47 complex
ontology: CC
definition:
A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47.


go_id: GO:0071121
term: alpha9-beta1 integrin-VEGF-D complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D.


go_id: GO:0071122
term: alpha9-beta1 integrin-VEGF-A complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A.


go_id: GO:0071123
term: alpha9-beta1 integrin-VEGF-C complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C.


go_id: GO:0071124
term: alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex
ontology: CC
definition:
A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2.


go_id: GO:0071125
term: alphaV-beta3 integrin-EGFR complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor.


go_id: GO:0071129
term: alphaV-beta3 integrin-LPP3 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3.


go_id: GO:0071130
term: alpha5-beta1 integrin-LPP3 complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3.


go_id: GO:0071132
term: alphaX-beta2 integrin-ICAM-4 complex
ontology: CC
definition:
A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4.


go_id: GO:0071133
term: alpha9-beta1 integrin-ADAM8 complex
ontology: CC
definition:
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.


go_id: GO:0071137
term: alphaV-beta3 integrin-CD98 complex
ontology: CC
definition:
A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98.


go_id: GO:0071138
term: alpha5-beta5-fibronectin-SFRP2 complex
ontology: CC
definition:
A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2.


go_id: GO:0071139
term: resolution of recombination intermediates
ontology: BP
definition:
The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.


go_id: GO:0071140
term: resolution of mitotic recombination intermediates
ontology: BP
definition:
The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged.


go_id: GO:0071147
term: TEAD-2 multiprotein complex
ontology: CC
definition:
A protein complex that consists of the DNA binding protein TEAD-2 bound to 12 other polypeptides including the transcriptional coactivator YAP, the multi-PDZ domain protein MPDZ (also called MUPP1), a 14-3-3 domain protein, and others.


go_id: GO:0071148
term: TEAD-1-YAP complex
ontology: CC
definition:
A transcription factor complex that is composed of the DNA binding protein TEAD-1 and the transcriptional coactivator YAP.


go_id: GO:0071149
term: TEAD-2-YAP complex
ontology: CC
definition:
A transcription factor complex that is composed of the DNA binding protein TEAD-2 and the transcriptional coactivator YAP.


go_id: GO:0071150
term: TEAD-3-YAP complex
ontology: CC
definition:
A transcription factor complex that is composed of the DNA binding protein TEAD-3 and the transcriptional coactivator YAP.


go_id: GO:0071151
term: TEAD-4-YAP complex
ontology: CC
definition:
A transcription factor complex that is composed of the DNA binding protein TEAD-4 and the transcriptional coactivator YAP.


go_id: GO:0071152
term: G-protein alpha(q)-synembrin complex
ontology: CC
definition:
A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein.


go_id: GO:0071153
term: G-protein alpha(o)-synembrin complex
ontology: CC
definition:
A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein.


go_id: GO:0071154
term: G-protein alpha(i)1-synembrin complex
ontology: CC
definition:
A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein.


go_id: GO:0071155
term: G-protein alpha(13)-synembrin complex
ontology: CC
definition:
A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein.


go_id: GO:0071156
term: regulation of cell cycle arrest
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.


go_id: GO:0071157
term: negative regulation of cell cycle arrest
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.


go_id: GO:0071158
term: positive regulation of cell cycle arrest
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.


go_id: GO:0071159
term: NF-kappaB complex
ontology: CC
definition:
A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression.


go_id: GO:0071160
term: cyanophycin synthetase activity (L-aspartate-adding)
ontology: MF
definition:
Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp.


go_id: GO:0071161
term: cyanophycin synthetase activity (L-arginine-adding)
ontology: MF
definition:
Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1.


go_id: GO:0071162
term: CMG complex
ontology: CC
definition:
A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.


go_id: GO:0071163
term: DNA replication preinitiation complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication, by the assembly of additional proteins onto an existing prereplicative complex.


go_id: GO:0071164
term: RNA trimethylguanosine synthase activity
ontology: MF
definition:
Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine.


go_id: GO:0071165
term: GINS complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks.


go_id: GO:0071166
term: ribonucleoprotein complex localization
ontology: BP
definition:
Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.


go_id: GO:0071168
term: protein localization to chromatin
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.


go_id: GO:0071171
term: site-specific DNA replication termination at RTS1 barrier
ontology: BP
definition:
A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching.


go_id: GO:0071173
term: spindle assembly checkpoint
ontology: BP
definition:
A cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.


go_id: GO:0071174
term: mitotic spindle checkpoint
ontology: BP
definition:
A mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.


go_id: GO:0071175
term: MAML2-RBP-Jkappa-ICN1 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071176
term: MAML2-RBP-Jkappa-ICN2 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071177
term: MAML2-RBP-Jkappa-ICN3 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071178
term: MAML2-RBP-Jkappa-ICN4 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071179
term: MAML3-RBP-Jkappa-ICN1 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071180
term: MAML3-RBP-Jkappa-ICN2 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071181
term: MAML3-RBP-Jkappa-ICN3 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071182
term: MAML3-RBP-Jkappa-ICN4 complex
ontology: CC
definition:
A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.


go_id: GO:0071183
term: protocadherin-alpha-protocadherin-gamma complex
ontology: CC
definition:
A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071184
term: protocadherin-alpha-v4-protocadherin-gamma-a1 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071185
term: protocadherin-alpha-v4-protocadherin-gamma-a3 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071186
term: protocadherin-alpha-v4-protocadherin-gamma-b2 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071187
term: protocadherin-alpha-v4-protocadherin-gamma-b4 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071188
term: protocadherin-alpha-v7-protocadherin-gamma-a1 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071189
term: protocadherin-alpha-v7-protocadherin-gamma-a3 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071190
term: protocadherin-alpha-v7-protocadherin-gamma-b2 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071191
term: protocadherin-alpha-v7-protocadherin-gamma-b4 complex
ontology: CC
definition:
A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.


go_id: GO:0071192
term: Kv4.2-KChIP1 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2.


go_id: GO:0071193
term: Kv4.2-KChIP2 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2.


go_id: GO:0071194
term: Kv4.2-KChIP3 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2.


go_id: GO:0071195
term: Kv4.2-KChIP4 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2.


go_id: GO:0071196
term: Kv4.3-KChIP1 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3.


go_id: GO:0071198
term: Kv4.1-DPP6 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1.


go_id: GO:0071199
term: Kv4.1-DPP10 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1.


go_id: GO:0071200
term: Kv4.2-DPP6 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2.


go_id: GO:0071201
term: Kv4.3-DPP6 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3.


go_id: GO:0071202
term: Kv4.3-DPP10 channel complex
ontology: CC
definition:
A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3.


go_id: GO:0071203
term: WASH complex
ontology: CC
definition:
A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.


go_id: GO:0071204
term: histone pre-mRNA 3'end processing complex
ontology: CC
definition:
A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1.


go_id: GO:0071205
term: protein localization to juxtaparanode region of axon
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon.


go_id: GO:0071207
term: histone pre-mRNA stem-loop binding
ontology: MF
definition:
Interacting selectively and non-covalently with a conserved stem-loop structure found in histone pre-mRNAs.


go_id: GO:0071208
term: histone pre-mRNA DCP binding
ontology: MF
definition:
Interacting selectively and non-covalently with the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing.


go_id: GO:0071210
term: protein insertion into membrane raft
ontology: BP
definition:
The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.


go_id: GO:0071211
term: protein targeting to vacuole involved in autophagy
ontology: BP
definition:
The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm.


go_id: GO:0071213
term: cellular response to 1-aminocyclopropane-1-carboxylic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.


go_id: GO:0071214
term: cellular response to abiotic stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.


go_id: GO:0071215
term: cellular response to abscisic acid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.


go_id: GO:0071216
term: cellular response to biotic stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.


go_id: GO:0071217
term: cellular response to external biotic stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.


go_id: GO:0071218
term: cellular response to misfolded protein
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.


go_id: GO:0071219
term: cellular response to molecule of bacterial origin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.


go_id: GO:0071220
term: cellular response to bacterial lipoprotein
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.


go_id: GO:0071221
term: cellular response to bacterial lipopeptide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.


go_id: GO:0071222
term: cellular response to lipopolysaccharide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.


go_id: GO:0071223
term: cellular response to lipoteichoic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


go_id: GO:0071224
term: cellular response to peptidoglycan
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.


go_id: GO:0071225
term: cellular response to muramyl dipeptide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.


go_id: GO:0071226
term: cellular response to molecule of fungal origin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.


go_id: GO:0071227
term: cellular response to molecule of oomycetes origin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.


go_id: GO:0071228
term: cellular response to tumor cell
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.


go_id: GO:0071229
term: cellular response to acid chemical
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.


go_id: GO:0071231
term: cellular response to folic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.


go_id: GO:0071232
term: cellular response to histidine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.


go_id: GO:0071233
term: cellular response to leucine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.


go_id: GO:0071234
term: cellular response to phenylalanine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.


go_id: GO:0071235
term: cellular response to proline
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.


go_id: GO:0071236
term: cellular response to antibiotic
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.


go_id: GO:0071237
term: cellular response to bacteriocin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.


go_id: GO:0071238
term: cellular response to brefeldin A
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.


go_id: GO:0071239
term: cellular response to streptomycin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


go_id: GO:0071240
term: cellular response to food
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.


go_id: GO:0071241
term: cellular response to inorganic substance
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.


go_id: GO:0071242
term: cellular response to ammonium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus.


go_id: GO:0071243
term: cellular response to arsenic-containing substance
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.


go_id: GO:0071244
term: cellular response to carbon dioxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.


go_id: GO:0071245
term: cellular response to carbon monoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.


go_id: GO:0071246
term: cellular response to chlorate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.


go_id: GO:0071247
term: cellular response to chromate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.


go_id: GO:0071248
term: cellular response to metal ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.


go_id: GO:0071249
term: cellular response to nitrate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.


go_id: GO:0071251
term: cellular response to silicon dioxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.


go_id: GO:0071252
term: cellular response to sulfur dioxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.


go_id: GO:0071253
term: connexin binding
ontology: MF
definition:
Interacting selectively and non-covalently with a connexin, any of a group of related proteins that assemble to form gap junctions.


go_id: GO:0071254
term: cytoplasmic U snRNP body
ontology: CC
definition:
A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies.


go_id: GO:0071255
term: CVT vesicle assembly
ontology: BP
definition:
A vesicle organization process that takes place as part of the CVT pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI).


go_id: GO:0071256
term: translocon complex
ontology: CC
definition:
A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.


go_id: GO:0071257
term: cellular response to electrical stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.


go_id: GO:0071258
term: cellular response to gravity
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.


go_id: GO:0071259
term: cellular response to magnetism
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.


go_id: GO:0071261
term: Ssh1 translocon complex
ontology: CC
definition:
A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences.


go_id: GO:0071262
term: regulation of translational initiation in response to starvation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.


go_id: GO:0071263
term: negative regulation of translational initiation in response to starvation
ontology: BP
definition:
Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment.


go_id: GO:0071264
term: positive regulation of translational initiation in response to starvation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.


go_id: GO:0071265
term: L-methionine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid.


go_id: GO:0071266
term: 'de novo' L-methionine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components.


go_id: GO:0071268
term: homocysteine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid.


go_id: GO:0071269
term: L-homocysteine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid.


go_id: GO:0071270
term: 1-butanol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O.


go_id: GO:0071271
term: 1-butanol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O.


go_id: GO:0071272
term: morphine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.


go_id: GO:0071273
term: morphine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.


go_id: GO:0071274
term: isoquinoline alkaloid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.


go_id: GO:0071275
term: cellular response to aluminum ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.


go_id: GO:0071276
term: cellular response to cadmium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.


go_id: GO:0071277
term: cellular response to calcium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.


go_id: GO:0071278
term: cellular response to cesium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.


go_id: GO:0071279
term: cellular response to cobalt ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.


go_id: GO:0071280
term: cellular response to copper ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.


go_id: GO:0071281
term: cellular response to iron ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.


go_id: GO:0071282
term: cellular response to iron(II) ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.


go_id: GO:0071283
term: cellular response to iron(III) ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.


go_id: GO:0071284
term: cellular response to lead ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.


go_id: GO:0071285
term: cellular response to lithium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.


go_id: GO:0071286
term: cellular response to magnesium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.


go_id: GO:0071287
term: cellular response to manganese ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.


go_id: GO:0071288
term: cellular response to mercury ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.


go_id: GO:0071289
term: cellular response to nickel ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus.


go_id: GO:0071290
term: cellular response to platinum ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.


go_id: GO:0071291
term: cellular response to selenium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.


go_id: GO:0071292
term: cellular response to silver ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.


go_id: GO:0071293
term: cellular response to tellurium ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.


