# go_term

go_id: GO:0033779
term: 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H(+) + NADPH + O(2) = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H(2)O + NADP(+).


go_id: GO:0033780
term: taurochenodeoxycholate 6alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O.


go_id: GO:0033781
term: cholesterol 24-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+).


go_id: GO:0033782
term: 24-hydroxycholesterol 7alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: (24R)-cholest-5-ene-3beta,24-diol + H(+) + NADPH + O(2) = (24R)-7alpha,24-dihydroxycholesterol + H(2)O + NADP(+).


go_id: GO:0033783
term: 25-hydroxycholesterol 7alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O.


go_id: GO:0033784
term: senecionine N-oxygenase activity
ontology: MF
definition:
Catalysis of the reaction: H(+) + NADPH + O(2) + senecionine = H(2)O + NADP(+) + senecionine N-oxide.


go_id: GO:0033787
term: cyanocobalamin reductase (cyanide-eliminating) activity
ontology: MF
definition:
Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP(+) = cyanocob(III)alamin + H(+) + NADPH.


go_id: GO:0033788
term: leucoanthocyanidin reductase activity
ontology: MF
definition:
Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.


go_id: GO:0033789
term: phenylacetyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2 1,4-benzoquinone + H(2)O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA.


go_id: GO:0033790
term: hydroxymethylfurfural reductase activity
ontology: MF
definition:
Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+.


go_id: GO:0033791
term: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.


go_id: GO:0033792
term: bile-acid 7alpha-dehydroxylase activity
ontology: MF
definition:
Catalysis of the reactions: deoxycholate + FAD + H2O = cholate + FADH2, and lithocholate + FAD + H2O = chenodeoxycholate + FADH2.


go_id: GO:0033793
term: aureusidin synthase activity
ontology: MF
definition:
Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O.


go_id: GO:0033794
term: sarcosine reductase activity
ontology: MF
definition:
Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin.


go_id: GO:0033795
term: betaine reductase activity
ontology: MF
definition:
Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin.


go_id: GO:0033799
term: myricetin 3'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.


go_id: GO:0033800
term: isoflavone 7-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.


go_id: GO:0033801
term: vitexin 2''-O-rhamnoside 7-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside.


go_id: GO:0033802
term: isoliquiritigenin 2'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+).


go_id: GO:0033803
term: kaempferol 4'-O-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H(+) + kaempferide.


go_id: GO:0052730
term: sarcosine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.


go_id: GO:0052729
term: dimethylglycine N-methyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine.


go_id: GO:0033807
term: icosanoyl-CoA synthase activity
ontology: MF
definition:
Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+.


go_id: GO:0033808
term: 6'-deoxychalcone synthase activity
ontology: MF
definition:
Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O.


go_id: GO:0033809
term: anthocyanin 6''-O-malonyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside).


go_id: GO:0033810
term: anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin.


go_id: GO:0033811
term: flavonol-3-O-triglucoside O-coumaroyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside].


go_id: GO:0033814
term: propanoyl-CoA C-acyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.


go_id: GO:0033816
term: diaminobutyrate acetyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H(+).


go_id: GO:0033817
term: beta-ketoacyl-acyl-carrier-protein synthase II activity
ontology: MF
definition:
Catalysis of the reaction: (Z)-hexadec-11-enoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].


go_id: GO:0033818
term: beta-ketoacyl-acyl-carrier-protein synthase III activity
ontology: MF
definition:
Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2.


go_id: GO:0033819
term: lipoyl(octanoyl) transferase activity
ontology: MF
definition:
Catalysis of the reaction: octanoyl-[acyl-carrier protein] + protein = protein N6-(octanoyl)lysine + acyl-carrier protein.


go_id: GO:0033820
term: DNA alpha-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.


go_id: GO:0033821
term: DNA beta-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.


go_id: GO:0033822
term: glucosyl-DNA beta-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA.


go_id: GO:0033823
term: procollagen glucosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen.


go_id: GO:0033824
term: alternansucrase activity
ontology: MF
definition:
Catalysis of the transfer of an alpha-D-glucosyl residue from sucrose to alternately the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages.


go_id: GO:0033825
term: oligosaccharide 4-alpha-D-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides.


go_id: GO:0033826
term: xyloglucan 4-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage.


go_id: GO:0033827
term: high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum.


go_id: GO:0033828
term: glucosylglycerol-phosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H(+).


go_id: GO:0033829
term: O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor.


go_id: GO:0033830
term: Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline.


go_id: GO:0033832
term: alpha,alpha-trehalose phosphorylase (configuration-retaining) activity
ontology: MF
definition:
Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate.


go_id: GO:0033835
term: flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside].


go_id: GO:0033837
term: anthocyanin 3'-O-beta-glucosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside.


go_id: GO:0033838
term: flavonol-3-O-glucoside glucosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside.


go_id: GO:0033839
term: flavonol-3-O-glycoside glucosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside.


go_id: GO:0033841
term: 6G-fructosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0).


go_id: GO:0033842
term: N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group.


go_id: GO:0033843
term: xyloglucan 6-xylosyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage.


go_id: GO:0033844
term: galactose-6-sulfurylase activity
ontology: MF
definition:
Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues.


go_id: GO:0033845
term: hydroxymethylfurfural reductase (NADPH) activity
ontology: MF
definition:
Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+.


go_id: GO:0033846
term: adenosyl-fluoride synthase activity
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine.


go_id: GO:0033848
term: N2-(2-carboxyethyl)arginine synthase activity
ontology: MF
definition:
Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H(+) + phosphate.


go_id: GO:0033849
term: chrysanthemyl diphosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate.


go_id: GO:0033850
term: Z-farnesyl diphosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate.


go_id: GO:0033852
term: thyroid-hormone transaminase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate.


go_id: GO:0033855
term: nicotianamine aminotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate.


go_id: GO:0033856
term: pyridoxine 5'-phosphate synthase activity
ontology: MF
definition:
Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H(2)O + H(+) + phosphate + pyridoxine 5'-phosphate.


go_id: GO:0033857
term: diphosphoinositol-pentakisphosphate kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.


go_id: GO:0033858
term: N-acetylgalactosamine kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate.


go_id: GO:0033859
term: furaldehyde metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass.


go_id: GO:0033863
term: ribose 1,5-bisphosphate phosphokinase activity
ontology: MF
definition:
Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H(+).


go_id: GO:0033865
term: nucleoside bisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0033866
term: nucleoside bisphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0033867
term: Fas-activated serine/threonine kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein.


go_id: GO:0033868
term: Goodpasture-antigen-binding protein kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein.


go_id: GO:0033869
term: nucleoside bisphosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0033870
term: thiol sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate.


go_id: GO:0033871
term: [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S.


go_id: GO:0033872
term: [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.


go_id: GO:0033873
term: petromyzonol sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H(+).


go_id: GO:0033874
term: scymnol sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H(+).


go_id: GO:0033875
term: ribonucleoside bisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0033876
term: glycochenodeoxycholate sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H(+).


go_id: GO:0033877
term: succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity
ontology: MF
definition:
Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate.


go_id: GO:0033878
term: hormone-sensitive lipase activity
ontology: MF
definition:
Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate.


go_id: GO:0033879
term: acetylajmaline esterase activity
ontology: MF
definition:
Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate.


go_id: GO:0033885
term: 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate.


go_id: GO:0033886
term: cellulose-polysulfatase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin.


go_id: GO:0033887
term: chondro-4-sulfatase activity
ontology: MF
definition:
Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate.


go_id: GO:0033888
term: chondro-6-sulfatase activity
ontology: MF
definition:
Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate.


go_id: GO:0033889
term: N-sulfoglucosamine-3-sulfatase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.


go_id: GO:0033890
term: ribonuclease D activity
ontology: MF
definition:
Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.


go_id: GO:0033891
term: CC-preferring endodeoxyribonuclease activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC.


go_id: GO:0033893
term: ribonuclease IV activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.


go_id: GO:0033895
term: ribonuclease [poly-(U)-specific] activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.


go_id: GO:0033896
term: ribonuclease IX activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.


go_id: GO:0033897
term: ribonuclease T2 activity
ontology: MF
definition:
Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.


go_id: GO:0033899
term: ribonuclease U2 activity
ontology: MF
definition:
Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates.


go_id: GO:0033900
term: ribonuclease F activity
ontology: MF
definition:
Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups.


go_id: GO:0033902
term: rRNA endonuclease activity
ontology: MF
definition:
Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes.


go_id: GO:0052861
term: glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group
ontology: MF
definition:
Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.


go_id: GO:0052862
term: glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group
ontology: MF
definition:
Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.


go_id: GO:0033906
term: hyaluronoglucuronidase activity
ontology: MF
definition:
Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.


go_id: GO:0033908
term: beta-L-rhamnosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides.


go_id: GO:0033909
term: fucoidanase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate.


go_id: GO:0033910
term: glucan 1,4-alpha-maltotetraohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends.


go_id: GO:0033911
term: mycodextranase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds.


go_id: GO:0033912
term: 2,6-beta-fructan 6-levanbiohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain.


go_id: GO:0033914
term: xylan 1,3-beta-xylosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans.


go_id: GO:0033916
term: beta-agarase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product.


go_id: GO:0033918
term: kappa-carrageenase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans.


go_id: GO:0033920
term: 6-phospho-beta-galactosidase activity
ontology: MF
definition:
Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.


go_id: GO:0033921
term: capsular-polysaccharide endo-1,3-alpha-galactosidase activity
ontology: MF
definition:
Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide.


go_id: GO:0033923
term: glucan 1,6-alpha-isomaltosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains.


go_id: GO:0033924
term: dextran 1,6-alpha-isomaltotriosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.


go_id: GO:0033925
term: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.


go_id: GO:0033926
term: glycopeptide alpha-N-acetylgalactosaminidase activity
ontology: MF
definition:
Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine.


go_id: GO:0033927
term: glucan 1,4-alpha-maltohexaosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends.


go_id: GO:0033928
term: mannan 1,4-mannobiosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends.


go_id: GO:0033929
term: blood-group-substance endo-1,4-beta-galactosidase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances.


go_id: GO:0033931
term: endogalactosaminidase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine).


go_id: GO:0033932
term: 1,3-alpha-L-fucosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins.