go_id: GO:0071294
term: cellular response to zinc ion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.


go_id: GO:0071295
term: cellular response to vitamin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.


go_id: GO:0071296
term: cellular response to biotin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.


go_id: GO:0071297
term: cellular response to cobalamin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.


go_id: GO:0071298
term: cellular response to L-ascorbic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.


go_id: GO:0071299
term: cellular response to vitamin A
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.


go_id: GO:0071300
term: cellular response to retinoic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.


go_id: GO:0071301
term: cellular response to vitamin B1
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.


go_id: GO:0071302
term: cellular response to vitamin B2
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.


go_id: GO:0071303
term: cellular response to vitamin B3
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.


go_id: GO:0071304
term: cellular response to vitamin B6
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.


go_id: GO:0071305
term: cellular response to vitamin D
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.


go_id: GO:0071306
term: cellular response to vitamin E
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.


go_id: GO:0071307
term: cellular response to vitamin K
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.


go_id: GO:0071308
term: cellular response to menaquinone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.


go_id: GO:0071309
term: cellular response to phylloquinone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.


go_id: GO:0071310
term: cellular response to organic substance
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.


go_id: GO:0071311
term: cellular response to acetate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.


go_id: GO:0071312
term: cellular response to alkaloid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.


go_id: GO:0071313
term: cellular response to caffeine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.


go_id: GO:0071314
term: cellular response to cocaine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.


go_id: GO:0071315
term: cellular response to morphine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.


go_id: GO:0071316
term: cellular response to nicotine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.


go_id: GO:0071317
term: cellular response to isoquinoline alkaloid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.


go_id: GO:0071318
term: cellular response to ATP
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.


go_id: GO:0071319
term: cellular response to benzoic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.


go_id: GO:0071320
term: cellular response to cAMP
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.


go_id: GO:0071321
term: cellular response to cGMP
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.


go_id: GO:0071322
term: cellular response to carbohydrate stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.


go_id: GO:0071323
term: cellular response to chitin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.


go_id: GO:0071324
term: cellular response to disaccharide stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.


go_id: GO:0071325
term: cellular response to mannitol stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.


go_id: GO:0071326
term: cellular response to monosaccharide stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.


go_id: GO:0071327
term: cellular response to trehalose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.


go_id: GO:0071328
term: cellular response to maltose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.


go_id: GO:0071330
term: cellular response to trehalose-6-phosphate stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.


go_id: GO:0071331
term: cellular response to hexose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.


go_id: GO:0071332
term: cellular response to fructose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.


go_id: GO:0071333
term: cellular response to glucose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.


go_id: GO:0071334
term: cellular response to rhamnose stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.


go_id: GO:0071335
term: hair follicle cell proliferation
ontology: BP
definition:
The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population.


go_id: GO:0071339
term: MLL1 complex
ontology: CC
definition:
A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.


go_id: GO:0071340
term: skeletal muscle acetylcholine-gated channel clustering
ontology: BP
definition:
The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.


go_id: GO:0071341
term: medial cortical node
ontology: CC
definition:
A protein complex that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis.


go_id: GO:0071342
term: regulation of establishment of actomyosin contractile ring localization
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location that contributes to cytokinesis during cell cycle.


go_id: GO:0071345
term: cellular response to cytokine stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.


go_id: GO:0071346
term: cellular response to interferon-gamma
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.


go_id: GO:0071347
term: cellular response to interleukin-1
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.


go_id: GO:0071348
term: cellular response to interleukin-11
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.


go_id: GO:0071349
term: cellular response to interleukin-12
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.


go_id: GO:0071350
term: cellular response to interleukin-15
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.


go_id: GO:0071351
term: cellular response to interleukin-18
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.


go_id: GO:0071352
term: cellular response to interleukin-2
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.


go_id: GO:0071353
term: cellular response to interleukin-4
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.


go_id: GO:0071354
term: cellular response to interleukin-6
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.


go_id: GO:0071355
term: cellular response to interleukin-9
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.


go_id: GO:0071356
term: cellular response to tumor necrosis factor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.


go_id: GO:0071357
term: cellular response to type I interferon
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0071358
term: cellular response to type III interferon
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0071359
term: cellular response to dsRNA
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.


go_id: GO:0071360
term: cellular response to exogenous dsRNA
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.


go_id: GO:0071361
term: cellular response to ethanol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.


go_id: GO:0071362
term: cellular response to ether
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.


go_id: GO:0071363
term: cellular response to growth factor stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.


go_id: GO:0071364
term: cellular response to epidermal growth factor stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.


go_id: GO:0071365
term: cellular response to auxin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.


go_id: GO:0071366
term: cellular response to indolebutyric acid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.


go_id: GO:0071367
term: cellular response to brassinosteroid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.


go_id: GO:0071368
term: cellular response to cytokinin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.


go_id: GO:0071369
term: cellular response to ethylene stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.


go_id: GO:0071370
term: cellular response to gibberellin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.


go_id: GO:0071371
term: cellular response to gonadotropin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.


go_id: GO:0071372
term: cellular response to follicle-stimulating hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.


go_id: GO:0071373
term: cellular response to luteinizing hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.


go_id: GO:0071374
term: cellular response to parathyroid hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.


go_id: GO:0071375
term: cellular response to peptide hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.


go_id: GO:0071376
term: cellular response to corticotropin-releasing hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.


go_id: GO:0071377
term: cellular response to glucagon stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.


go_id: GO:0071378
term: cellular response to growth hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.


go_id: GO:0071379
term: cellular response to prostaglandin stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.


go_id: GO:0071380
term: cellular response to prostaglandin E stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.


go_id: GO:0071381
term: cellular response to prostaglandin F stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.


go_id: GO:0071382
term: cellular response to prostaglandin I stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.


go_id: GO:0071383
term: cellular response to steroid hormone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.


go_id: GO:0071384
term: cellular response to corticosteroid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.


go_id: GO:0071385
term: cellular response to glucocorticoid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


go_id: GO:0071386
term: cellular response to corticosterone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.


go_id: GO:0071387
term: cellular response to cortisol stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.


go_id: GO:0071388
term: cellular response to cortisone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.


go_id: GO:0071389
term: cellular response to mineralocorticoid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.


go_id: GO:0071390
term: cellular response to ecdysone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.


go_id: GO:0071391
term: cellular response to estrogen stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.


go_id: GO:0071392
term: cellular response to estradiol stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.


go_id: GO:0071393
term: cellular response to progesterone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.


go_id: GO:0071394
term: cellular response to testosterone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.


go_id: GO:0071395
term: cellular response to jasmonic acid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.


go_id: GO:0071396
term: cellular response to lipid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.


go_id: GO:0071397
term: cellular response to cholesterol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.


go_id: GO:0071398
term: cellular response to fatty acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.


go_id: GO:0071399
term: cellular response to linoleic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.


go_id: GO:0071400
term: cellular response to oleic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.


go_id: GO:0071401
term: cellular response to triglyceride
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.


go_id: GO:0071402
term: cellular response to lipoprotein particle stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.


go_id: GO:0071403
term: cellular response to high density lipoprotein particle stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.


go_id: GO:0071404
term: cellular response to low-density lipoprotein particle stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.


go_id: GO:0071405
term: cellular response to methanol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.


go_id: GO:0071406
term: cellular response to methylmercury
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.


go_id: GO:0071407
term: cellular response to organic cyclic compound
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.


go_id: GO:0071408
term: cellular response to cycloalkane
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.


go_id: GO:0071409
term: cellular response to cycloheximide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.


go_id: GO:0071410
term: cellular response to cyclopentenone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.


go_id: GO:0071411
term: cellular response to fluoxetine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.


go_id: GO:0071412
term: cellular response to genistein
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.


go_id: GO:0071413
term: cellular response to hydroxyisoflavone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.


go_id: GO:0071414
term: cellular response to methotrexate
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.


go_id: GO:0071415
term: cellular response to purine-containing compound
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.


go_id: GO:0071416
term: cellular response to tropane
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.


go_id: GO:0071417
term: cellular response to organonitrogen compound
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.


go_id: GO:0071418
term: cellular response to amine stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.


go_id: GO:0071419
term: cellular response to amphetamine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.


go_id: GO:0071420
term: cellular response to histamine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.


go_id: GO:0071421
term: manganese ion transmembrane transport
ontology: BP
definition:
A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0071422
term: succinate transmembrane transport
ontology: BP
definition:
A process in which a succinate ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0071423
term: malate transmembrane transport
ontology: BP
definition:
A process in which a malate ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0071424
term: rRNA (cytosine-N4-)-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N4-methylcytosine.


go_id: GO:0071425
term: hematopoietic stem cell proliferation
ontology: BP
definition:
The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.


go_id: GO:0071427
term: mRNA-containing ribonucleoprotein complex export from nucleus
ontology: BP
definition:
The directed movement of a ribonucleoprotein complex that contains messenger RNA from the nucleus to the cytoplasm.


go_id: GO:0071428
term: rRNA-containing ribonucleoprotein complex export from nucleus
ontology: BP
definition:
The directed movement of a ribonucleoprotein complex that contains ribosomal RNA from the nucleus to the cytoplasm.


go_id: GO:0071429
term: snRNA-containing ribonucleoprotein complex export from nucleus
ontology: BP
definition:
The directed movement of a ribonucleoprotein complex that contains small nuclear RNA from the nucleus to the cytoplasm.


go_id: GO:0071430
term: pre-miRNA-containing ribonucleoprotein complex export from nucleus
ontology: BP
definition:
The directed movement of a ribonucleoprotein complex that contains pre-microRNA from the nucleus to the cytoplasm.


go_id: GO:0071431
term: tRNA-containing ribonucleoprotein complex export from nucleus
ontology: BP
definition:
The directed movement of a ribonucleoprotein complex that contains transfer RNA from the nucleus to the cytoplasm.


go_id: GO:0071432
term: peptide mating pheromone maturation involved in conjugation with cellular fusion
ontology: BP
definition:
The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion.


go_id: GO:0071433
term: cell wall repair
ontology: BP
definition:
A process of cell wall organization that results in the restoration of the cell wall following damage.


go_id: GO:0071437
term: invadopodium
ontology: CC
definition:
A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate.


go_id: GO:0071439
term: clathrin complex
ontology: CC
definition:
A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.


go_id: GO:0071440
term: regulation of histone H3-K14 acetylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.


go_id: GO:0071441
term: negative regulation of histone H3-K14 acetylation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.


go_id: GO:0071442
term: positive regulation of histone H3-K14 acetylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.


go_id: GO:0071444
term: cellular response to pheromone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.


go_id: GO:0071446
term: cellular response to salicylic acid stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.


go_id: GO:0071447
term: cellular response to hydroperoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.


go_id: GO:0071448
term: cellular response to alkyl hydroperoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.


go_id: GO:0071449
term: cellular response to lipid hydroperoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.


go_id: GO:0071450
term: cellular response to oxygen radical
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.


go_id: GO:0071451
term: cellular response to superoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.


go_id: GO:0071452
term: cellular response to singlet oxygen
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.


go_id: GO:0071453
term: cellular response to oxygen levels
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.


go_id: GO:0071454
term: cellular response to anoxia
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.


go_id: GO:0071455
term: cellular response to hyperoxia
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.


go_id: GO:0071456
term: cellular response to hypoxia
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.


go_id: GO:0071457
term: cellular response to ozone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.


go_id: GO:0071458
term: integral component of cytoplasmic side of endoplasmic reticulum membrane
ontology: CC
definition:
The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.


go_id: GO:0071459
term: protein localization to chromosome, centromeric region
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome.


go_id: GO:0071460
term: cellular response to cell-matrix adhesion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion.


go_id: GO:0071461
term: cellular response to redox state
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.


go_id: GO:0071462
term: cellular response to water stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.


go_id: GO:0071463
term: cellular response to humidity
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.


go_id: GO:0071464
term: cellular response to hydrostatic pressure
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.


go_id: GO:0071465
term: cellular response to desiccation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.


go_id: GO:0071466
term: cellular response to xenobiotic stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.


go_id: GO:0071467
term: cellular response to pH
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.


go_id: GO:0071468
term: cellular response to acidic pH
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.


go_id: GO:0071469
term: cellular response to alkaline pH
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.


go_id: GO:0071470
term: cellular response to osmotic stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


go_id: GO:0071471
term: cellular response to non-ionic osmotic stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.


go_id: GO:0071472
term: cellular response to salt stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


go_id: GO:0071473
term: cellular response to cation stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.


go_id: GO:0071474
term: cellular hyperosmotic response
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.


go_id: GO:0071475
term: cellular hyperosmotic salinity response
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


go_id: GO:0071476
term: cellular hypotonic response
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.


go_id: GO:0071477
term: cellular hypotonic salinity response
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.


go_id: GO:0071478
term: cellular response to radiation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.


go_id: GO:0071479
term: cellular response to ionizing radiation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.


go_id: GO:0071480
term: cellular response to gamma radiation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.


go_id: GO:0071481
term: cellular response to X-ray
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).


go_id: GO:0071482
term: cellular response to light stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.


go_id: GO:0071483
term: cellular response to blue light
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.


go_id: GO:0071484
term: cellular response to light intensity
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.


go_id: GO:0071485
term: cellular response to absence of light
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.


go_id: GO:0071486
term: cellular response to high light intensity
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.


go_id: GO:0071487
term: cellular response to low light intensity stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.


go_id: GO:0071488
term: cellular response to very low light intensity stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.


go_id: GO:0071489
term: cellular response to red or far red light
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.


go_id: GO:0071490
term: cellular response to far red light
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.


go_id: GO:0071491
term: cellular response to red light
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.


go_id: GO:0071492
term: cellular response to UV-A
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.


go_id: GO:0071493
term: cellular response to UV-B
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.


go_id: GO:0071494
term: cellular response to UV-C
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.


go_id: GO:0071495
term: cellular response to endogenous stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.


go_id: GO:0071496
term: cellular response to external stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.


go_id: GO:0071497
term: cellular response to freezing
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.


go_id: GO:0071498
term: cellular response to fluid shear stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.


go_id: GO:0071499
term: cellular response to laminar fluid shear stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers.


go_id: GO:0071500
term: cellular response to nitrosative stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.


go_id: GO:0071501
term: cellular response to sterol depletion
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


go_id: GO:0071502
term: cellular response to temperature stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.


go_id: GO:0071503
term: response to heparin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.


go_id: GO:0071504
term: cellular response to heparin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.


go_id: GO:0071505
term: response to mycophenolic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.


go_id: GO:0071506
term: cellular response to mycophenolic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.


go_id: GO:0071508
term: activation of MAPK activity involved in conjugation with cellular fusion
ontology: BP
definition:
Any process that initiates the activity of the inactive enzyme MAP kinase in the context of conjugation with cellular fusion.


go_id: GO:0071509
term: activation of MAPKK activity involved in conjugation with cellular fusion
ontology: BP
definition:
Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of conjugation with cellular fusion.


go_id: GO:0071510
term: activation of MAPKKK activity involved in conjugation with cellular fusion
ontology: BP
definition:
Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of conjugation with cellular fusion.


go_id: GO:0071511
term: inactivation of MAPK activity involved in conjugation with cellular fusion
ontology: BP
definition:
Any process that terminates the activity of the active enzyme MAP kinase in the context of conjugation with cellular fusion.


go_id: GO:0071512
term: MAPK import into nucleus involved in conjugation with cellular fusion
ontology: BP
definition:
The directed movement of a MAP kinase to the nucleus that occurs in the context of conjugation with cellular fusion.


go_id: GO:0071513
term: phosphopantothenoylcysteine decarboxylase complex
ontology: CC
definition:
A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.


go_id: GO:0071514
term: genetic imprinting
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.


go_id: GO:0071515
term: genetic imprinting at mating-type locus
ontology: BP
definition:
A genetic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.


go_id: GO:0071516
term: establishment of imprinting at mating-type locus
ontology: BP
definition:
The initial formation of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.


go_id: GO:0071517
term: maintenance of imprinting at mating-type locus
ontology: BP
definition:
Any process involved in preserving the structure of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.


go_id: GO:0071518
term: autoinducer-2 kinase activity
ontology: MF
definition:
Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP.


go_id: GO:0071519
term: actomyosin contractile ring actin filament bundle assembly
ontology: BP
definition:
A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis.


go_id: GO:0071520
term: actomyosin contractile ring assembly actin filament bundle convergence
ontology: BP
definition:
A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring.


go_id: GO:0071521
term: Cdc42 GTPase complex
ontology: CC
definition:
A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signalling pathway.


go_id: GO:0071523
term: TIR domain-mediated complex assembly
ontology: BP
definition:
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TIR domain interaction.


go_id: GO:0071524
term: pyrrolysine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.


go_id: GO:0071525
term: pyrrolysine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.


go_id: GO:0071526
term: semaphorin-plexin signaling pathway
ontology: BP
definition:
A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.


go_id: GO:0071527
term: semaphorin-plexin signaling pathway involved in outflow tract morphogenesis
ontology: BP
definition:
A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis.


go_id: GO:0071528
term: tRNA re-export from nucleus
ontology: BP
definition:
The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export.


go_id: GO:0071529
term: cementum mineralization
ontology: BP
definition:
The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum.


go_id: GO:0071530
term: FHA domain-mediated complex assembly
ontology: BP
definition:
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an FHA (forkhead-associated) domain interaction.


go_id: GO:0071532
term: ankyrin repeat binding
ontology: MF
definition:
Interacting selectively and non-covalently with an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure.


go_id: GO:0071533
term: ankyrin repeat-mediated complex assembly
ontology: BP
definition:
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an ankyrin repeat interaction.


go_id: GO:0071534
term: zf-TRAF domain-mediated complex assembly
ontology: BP
definition:
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TRAF-type zinc finger (zf-TRAF) domain interaction.


go_id: GO:0071535
term: RING-like zinc finger domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain.


go_id: GO:0071536
term: RING-like zinc finger domain-mediated complex assembly
ontology: BP
definition:
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RING-like zinc finger domain interaction.


go_id: GO:0071537
term: C3HC4-type RING finger domain-mediated complex assembly
ontology: BP
definition:
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a C3HC4-type RING finger domain interaction.


go_id: GO:0071538
term: SH2 domain-mediated complex assembly
ontology: BP
definition:
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an SH2 domain interaction.


go_id: GO:0071542
term: dopaminergic neuron differentiation
ontology: BP
definition:
The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.


go_id: GO:0071543
term: diphosphoinositol polyphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.


go_id: GO:0071544
term: diphosphoinositol polyphosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.


go_id: GO:0071545
term: inositol phosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.


go_id: GO:0071546
term: pi-body
ontology: CC
definition:
A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.


go_id: GO:0071547
term: piP-body
ontology: CC
definition:
A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.


go_id: GO:0071548
term: response to dexamethasone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.


go_id: GO:0071549
term: cellular response to dexamethasone stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.


go_id: GO:0071550
term: death-inducing signaling complex assembly
ontology: BP
definition:
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway.


go_id: GO:0071551
term: RIP homotypic interaction motif binding
ontology: MF
definition:
Interacting selectively and non-covalently with a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases.


go_id: GO:0071552
term: RIP homotypic interaction motif-mediated complex assembly
ontology: BP
definition:
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RIP homotypic interaction motif (RHIM) interaction.


go_id: GO:0071553
term: G-protein coupled pyrimidinergic nucleotide receptor activity
ontology: MF
definition:
Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


go_id: GO:0071554
term: cell wall organization or biogenesis
ontology: BP
definition:
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.


go_id: GO:0071555
term: cell wall organization
ontology: BP
definition:
A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.


go_id: GO:0071556
term: integral component of lumenal side of endoplasmic reticulum membrane
ontology: CC
definition:
The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane.


go_id: GO:0071557
term: histone H3-K27 demethylation
ontology: BP
definition:
The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone.


go_id: GO:0071559
term: response to transforming growth factor beta
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.


go_id: GO:0071560
term: cellular response to transforming growth factor beta stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.


go_id: GO:0071561
term: nucleus-vacuole junction
ontology: CC
definition:
An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.


go_id: GO:0071562
term: nucleus-vacuole junction assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction, which are membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.


go_id: GO:0071563
term: Myo2p-Vac17p-Vac8p transport complex
ontology: CC
definition:
A protein complex that is involved in transport of vacuoles to a newly formed daughter cell. In yeast, this complex is composed of Myo2p, Vac17p, and Vac8p.


go_id: GO:0071564
term: npBAF complex
ontology: CC
definition:
A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.


go_id: GO:0071565
term: nBAF complex
ontology: CC
definition:
A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.


go_id: GO:0071566
term: UFM1 activating enzyme activity
ontology: MF
definition:
Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond.


go_id: GO:0071567
term: UFM1 hydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates.


go_id: GO:0071568
term: UFM1 transferase activity
ontology: MF
definition:
Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y --> Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages.


go_id: GO:0071570
term: cement gland development
ontology: BP
definition:
The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed.


go_id: GO:0071571
term: LRR domain-mediated complex assembly
ontology: BP
definition:
A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an LRR (leucine-rich repeat) domain interaction.


go_id: GO:0071572
term: histone H3-K56 deacetylation
ontology: BP
definition:
The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone.


go_id: GO:0071573
term: telosome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a telosome. A telosome is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase.


go_id: GO:0071575
term: integral component of external side of plasma membrane
ontology: CC
definition:
The component of the plasma membrane consisting of the gene products that penetrate only the external side of the membrane.


go_id: GO:0071576
term: tetrahydrodictyopterin binding
ontology: MF
definition:
Interacting selectively and non-covalently with tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one.


go_id: GO:0071577
term: zinc II ion transmembrane transport
ontology: BP
definition:
A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0071579
term: regulation of zinc ion transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0071580
term: regulation of zinc ion transmembrane transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.


go_id: GO:0071582
term: negative regulation of zinc ion transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0071583
term: negative regulation of zinc ion transmembrane transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.


go_id: GO:0071585
term: detoxification of cadmium ion
ontology: BP
definition:
Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.


go_id: GO:0071586
term: CAAX-box protein processing
ontology: BP
definition:
The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis.


go_id: GO:0071587
term: CAAX-box protein modification
ontology: BP
definition:
The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins.


go_id: GO:0071589
term: pyridine nucleoside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose.


go_id: GO:0071590
term: nicotinamide riboside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.


go_id: GO:0071591
term: nicotinic acid riboside metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.


go_id: GO:0071592
term: nicotinic acid riboside biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.


go_id: GO:0071594
term: thymocyte aggregation
ontology: BP
definition:
The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules.


go_id: GO:0071595
term: Nem1-Spo7 phosphatase complex
ontology: CC
definition:
A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p.


go_id: GO:0071596
term: ubiquitin-dependent protein catabolic process via the N-end rule pathway
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation.


go_id: GO:0071597
term: cellular birth scar
ontology: CC
definition:
Crater-like ring of chitinous scar tissue located on the surface of the daughter cell, in budding fungi, at the site of separation from the mother cell. It is formed after the newly emerged daughter cell separates, thereby marking the site of cytokinesis and septation.


go_id: GO:0071598
term: neuronal ribonucleoprotein granule
ontology: CC
definition:
A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli.


go_id: GO:0071599
term: otic vesicle development
ontology: BP
definition:
The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.


go_id: GO:0071600
term: otic vesicle morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.


go_id: GO:0071601
term: sphere organelle
ontology: CC
definition:
A nuclear body that is found in the germinal vesicles of amphibian oocytes, and consist of three major parts: a remarkably spherical body about 5-10 pm in diameter, smaller spherical or nearly spherical granules on the surface, and inclusions of various sizes that strongly resemble the surface granules. The parts of the sphere organelle have distinct compositions, including splicing snRNAs and proteins.


go_id: GO:0071602
term: phytosphingosine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol.


go_id: GO:0071604
term: transforming growth factor beta production
ontology: BP
definition:
The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.


go_id: GO:0071605
term: monocyte chemotactic protein-1 production
ontology: BP
definition:
The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071606
term: chemokine (C-C motif) ligand 4 production
ontology: BP
definition:
The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071607
term: macrophage inflammatory protein-1 gamma production
ontology: BP
definition:
The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071608
term: macrophage inflammatory protein-1 alpha production
ontology: BP
definition:
The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071609
term: chemokine (C-C motif) ligand 5 production
ontology: BP
definition:
The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071610
term: chemokine (C-C motif) ligand 1 production
ontology: BP
definition:
The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071611
term: granulocyte colony-stimulating factor production
ontology: BP
definition:
The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071612
term: IP-10 production
ontology: BP
definition:
The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071613
term: granzyme B production
ontology: BP
definition:
The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071614
term: linoleic acid epoxygenase activity
ontology: MF
definition:
Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.


go_id: GO:0071615
term: oxidative deethylation
ontology: BP
definition:
The process of removing one or more ethyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.


go_id: GO:0071616
term: acyl-CoA biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.


go_id: GO:0071619
term: phosphorylation of RNA polymerase II C-terminal domain serine 2 residues
ontology: BP
definition:
The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans.