go_id: GO:0033933
term: branched-dextran exo-1,2-alpha-glucosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose.


go_id: GO:0033934
term: glucan 1,4-alpha-maltotriohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends.


go_id: GO:0033935
term: oligoxyloglucan beta-glycosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.


go_id: GO:0033937
term: 3-deoxy-2-octulosonidase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides.


go_id: GO:0033938
term: 1,6-alpha-L-fucosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.


go_id: GO:0033939
term: xylan alpha-1,2-glucuronosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans.


go_id: GO:0033941
term: mannan exo-1,2-1,6-alpha-mannosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose.


go_id: GO:0033942
term: 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan.


go_id: GO:0033943
term: galactan 1,3-beta-galactosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans.


go_id: GO:0033944
term: beta-galactofuranosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.


go_id: GO:0033945
term: oligoxyloglucan reducing-end-specific cellobiohydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.


go_id: GO:0033946
term: xyloglucan-specific endo-beta-1,4-glucanase activity
ontology: MF
definition:
Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan.


go_id: GO:0033947
term: mannosylglycoprotein endo-beta-mannosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences.


go_id: GO:0033948
term: fructan beta-(2,1)-fructosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans.


go_id: GO:0033949
term: fructan beta-(2,6)-fructosidase activity
ontology: MF
definition:
Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans.


go_id: GO:0033950
term: xyloglucan-specific exo-beta-1,4-glucanase activity
ontology: MF
definition:
Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan.


go_id: GO:0033951
term: oligosaccharide reducing-end xylanase activity
ontology: MF
definition:
Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides.


go_id: GO:0033952
term: iota-carrageenase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans.


go_id: GO:0033953
term: alpha-agarase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.


go_id: GO:0033954
term: alpha-neoagaro-oligosaccharide hydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose.


go_id: GO:0033955
term: mitochondrial DNA inheritance
ontology: BP
definition:
The process in which copies of the mitochondrial genome are distributed into daughter mitochondria upon mitochondrial fission.


go_id: GO:0033956
term: beta-apiosyl-beta-glucosidase activity
ontology: MF
definition:
Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose.


go_id: GO:0033957
term: lambda-carrageenase activity
ontology: MF
definition:
Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S.


go_id: GO:0033959
term: deoxyribodipyrimidine endonucleosidase activity
ontology: MF
definition:
Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue.


go_id: GO:0033962
term: cytoplasmic mRNA processing body assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.


go_id: GO:0033963
term: cholesterol-5,6-oxide hydrolase activity
ontology: MF
definition:
Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol.


go_id: GO:0033964
term: glycosphingolipid deacylase activity
ontology: MF
definition:
Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.


go_id: GO:0033965
term: aculeacin-A deacylase activity
ontology: MF
definition:
Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain.


go_id: GO:0033968
term: glutaryl-7-aminocephalosporanic-acid acylase activity
ontology: MF
definition:
Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate.


go_id: GO:0033969
term: gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H(2)O = 4-aminobutanoate + L-glutamate.


go_id: GO:0033971
term: hydroxyisourate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+).


go_id: GO:0033976
term: 2-haloacid dehalogenase (configuration-inverting) activity
ontology: MF
definition:
Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.


go_id: GO:0033977
term: 2-haloacid dehalogenase (configuration-retaining) activity
ontology: MF
definition:
Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.


go_id: GO:0033982
term: 3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ontology: MF
definition:
Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO(2).


go_id: GO:0033984
term: indole-3-glycerol-phosphate lyase activity
ontology: MF
definition:
Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate.


go_id: GO:0033986
term: response to methanol
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.


go_id: GO:0033988
term: bile-acid 7alpha-dehydratase activity
ontology: MF
definition:
Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(2)O.


go_id: GO:0033989
term: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
ontology: MF
definition:
Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O.


go_id: GO:0033991
term: aldos-2-ulose dehydratase activity
ontology: MF
definition:
Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one.


go_id: GO:0033992
term: 1,5-anhydro-D-fructose dehydratase activity
ontology: MF
definition:
Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O.


go_id: GO:0033993
term: response to lipid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.


go_id: GO:0033994
term: glucuronan lyase activity
ontology: MF
definition:
Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.


go_id: GO:0033995
term: anhydrosialidase activity
ontology: MF
definition:
Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.


go_id: GO:0033996
term: levan fructotransferase (DFA-IV-forming) activity
ontology: MF
definition:
Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide.


go_id: GO:0033997
term: inulin fructotransferase (DFA-I-forming) activity
ontology: MF
definition:
Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.


go_id: GO:0033998
term: inulin fructotransferase (DFA-III-forming) activity
ontology: MF
definition:
Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.


go_id: GO:0033999
term: chondroitin B lyase activity
ontology: MF
definition:
Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate.


go_id: GO:0034000
term: chondroitin-sulfate-ABC endolyase activity
ontology: MF
definition:
Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides.


go_id: GO:0034001
term: chondroitin-sulfate-ABC exolyase activity
ontology: MF
definition:
Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments.


go_id: GO:0034004
term: germacradienol synthase activity
ontology: MF
definition:
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate.


go_id: GO:0034005
term: germacrene-A synthase activity
ontology: MF
definition:
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.


go_id: GO:0034014
term: response to triglyceride
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.


go_id: GO:0034016
term: polyenoic fatty acid isomerase activity
ontology: MF
definition:
Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate.


go_id: GO:0034017
term: trans-2-decenoyl-acyl-carrier-protein isomerase activity
ontology: MF
definition:
Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein].


go_id: GO:0034018
term: ascopyrone tautomerase activity
ontology: MF
definition:
Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose.


go_id: GO:0034021
term: response to silicon dioxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.


go_id: GO:0034023
term: 5-(carboxyamino)imidazole ribonucleotide mutase activity
ontology: MF
definition:
Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate.


go_id: GO:0034024
term: glutamate-putrescine ligase activity
ontology: MF
definition:
Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H(+) + phosphate.


go_id: GO:0034025
term: D-aspartate ligase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate.


go_id: GO:0034026
term: L-amino-acid alpha-ligase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid.


go_id: GO:0034027
term: (carboxyethyl)arginine beta-lactam-synthase activity
ontology: MF
definition:
Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H(+).


go_id: GO:0034028
term: 5-(carboxyamino)imidazole ribonucleotide synthase activity
ontology: MF
definition:
Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H(+) + phosphate.


go_id: GO:0034029
term: 2-oxoglutarate carboxylase activity
ontology: MF
definition:
Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H(+) + oxalosuccinate + phosphate.


go_id: GO:0034030
term: ribonucleoside bisphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034031
term: ribonucleoside bisphosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034032
term: purine nucleoside bisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034033
term: purine nucleoside bisphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034034
term: purine nucleoside bisphosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034035
term: purine ribonucleoside bisphosphate metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034036
term: purine ribonucleoside bisphosphate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034037
term: purine ribonucleoside bisphosphate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.


go_id: GO:0034039
term: 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
ontology: MF
definition:
Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar.


go_id: GO:0034040
term: lipid-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out).


go_id: GO:0034041
term: sterol-transporting ATPase activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out).


go_id: GO:0034042
term: 5-formyluracil DNA N-glycosylase activity
ontology: MF
definition:
Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.


go_id: GO:0034043
term: 5-hydroxymethyluracil DNA N-glycosylase activity
ontology: MF
definition:
Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.


go_id: GO:0034044
term: exomer complex
ontology: CC
definition:
A protein complex that forms a coat structure on vesicles involved in exocytosis of proteins from the trans-Golgi network to the cell surface; in Saccharomyces, the complex contains Chs5p, Chs6p, and Chs6p paralogues.


go_id: GO:0034050
term: host programmed cell death induced by symbiont
ontology: BP
definition:
Cell death in a host resulting from activation of host endogenous cellular processes after direct or indirect interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). An example of direct interaction is contact with penetrating hyphae of a fungus; an example of indirect interaction is encountering symbiont-secreted molecules.


go_id: GO:0034051
term: negative regulation of plant-type hypersensitive response
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant.


go_id: GO:0034052
term: positive regulation of plant-type hypersensitive response
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant.


go_id: GO:0034053
term: modulation by symbiont of host defense-related programmed cell death
ontology: BP
definition:
Any process in which an organism modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0034054
term: negative regulation by symbiont of host defense-related programmed cell death
ontology: BP
definition:
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0034055
term: positive regulation by symbiont of host defense-related programmed cell death
ontology: BP
definition:
Any process in which an organism activates or increases the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0034056
term: estrogen response element binding
ontology: MF
definition:
Interacting selectively and non-covalently with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.


go_id: GO:0034057
term: RNA strand-exchange activity
ontology: MF
definition:
Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.


go_id: GO:0034059
term: response to anoxia
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.


go_id: GO:0034061
term: DNA polymerase activity
ontology: MF
definition:
Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group.


go_id: GO:0034062
term: RNA polymerase activity
ontology: MF
definition:
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.


go_id: GO:0034063
term: stress granule assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.


go_id: GO:0034064
term: Tor2-Mei2-Ste11 complex
ontology: CC
definition:
A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast.


go_id: GO:0034065
term: replication fork processing at rDNA locus
ontology: BP
definition:
The process in which a DNA replication fork that has stalled at the rDNA replication fork barrier (RFB) is repaired and replication is restarted.


go_id: GO:0034066
term: RIC1-RGP1 guanyl-nucleotide exchange factor complex
ontology: CC
definition:
A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi.


go_id: GO:0034067
term: protein localization to Golgi apparatus
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.


go_id: GO:0034068
term: aminoglycoside nucleotidyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.


go_id: GO:0034070
term: aminoglycoside 1-N-acetyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring.


go_id: GO:0034075
term: arabidiol synthase activity
ontology: MF
definition:
Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol).


go_id: GO:0034077
term: butanediol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


go_id: GO:0034078
term: butanediol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


go_id: GO:0034079
term: butanediol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


go_id: GO:0034080
term: CENP-A containing nucleosome assembly
ontology: BP
definition:
The formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres,  and the central core in modular centromeres.


go_id: GO:0034082
term: type II polyketide synthase complex
ontology: CC
definition:
A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction.


go_id: GO:0034085
term: establishment of sister chromatid cohesion
ontology: BP
definition:
The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase.