go_id: GO:0071620
term: phosphorylation of RNA polymerase II C-terminal domain serine 5 residues
ontology: BP
definition:
The process of introducing a phosphate group onto a serine residue at position 5 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 5 (Ser5) occurs near the 5' ends of genes. It is generally still observed in the middle of genes, overlapping with phosphorylation of serine 2, but is generally not present at the 3' ends of genes. In vivo, Ser5 phosphorylation occurs primarily through the action of TFIIH (KIN28 in S. cerevisiae, CKD7 in metazoans).


go_id: GO:0071622
term: regulation of granulocyte chemotaxis
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.


go_id: GO:0071623
term: negative regulation of granulocyte chemotaxis
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.


go_id: GO:0071624
term: positive regulation of granulocyte chemotaxis
ontology: BP
definition:
Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.


go_id: GO:0071627
term: integral component of fungal-type vacuolar membrane
ontology: CC
definition:
The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.


go_id: GO:0071628
term: intrinsic component of fungal-type vacuolar membrane
ontology: CC
definition:
The component of a fungal-type vacuole membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.


go_id: GO:0071629
term: cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.


go_id: GO:0071630
term: nucleus-associated proteasomal ubiquitin-dependent protein catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation.


go_id: GO:0071631
term: mating pheromone secretion involved in conjugation with cellular fusion
ontology: BP
definition:
The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.


go_id: GO:0071632
term: optomotor response
ontology: BP
definition:
Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish.


go_id: GO:0071634
term: regulation of transforming growth factor beta production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta.


go_id: GO:0071635
term: negative regulation of transforming growth factor beta production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.


go_id: GO:0071636
term: positive regulation of transforming growth factor beta production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.


go_id: GO:0071637
term: regulation of monocyte chemotactic protein-1 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1.


go_id: GO:0071638
term: negative regulation of monocyte chemotactic protein-1 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1.


go_id: GO:0071639
term: positive regulation of monocyte chemotactic protein-1 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1.


go_id: GO:0071640
term: regulation of macrophage inflammatory protein 1 alpha production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.


go_id: GO:0071641
term: negative regulation of macrophage inflammatory protein 1 alpha production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.


go_id: GO:0071642
term: positive regulation of macrophage inflammatory protein 1 alpha production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.


go_id: GO:0071643
term: regulation of chemokine (C-C motif) ligand 4 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.


go_id: GO:0071644
term: negative regulation of chemokine (C-C motif) ligand 4 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.


go_id: GO:0071645
term: positive regulation of chemokine (C-C motif) ligand 4 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.


go_id: GO:0071646
term: regulation of macrophage inflammatory protein-1 gamma production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.


go_id: GO:0071647
term: negative regulation of macrophage inflammatory protein-1 gamma production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.


go_id: GO:0071648
term: positive regulation of macrophage inflammatory protein-1 gamma production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.


go_id: GO:0071649
term: regulation of chemokine (C-C motif) ligand 5 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.


go_id: GO:0071650
term: negative regulation of chemokine (C-C motif) ligand 5 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.


go_id: GO:0071651
term: positive regulation of chemokine (C-C motif) ligand 5 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.


go_id: GO:0071652
term: regulation of chemokine (C-C motif) ligand 1 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.


go_id: GO:0071653
term: negative regulation of chemokine (C-C motif) ligand 1 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.


go_id: GO:0071654
term: positive regulation of chemokine (C-C motif) ligand 1 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.


go_id: GO:0071655
term: regulation of granulocyte colony-stimulating factor production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor.


go_id: GO:0071656
term: negative regulation of granulocyte colony-stimulating factor production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor.


go_id: GO:0071657
term: positive regulation of granulocyte colony-stimulating factor production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.


go_id: GO:0071662
term: negative regulation of granzyme B production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B.


go_id: GO:0071664
term: catenin-TCF7L2 complex
ontology: CC
definition:
A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.


go_id: GO:0071665
term: gamma-catenin-TCF7L2 complex
ontology: CC
definition:
A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.


go_id: GO:0071666
term: Slit-Robo signaling complex
ontology: CC
definition:
A protein-carbohydrate complex that consists of a transmembrane roundabout (Robo) receptor, an extracellular Slit ligand and heparin/heparan sulfate.


go_id: GO:0071668
term: plant-type cell wall assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall.


go_id: GO:0071669
term: plant-type cell wall organization or biogenesis
ontology: BP
definition:
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.


go_id: GO:0071672
term: negative regulation of smooth muscle cell chemotaxis
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.


go_id: GO:0071673
term: positive regulation of smooth muscle cell chemotaxis
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.


go_id: GO:0071675
term: regulation of mononuclear cell migration
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.


go_id: GO:0071676
term: negative regulation of mononuclear cell migration
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.


go_id: GO:0071677
term: positive regulation of mononuclear cell migration
ontology: BP
definition:
Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.


go_id: GO:0071678
term: olfactory bulb axon guidance
ontology: BP
definition:
The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues.


go_id: GO:0071679
term: commissural neuron axon guidance
ontology: BP
definition:
The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.


go_id: GO:0071680
term: response to indole-3-methanol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.


go_id: GO:0071681
term: cellular response to indole-3-methanol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.


go_id: GO:0071683
term: sensory dendrite
ontology: CC
definition:
A dendrite that is found on a sensory neuron, and directly transduces a sensory signal from the sensory neuron to another neuron.


go_id: GO:0071684
term: organism emergence from protective structure
ontology: BP
definition:
The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case.


go_id: GO:0071685
term: NADH dehydrogenase complex (plastoquinone)
ontology: CC
definition:
An NADH dehydrogenase complex that catalyzes the transfer of electrons to plastoquinone. The complex is involved in the non-photochemical reduction of plastoquinones and the cyclic electron transport around photosystem I, and is found in plastid thylakoids.


go_id: GO:0071686
term: horsetail nucleus
ontology: CC
definition:
The elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe.


go_id: GO:0071687
term: horsetail nucleus leading edge
ontology: CC
definition:
The part of the horsetail nucleus where telomeres cluster under the SPB and that leads horsetail movement. The horsetail nucleus is the elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe.


go_id: GO:0071688
term: striated muscle myosin thick filament assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle.


go_id: GO:0071689
term: muscle thin filament assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.


go_id: GO:0071690
term: cardiac muscle myosin thick filament assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle.


go_id: GO:0071691
term: cardiac muscle thin filament assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle.


go_id: GO:0071692
term: protein localization to extracellular region
ontology: BP
definition:
Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.


go_id: GO:0071693
term: protein transport within extracellular region
ontology: BP
definition:
The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore.


go_id: GO:0071694
term: maintenance of protein location in extracellular region
ontology: BP
definition:
Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere.


go_id: GO:0071695
term: anatomical structure maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.


go_id: GO:0071696
term: ectodermal placode development
ontology: BP
definition:
The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.


go_id: GO:0071697
term: ectodermal placode morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.


go_id: GO:0071698
term: olfactory placode development
ontology: BP
definition:
The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.


go_id: GO:0071699
term: olfactory placode morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.


go_id: GO:0071700
term: olfactory placode maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.


go_id: GO:0071701
term: regulation of MAPK export from nucleus
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm.


go_id: GO:0071702
term: organic substance transport
ontology: BP
definition:
The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.


go_id: GO:0071703
term: detection of organic substance
ontology: BP
definition:
The series of events in which an organic substance stimulus is received by a cell and converted into a molecular signal.


go_id: GO:0071704
term: organic substance metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.


go_id: GO:0071705
term: nitrogen compound transport
ontology: BP
definition:
The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0071706
term: tumor necrosis factor superfamily cytokine production
ontology: BP
definition:
The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071707
term: immunoglobulin heavy chain V-D-J recombination
ontology: BP
definition:
The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).


go_id: GO:0071708
term: immunoglobulin light chain V-J recombination
ontology: BP
definition:
The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).


go_id: GO:0071710
term: membrane macromolecule biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell.


go_id: GO:0071711
term: basement membrane organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.


go_id: GO:0071712
term: ER-associated misfolded protein catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation.


go_id: GO:0071715
term: icosanoid transport
ontology: BP
definition:
The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.


go_id: GO:0071716
term: leukotriene transport
ontology: BP
definition:
The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.


go_id: GO:0071717
term: thromboxane transport
ontology: BP
definition:
The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.


go_id: GO:0071718
term: sodium-independent icosanoid transport
ontology: BP
definition:
The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.


go_id: GO:0071719
term: sodium-independent leukotriene transport
ontology: BP
definition:
The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.


go_id: GO:0071720
term: sodium-independent prostaglandin transport
ontology: BP
definition:
The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0071721
term: sodium-independent thromboxane transport
ontology: BP
definition:
The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.


go_id: GO:0071722
term: detoxification of arsenic-containing substance
ontology: BP
definition:
Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds.


go_id: GO:0071724
term: response to diacyl bacterial lipopeptide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.


go_id: GO:0071725
term: response to triacyl bacterial lipopeptide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.


go_id: GO:0071726
term: cellular response to diacyl bacterial lipopeptide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.


go_id: GO:0071727
term: cellular response to triacyl bacterial lipopeptide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.


go_id: GO:0071728
term: beak development
ontology: BP
definition:
The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.


go_id: GO:0071729
term: beak morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.


go_id: GO:0071730
term: beak formation
ontology: BP
definition:
The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.


go_id: GO:0071731
term: response to nitric oxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.


go_id: GO:0071732
term: cellular response to nitric oxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.


go_id: GO:0071733
term: transcriptional activation by promoter-enhancer looping
ontology: BP
definition:
The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.


go_id: GO:0071734
term: biotin-[pyruvate-carboxylase] ligase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + biotin + apo-(pyruvate-carboxylase) = AMP + diphosphate + biotin-(pyruvate-carboxylase).


go_id: GO:0071735
term: IgG immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071736
term: IgG immunoglobulin complex, circulating
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071737
term: IgG B cell receptor complex
ontology: CC
definition:
An IgG immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


go_id: GO:0071738
term: IgD immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071739
term: IgD immunoglobulin complex, circulating
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071740
term: IgD B cell receptor complex
ontology: CC
definition:
An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


go_id: GO:0071741
term: IgD immunoglobulin complex, GPI-anchored
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells.


go_id: GO:0071742
term: IgE immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071743
term: IgE immunoglobulin complex, circulating
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071744
term: IgE B cell receptor complex
ontology: CC
definition:
An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


go_id: GO:0071745
term: IgA immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071746
term: IgA immunoglobulin complex, circulating
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071747
term: IgA B cell receptor complex
ontology: CC
definition:
An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


go_id: GO:0071748
term: monomeric IgA immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071749
term: polymeric IgA immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071750
term: dimeric IgA immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071751
term: secretory IgA immunoglobulin complex
ontology: CC
definition:
A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component.


go_id: GO:0071753
term: IgM immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071754
term: IgM immunoglobulin complex, circulating
ontology: CC
definition:
A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph.


go_id: GO:0071755
term: IgM B cell receptor complex
ontology: CC
definition:
An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


go_id: GO:0071756
term: pentameric IgM immunoglobulin complex
ontology: CC
definition:
A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide.


go_id: GO:0071757
term: hexameric IgM immunoglobulin complex
ontology: CC
definition:
A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide.


go_id: GO:0071758
term: IgW immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071759
term: IgX immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071760
term: IgY immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


go_id: GO:0071761
term: IgZ immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgZ isotype and two identical immunoglobulin light chains, held together by disulfide bonds. The IgZ isotype is also known as the IgT isotype in certain species of fish.


go_id: GO:0071762
term: heavy chain immunoglobulin complex
ontology: CC
definition:
A protein complex composed of two identical immunoglobulin heavy chains of the IgNAR isotype held together by disulfide bonds and lacking immunoglobulin light chains.


go_id: GO:0071763
term: nuclear membrane organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.


go_id: GO:0071764
term: nuclear outer membrane organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane.


go_id: GO:0071765
term: nuclear inner membrane organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane.


go_id: GO:0071766
term: Actinobacterium-type cell wall biogenesis
ontology: BP
definition:
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.


go_id: GO:0071767
term: mycolic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.


go_id: GO:0071768
term: mycolic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.


go_id: GO:0071769
term: mycolate cell wall layer assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer.


go_id: GO:0071770
term: DIM/DIP cell wall layer assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall.


go_id: GO:0071772
term: response to BMP
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.


go_id: GO:0071773
term: cellular response to BMP stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.


go_id: GO:0071774
term: response to fibroblast growth factor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus.


go_id: GO:0071781
term: endoplasmic reticulum cisternal network
ontology: CC
definition:
A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae.  These are typically found close to the nucleus and are generally more prominent in secretory cells.