go_id: GO:0034086
term: maintenance of sister chromatid cohesion
ontology: BP
definition:
The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate.


go_id: GO:0034087
term: establishment of mitotic sister chromatid cohesion
ontology: BP
definition:
The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.


go_id: GO:0034088
term: maintenance of mitotic sister chromatid cohesion
ontology: BP
definition:
The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.


go_id: GO:0034089
term: establishment of meiotic sister chromatid cohesion
ontology: BP
definition:
The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle.


go_id: GO:0034090
term: maintenance of meiotic sister chromatid cohesion
ontology: BP
definition:
The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.


go_id: GO:0034091
term: regulation of maintenance of sister chromatid cohesion
ontology: BP
definition:
Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained.


go_id: GO:0034092
term: negative regulation of maintenance of sister chromatid cohesion
ontology: BP
definition:
Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained.


go_id: GO:0034093
term: positive regulation of maintenance of sister chromatid cohesion
ontology: BP
definition:
Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained.


go_id: GO:0034094
term: regulation of maintenance of meiotic sister chromatid cohesion
ontology: BP
definition:
Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


go_id: GO:0034095
term: negative regulation of maintenance of meiotic sister chromatid cohesion
ontology: BP
definition:
Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


go_id: GO:0034096
term: positive regulation of maintenance of meiotic sister chromatid cohesion
ontology: BP
definition:
Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


go_id: GO:0034097
term: response to cytokine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.


go_id: GO:0034098
term: VCP-NPL4-UFD1 AAA ATPase complex
ontology: CC
definition:
A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry).


go_id: GO:0034099
term: luminal surveillance complex
ontology: CC
definition:
A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins.


go_id: GO:0034107
term: negative regulation of erythrocyte clearance
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance.


go_id: GO:0034111
term: negative regulation of homotypic cell-cell adhesion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.


go_id: GO:0034112
term: positive regulation of homotypic cell-cell adhesion
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.


go_id: GO:0034115
term: negative regulation of heterotypic cell-cell adhesion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion.


go_id: GO:0034116
term: positive regulation of heterotypic cell-cell adhesion
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.


go_id: GO:0034119
term: negative regulation of erythrocyte aggregation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation.


go_id: GO:0034122
term: negative regulation of toll-like receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.


go_id: GO:0034123
term: positive regulation of toll-like receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway.


go_id: GO:0034124
term: regulation of MyD88-dependent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.


go_id: GO:0034125
term: negative regulation of MyD88-dependent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.


go_id: GO:0034126
term: positive regulation of MyD88-dependent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.


go_id: GO:0034127
term: regulation of MyD88-independent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.


go_id: GO:0034128
term: negative regulation of MyD88-independent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.


go_id: GO:0034129
term: positive regulation of MyD88-independent toll-like receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.


go_id: GO:0034131
term: regulation of toll-like receptor 1 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway.


go_id: GO:0034132
term: negative regulation of toll-like receptor 1 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway.


go_id: GO:0034133
term: positive regulation of toll-like receptor 1 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway.


go_id: GO:0034135
term: regulation of toll-like receptor 2 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway.


go_id: GO:0034136
term: negative regulation of toll-like receptor 2 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway.


go_id: GO:0034137
term: positive regulation of toll-like receptor 2 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.


go_id: GO:0034139
term: regulation of toll-like receptor 3 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway.


go_id: GO:0034140
term: negative regulation of toll-like receptor 3 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway.


go_id: GO:0034141
term: positive regulation of toll-like receptor 3 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.


go_id: GO:0034143
term: regulation of toll-like receptor 4 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway.


go_id: GO:0034144
term: negative regulation of toll-like receptor 4 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.


go_id: GO:0034145
term: positive regulation of toll-like receptor 4 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.


go_id: GO:0034147
term: regulation of toll-like receptor 5 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway.


go_id: GO:0034148
term: negative regulation of toll-like receptor 5 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway.


go_id: GO:0034149
term: positive regulation of toll-like receptor 5 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway.


go_id: GO:0034151
term: regulation of toll-like receptor 6 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway.


go_id: GO:0034152
term: negative regulation of toll-like receptor 6 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway.


go_id: GO:0034153
term: positive regulation of toll-like receptor 6 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway.


go_id: GO:0034155
term: regulation of toll-like receptor 7 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


go_id: GO:0034156
term: negative regulation of toll-like receptor 7 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


go_id: GO:0034157
term: positive regulation of toll-like receptor 7 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


go_id: GO:0034159
term: regulation of toll-like receptor 8 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway.


go_id: GO:0034160
term: negative regulation of toll-like receptor 8 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway.


go_id: GO:0034161
term: positive regulation of toll-like receptor 8 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway.


go_id: GO:0034163
term: regulation of toll-like receptor 9 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway.


go_id: GO:0034164
term: negative regulation of toll-like receptor 9 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway.


go_id: GO:0034165
term: positive regulation of toll-like receptor 9 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.


go_id: GO:0034167
term: regulation of toll-like receptor 10 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway.


go_id: GO:0034168
term: negative regulation of toll-like receptor 10 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway.


go_id: GO:0034169
term: positive regulation of toll-like receptor 10 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway.


go_id: GO:0034171
term: regulation of toll-like receptor 11 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


go_id: GO:0034172
term: negative regulation of toll-like receptor 11 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


go_id: GO:0034173
term: positive regulation of toll-like receptor 11 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


go_id: GO:0034175
term: regulation of toll-like receptor 12 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway.


go_id: GO:0034176
term: negative regulation of toll-like receptor 12 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway.


go_id: GO:0034177
term: positive regulation of toll-like receptor 12 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway.


go_id: GO:0034179
term: regulation of toll-like receptor 13 signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway.


go_id: GO:0034180
term: negative regulation of toll-like receptor 13 signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway.


go_id: GO:0034181
term: positive regulation of toll-like receptor 13 signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway.


go_id: GO:0034182
term: regulation of maintenance of mitotic sister chromatid cohesion
ontology: BP
definition:
Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.


go_id: GO:0034183
term: negative regulation of maintenance of mitotic sister chromatid cohesion
ontology: BP
definition:
Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.


go_id: GO:0034184
term: positive regulation of maintenance of mitotic sister chromatid cohesion
ontology: BP
definition:
Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.


go_id: GO:0034185
term: apolipoprotein binding
ontology: MF
definition:
Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex.


go_id: GO:0034188
term: apolipoprotein A-I receptor activity
ontology: MF
definition:
Combining with apolipoprotein A-I and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


go_id: GO:0034189
term: very-low-density lipoprotein particle binding
ontology: MF
definition:
Interacting selectively and non-covalently with a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm.


go_id: GO:0034194
term: D-galactonate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid.


go_id: GO:0034195
term: L-galactonate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid.


go_id: GO:0034196
term: acylglycerol transport
ontology: BP
definition:
The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids.


go_id: GO:0034197
term: triglyceride transport
ontology: BP
definition:
The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.


go_id: GO:0034198
term: cellular response to amino acid starvation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.


go_id: GO:0034200
term: D,D-heptose 1,7-bisphosphate phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate.


go_id: GO:0034201
term: response to oleic acid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.


go_id: GO:0034202
term: glycolipid-translocating activity
ontology: MF
definition:
Catalysis of the movement of glycolipids from one membrane face to the other (glycolipid 'flippase' activity).


go_id: GO:0034203
term: glycolipid translocation
ontology: BP
definition:
The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


go_id: GO:0034204
term: lipid translocation
ontology: BP
definition:
The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.


go_id: GO:0034206
term: enhanceosome
ontology: CC
definition:
A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation.


go_id: GO:0034207
term: steroid acetylation
ontology: BP
definition:
The addition of an acetyl group to a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


go_id: GO:0034208
term: steroid deacetylation
ontology: BP
definition:
The removal of an acetyl group from a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


go_id: GO:0034209
term: sterol acetylation
ontology: BP
definition:
The addition of an acetyl group to a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


go_id: GO:0034210
term: sterol deacetylation
ontology: BP
definition:
The removal of an acetyl group from a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


go_id: GO:0034211
term: GTP-dependent protein kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of GTP.


go_id: GO:0034212
term: peptide N-acetyltransferase activity
ontology: MF
definition:
Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.


go_id: GO:0034213
term: quinolinate catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.


go_id: GO:0034214
term: protein hexamerization
ontology: BP
definition:
The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.


go_id: GO:0034215
term: thiamine:proton symporter activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in).


go_id: GO:0034216
term: high-affinity thiamine:proton symporter activity
ontology: MF
definition:
Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


go_id: GO:0034217
term: ascospore wall chitin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.


go_id: GO:0034218
term: ascospore wall chitin metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.


go_id: GO:0034219
term: carbohydrate transmembrane transport
ontology: BP
definition:
The process in which a carbohydrate is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034220
term: ion transmembrane transport
ontology: BP
definition:
A process in which an ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034221
term: fungal-type cell wall chitin biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells.


go_id: GO:0034222
term: regulation of cell wall chitin metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall.


go_id: GO:0034223
term: regulation of ascospore wall chitin biosynthetic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin.


go_id: GO:0034224
term: cellular response to zinc ion starvation
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.


go_id: GO:0034225
term: regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation
ontology: BP
definition:
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions.


go_id: GO:0034228
term: ethanolamine transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of ethanolamine from one side of the membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.


go_id: GO:0034229
term: ethanolamine transport
ontology: BP
definition:
The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.


go_id: GO:0034230
term: enkephalin processing
ontology: BP
definition:
The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.


go_id: GO:0034231
term: islet amyloid polypeptide processing
ontology: BP
definition:
The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).


go_id: GO:0034232
term: ascospore wall chitin catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.


go_id: GO:0034233
term: regulation of cell wall chitin catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin.


go_id: GO:0034234
term: regulation of ascospore wall chitin catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin.


go_id: GO:0034235
term: GPI anchor binding
ontology: MF
definition:
Interacting selectively and non-covalently with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.


go_id: GO:0034236
term: protein kinase A catalytic subunit binding
ontology: MF
definition:
Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.


go_id: GO:0034237
term: protein kinase A regulatory subunit binding
ontology: MF
definition:
Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A.


go_id: GO:0034242
term: negative regulation of syncytium formation by plasma membrane fusion
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.