go_id: GO:0071782
term: endoplasmic reticulum tubular network
ontology: CC
definition:
A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.


go_id: GO:0071783
term: endoplasmic reticulum cisternal network organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.


go_id: GO:0071784
term: endoplasmic reticulum cisternal network assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.


go_id: GO:0071785
term: endoplasmic reticulum cisternal network maintenance
ontology: BP
definition:
The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.


go_id: GO:0071786
term: endoplasmic reticulum tubular network organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section.


go_id: GO:0071787
term: endoplasmic reticulum tubular network assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.


go_id: GO:0071788
term: endoplasmic reticulum tubular network maintenance
ontology: BP
definition:
The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.


go_id: GO:0071789
term: spindle pole body localization to nuclear envelope
ontology: BP
definition:
A process in which a spindle pole body is transported to, or maintained in, a specific location in the nuclear envelope. A spindle pole body is a type of microtubule organizing center found in fungal cells.


go_id: GO:0071790
term: establishment of spindle pole body localization to nuclear envelope
ontology: BP
definition:
A process in which a spindle pole body is transported to a specific location in the nuclear envelope. A spindle pole body is a type of microtubule organizing center found in fungal cells.


go_id: GO:0071792
term: bacillithiol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.


go_id: GO:0071793
term: bacillithiol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.


go_id: GO:0071794
term: CAP-Gly domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets.


go_id: GO:0071795
term: K11-linked polyubiquitin binding
ontology: MF
definition:
Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers.


go_id: GO:0071796
term: K6-linked polyubiquitin binding
ontology: MF
definition:
Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers.


go_id: GO:0071797
term: LUBAC complex
ontology: CC
definition:
A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex.


go_id: GO:0071798
term: response to prostaglandin D
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.


go_id: GO:0071799
term: cellular response to prostaglandin D stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.


go_id: GO:0071800
term: podosome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.


go_id: GO:0071806
term: protein transmembrane transport
ontology: BP
definition:
The directed movement of a protein across a membrane by means of some agent such as a transporter or pore.


go_id: GO:0071808
term: satellite fibril
ontology: CC
definition:
An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section).


go_id: GO:0071809
term: regulation of fever generation by regulation of prostaglandin biosynthesis
ontology: BP
definition:
Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.


go_id: GO:0071810
term: regulation of fever generation by regulation of prostaglandin secretion
ontology: BP
definition:
Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.


go_id: GO:0071811
term: positive regulation of fever generation by positive regulation of prostaglandin biosynthesis
ontology: BP
definition:
Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.


go_id: GO:0071812
term: positive regulation of fever generation by positive regulation of prostaglandin secretion
ontology: BP
definition:
Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.


go_id: GO:0071814
term: protein-lipid complex binding
ontology: MF
definition:
Interacting selectively and non-covalently with a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules.


go_id: GO:0071815
term: intermediate-density lipoprotein particle binding
ontology: MF
definition:
Interacting selectively and non-covalently with a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm.


go_id: GO:0071816
term: tail-anchored membrane protein insertion into ER membrane
ontology: BP
definition:
A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.


go_id: GO:0071817
term: MMXD complex
ontology: CC
definition:
A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation.


go_id: GO:0071818
term: BAT3 complex
ontology: CC
definition:
A protein complex consisting of BAT3 (BAG6) and its cofactors. In mammals these cofactors are TRC35 (GET4) and UBL4A. It facilitates tail-anchored protein capture by ASNA1/TRC4 and also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD).


go_id: GO:0071819
term: DUBm complex
ontology: CC
definition:
A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p.


go_id: GO:0071820
term: N-box binding
ontology: MF
definition:
Interacting selectively and non-covalently with an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses.


go_id: GO:0071821
term: FANCM-MHF complex
ontology: CC
definition:
A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes.


go_id: GO:0071822
term: protein complex subunit organization
ontology: BP
definition:
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.


go_id: GO:0071823
term: protein-carbohydrate complex subunit organization
ontology: BP
definition:
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex.


go_id: GO:0071824
term: protein-DNA complex subunit organization
ontology: BP
definition:
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex.


go_id: GO:0071825
term: protein-lipid complex subunit organization
ontology: BP
definition:
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex.


go_id: GO:0071826
term: ribonucleoprotein complex subunit organization
ontology: BP
definition:
Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex.


go_id: GO:0071827
term: plasma lipoprotein particle organization
ontology: BP
definition:
A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins.


go_id: GO:0071828
term: apolipoprotein E recycling
ontology: BP
definition:
The process in which chylomicron remnant-associated apolipoprotein E is internalized by endocytosis, localized to recycling endosomes and then secreted in association with a high-density lipoprotein particle.


go_id: GO:0071830
term: triglyceride-rich lipoprotein particle clearance
ontology: BP
definition:
The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


go_id: GO:0071831
term: intermediate-density lipoprotein particle clearance
ontology: BP
definition:
The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


go_id: GO:0071832
term: peptide pheromone export involved in conjugation
ontology: BP
definition:
The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.


go_id: GO:0071833
term: peptide pheromone export involved in conjugation with cellular fusion
ontology: BP
definition:
The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.


go_id: GO:0071834
term: mating pheromone secretion
ontology: BP
definition:
The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction.


go_id: GO:0071835
term: mating pheromone secretion involved in conjugation
ontology: BP
definition:
The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.


go_id: GO:0071836
term: nectar secretion
ontology: BP
definition:
The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins.


go_id: GO:0071837
term: HMG box domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin.


go_id: GO:0071838
term: cell proliferation in bone marrow
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow.


go_id: GO:0071840
term: cellular component organization or biogenesis
ontology: BP
definition:
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.


go_id: GO:0071846
term: actin filament debranching
ontology: BP
definition:
An actin filament severing process that results in the removal of actin filament branches specifically at the branch points.


go_id: GO:0071847
term: TNFSF11-mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of tumor necrosis factor ligand superfamily member 11 (TNFSF11) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0071848
term: positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
ontology: BP
definition:
Any TNFSF11-mediated signaling process that increases the rate, frequency, or extent of the ERK1 and ERK2 cascade.


go_id: GO:0071849
term: G1 cell cycle arrest in response to nitrogen starvation
ontology: BP
definition:
The process in which the cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.


go_id: GO:0071850
term: mitotic cell cycle arrest
ontology: BP
definition:
The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M).


go_id: GO:0071851
term: mitotic G1 cell cycle arrest in response to nitrogen starvation
ontology: BP
definition:
The process in which the mitotic cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.


go_id: GO:0071852
term: fungal-type cell wall organization or biogenesis
ontology: BP
definition:
A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall.


go_id: GO:0071854
term: cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly
ontology: BP
definition:
The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall.


go_id: GO:0071864
term: positive regulation of cell proliferation in bone marrow
ontology: BP
definition:
A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.


go_id: GO:0071865
term: regulation of apoptotic process in bone marrow
ontology: BP
definition:
Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow.


go_id: GO:0071866
term: negative regulation of apoptotic process in bone marrow
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.


go_id: GO:0071867
term: response to monoamine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.


go_id: GO:0071868
term: cellular response to monoamine stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.


go_id: GO:0071869
term: response to catecholamine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.


go_id: GO:0071870
term: cellular response to catecholamine stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.


go_id: GO:0071871
term: response to epinephrine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.


go_id: GO:0071872
term: cellular response to epinephrine stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.


go_id: GO:0071873
term: response to norepinephrine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.


go_id: GO:0071874
term: cellular response to norepinephrine stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.


go_id: GO:0071875
term: adrenergic receptor signaling pathway
ontology: BP
definition:
A series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.


go_id: GO:0071877
term: regulation of adrenergic receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of an adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.


go_id: GO:0071878
term: negative regulation of adrenergic receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.


go_id: GO:0071879
term: positive regulation of adrenergic receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.


go_id: GO:0071880
term: adenylate cyclase-activating adrenergic receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).


go_id: GO:0071881
term: adenylate cyclase-inhibiting adrenergic receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).


go_id: GO:0071882
term: phospholipase C-activating adrenergic receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).


go_id: GO:0071883
term: activation of MAPK activity by adrenergic receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, followed by the activation of a MAP kinase.


go_id: GO:0071884
term: vitamin D receptor activator activity
ontology: MF
definition:
Interacting (directly or indirectly) with vitamin D receptors such that the proportion of receptors in the active form is increased.


go_id: GO:0071885
term: N-terminal protein N-methyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.


go_id: GO:0071886
term: 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
ontology: MF
definition:
Interacting selectively and non-covalently with the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug.


go_id: GO:0071887
term: leukocyte apoptotic process
ontology: BP
definition:
Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.


go_id: GO:0071889
term: 14-3-3 protein binding
ontology: MF
definition:
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.


go_id: GO:0071892
term: thrombocyte activation
ontology: BP
definition:
A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals.


go_id: GO:0071893
term: BMP signaling pathway involved in nephric duct formation
ontology: BP
definition:
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to nephric duct formation.


go_id: GO:0071894
term: histone H2B conserved C-terminal lysine ubiquitination
ontology: BP
definition:
A histone ubiquitination process in which a ubiquitin monomer is added to a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.


go_id: GO:0071895
term: odontoblast differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.


go_id: GO:0071897
term: DNA biosynthetic process
ontology: BP
definition:
The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.


go_id: GO:0071898
term: regulation of estrogen receptor binding
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of estrogen receptor binding, interacting selectively with a an estrogen receptor.


go_id: GO:0071899
term: negative regulation of estrogen receptor binding
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of estrogen receptor binding, interacting selectively with an estrogen receptor.


go_id: GO:0071900
term: regulation of protein serine/threonine kinase activity
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity.


go_id: GO:0071901
term: negative regulation of protein serine/threonine kinase activity
ontology: BP
definition:
Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity.


go_id: GO:0071902
term: positive regulation of protein serine/threonine kinase activity
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.


go_id: GO:0071903
term: protein N-linked N-acetylglucosaminylation via asparagine
ontology: BP
definition:
A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue.


go_id: GO:0071904
term: protein N-linked N-acetylgalactosaminylation via asparagine
ontology: BP
definition:
A process of protein N-linked glycosylation via asparagine in which N-acetylgalactosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid residue.


go_id: GO:0071905
term: protein N-linked glucosylation via asparagine
ontology: BP
definition:
A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue.


go_id: GO:0071906
term: CRD domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a CRD (context dependent regulatory) domain, a domain of about 130 residues that is the most divergent region among the LEF/TCF proteins.


go_id: GO:0071907
term: determination of digestive tract left/right asymmetry
ontology: BP
definition:
Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed.


go_id: GO:0071908
term: determination of intestine left/right asymmetry
ontology: BP
definition:
Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.


go_id: GO:0071909
term: determination of stomach left/right asymmetry
ontology: BP
definition:
Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism.


go_id: GO:0071910
term: determination of liver left/right asymmetry
ontology: BP
definition:
Determination of the asymmetric location of the liver with respect to the left and right halves of the organism.


go_id: GO:0071911
term: synchronous neurotransmitter secretion
ontology: BP
definition:
Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion.


go_id: GO:0071912
term: asynchronous neurotransmitter secretion
ontology: BP
definition:
Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion.


go_id: GO:0071913
term: citrate secondary active transmembrane transporter activity
ontology: MF
definition:
Catalysis of the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.


go_id: GO:0071914
term: prominosome
ontology: CC
definition:
An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known.


go_id: GO:0071915
term: protein-lysine lysylation
ontology: BP
definition:
The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).


go_id: GO:0071916
term: dipeptide transmembrane transporter activity
ontology: MF
definition:
Enables the directed movement of a dipeptide across a membrane into, out of or within a cell, or between cells. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.


go_id: GO:0071918
term: urea transmembrane transport
ontology: BP
definition:
The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0071919
term: G-quadruplex DNA formation
ontology: BP
definition:
A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature.


go_id: GO:0071920
term: cleavage body
ontology: CC
definition:
A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.


go_id: GO:0071921
term: cohesin localization to chromatin
ontology: BP
definition:
A process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.


go_id: GO:0071922
term: regulation of cohesin localization to chromatin
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.


go_id: GO:0071923
term: negative regulation of cohesin localization to chromatin
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.


go_id: GO:0071924
term: chemokine (C-C motif) ligand 22 production
ontology: BP
definition:
The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071925
term: thymic stromal lymphopoietin production
ontology: BP
definition:
The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071926
term: endocannabinoid signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of an endocannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Endocannabinoids are small molecules derived from arachidonic acid, anandamide (arachidonoylethanolamide) and 2-arachidonoylglycerol.


go_id: GO:0071927
term: octopamine signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of octopamine binding to a cell surface receptor.