go_id: GO:0034243
term: regulation of transcription elongation from RNA polymerase II promoter
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.


go_id: GO:0034244
term: negative regulation of transcription elongation from RNA polymerase II promoter
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.


go_id: GO:0034245
term: mitochondrial DNA-directed RNA polymerase complex
ontology: CC
definition:
A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form.


go_id: GO:0034246
term: mitochondrial RNA polymerase binding promoter specificity activity
ontology: MF
definition:
Interacting selectively and non-covalently with a mitochondrial RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of mitochondrial promoter DNA sequence motifs.


go_id: GO:0034247
term: snoRNA splicing
ontology: BP
definition:
The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.


go_id: GO:0034248
term: regulation of cellular amide metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.


go_id: GO:0034249
term: negative regulation of cellular amide metabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.


go_id: GO:0034250
term: positive regulation of cellular amide metabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.


go_id: GO:0034251
term: regulation of cellular amide catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.


go_id: GO:0034252
term: negative regulation of cellular amide catabolic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.


go_id: GO:0034253
term: positive regulation of cellular amide catabolic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.


go_id: GO:0034254
term: regulation of urea catabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea.


go_id: GO:0034255
term: regulation of urea metabolic process
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea.


go_id: GO:0034256
term: chlorophyll(ide) b reductase activity
ontology: MF
definition:
Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+.


go_id: GO:0034257
term: nicotinamide riboside transmembrane transporter activity
ontology: MF
definition:
Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.


go_id: GO:0034258
term: nicotinamide riboside transport
ontology: BP
definition:
The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034263
term: autophagy in response to ER overload
ontology: BP
definition:
The process in which cells digest parts of their own cytoplasm in response to the accumulation of misfolded proteins in the endoplasmic reticulum.


go_id: GO:0034265
term: isopentenyl adenine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.


go_id: GO:0034266
term: isopentenyl adenine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine.


go_id: GO:0034267
term: discadenine metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.


go_id: GO:0034268
term: discadenine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.


go_id: GO:0034269
term: discadenine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.


go_id: GO:0034270
term: CVT complex
ontology: CC
definition:
A protein complex that is involved in the CVT pathway. In budding yeast, the CVT complex consists of multimers of preApe1p.


go_id: GO:0034271
term: phosphatidylinositol 3-kinase complex, class III, type I
ontology: CC
definition:
A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p.


go_id: GO:0034272
term: phosphatidylinositol 3-kinase complex, class III, type II
ontology: CC
definition:
A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p.


go_id: GO:0034274
term: Atg12-Atg5-Atg16 complex
ontology: CC
definition:
A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p.


go_id: GO:0034276
term: kynurenic acid biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.


go_id: GO:0034280
term: ent-sandaracopimaradiene synthase activity
ontology: MF
definition:
Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate.


go_id: GO:0034284
term: response to monosaccharide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.


go_id: GO:0034285
term: response to disaccharide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.


go_id: GO:0034286
term: response to maltose
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.


go_id: GO:0034287
term: detection of monosaccharide stimulus
ontology: BP
definition:
The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal.


go_id: GO:0034288
term: detection of disaccharide stimulus
ontology: BP
definition:
The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal.


go_id: GO:0034289
term: detection of maltose stimulus
ontology: BP
definition:
The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal.


go_id: GO:0034290
term: holin activity
ontology: MF
definition:
A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting channel activity directly or indirectly allows murein hydrolyases to access their cell wall substrate.


go_id: GO:0034291
term: canonical holin activity
ontology: MF
definition:
A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting channel activity directly allows release of a fully-folded phage-encoded endolysin (murein-degradase) from the cell.


go_id: GO:0034292
term: pinholin activity
ontology: MF
definition:
A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting ion channel activity indirectly allows endolysin (murein hydrolyases) to access their cell wall substrate by collapsing the proton motive force (PMF) across the membrane, allowing the endolysin to fold to an active form and hydrolyze bonds in the peptidoglycan cell wall.


go_id: GO:0034294
term: sexual spore wall assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.


go_id: GO:0034295
term: basidiospore formation
ontology: BP
definition:
The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium.


go_id: GO:0034296
term: zygospore formation
ontology: BP
definition:
The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away.


go_id: GO:0034297
term: oidium formation
ontology: BP
definition:
The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus.


go_id: GO:0034298
term: arthrospore formation
ontology: BP
definition:
The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation.


go_id: GO:0034299
term: reproductive blastospore formation
ontology: BP
definition:
The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota.


go_id: GO:0034300
term: sporangiospore formation
ontology: BP
definition:
The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.


go_id: GO:0034301
term: endospore formation
ontology: BP
definition:
The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions.


go_id: GO:0034302
term: akinete formation
ontology: BP
definition:
The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria.


go_id: GO:0034303
term: myxospore formation
ontology: BP
definition:
The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria.


go_id: GO:0034304
term: actinomycete-type spore formation
ontology: BP
definition:
The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales.


go_id: GO:0034305
term: regulation of asexual sporulation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis.


go_id: GO:0034306
term: regulation of sexual sporulation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae.


go_id: GO:0034307
term: regulation of ascospore formation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae.


go_id: GO:0034308
term: primary alcohol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.


go_id: GO:0034309
term: primary alcohol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.


go_id: GO:0034310
term: primary alcohol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.


go_id: GO:0034311
term: diol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic.


go_id: GO:0034312
term: diol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.


go_id: GO:0034313
term: diol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.


go_id: GO:0034314
term: Arp2/3 complex-mediated actin nucleation
ontology: BP
definition:
The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.


go_id: GO:0034315
term: regulation of Arp2/3 complex-mediated actin nucleation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.


go_id: GO:0034316
term: negative regulation of Arp2/3 complex-mediated actin nucleation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.


go_id: GO:0034329
term: cell junction assembly
ontology: BP
definition:
A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.


go_id: GO:0034330
term: cell junction organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.


go_id: GO:0034331
term: cell junction maintenance
ontology: BP
definition:
The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.


go_id: GO:0034332
term: adherens junction organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


go_id: GO:0034333
term: adherens junction assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


go_id: GO:0034334
term: adherens junction maintenance
ontology: BP
definition:
The maintenance of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


go_id: GO:0034336
term: misfolded RNA binding
ontology: MF
definition:
Interacting selectively and non-covalently with an RNA molecule that has assumed an incorrect conformation.


go_id: GO:0034337
term: RNA folding
ontology: BP
definition:
The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.


go_id: GO:0034338
term: short-chain carboxylesterase activity
ontology: MF
definition:
Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms.


go_id: GO:0034340
term: response to type I interferon
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


go_id: GO:0034341
term: response to interferon-gamma
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.


go_id: GO:0034342
term: response to type III interferon
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034343
term: type III interferon production
ontology: BP
definition:
The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034344
term: regulation of type III interferon production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034345
term: negative regulation of type III interferon production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034346
term: positive regulation of type III interferon production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034347
term: type III interferon binding
ontology: MF
definition:
Interacting selectively and non-covalently with a type III interferon. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034348
term: type III interferon receptor activity
ontology: MF
definition:
Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far.


go_id: GO:0034351
term: negative regulation of glial cell apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.


go_id: GO:0034352
term: positive regulation of glial cell apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.


go_id: GO:0034353
term: RNA pyrophosphohydrolase activity
ontology: MF
definition:
Catalysis of the removal of a 5' terminal pyrophosphate from the 5'-triphosphate end of an RNA, leaving a 5'-monophosphate end.


go_id: GO:0034354
term: 'de novo' NAD biosynthetic process from tryptophan
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


go_id: GO:0034355
term: NAD salvage
ontology: BP
definition:
Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam).


go_id: GO:0034356
term: NAD biosynthesis via nicotinamide riboside salvage pathway
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside.


go_id: GO:0034357
term: photosynthetic membrane
ontology: CC
definition:
A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place.


go_id: GO:0034358
term: plasma lipoprotein particle
ontology: CC
definition:
A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.


go_id: GO:0034359
term: mature chylomicron
ontology: CC
definition:
A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph.


go_id: GO:0034360
term: chylomicron remnant
ontology: CC
definition:
A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver.


go_id: GO:0034361
term: very-low-density lipoprotein particle
ontology: CC
definition:
A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.


go_id: GO:0034362
term: low-density lipoprotein particle
ontology: CC
definition:
A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver.


go_id: GO:0034363
term: intermediate-density lipoprotein particle
ontology: CC
definition:
A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL).


go_id: GO:0034364
term: high-density lipoprotein particle
ontology: CC
definition:
A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.


go_id: GO:0034365
term: discoidal high-density lipoprotein particle
ontology: CC
definition:
A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase).


go_id: GO:0034366
term: spherical high-density lipoprotein particle
ontology: CC
definition:
A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).


go_id: GO:0034369
term: plasma lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).


go_id: GO:0034370
term: triglyceride-rich lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle.


go_id: GO:0034371
term: chylomicron remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.


go_id: GO:0034372
term: very-low-density lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.


go_id: GO:0034373
term: intermediate-density lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle.


go_id: GO:0034374
term: low-density lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.


go_id: GO:0034375
term: high-density lipoprotein particle remodeling
ontology: BP
definition:
The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.


go_id: GO:0034376
ontology: BP
term:
conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle

definition:
The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle.


go_id: GO:0034379
term: very-low-density lipoprotein particle assembly
ontology: BP
definition:
The aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle.


go_id: GO:0034381
term: plasma lipoprotein particle clearance
ontology: BP
definition:
The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


go_id: GO:0034382
term: chylomicron remnant clearance
ontology: BP
definition:
The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.


go_id: GO:0034383
term: low-density lipoprotein particle clearance
ontology: BP
definition:
The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


go_id: GO:0034384
term: high-density lipoprotein particle clearance
ontology: BP
definition:
The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


go_id: GO:0034385
term: triglyceride-rich lipoprotein particle
ontology: CC
definition:
A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoproteinparticles transport lipids, which are non-covalently associated with the particles, in the blood.


go_id: GO:0034386
term: 4-aminobutyrate:2-oxoglutarate transaminase activity
ontology: MF
definition:
Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.


go_id: GO:0034388
term: Pwp2p-containing subcomplex of 90S preribosome
ontology: CC
definition:
A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p.