go_id: GO:0071928
term: tyramine signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor.


go_id: GO:0071931
term: positive regulation of transcription involved in G1/S transition of mitotic cell cycle
ontology: BP
definition:
Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.


go_id: GO:0071932
term: replication fork reversal
ontology: BP
definition:
Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved.


go_id: GO:0071933
term: Arp2/3 complex binding
ontology: MF
definition:
Interacting selectively and non-covalently with an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5).


go_id: GO:0071934
term: thiamine transmembrane transport
ontology: BP
definition:
The directed movement of thiamine across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.


go_id: GO:0071935
term: octopamine signaling pathway involved in response to food
ontology: BP
definition:
The series of molecular signals initiated by binding of octopamine to a receptor on the surface of the target cell that contributes to a response to a food stimulus.


go_id: GO:0071936
term: coreceptor activity involved in Wnt signaling pathway
ontology: MF
definition:
In cooperation with a primary Wnt receptor, initiating a change in cell activity through the Wnt signaling pathway.


go_id: GO:0071938
term: vitamin A transport
ontology: BP
definition:
The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.


go_id: GO:0071939
term: vitamin A import
ontology: BP
definition:
The directed movement of vitamin A into a cell or organelle. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.


go_id: GO:0071940
term: fungal-type cell wall assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall.


go_id: GO:0071941
term: nitrogen cycle metabolic process
ontology: BP
definition:
A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.


go_id: GO:0071942
term: XPC complex
ontology: CC
definition:
A nucleotide-excision repair complex that is involved in damage sensing during global genome nucleotide excision repair (GG-NER). It is part of the pre-incision (or initial recognition) complex bound to sites of DNA damage. In human, it is composed of XPC, RAD23B and CETN2.


go_id: GO:0071944
term: cell periphery
ontology: CC
definition:
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.


go_id: GO:0071945
term: regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed
ontology: BP
definition:
A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein.


go_id: GO:0071946
term: cis-acting DNA replication termination
ontology: BP
definition:
A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing.


go_id: GO:0071947
term: protein deubiquitination involved in ubiquitin-dependent protein catabolic process
ontology: BP
definition:
The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism.


go_id: GO:0071948
term: activation-induced B cell apoptotic process
ontology: BP
definition:
B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death.


go_id: GO:0071949
term: FAD binding
ontology: MF
definition:
Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.


go_id: GO:0071950
term: FADH2 binding
ontology: MF
definition:
Interacting selectively and non-covalently with the reduced form, FADH2, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.


go_id: GO:0071951
term: conversion of methionyl-tRNA to N-formyl-methionyl-tRNA
ontology: BP
definition:
The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet).


go_id: GO:0071952
term: conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA
ontology: BP
definition:
The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA.


go_id: GO:0071953
term: elastic fiber
ontology: CC
definition:
An extracellular matrix part that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain.


go_id: GO:0071954
term: chemokine (C-C motif) ligand 11 production
ontology: BP
definition:
The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0071957
term: old mitotic spindle pole body
ontology: CC
definition:
The spindle pole body that exists in a cell prior to spindle pole body duplication. An old spindle pole body segregates to the daughter cell upon mitosis, and lacks active proteins involved in signaling exit from mitosis.


go_id: GO:0071958
term: new mitotic spindle pole body
ontology: CC
definition:
The spindle pole body that is formed by spindle pole body duplication, and to which proteins involved in mitotic exit signaling (for example, the septation initiation network in fission yeast) localize.


go_id: GO:0071959
term: maintenance of mitotic sister chromatid cohesion, arms
ontology: BP
definition:
The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.


go_id: GO:0071960
term: maintenance of mitotic sister chromatid cohesion, centromeric
ontology: BP
definition:
The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.


go_id: GO:0071961
term: mitotic sister chromatid cohesion, arms
ontology: BP
definition:
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis.


go_id: GO:0071963
term: establishment or maintenance of cell polarity regulating cell shape
ontology: BP
definition:
Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.


go_id: GO:0071964
term: establishment of cell polarity regulating cell shape
ontology: BP
definition:
Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell.


go_id: GO:0071965
term: multicellular organismal locomotion
ontology: BP
definition:
Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another.


go_id: GO:0071966
term: fungal-type cell wall polysaccharide metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall.


go_id: GO:0071967
term: lipopolysaccharide core heptosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+.


go_id: GO:0071968
term: lipid A-core heptosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+.


go_id: GO:0071971
term: extracellular exosome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.


go_id: GO:0071977
term: bacterial-type flagellum-dependent swimming motility
ontology: BP
definition:
Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium.


go_id: GO:0071978
term: bacterial-type flagellum-dependent swarming motility
ontology: BP
definition:
Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria.


go_id: GO:0071979
term: cytoskeleton-mediated cell swimming
ontology: BP
definition:
Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium.


go_id: GO:0071980
term: cell surface adhesin-mediated gliding motility
ontology: BP
definition:
Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins.


go_id: GO:0071981
term: exit from diapause
ontology: BP
definition:
The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.


go_id: GO:0071982
term: maintenance of diapause
ontology: BP
definition:
The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.


go_id: GO:0071983
term: exit from reproductive diapause
ontology: BP
definition:
The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.


go_id: GO:0071984
term: maintenance of reproductive diapause
ontology: BP
definition:
The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.


go_id: GO:0071985
term: multivesicular body sorting pathway
ontology: BP
definition:
A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded.


go_id: GO:0071986
term: Ragulator complex
ontology: CC
definition:
A protein complex that contains MAPKSP1 (MP1, Map2k1ip1), ROBLD3 (p14, Mapbpip), C11orf59 (p18), LAMTOR4 and LAMTOR5. The complex is anchored to lipid rafts in late endosome membranes via C11orf59, recruits mTORC1 to lysosomal membranes in amino acid signaling to mTORC1, constitutes a guanine nucleotide exchange factor (GEF) for the Rag GTPases, and is also involved in ERK/MAPK signaling.


go_id: GO:0071987
term: WD40-repeat domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain.


go_id: GO:0071990
term: maintenance of protein location in spindle pole body
ontology: BP
definition:
Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere.


go_id: GO:0071991
term: phytochelatin transporter activity
ontology: MF
definition:
Enables the directed movement of a phytochelatin into, out of or within a cell, or between cells. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.


go_id: GO:0071992
term: phytochelatin transmembrane transporter activity
ontology: MF
definition:
Enables the directed movement of a phytochelatin across a membrane into, out of or within a cell, or between cells. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.


go_id: GO:0071993
term: phytochelatin transport
ontology: BP
definition:
The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.


go_id: GO:0071994
term: phytochelatin transmembrane transport
ontology: BP
definition:
The directed movement of a phytochelatin across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.


go_id: GO:0071995
term: phytochelatin import into vacuole
ontology: BP
definition:
The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.


go_id: GO:0071997
term: glutathione S-conjugate-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of glutathione S-conjugate across a membrane.


go_id: GO:0071998
term: ascospore release from ascus
ontology: BP
definition:
A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive.


go_id: GO:0071999
term: extracellular polysaccharide catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of polysaccharides used in extracellular structures.


go_id: GO:0072000
term: extracellular polysaccharide catabolic process involved in ascospore release from ascus
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus.


go_id: GO:0072001
term: renal system development
ontology: BP
definition:
The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels.


go_id: GO:0072002
term: Malpighian tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.


go_id: GO:0072003
term: kidney rudiment formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


go_id: GO:0072004
term: kidney field specification
ontology: BP
definition:
The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop.


go_id: GO:0072005
term: maintenance of kidney identity
ontology: BP
definition:
The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


go_id: GO:0072006
term: nephron development
ontology: BP
definition:
The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.


go_id: GO:0072007
term: mesangial cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state.


go_id: GO:0072008
term: glomerular mesangial cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state.


go_id: GO:0072009
term: nephron epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron.


go_id: GO:0072010
term: glomerular epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.


go_id: GO:0072011
term: glomerular endothelium development
ontology: BP
definition:
The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus.


go_id: GO:0072012
term: glomerulus vasculature development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.


go_id: GO:0072013
term: glomus development
ontology: BP
definition:
The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment.


go_id: GO:0072014
term: proximal tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.


go_id: GO:0072015
term: glomerular visceral epithelial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells.


go_id: GO:0072016
term: glomerular parietal epithelial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


go_id: GO:0072017
term: distal tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.


go_id: GO:0072019
term: proximal convoluted tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule.


go_id: GO:0072020
term: proximal straight tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule.


go_id: GO:0072021
term: ascending thin limb development
ontology: BP
definition:
The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.


go_id: GO:0072022
term: descending thin limb development
ontology: BP
definition:
The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle.


go_id: GO:0072023
term: thick ascending limb development
ontology: BP
definition:
The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.


go_id: GO:0072024
term: macula densa development
ontology: BP
definition:
The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus.


go_id: GO:0072025
term: distal convoluted tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.


go_id: GO:0072027
term: connecting tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct.


go_id: GO:0072028
term: nephron morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.


go_id: GO:0072029
term: long nephron development
ontology: BP
definition:
The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla.


go_id: GO:0072030
term: short nephron development
ontology: BP
definition:
The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.


go_id: GO:0072031
term: proximal convoluted tubule segment 1 development
ontology: BP
definition:
The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.


go_id: GO:0072032
term: proximal convoluted tubule segment 2 development
ontology: BP
definition:
The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.


go_id: GO:0072033
term: renal vesicle formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.


go_id: GO:0072034
term: renal vesicle induction
ontology: BP
definition:
Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle.


go_id: GO:0072035
term: pre-tubular aggregate formation
ontology: BP
definition:
The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.


go_id: GO:0072036
term: mesenchymal to epithelial transition involved in renal vesicle formation
ontology: BP
definition:
A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle.


go_id: GO:0072037
term: mesenchymal stem cell differentiation involved in nephron morphogenesis
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


go_id: GO:0072038
term: mesenchymal stem cell maintenance involved in nephron morphogenesis
ontology: BP
definition:
The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


go_id: GO:0072039
term: regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
ontology: BP
definition:
Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.


go_id: GO:0072040
term: negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
ontology: BP
definition:
Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.


go_id: GO:0072041
term: positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
ontology: BP
definition:
Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.


go_id: GO:0072042
term: regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron.


go_id: GO:0072043
term: regulation of pre-tubular aggregate formation by cell-cell signaling
ontology: BP
definition:
Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.


go_id: GO:0072044
term: collecting duct development
ontology: BP
definition:
The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder.


go_id: GO:0072045
term: convergent extension involved in nephron morphogenesis
ontology: BP
definition:
The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron.


go_id: GO:0072046
term: establishment of planar polarity involved in nephron morphogenesis
ontology: BP
definition:
Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron.


go_id: GO:0072047
term: proximal/distal pattern formation involved in nephron development
ontology: BP
definition:
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).


go_id: GO:0072048
term: renal system pattern specification
ontology: BP
definition:
Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system.


go_id: GO:0072049
term: comma-shaped body morphogenesis
ontology: BP
definition:
The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.


go_id: GO:0072050
term: S-shaped body morphogenesis
ontology: BP
definition:
The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.


go_id: GO:0072051
term: juxtaglomerular apparatus development
ontology: BP
definition:
The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function.


go_id: GO:0072052
term: juxtaglomerulus cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.


go_id: GO:0072053
term: renal inner medulla development
ontology: BP
definition:
The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.


go_id: GO:0072054
term: renal outer medulla development
ontology: BP
definition:
The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla.


go_id: GO:0072055
term: renal cortex development
ontology: BP
definition:
The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.


go_id: GO:0072056
term: pyramid development
ontology: BP
definition:
The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts.


go_id: GO:0072057
term: inner stripe development
ontology: BP
definition:
The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.


go_id: GO:0072058
term: outer stripe development
ontology: BP
definition:
The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.


go_id: GO:0072059
term: cortical collecting duct development
ontology: BP
definition:
The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex.


go_id: GO:0072060
term: outer medullary collecting duct development
ontology: BP
definition:
The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.


go_id: GO:0072061
term: inner medullary collecting duct development
ontology: BP
definition:
The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla.


go_id: GO:0072062
term: proximal convoluted tubule segment 1 cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state.


go_id: GO:0072063
term: short descending thin limb development
ontology: BP
definition:
The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology.


go_id: GO:0072064
term: long descending thin limb development
ontology: BP
definition:
The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.


go_id: GO:0072065
term: long descending thin limb bend development
ontology: BP
definition:
The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment.


go_id: GO:0072066
term: prebend segment development
ontology: BP
definition:
The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.


go_id: GO:0072067
term: early distal convoluted tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive.


go_id: GO:0072068
term: late distal convoluted tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.