go_id: GO:0034389
term: lipid particle organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.


go_id: GO:0034390
term: smooth muscle cell apoptotic process
ontology: BP
definition:
Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.


go_id: GO:0034392
term: negative regulation of smooth muscle cell apoptotic process
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.


go_id: GO:0034393
term: positive regulation of smooth muscle cell apoptotic process
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.


go_id: GO:0034394
term: protein localization to cell surface
ontology: BP
definition:
A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.


go_id: GO:0034395
term: regulation of transcription from RNA polymerase II promoter in response to iron
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus.


go_id: GO:0034396
term: negative regulation of transcription from RNA polymerase II promoter in response to iron
ontology: BP
definition:
Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.


go_id: GO:0034400
term: gerontoplast
ontology: CC
definition:
A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence.


go_id: GO:0034401
term: chromatin organization involved in regulation of transcription
ontology: BP
definition:
Any cellular process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin that modulates the rate, frequency or extent of DNA-dependent transcription.


go_id: GO:0034402
term: recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
ontology: BP
definition:
The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript.


go_id: GO:0034403
term: alignment of 3' and 5' splice sites of mRNA
ontology: BP
definition:
Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur.


go_id: GO:0034404
term: nucleobase-containing small molecule biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.


go_id: GO:0034405
term: response to fluid shear stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.


go_id: GO:0034406
term: cell wall beta-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0034407
term: cell wall (1->3)-beta-D-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0034408
term: ascospore wall beta-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0034409
term: ascospore wall (1->3)-beta-D-glucan metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0034410
term: cell wall beta-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0034411
term: cell wall (1->3)-beta-D-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.


go_id: GO:0034412
term: ascospore wall beta-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0034413
term: ascospore wall (1->3)-beta-D-glucan biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.


go_id: GO:0034414
term: tRNA 3'-trailer cleavage, endonucleolytic
ontology: BP
definition:
Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.


go_id: GO:0034415
term: tRNA 3'-trailer cleavage, exonucleolytic
ontology: BP
definition:
Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.


go_id: GO:0034418
term: urate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine.


go_id: GO:0034420
term: co-translational protein acetylation
ontology: BP
definition:
The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome.


go_id: GO:0034421
term: post-translational protein acetylation
ontology: BP
definition:
The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome.


go_id: GO:0034424
term: Vps55/Vps68 complex
ontology: CC
definition:
A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins.


go_id: GO:0034425
term: etioplast envelope
ontology: CC
definition:
The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.


go_id: GO:0034427
term: nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.


go_id: GO:0034428
term: nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.


go_id: GO:0034429
term: tectobulbar tract morphogenesis
ontology: BP
definition:
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.


go_id: GO:0034431
term: bis(5'-adenosyl)-hexaphosphatase activity
ontology: MF
definition:
Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate.


go_id: GO:0034432
term: bis(5'-adenosyl)-pentaphosphatase activity
ontology: MF
definition:
Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate.


go_id: GO:0034433
term: steroid esterification
ontology: BP
definition:
A lipid modification process in which a steroid ester is formed by the combination of a carboxylic acid (often a fatty acid) and a steroid molecule (e.g. cholesterol).


go_id: GO:0034434
term: sterol esterification
ontology: BP
definition:
A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and a sterol molecule (e.g. cholesterol).


go_id: GO:0034435
term: cholesterol esterification
ontology: BP
definition:
A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.


go_id: GO:0034436
term: glycoprotein transport
ontology: BP
definition:
The directed movement of a glycoprotein, any protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034437
term: glycoprotein transporter activity
ontology: MF
definition:
Enables the directed movement of a glycoprotein, any protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells.


go_id: GO:0034440
term: lipid oxidation
ontology: BP
definition:
The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.


go_id: GO:0034441
term: plasma lipoprotein particle oxidation
ontology: BP
definition:
The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group, occurring in the blood plasma.


go_id: GO:0034443
term: negative regulation of lipoprotein oxidation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation.


go_id: GO:0034444
term: regulation of plasma lipoprotein particle oxidation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma.


go_id: GO:0034445
term: negative regulation of plasma lipoprotein particle oxidation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma.


go_id: GO:0034446
term: substrate adhesion-dependent cell spreading
ontology: BP
definition:
The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.


go_id: GO:0034447
term: very-low-density lipoprotein particle clearance
ontology: BP
definition:
The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


go_id: GO:0034448
term: EGO complex
ontology: CC
definition:
A vacuolar membrane-associated protein complex that is required for activation of microautophagy during exit from rapamycin-induced growth arrest. In budding yeast, S. cerevisiae, this complex includes Gtr1p, Gtr2p, Meh1p, and Slm4p.


go_id: GO:0034450
term: ubiquitin-ubiquitin ligase activity
ontology: MF
definition:
Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.


go_id: GO:0034451
term: centriolar satellite
ontology: CC
definition:
A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.


go_id: GO:0034452
term: dynactin binding
ontology: MF
definition:
Interacting selectively and non-covalently with any part of a dynactin complex; dynactin is a large protein complex that activates dynein-based motor activity.


go_id: GO:0034454
term: microtubule anchoring at centrosome
ontology: BP
definition:
Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome.


go_id: GO:0034455
term: t-UTP complex
ontology: CC
definition:
A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p.


go_id: GO:0034456
term: UTP-C complex
ontology: CC
definition:
A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p.


go_id: GO:0034457
term: Mpp10 complex
ontology: CC
definition:
A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p.


go_id: GO:0034459
term: ATP-dependent 3'-5' RNA helicase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 3' to 5'.


go_id: GO:0034461
term: uropod retraction
ontology: BP
definition:
The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell.


go_id: GO:0034462
term: small-subunit processome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome.


go_id: GO:0034463
term: 90S preribosome assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions.


go_id: GO:0034464
term: BBSome
ontology: CC
definition:
A protein complex that associates with the primary cilium and is involved in cilium biogenesis; consists of seven conserved proteins: BBS1, BBS2, BBS4, BBS5, BBS7, BBS8 and BBS9.


go_id: GO:0034465
term: response to carbon monoxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.


go_id: GO:0034469
term: Golgi stack lumen
ontology: CC
definition:
The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex.


go_id: GO:0034470
term: ncRNA processing
ontology: BP
definition:
Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules.


go_id: GO:0034478
term: phosphatidylglycerol catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.


go_id: GO:0034479
term: phosphatidylglycerol phospholipase C activity
ontology: MF
definition:
Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate.


go_id: GO:0034481
term: chondroitin sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate.


go_id: GO:0034482
term: chondroitin 2-O-sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues.


go_id: GO:0034483
term: heparan sulfate sulfotransferase activity
ontology: MF
definition:
Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate.


go_id: GO:0034484
term: raffinose catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.


go_id: GO:0034485
term: phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-3,4-bisphosphate + phosphate.


go_id: GO:0034487
term: vacuolar amino acid transmembrane transport
ontology: BP
definition:
The process in which an amino acid is transported from one side of the vacuolar membrane to the other.


go_id: GO:0034497
term: protein localization to pre-autophagosomal structure
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, the pre-autophagosomal structure (PAS).


go_id: GO:0034502
term: protein localization to chromosome
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.


go_id: GO:0034503
term: protein localization to nucleolar rDNA repeats
ontology: BP
definition:
Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus.


go_id: GO:0034505
term: tooth mineralization
ontology: BP
definition:
The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum.


go_id: GO:0034506
term: chromosome, centromeric core domain
ontology: CC
definition:
The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it.


go_id: GO:0034507
term: chromosome, centromeric outer repeat region
ontology: CC
definition:
The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it.


go_id: GO:0034508
term: centromere complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.


go_id: GO:0034510
term: centromere separation
ontology: BP
definition:
The cell cycle process in which centromeres are physically detached from each other during chromosome separation.


go_id: GO:0034514
term: mitochondrial unfolded protein response
ontology: BP
definition:
The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.


go_id: GO:0034515
term: proteasome storage granule
ontology: CC
definition:
A multisubunit proteasome complex that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state.


go_id: GO:0034516
term: response to vitamin B6
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.


go_id: GO:0034518
term: RNA cap binding complex
ontology: CC
definition:
Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA.


go_id: GO:0034519
term: cytoplasmic RNA cap binding complex
ontology: CC
definition:
A protein complex found in the cytoplasm that binds the 5' cap structure of an mRNA, and typically consists of the cap-binding protein eIF4E, the adaptor protein eIF4G, and a multi-factor complex comprising eIF1, eIF2, eIF3 and eIF5. This complex mediates recruitment of the 40S subunit to mRNA.


go_id: GO:0034521
term: 1-naphthoic acid dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+.


go_id: GO:0034522
term: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-.


go_id: GO:0034523
term: 3-formylsalicylate oxidase activity
ontology: MF
definition:
Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide.


go_id: GO:0034526
term: 2-methylnaphthalene hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O.


go_id: GO:0034527
term: 1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene.


go_id: GO:0034528
term: 2-carboxy-2-hydroxy-8-carboxychromene isomerase activity
ontology: MF
definition:
Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate.


go_id: GO:0034529
term: 2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate.


go_id: GO:0034530
term: 4-hydroxymethylsalicyaldehyde dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+.


go_id: GO:0034531
term: 2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde.


go_id: GO:0034532
term: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate.


go_id: GO:0034533
term: 1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate.


go_id: GO:0034534
term: 1-methylnaphthalene hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O.


go_id: GO:0034535
term: 1,2-dihydroxy-8-methylnaphthalene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+.


go_id: GO:0034536
term: 2-hydroxy-8-methylchromene-2-carboxylate isomerase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate.


go_id: GO:0034537
term: 2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde.


go_id: GO:0034539
term: 3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr.


go_id: GO:0034544
term: trans-ACOHDA hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3.


go_id: GO:0034551
term: mitochondrial respiratory chain complex III assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane.


go_id: GO:0034552
term: respiratory chain complex II assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II.


go_id: GO:0034553
term: mitochondrial respiratory chain complex II assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane.


go_id: GO:0034554
term: 3,3',5-tribromobisphenol A reductive dehalogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr.


go_id: GO:0034559
term: bisphenol A hydroxylase B activity
ontology: MF
definition:
Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O.


go_id: GO:0034560
term: bisphenol A hydroxylase A activity
ontology: MF
definition:
Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O.


go_id: GO:0034561
term: 1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O.


go_id: GO:0034562
term: 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O.


go_id: GO:0034563
term: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-.


go_id: GO:0034564
term: 4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-.


go_id: GO:0034565
term: 1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol.


go_id: GO:0034568
term: isoproturon dimethylaminedehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-.


go_id: GO:0034569
term: monodemethylisoproturon dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-.


go_id: GO:0034570
term: hydroxymonomethylisoproturon dimethylaminedehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.


go_id: GO:0034571
term: 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid.


go_id: GO:0034572
term: monodemethylisoproturon dimethylaminedehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-.


go_id: GO:0034574
term: didemethylisoproturon dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.


go_id: GO:0034575
term: 4-isopropylaniline dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-.


go_id: GO:0034582
term: 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034583
term: 21U-RNA binding
ontology: MF
definition:
Interacting selectively and non-covalently with a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.


go_id: GO:0034584
term: piRNA binding
ontology: MF
definition:
Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.


go_id: GO:0034585
term: 21U-RNA metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.


go_id: GO:0034586
term: 21U-RNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.


go_id: GO:0034587
term: piRNA metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.


go_id: GO:0034588
term: piRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.


go_id: GO:0034589
term: hydroxyproline transport
ontology: BP
definition:
The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034597
term: phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
ontology: MF
definition:
Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.


go_id: GO:0034598
term: phosphothreonine lyase activity
ontology: MF
definition:
Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product.


go_id: GO:0034599
term: cellular response to oxidative stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.


go_id: GO:0034605
term: cellular response to heat
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.


go_id: GO:0034606
term: response to hermaphrodite contact
ontology: BP
definition:
The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate.


go_id: GO:0034607
term: turning behavior involved in mating
ontology: BP
definition:
The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.


go_id: GO:0034608
term: vulval location
ontology: BP
definition:
Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.


go_id: GO:0034609
term: spicule insertion
ontology: BP
definition:
Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.


go_id: GO:0034610
term: oligodeoxyribonucleotidase activity
ontology: MF
definition:
Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates.


go_id: GO:0034611
term: oligoribonucleotidase activity
ontology: MF
definition:
Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates.


go_id: GO:0034612
term: response to tumor necrosis factor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.


go_id: GO:0034613
term: cellular protein localization
ontology: BP
definition:
Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.


go_id: GO:0034614
term: cellular response to reactive oxygen species
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.


go_id: GO:0034615
term: GCH1 complex
ontology: CC
definition:
A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive.


go_id: GO:0034616
term: response to laminar fluid shear stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls.


go_id: GO:0034617
term: tetrahydrobiopterin binding
ontology: MF
definition:
Interacting selectively and non-covalently with a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions.


go_id: GO:0034620
term: cellular response to unfolded protein
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.


go_id: GO:0034622
term: cellular macromolecular complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of macromolecules to form a complex, carried out at the cellular level.


go_id: GO:0034624
term: DNA recombinase assembly involved in gene conversion at mating-type locus
ontology: BP
definition:
The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another.


go_id: GO:0034627
term: 'de novo' NAD biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


go_id: GO:0034628
term: 'de novo' NAD biosynthetic process from aspartate
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.


go_id: GO:0034629
term: cellular protein complex localization
ontology: BP
definition:
A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell.


go_id: GO:0034631
term: microtubule anchoring at spindle pole body
ontology: BP
definition:
Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end.


go_id: GO:0034632
term: retinol transporter activity
ontology: MF
definition:
Enables the directed movement of retinol into, out of or within a cell, or between cells. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.


go_id: GO:0034633
term: retinol transport
ontology: BP
definition:
The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.


go_id: GO:0034634
term: glutathione transmembrane transporter activity
ontology: MF
definition:
Enables the directed movement of glutathione, the tripeptide glutamylcysteinylglycine, across a membrane into, out of or within a cell, or between cells.


go_id: GO:0034635
term: glutathione transport
ontology: BP
definition:
The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034636
term: strand invasion involved in gene conversion at mating-type locus
ontology: BP
definition:
The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA at the mating-type locus. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This process occurs as part of gene conversion at the mating-type locus.


go_id: GO:0034637
term: cellular carbohydrate biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells.


go_id: GO:0034638
term: phosphatidylcholine catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.


go_id: GO:0034639
term: L-amino acid efflux transmembrane transporter activity
ontology: MF
definition:
Catalysis of the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane.


go_id: GO:0034640
term: establishment of mitochondrion localization by microtubule attachment
ontology: BP
definition:
The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.


go_id: GO:0034641
term: cellular nitrogen compound metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.


go_id: GO:0034643
term: establishment of mitochondrion localization, microtubule-mediated
ontology: BP
definition:
The directed movement of the mitochondrion to a specific location, by a process involving microtubules.


go_id: GO:0034644
term: cellular response to UV
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.


go_id: GO:0034645
term: cellular macromolecule biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.


go_id: GO:0034647
term: histone demethylase activity (H3-trimethyl-K4 specific)
ontology: MF
definition:
Catalysis of the removal of a methyl group from trimethylated lysine at position 4 of the histone H3 protein.


go_id: GO:0034648
term: histone demethylase activity (H3-dimethyl-K4 specific)
ontology: MF
definition:
Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein.


go_id: GO:0034649
term: histone demethylase activity (H3-monomethyl-K4 specific)
ontology: MF
definition:
Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 4) + O2 + FAD + H2O = histone H3 L-lysine (position 4) + H2O2 + formaldehyde + FADH2. This reaction is the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein.


go_id: GO:0034650
term: cortisol metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.


go_id: GO:0034651
term: cortisol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.


go_id: GO:0034652
term: extrachromosomal circular DNA localization involved in cell aging
ontology: BP
definition:
A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging.


go_id: GO:0034653
term: retinoic acid catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.


go_id: GO:0034654
term: nucleobase-containing compound biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.


go_id: GO:0034655
term: nucleobase-containing compound catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.


go_id: GO:0034656
term: nucleobase-containing small molecule catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.


go_id: GO:0034657
term: GID complex
ontology: CC
definition:
A protein complex with ubiquitin ligase activity that is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. In S. cerevisiae, the GID (Glucose Induced degradation Deficient) complex consists of Vid30p, Rmd5p, Vid24p, Vid28p, Gid7p, Gid8p, and Fyv10p.


go_id: GO:0034659
term: isopropylmalate transport
ontology: BP
definition:
The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034661
term: ncRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs).


go_id: GO:0034662
term: CFTR-NHERF-ezrin complex
ontology: CC
definition:
A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.


go_id: GO:0034663
term: endoplasmic reticulum chaperone complex
ontology: CC
definition:
A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.


go_id: GO:0034664
term: Ig heavy chain-bound endoplasmic reticulum chaperone complex
ontology: CC
definition:
A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.


go_id: GO:0034671
ontology: BP
term:
retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification

definition:
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros.


go_id: GO:0034672
term: anterior/posterior pattern specification involved in pronephros development
ontology: BP
definition:
The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.


go_id: GO:0034673
term: inhibin-betaglycan-ActRII complex
ontology: CC
definition:
A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B.


go_id: GO:0034692
term: E.F.G complex
ontology: CC
definition:
A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex.


go_id: GO:0034693
term: U11/U12 snRNP
ontology: CC
definition:
A ribonucleoprotein complex formed by the association of the U11 and U12 small nuclear ribonucleoproteins.


go_id: GO:0034694
term: response to prostaglandin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.


go_id: GO:0034695
term: response to prostaglandin E
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.


go_id: GO:0034696
term: response to prostaglandin F
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.


go_id: GO:0034697
term: response to prostaglandin I
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.


go_id: GO:0034698
term: response to gonadotropin
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.


go_id: GO:0034699
term: response to luteinizing hormone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.


go_id: GO:0034702
term: ion channel complex
ontology: CC
definition:
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.


go_id: GO:0034709
term: methylosome
ontology: CC
definition:
A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains.


go_id: GO:0034710
term: inhibin complex binding
ontology: MF
definition:
Interacting selectively and non-covalently with an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit.


go_id: GO:0034711
term: inhibin binding
ontology: MF
definition:
Interacting selectively and non-covalently with an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.


go_id: GO:0034714
term: type III transforming growth factor beta receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a type III transforming growth factor beta receptor.


go_id: GO:0034715
term: pICln-Sm protein complex
ontology: CC
definition:
A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG.


go_id: GO:0034716
term: Gemin3-Gemin4-Gemin5 complex
ontology: CC
definition:
A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly.


go_id: GO:0034717
term: Gemin6-Gemin7-unrip complex
ontology: CC
definition:
A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly.


go_id: GO:0034718
term: SMN-Gemin2 complex
ontology: CC
definition:
A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex.


go_id: GO:0034719
term: SMN-Sm protein complex
ontology: CC
definition:
A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.


go_id: GO:0034720
term: histone H3-K4 demethylation
ontology: BP
definition:
The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone.


go_id: GO:0034721
term: histone H3-K4 demethylation, trimethyl-H3-K4-specific
ontology: BP
definition:
The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone.


go_id: GO:0034723
term: DNA replication-dependent nucleosome organization
ontology: BP
definition:
The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation.


go_id: GO:0034724
term: DNA replication-independent nucleosome organization
ontology: BP
definition:
The formation or destruction of chromatin structures, occurring outside the context of DNA replication.


go_id: GO:0034729
term: histone H3-K79 methylation
ontology: BP
definition:
The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone.


go_id: GO:0034730
term: SmD-containing SMN-Sm protein complex
ontology: CC
definition:
An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex.


go_id: GO:0034731
term: Lsm-containing SMN-Sm protein complex
ontology: CC
definition:
An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA.


go_id: GO:0034732
term: transcription factor TFIIIB-alpha complex
ontology: CC
definition:
A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters.


go_id: GO:0034733
term: transcription factor TFIIIB-beta complex
ontology: CC
definition:
A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters.


go_id: GO:0034734
term: transcription factor TFIIIC1 complex
ontology: CC
definition:
A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity.


go_id: GO:0034735
term: transcription factor TFIIIC2 complex
ontology: CC
definition:
A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter.