go_id: GO:0072069
term: DCT cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state.


go_id: GO:0072070
term: loop of Henle development
ontology: BP
definition:
The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.


go_id: GO:0072071
term: kidney interstitial fibroblast differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state.


go_id: GO:0072072
term: kidney stroma development
ontology: BP
definition:
The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney.


go_id: GO:0072073
term: kidney epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.


go_id: GO:0072074
term: kidney mesenchyme development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.


go_id: GO:0072075
term: metanephric mesenchyme development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.


go_id: GO:0072076
term: nephrogenic mesenchyme development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.


go_id: GO:0072077
term: renal vesicle morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.


go_id: GO:0072078
term: nephron tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.


go_id: GO:0072079
term: nephron tubule formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.


go_id: GO:0072080
term: nephron tubule development
ontology: BP
definition:
The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.


go_id: GO:0072081
term: specification of nephron tubule identity
ontology: BP
definition:
The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity.


go_id: GO:0072087
term: renal vesicle development
ontology: BP
definition:
The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.


go_id: GO:0072088
term: nephron epithelium morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron.


go_id: GO:0072089
term: stem cell proliferation
ontology: BP
definition:
The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.


go_id: GO:0072090
term: mesenchymal stem cell proliferation involved in nephron morphogenesis
ontology: BP
definition:
The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron.


go_id: GO:0072091
term: regulation of stem cell proliferation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.


go_id: GO:0072092
term: ureteric bud invasion
ontology: BP
definition:
The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros.


go_id: GO:0072094
term: metanephric renal vesicle induction
ontology: BP
definition:
Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle.


go_id: GO:0072095
term: regulation of branch elongation involved in ureteric bud branching
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.


go_id: GO:0072096
term: negative regulation of branch elongation involved in ureteric bud branching
ontology: BP
definition:
Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.


go_id: GO:0072097
ontology: BP
term:
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway

definition:
A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor resulting in the reduction of the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.


go_id: GO:0072098
term: anterior/posterior pattern specification involved in kidney development
ontology: BP
definition:
The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.


go_id: GO:0072099
term: anterior/posterior pattern specification involved in ureteric bud development
ontology: BP
definition:
The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.


go_id: GO:0072100
term: specification of ureteric bud anterior/posterior symmetry
ontology: BP
definition:
The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.


go_id: GO:0072101
term: specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
ontology: BP
definition:
A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.


go_id: GO:0072102
term: glomerulus morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.


go_id: GO:0072103
term: glomerulus vasculature morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.


go_id: GO:0072104
term: glomerular capillary formation
ontology: BP
definition:
The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.


go_id: GO:0072105
term: ureteric peristalsis
ontology: BP
definition:
A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.


go_id: GO:0072106
term: regulation of ureteric bud formation
ontology: BP
definition:
Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.


go_id: GO:0072107
term: positive regulation of ureteric bud formation
ontology: BP
definition:
Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.


go_id: GO:0072108
term: positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
ontology: BP
definition:
Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.


go_id: GO:0072109
term: glomerular mesangium development
ontology: BP
definition:
The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.


go_id: GO:0072110
term: glomerular mesangial cell proliferation
ontology: BP
definition:
The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population.


go_id: GO:0072111
term: cell proliferation involved in kidney development
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.


go_id: GO:0072112
term: glomerular visceral epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells.


go_id: GO:0072113
term: head kidney development
ontology: BP
definition:
The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis.


go_id: GO:0072114
term: pronephros morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


go_id: GO:0072115
term: head kidney morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.


go_id: GO:0072116
term: pronephros formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


go_id: GO:0072117
term: head kidney formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.


go_id: GO:0072118
term: pronephros structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


go_id: GO:0072119
term: head kidney structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.


go_id: GO:0072120
term: pronephros maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


go_id: GO:0072121
term: head kidney maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.


go_id: GO:0072122
term: extraglomerular mesangial cell proliferation
ontology: BP
definition:
The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.


go_id: GO:0072123
term: intraglomerular mesangial cell proliferation
ontology: BP
definition:
The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.


go_id: GO:0072124
term: regulation of glomerular mesangial cell proliferation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation.


go_id: GO:0072125
term: negative regulation of glomerular mesangial cell proliferation
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation.


go_id: GO:0072126
term: positive regulation of glomerular mesangial cell proliferation
ontology: BP
definition:
Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.


go_id: GO:0072127
term: renal capsule development
ontology: BP
definition:
The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.


go_id: GO:0072128
term: renal capsule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.


go_id: GO:0072129
term: renal capsule formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.


go_id: GO:0072130
term: renal capsule specification
ontology: BP
definition:
The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


go_id: GO:0072131
term: kidney mesenchyme morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.


go_id: GO:0072132
term: mesenchyme morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells.


go_id: GO:0072133
term: metanephric mesenchyme morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.


go_id: GO:0072134
term: nephrogenic mesenchyme morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.


go_id: GO:0072135
term: kidney mesenchymal cell proliferation
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney.


go_id: GO:0072136
term: metanephric mesenchymal cell proliferation involved in metanephros development
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population.


go_id: GO:0072137
term: condensed mesenchymal cell proliferation
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.


go_id: GO:0072138
term: mesenchymal cell proliferation involved in ureteric bud development
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development.


go_id: GO:0072139
term: glomerular parietal epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


go_id: GO:0072140
term: DCT cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure.


go_id: GO:0072141
term: renal interstitial fibroblast development
ontology: BP
definition:
The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure.


go_id: GO:0072142
term: juxtaglomerulus cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure.


go_id: GO:0072143
term: mesangial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure.


go_id: GO:0072144
term: glomerular mesangial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure.


go_id: GO:0072145
term: proximal convoluted tubule segment 1 cell development
ontology: BP
definition:
The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure.


go_id: GO:0072146
term: DCT cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell.


go_id: GO:0072147
term: glomerular parietal epithelial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.


go_id: GO:0072148
term: epithelial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell.


go_id: GO:0072149
term: glomerular visceral epithelial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells.


go_id: GO:0072150
term: juxtaglomerulus cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell.


go_id: GO:0072151
term: mesangial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell.


go_id: GO:0072152
term: glomerular mesangial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell.


go_id: GO:0072153
term: renal interstitial fibroblast fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast.


go_id: GO:0072154
term: proximal convoluted tubule segment 1 cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney.


go_id: GO:0072155
term: epithelial cell migration involved in nephron tubule morphogenesis
ontology: BP
definition:
The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis.


go_id: GO:0072156
term: distal tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.


go_id: GO:0072157
term: epithelial cell migration involved in distal tubule morphogenesis
ontology: BP
definition:
The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis.


go_id: GO:0072158
term: proximal tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.


go_id: GO:0072159
term: epithelial cell migration involved in proximal tubule morphogenesis
ontology: BP
definition:
The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis.


go_id: GO:0072160
term: nephron tubule epithelial cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.


go_id: GO:0072161
term: mesenchymal cell differentiation involved in kidney development
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state.


go_id: GO:0072162
term: metanephric mesenchymal cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.


go_id: GO:0072163
term: mesonephric epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.


go_id: GO:0072164
term: mesonephric tubule development
ontology: BP
definition:
The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros.


go_id: GO:0072165
term: anterior mesonephric tubule development
ontology: BP
definition:
The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros.


go_id: GO:0072166
term: posterior mesonephric tubule development
ontology: BP
definition:
The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros.


go_id: GO:0072170
term: metanephric tubule development
ontology: BP
definition:
The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros.


go_id: GO:0072171
term: mesonephric tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.


go_id: GO:0072172
term: mesonephric tubule formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros.


go_id: GO:0072173
term: metanephric tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.


go_id: GO:0072176
term: nephric duct development
ontology: BP
definition:
The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.


go_id: GO:0072177
term: mesonephric duct development
ontology: BP
definition:
The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros.


go_id: GO:0072178
term: nephric duct morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney.


go_id: GO:0072179
term: nephric duct formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney.


go_id: GO:0072180
term: mesonephric duct morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.


go_id: GO:0072181
term: mesonephric duct formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube drains the mesonephros.


go_id: GO:0072182
term: regulation of nephron tubule epithelial cell differentiation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation.


go_id: GO:0072183
term: negative regulation of nephron tubule epithelial cell differentiation
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation.


go_id: GO:0072184
term: renal vesicle progenitor cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing.


go_id: GO:0072185
term: metanephric cap development
ontology: BP
definition:
The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.


go_id: GO:0072186
term: metanephric cap morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.


go_id: GO:0072187
term: metanephric cap formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.


go_id: GO:0072189
term: ureter development
ontology: BP
definition:
The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.


go_id: GO:0072190
term: ureter urothelium development
ontology: BP
definition:
The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter.


go_id: GO:0072191
term: ureter smooth muscle development
ontology: BP
definition:
The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure.


go_id: GO:0072192
term: ureter epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter.


go_id: GO:0072193
term: ureter smooth muscle cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter.


go_id: GO:0072194
term: kidney smooth muscle tissue development
ontology: BP
definition:
The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure.


go_id: GO:0072195
term: kidney smooth muscle cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney.


go_id: GO:0072196
term: proximal/distal pattern formation involved in pronephric nephron development
ontology: BP
definition:
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.


go_id: GO:0072197
term: ureter morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.


go_id: GO:0072198
term: mesenchymal cell proliferation involved in ureter development
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development.


go_id: GO:0072199
term: regulation of mesenchymal cell proliferation involved in ureter development
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.


go_id: GO:0072200
term: negative regulation of mesenchymal cell proliferation involved in ureter development
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.


go_id: GO:0072201
term: negative regulation of mesenchymal cell proliferation
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.


go_id: GO:0072202
term: cell differentiation involved in metanephros development
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state.


go_id: GO:0072203
term: cell proliferation involved in metanephros development
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros.


go_id: GO:0072204
term: cell-cell signaling involved in metanephros development
ontology: BP
definition:
Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ.


go_id: GO:0072205
term: metanephric collecting duct development
ontology: BP
definition:
The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.


go_id: GO:0072206
term: metanephric juxtaglomerular apparatus development
ontology: BP
definition:
The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.


go_id: GO:0072207
term: metanephric epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.


go_id: GO:0072208
term: metanephric smooth muscle tissue development
ontology: BP
definition:
The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure.


go_id: GO:0072209
term: metanephric mesangial cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state.


go_id: GO:0072210
term: metanephric nephron development
ontology: BP
definition:
The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.


go_id: GO:0072211
term: metanephric pyramids development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts.


go_id: GO:0072212
term: regulation of transcription from RNA polymerase II promoter involved in metanephros development
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the metanephros progresses from its initial formation to the mature state.


go_id: GO:0072213
term: metanephric capsule development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.


go_id: GO:0072214
term: metanephric cortex development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros.


go_id: GO:0072215
term: regulation of metanephros development
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.


go_id: GO:0072216
term: positive regulation of metanephros development
ontology: BP
definition:
Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


go_id: GO:0072217
term: negative regulation of metanephros development
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.


go_id: GO:0072218
term: metanephric ascending thin limb development
ontology: BP
definition:
The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.


go_id: GO:0072219
term: metanephric cortical collecting duct development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex.


go_id: GO:0072220
term: metanephric descending thin limb development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle.


go_id: GO:0072221
term: metanephric distal convoluted tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.


go_id: GO:0072222
term: metanephric early distal convoluted tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive.


go_id: GO:0072223
term: metanephric glomerular mesangium development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus.


go_id: GO:0072224
term: metanephric glomerulus development
ontology: BP
definition:
The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.


go_id: GO:0072225
term: metanephric late distal convoluted tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.


go_id: GO:0072226
term: metanephric long descending thin limb bend development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros.


go_id: GO:0072227
term: metanephric macula densa development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.


go_id: GO:0072228
term: metanephric prebend segment development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.


go_id: GO:0072229
term: metanephric proximal convoluted tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule.


go_id: GO:0072230
term: metanephric proximal straight tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule.


go_id: GO:0072231
term: metanephric proximal convoluted tubule segment 1 development
ontology: BP
definition:
The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.


go_id: GO:0072232
term: metanephric proximal convoluted tubule segment 2 development
ontology: BP
definition:
The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride.


go_id: GO:0072233
term: metanephric thick ascending limb development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.


go_id: GO:0072234
term: metanephric nephron tubule development
ontology: BP
definition:
The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.


go_id: GO:0072235
term: metanephric distal tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule.


go_id: GO:0072236
term: metanephric loop of Henle development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros.


go_id: GO:0072237
term: metanephric proximal tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.


go_id: GO:0072238
term: metanephric long nephron development
ontology: BP
definition:
The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros.


go_id: GO:0072239
term: metanephric glomerulus vasculature development
ontology: BP
definition:
The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.


go_id: GO:0072240
term: metanephric DCT cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state.


go_id: GO:0072241
term: metanephric DCT cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure.


go_id: GO:0072242
term: metanephric DCT cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell.


go_id: GO:0072243
term: metanephric nephron epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.


go_id: GO:0072244
term: metanephric glomerular epithelium development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.


go_id: GO:0072245
term: metanephric glomerular parietal epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


go_id: GO:0072246
term: metanephric glomerular parietal epithelial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


go_id: GO:0072247
term: metanephric glomerular parietal epithelial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.


go_id: GO:0072248
term: metanephric glomerular visceral epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.


go_id: GO:0072249
term: metanephric glomerular visceral epithelial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.


go_id: GO:0072250
term: metanephric glomerular visceral epithelial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.


go_id: GO:0072251
term: metanephric juxtaglomerulus cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state.


go_id: GO:0072252
term: metanephric juxtaglomerulus cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure.


go_id: GO:0072253
term: metanephric juxtaglomerulus cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell.


go_id: GO:0072254
term: metanephric glomerular mesangial cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state.


go_id: GO:0072255
term: metanephric glomerular mesangial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure.


go_id: GO:0072256
term: metanephric glomerular mesangial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.


go_id: GO:0072257
term: metanephric nephron tubule epithelial cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state.


go_id: GO:0072258
term: metanephric interstitial fibroblast differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state.


go_id: GO:0072259
term: metanephric interstitial fibroblast development
ontology: BP
definition:
The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure.


go_id: GO:0072260
term: metanephric interstitial fibroblast fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast.


go_id: GO:0072261
term: metanephric extraglomerular mesangial cell proliferation involved in metanephros development
ontology: BP
definition:
The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.


go_id: GO:0072262
term: metanephric glomerular mesangial cell proliferation involved in metanephros development
ontology: BP
definition:
The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population.


go_id: GO:0072263
term: metanephric intraglomerular mesangial cell proliferation
ontology: BP
definition:
The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.


go_id: GO:0072264
term: metanephric glomerular endothelium development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.


go_id: GO:0072265
term: metanephric capsule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.


go_id: GO:0072266
term: metanephric capsule formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.


go_id: GO:0072267
term: metanephric capsule specification
ontology: BP
definition:
The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


go_id: GO:0072268
term: pattern specification involved in metanephros development
ontology: BP
definition:
Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate.


go_id: GO:0072269
term: metanephric long descending thin limb development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.


go_id: GO:0072270
term: metanephric short nephron development
ontology: BP
definition:
The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.


go_id: GO:0072271
term: metanephric short descending thin limb development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology.


go_id: GO:0072272
term: proximal/distal pattern formation involved in metanephric nephron development
ontology: BP
definition:
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).


go_id: GO:0072273
term: metanephric nephron morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.


go_id: GO:0072274
term: metanephric glomerular basement membrane development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration.


go_id: GO:0072275
term: metanephric glomerulus morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.


go_id: GO:0072276
term: metanephric glomerulus vasculature morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.


go_id: GO:0072277
term: metanephric glomerular capillary formation
ontology: BP
definition:
The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.


go_id: GO:0072278
term: metanephric comma-shaped body morphogenesis
ontology: BP
definition:
The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.


go_id: GO:0072279
term: convergent extension involved in metanephric nephron morphogenesis
ontology: BP
definition:
The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros.


go_id: GO:0072280
term: establishment of planar polarity involved in metanephric nephron morphogenesis
ontology: BP
definition:
Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros.


go_id: GO:0072281
term: mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


go_id: GO:0072282
term: metanephric nephron tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.


go_id: GO:0072283
term: metanephric renal vesicle morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells.


go_id: GO:0072284
term: metanephric S-shaped body morphogenesis
ontology: BP
definition:
The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.


go_id: GO:0072285
term: mesenchymal to epithelial transition involved in metanephric renal vesicle formation
ontology: BP
definition:
A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.


go_id: GO:0072286
term: metanephric connecting tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros.


go_id: GO:0072287
term: metanephric distal tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule.


go_id: GO:0072288
term: metanephric proximal tubule morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.


go_id: GO:0072289
term: metanephric nephron tubule formation
ontology: BP
definition:
The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros.


go_id: GO:0072290
term: epithelial cell migration involved in metanephric nephron tubule morphogenesis
ontology: BP
definition:
The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis.


go_id: GO:0072291
term: epithelial cell migration involved in metanephric distal tubule morphogenesis
ontology: BP
definition:
The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis.


go_id: GO:0072292
term: epithelial cell migration involved in metanephric proximal tubule morphogenesis
ontology: BP
definition:
The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis.


go_id: GO:0072293
term: specification of metanephric nephron tubule identity
ontology: BP
definition:
The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity.


go_id: GO:0072298
term: regulation of metanephric glomerulus development
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.


go_id: GO:0072299
term: negative regulation of metanephric glomerulus development
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.


go_id: GO:0072300
term: positive regulation of metanephric glomerulus development
ontology: BP
definition:
Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.


go_id: GO:0072301
term: regulation of metanephric glomerular mesangial cell proliferation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.


go_id: GO:0072302
term: negative regulation of metanephric glomerular mesangial cell proliferation
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.


go_id: GO:0072303
term: positive regulation of glomerular metanephric mesangial cell proliferation
ontology: BP
definition:
Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.


go_id: GO:0072304
term: regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis
ontology: BP
definition:
Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.


go_id: GO:0072305
ontology: BP
term:
negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis

definition:
Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.


go_id: GO:0072306
ontology: BP
term:
positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis

definition:
Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.


go_id: GO:0072307
term: regulation of metanephric nephron tubule epithelial cell differentiation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.


go_id: GO:0072308
term: negative regulation of metanephric nephron tubule epithelial cell differentiation
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.


go_id: GO:0072309
term: mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis
ontology: BP
definition:
The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


go_id: GO:0072310
term: glomerular epithelial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.


go_id: GO:0072311
term: glomerular epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.


go_id: GO:0072312
term: metanephric glomerular epithelial cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.


go_id: GO:0072313
term: metanephric glomerular epithelial cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.


go_id: GO:0072314
term: glomerular epithelial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.


go_id: GO:0072315
term: metanephric glomerular epithelial cell fate commitment
ontology: BP
definition:
The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.


go_id: GO:0072316
term: alpha-glucan catabolic process involved in ascospore release from ascus
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus.


go_id: GO:0072317
term: glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus
ontology: MF
definition:
Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans that contributes to the release of ascospores from the ascus.


go_id: GO:0072318
term: clathrin coat disassembly
ontology: BP
definition:
The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system.


go_id: GO:0072320
term: volume-sensitive chloride channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.


go_id: GO:0072321
term: chaperone-mediated protein transport
ontology: BP
definition:
The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins.


go_id: GO:0072322
term: protein transport across periplasmic space
ontology: BP
definition:
The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall.


go_id: GO:0072323
term: chaperone-mediated protein transport across periplasmic space
ontology: BP
definition:
The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane, mediated by chaperone molecules that bind to the transported proteins. This process has been observed in Gram-negative bacteria.


go_id: GO:0072325
term: vulval cell fate commitment
ontology: BP
definition:
The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.


go_id: GO:0072326
term: vulval cell fate determination
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.


go_id: GO:0072327
term: vulval cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.


go_id: GO:0072328
term: alkene binding
ontology: MF
definition:
Interacting selectively and non-covalently with an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.


go_id: GO:0072329
term: monocarboxylic acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.


go_id: GO:0072330
term: monocarboxylic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.


go_id: GO:0072331
term: signal transduction by p53 class mediator
ontology: BP
definition:
An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein.


go_id: GO:0072332
term: intrinsic apoptotic signaling pathway by p53 class mediator
ontology: BP
definition:
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.


go_id: GO:0072334
term: UDP-galactose transmembrane transport
ontology: BP
definition:
The directed movement of UDP-galactose across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0072335
term: regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation
ontology: BP
definition:
Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.


go_id: GO:0072336
ontology: BP
term:
negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation

definition:
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.


go_id: GO:0072337
term: modified amino acid transport
ontology: BP
definition:
The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0072338
term: cellular lactam metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.


go_id: GO:0072339
term: cellular lactam biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.


go_id: GO:0072340
term: cellular lactam catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.


go_id: GO:0072342
term: response to anion stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment.


go_id: GO:0072343
term: pancreatic stellate cell proliferation
ontology: BP
definition:
The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus.


go_id: GO:0072344
term: rescue of stalled ribosome
ontology: BP
definition:
A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex.


go_id: GO:0072345
term: NAADP-sensitive calcium-release channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts.


go_id: GO:0072346
term: cADPR-sensitive calcium-release channel activity
ontology: MF
definition:
Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts.


go_id: GO:0072347
term: response to anesthetic
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.


go_id: GO:0072348
term: sulfur compound transport
ontology: BP
definition:
The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0072350
term: tricarboxylic acid metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).


go_id: GO:0072351
term: tricarboxylic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.


go_id: GO:0072352
term: tricarboxylic acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.


go_id: GO:0072353
term: cellular age-dependent response to reactive oxygen species
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.


go_id: GO:0072354
term: histone kinase activity (H3-T3 specific)
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to the threonine-3 residue of the N-terminal tail of histone H3.


go_id: GO:0072355
term: histone H3-T3 phosphorylation
ontology: BP
definition:
The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 3 of the histone.


go_id: GO:0072356
term: chromosome passenger complex localization to kinetochore
ontology: BP
definition:
A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis.


go_id: GO:0072357
term: PTW/PP1 phosphatase complex
ontology: CC
definition:
A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.


go_id: GO:0072358
term: cardiovascular system development
ontology: BP
definition:
The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels.


go_id: GO:0072359
term: circulatory system development
ontology: BP
definition:
The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.


go_id: GO:0072360
term: vascular cord development
ontology: BP
definition:
The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis.


go_id: GO:0072361
term: regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of glycolysis by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0072362
ontology: BP
term:
regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter

definition:
Any process that modulates the frequency, rate or extent of glycolysis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0072363
ontology: BP
term:
regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter

definition:
Any process that modulates the frequency, rate or extent of glycolysis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0072364
ontology: BP
term:
regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter

definition:
Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0072365
ontology: BP
term:
regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter

definition:
Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0072366
ontology: BP
term:
regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter

definition:
Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0072367
term: regulation of lipid transport by regulation of transcription from RNA polymerase II promoter
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of lipid transport by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0072368
ontology: BP
term:
regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter

definition:
Any process that modulates the frequency, rate or extent of lipid transport by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0072369
ontology: BP
term:
regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter

definition:
Any process that modulates the frequency, rate or extent of lipid transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.


go_id: GO:0072370
term: histone H2A-S121 phosphorylation
ontology: BP
definition:
The modification of histone H2A by the addition of an phosphate group to a serine residue at position 121 of the histone.


go_id: GO:0072371
term: histone kinase activity (H2A-S121 specific)
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to the serine-121 residue of the N-terminal tail of histone H2A.


go_id: GO:0072372
term: primary cilium
ontology: CC
definition:
A cilium found on many different cell types that is typically present in a single copy per cell. A primary cilium may have a variable array of axonemal microtubules and may or may not contain molecular motors.


go_id: GO:0072374
term: carotene epsilon hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: a carotene + NADPH + O2 + H+ = a beta-ring hydroxylcarotene + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.


go_id: GO:0072375
term: medium-term memory
ontology: BP
definition:
The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).


go_id: GO:0072376
term: protein activation cascade
ontology: BP
definition:
A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.


go_id: GO:0072377
term: blood coagulation, common pathway
ontology: BP
definition:
A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.


go_id: GO:0072378
term: blood coagulation, fibrin clot formation
ontology: BP
definition:
A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.


go_id: GO:0072379
term: ER membrane insertion complex
ontology: CC
definition:
A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast.


go_id: GO:0072380
term: TRC complex
ontology: CC
definition:
An ER membrane insertion complex that contains subunits that recognize two types of transmembrane domain signals. In budding yeast the complex contains Get4p, Get5p, Sgt2p, and at least two heat shock proteins (HSPs).


go_id: GO:0072381
ontology: BP
term:
positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation

definition:
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.


go_id: GO:0072382
term: minus-end-directed vesicle transport along microtubule
ontology: BP
definition:
The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.


go_id: GO:0072383
term: plus-end-directed vesicle transport along microtubule
ontology: BP
definition:
The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.