go_id: GO:0034739
term: histone deacetylase activity (H4-K16 specific)
ontology: MF
definition:
Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.


go_id: GO:0034740
term: TFIIIC-TOP1-SUB1 complex
ontology: CC
definition:
A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III.


go_id: GO:0034741
term: APC-tubulin-IQGAP1 complex
ontology: CC
definition:
A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization.


go_id: GO:0034743
term: APC-IQGAP complex
ontology: CC
definition:
A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.


go_id: GO:0034744
term: APC-IQGAP1-Cdc42 complex
ontology: CC
definition:
A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.


go_id: GO:0034745
term: APC-IQGAP1-Rac1 complex
ontology: CC
definition:
A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.


go_id: GO:0034746
term: APC-IQGAP1-CLIP-170 complex
ontology: CC
definition:
A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration.


go_id: GO:0034748
term: Par3-APC-KIF3A complex
ontology: CC
definition:
A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity.


go_id: GO:0034749
term: Scrib-APC complex
ontology: CC
definition:
A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation.


go_id: GO:0034750
term: Scrib-APC-beta-catenin complex
ontology: CC
definition:
A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation.


go_id: GO:0034751
term: aryl hydrocarbon receptor complex
ontology: CC
definition:
A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR.


go_id: GO:0034752
term: cytosolic aryl hydrocarbon receptor complex
ontology: CC
definition:
An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP.


go_id: GO:0034753
term: nuclear aryl hydrocarbon receptor complex
ontology: CC
definition:
An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT).


go_id: GO:0034754
term: cellular hormone metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells.


go_id: GO:0034755
term: iron ion transmembrane transport
ontology: BP
definition:
A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034756
term: regulation of iron ion transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034757
term: negative regulation of iron ion transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034758
term: positive regulation of iron ion transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0034759
term: regulation of iron ion transmembrane transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034760
term: negative regulation of iron ion transmembrane transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034761
term: positive regulation of iron ion transmembrane transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034762
term: regulation of transmembrane transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.


go_id: GO:0034763
term: negative regulation of transmembrane transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.


go_id: GO:0034764
term: positive regulation of transmembrane transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.


go_id: GO:0034765
term: regulation of ion transmembrane transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.


go_id: GO:0034766
term: negative regulation of ion transmembrane transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.


go_id: GO:0034767
term: positive regulation of ion transmembrane transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.


go_id: GO:0034769
term: basement membrane disassembly
ontology: BP
definition:
The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.


go_id: GO:0034770
term: histone H4-K20 methylation
ontology: BP
definition:
The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone.


go_id: GO:0034771
term: histone H4-K20 monomethylation
ontology: BP
definition:
The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone.


go_id: GO:0034772
term: histone H4-K20 dimethylation
ontology: BP
definition:
The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone.


go_id: GO:0034773
term: histone H4-K20 trimethylation
ontology: BP
definition:
The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone.


go_id: GO:0034775
term: glutathione transmembrane transport
ontology: BP
definition:
A process in which glutathione is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0034776
term: response to histamine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.


go_id: GO:0034778
term: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034779
term: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA.


go_id: GO:0034787
term: 1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-.


go_id: GO:0034788
term: 2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+.


go_id: GO:0034789
term: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+.


go_id: GO:0034790
term: 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-.


go_id: GO:0034797
term: fosfomycin 2-glutathione ligase activity
ontology: MF
definition:
Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid.


go_id: GO:0034798
term: fosfomycin 2-L-cysteine ligase activity
ontology: MF
definition:
Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid.


go_id: GO:0034799
term: dihydride TNP tautomerase activity
ontology: MF
definition:
Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form).


go_id: GO:0034800
term: trinitrophenol dihydride denitratase activity
ontology: MF
definition:
Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP.


go_id: GO:0034802
term: branched-chain dodecylbenzene sulfonate monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite.


go_id: GO:0034803
term: 3-hydroxy-2-naphthoate 2,3-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate.


go_id: GO:0034805
term: benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-.


go_id: GO:0034812
term: 9,10-dihydroxybenzo(a)pyrene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate.


go_id: GO:0034814
term: 7,8-dihydroxy benzo(a)pyrene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate.


go_id: GO:0034815
term: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity
ontology: MF
definition:
Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+.


go_id: GO:0034818
term: ADD 9alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin.


go_id: GO:0034819
term: 3-HSA hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O.


go_id: GO:0034820
term: 4,9-DSHA hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+.


go_id: GO:0034825
term: tetralin ring-hydroxylating dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+.


go_id: GO:0034826
term: 1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+.


go_id: GO:0034827
term: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+.


go_id: GO:0034828
term: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+.


go_id: GO:0034829
term: 2-hydroxydec-2,4-diene-1,10-dioate hydratase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate.


go_id: GO:0034831
term: (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-.


go_id: GO:0034834
term: 2-mercaptobenzothiazole dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol.


go_id: GO:0034836
term: 6-hydroxy-2-mercaptobenzothiazole monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole.


go_id: GO:0034837
term: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-.


go_id: GO:0034842
term: thiophene-2-carboxylate-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi.


go_id: GO:0034844
term: naphthyl-2-methyl-succinate CoA-transferase activity
ontology: MF
definition:
Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate.


go_id: GO:0034845
term: naphthyl-2-methyl-succinyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034846
term: naphthyl-2-methylene-succinyl-CoA lyase activity
ontology: MF
definition:
Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA.


go_id: GO:0034847
term: naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034848
term: naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity
ontology: MF
definition:
Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA.


go_id: GO:0034851
term: 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA.


go_id: GO:0034852
term: 4,4-dimethyl-3-oxopentanal dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-.


go_id: GO:0034855
term: 4-AD 9alpha-hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O.


go_id: GO:0034860
term: 2-mercaptobenzothiazole desulfurase activity
ontology: MF
definition:
Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor.


go_id: GO:0034866
term: 2,4,4-trimethylpentanoyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034867
term: 2,4,4-trimethylpent-2-enoyl-CoA hydratase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA.


go_id: GO:0034868
term: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034869
term: 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH.


go_id: GO:0034871
term: 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-.


go_id: GO:0034874
term: thioacetamide S-oxide S-oxygenase activity
ontology: MF
definition:
Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O.


go_id: GO:0034877
term: isonicotinate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor.


go_id: GO:0034878
term: 2-hydroxyisonicotinate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor.


go_id: GO:0034893
term: N-nitrodimethylamine hydroxylase activity
ontology: MF
definition:
Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O.


go_id: GO:0034897
term: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol.


go_id: GO:0034898
term: hexadecyltrimethylammonium chloride monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O.


go_id: GO:0034899
term: trimethylamine monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O.


go_id: GO:0034906
term: N-isopropylaniline 1,2-dixoxygenase activity
ontology: MF
definition:
Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine.


go_id: GO:0034908
term: 2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+.


go_id: GO:0034909
term: 6-hydroxypseudooxynicotine dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine.


go_id: GO:0034910
term: 6-hydroxy-3-succinoylpyridine hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine.


go_id: GO:0034912
term: phthalate 3,4-cis-dihydrodiol dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+.


go_id: GO:0034914
term: trinitrophenol hydride denitratase activity
ontology: MF
definition:
Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP.


go_id: GO:0034918
term: 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-.


go_id: GO:0034924
term: cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2.


go_id: GO:0034934
term: phenanthrene-4-carboxylate dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate.


go_id: GO:0034935
term: tetrachlorobenzene dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+.


go_id: GO:0034936
term: 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity
ontology: MF
definition:
Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+.


go_id: GO:0034938
term: pyrrole-2-carboxylate monooxygenase activity
ontology: MF
definition:
Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O.


go_id: GO:0034942
term: cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.


go_id: GO:0034943
term: trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
ontology: MF
definition:
Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.


go_id: GO:0034944
term: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+.


go_id: GO:0034945
term: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA.


go_id: GO:0034948
term: 2,6-dihydroxypseudooxynicotine hydrolase activity
ontology: MF
definition:
Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate.


go_id: GO:0034959
term: endothelin maturation
ontology: BP
definition:
The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin.


go_id: GO:0034963
term: box C/D snoRNA processing
ontology: BP
definition:
Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript into a mature box C/D snoRNA.


go_id: GO:0034964
term: box H/ACA snoRNA processing
ontology: BP
definition:
Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript into a mature box H/ACA snoRNA.


go_id: GO:0034965
term: intronic box C/D snoRNA processing
ontology: BP
definition:
Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA.


go_id: GO:0034966
term: intronic box H/ACA snoRNA processing
ontology: BP
definition:
Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA.


go_id: GO:0034967
term: Set3 complex
ontology: CC
definition:
A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p.


go_id: GO:0034970
term: histone H3-R2 methylation
ontology: BP
definition:
The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone.


go_id: GO:0034971
term: histone H3-R17 methylation
ontology: BP
definition:
The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.


go_id: GO:0034972
term: histone H3-R26 methylation
ontology: BP
definition:
The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone.


go_id: GO:0034973
term: Sid2-Mob1 complex
ontology: CC
definition:
A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex.


go_id: GO:0034974
term: Swi5-Swi2 complex
ontology: CC
definition:
A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching.


go_id: GO:0034975
term: protein folding in endoplasmic reticulum
ontology: BP
definition:
A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).


go_id: GO:0034976
term: response to endoplasmic reticulum stress
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.


go_id: GO:0034977
term: ABIN2-NFKB1-MAP3K8 complex
ontology: CC
definition:
A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages.


go_id: GO:0034978
term: PDX1-PBX1b-MRG1 complex
ontology: CC
definition:
A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes.


go_id: GO:0034985
term: Ecsit-NDUFAF1 complex
ontology: CC
definition:
Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed.


go_id: GO:0034987
term: immunoglobulin receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with one or more specific sites on an immunoglobulin receptor molecule.


go_id: GO:0034988
term: Fc-gamma receptor I complex binding
ontology: MF
definition:
Interacting selectively and non-covalently with one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.


go_id: GO:0034990
term: nuclear mitotic cohesin complex
ontology: CC
definition:
A cohesin complex that mediates sister chromatid cohesion in the nucleus during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.


go_id: GO:0034991
term: nuclear meiotic cohesin complex
ontology: CC
definition:
A cohesin complex that mediates sister chromatid cohesion in the nucleus during meiosis; has a subunit composition distinct from that of the meiotic cohesin complex.


go_id: GO:0034992
term: microtubule organizing center attachment site
ontology: CC
definition:
A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope.


go_id: GO:0034993
term: LINC complex
ontology: CC
definition:
A protein complex that spans the nuclear outer and inner membranes, thereby linking the major cytoplasmic cytoskeleton elements to the nuclear lumen; the complex is conserved in eukaryotes and contains proteins with SUN and KASH domains.


go_id: GO:0034994
term: microtubule organizing center attachment site organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches.


go_id: GO:0034995
term: SC5b-7 complex
ontology: CC
definition:
A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly.


go_id: GO:0034996
term: RasGAP-Fyn-Lyn-Yes complex
ontology: CC
definition:
A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation.


go_id: GO:0034997
term: alphav-beta5 integrin-vitronectin complex
ontology: CC
definition:
A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin.


go_id: GO:0034998
term: oligosaccharyltransferase I complex
ontology: CC
definition:
An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes.


go_id: GO:0034999
term: oligosaccharyltransferase II complex
ontology: CC
definition:
An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes.


go_id: GO:0035000
term: oligosaccharyltransferase III complex
ontology: CC
definition:
An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes.


go_id: GO:0035001
term: dorsal trunk growth, open tracheal system
ontology: BP
definition:
Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system.


go_id: GO:0035002
term: liquid clearance, open tracheal system
ontology: BP
definition:
The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.


go_id: GO:0035003
term: subapical complex
ontology: CC
definition:
The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.


go_id: GO:0035004
term: phosphatidylinositol 3-kinase activity
ontology: MF
definition:
Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring.


go_id: GO:0035006
term: melanization defense response
ontology: BP
definition:
The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.


go_id: GO:0035007
term: regulation of melanization defense response
ontology: BP
definition:
Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.


go_id: GO:0035008
term: positive regulation of melanization defense response
ontology: BP
definition:
Any process that increases the rate or extent of the melanization defense response during injury or invasion.


go_id: GO:0035009
term: negative regulation of melanization defense response
ontology: BP
definition:
Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.


go_id: GO:0035010
term: encapsulation of foreign target
ontology: BP
definition:
Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization.


go_id: GO:0035014
term: phosphatidylinositol 3-kinase regulator activity
ontology: MF
definition:
Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.


go_id: GO:0035015
term: elongation of arista core
ontology: BP
definition:
The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.


go_id: GO:0035016
term: elongation of arista lateral
ontology: BP
definition:
The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.


go_id: GO:0035018
term: adult chitin-based cuticle pattern formation
ontology: BP
definition:
The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster.


go_id: GO:0035019
term: somatic stem cell population maintenance
ontology: BP
definition:
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.


go_id: GO:0035021
term: negative regulation of Rac protein signal transduction
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction.


go_id: GO:0035022
term: positive regulation of Rac protein signal transduction
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.


go_id: GO:0035024
term: negative regulation of Rho protein signal transduction
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.


go_id: GO:0035025
term: positive regulation of Rho protein signal transduction
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.


go_id: GO:0035026
term: leading edge cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet.


go_id: GO:0035027
term: leading edge cell fate commitment
ontology: BP
definition:
The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet.


go_id: GO:0035028
term: leading edge cell fate determination
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.


go_id: GO:0035029
term: dorsal closure, leading edge cell fate commitment
ontology: BP
definition:
The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis.


go_id: GO:0035032
term: phosphatidylinositol 3-kinase complex, class III
ontology: CC
definition:
A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).


go_id: GO:0035036
term: sperm-egg recognition
ontology: BP
definition:
The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.


go_id: GO:0035037
term: sperm entry
ontology: BP
definition:
An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur.


go_id: GO:0035039
term: male pronucleus assembly
ontology: BP
definition:
The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division.


go_id: GO:0035042
term: fertilization, exchange of chromosomal proteins
ontology: BP
definition:
Replacement of sperm-specific chromosomal proteins with somatic histones, to allow the paternal genome to acquire a nucleosomal chromatin organization compatible with nuclear activity.


go_id: GO:0035043
term: male pronuclear envelope synthesis
ontology: BP
definition:
Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation.


go_id: GO:0035044
term: sperm aster formation
ontology: BP
definition:
Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei.


go_id: GO:0035045
term: sperm plasma membrane disassembly
ontology: BP
definition:
The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.


go_id: GO:0035047
term: centrosomal and pronuclear rotation
ontology: BP
definition:
The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion.


go_id: GO:0035048
term: splicing factor protein import into nucleus
ontology: BP
definition:
The directed movement of a pre-mRNA splicing factor from the cytoplasm into the nucleus, across the nuclear membrane.


go_id: GO:0035050
term: embryonic heart tube development
ontology: BP
definition:
The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.


go_id: GO:0035051
term: cardiocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.


go_id: GO:0035052
term: dorsal vessel aortic cell fate commitment
ontology: BP
definition:
The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035053
term: dorsal vessel heart proper cell fate commitment
ontology: BP
definition:
The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035054
term: embryonic heart tube anterior/posterior pattern specification
ontology: BP
definition:
The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.


go_id: GO:0035058
term: nonmotile primary cilium assembly
ontology: BP
definition:
The assembly of a primary cilium which contains a variable array of axonemal microtubules but does not contain molecular motors. Nonmotile primary cilia are found on many different cell types and function as sensory organelles that concentrate and organize sensory signaling molecules.


go_id: GO:0035059
term: RCAF complex
ontology: CC
definition:
A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4.


go_id: GO:0035060
term: brahma complex
ontology: CC
definition:
A SWI/SNF-type complex that contains the ATPase product of the Drosophila brahma gene, or an ortholog thereof.


go_id: GO:0035061
term: interchromatin granule
ontology: CC
definition:
A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).


go_id: GO:0035062
term: omega speckle
ontology: CC
definition:
A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs).


go_id: GO:0035063
term: nuclear speck organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.


go_id: GO:0035064
term: methylated histone binding
ontology: MF
definition:
Interacting selectively and non-covalently with a histone protein in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.


go_id: GO:0035065
term: regulation of histone acetylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein.


go_id: GO:0035066
term: positive regulation of histone acetylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein.


go_id: GO:0035067
term: negative regulation of histone acetylation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein.


go_id: GO:0035068
term: micro-ribonucleoprotein complex
ontology: CC
definition:
A complex containing both protein and micro-RNA (miRNA) molecules. miRNAs are approximately 22 nucleotide noncoding RNAs derived from endogenous genes; they are processed from the stem of a longer hairpin like structure termed a pre-miRNA.


go_id: GO:0035069
term: larval midgut histolysis
ontology: BP
definition:
The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.


go_id: GO:0035070
term: salivary gland histolysis
ontology: BP
definition:
The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.


go_id: GO:0035072
term: ecdysone-mediated induction of salivary gland cell autophagic cell death
ontology: BP
definition:
Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis.


go_id: GO:0035073
term: pupariation
ontology: BP
definition:
The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis.


go_id: GO:0035074
term: pupation
ontology: BP
definition:
The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period.


go_id: GO:0035075
term: response to ecdysone
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.


go_id: GO:0035077
term: ecdysone-mediated polytene chromosome puffing
ontology: BP
definition:
The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation.


go_id: GO:0035078
term: induction of programmed cell death by ecdysone
ontology: BP
definition:
Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death.


go_id: GO:0035079
term: polytene chromosome puffing
ontology: BP
definition:
The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals.


go_id: GO:0035080
term: heat shock-mediated polytene chromosome puffing
ontology: BP
definition:
The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.


go_id: GO:0035081
term: induction of programmed cell death by hormones
ontology: BP
definition:
Any process induced by hormones that directly activates any of the steps required for programmed cell death.


go_id: GO:0035082
term: axoneme assembly
ontology: BP
definition:
The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.


go_id: GO:0035087
term: siRNA loading onto RISC involved in RNA interference
ontology: BP
definition:
The transfer of small interfering RNA molecules (siRNAs) from the Dicer family of enzymes that cleave the double-stranded RNA, onto the nuclease-containing RNA-initiated silencing complex (RISC), in the context of RNA interference.


go_id: GO:0035088
term: establishment or maintenance of apical/basal cell polarity
ontology: BP
definition:
Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.


go_id: GO:0035091
term: phosphatidylinositol binding
ontology: MF
definition:
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.


go_id: GO:0035092
term: sperm chromatin condensation
ontology: BP
definition:
The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.


go_id: GO:0035093
term: spermatogenesis, exchange of chromosomal proteins
ontology: BP
definition:
The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin.


go_id: GO:0035094
term: response to nicotine
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.


go_id: GO:0035095
term: behavioral response to nicotine
ontology: BP
definition:
Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.


go_id: GO:0035096
term: larval midgut cell programmed cell death
ontology: BP
definition:
The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ.


go_id: GO:0035098
term: ESC/E(Z) complex
ontology: CC
definition:
A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.


go_id: GO:0035099
term: hemocyte migration
ontology: BP
definition:
The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.


go_id: GO:0035100
term: ecdysone binding
ontology: MF
definition:
Interacting selectively and non-covalently with 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.


go_id: GO:0035101
term: FACT complex
ontology: CC
definition:
An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer.


go_id: GO:0035102
term: PRC1 complex
ontology: CC
definition:
A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.


go_id: GO:0035103
term: sterol regulatory element binding protein cleavage
ontology: BP
definition:
The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids.


go_id: GO:0035105
term: sterol regulatory element binding protein import into nucleus
ontology: BP
definition:
The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes.


go_id: GO:0035106
term: operant conditioning
ontology: BP
definition:
Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.


go_id: GO:0035107
term: appendage morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.


go_id: GO:0035108
term: limb morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.


go_id: GO:0035114
term: imaginal disc-derived appendage morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism.


go_id: GO:0036023
term: embryonic skeletal limb joint morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb.


go_id: GO:0035112
term: genitalia morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.


go_id: GO:0035113
term: embryonic appendage morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.


go_id: GO:0035115
term: embryonic forelimb morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.


go_id: GO:0035116
term: embryonic hindlimb morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.


go_id: GO:0035118
term: embryonic pectoral fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.


go_id: GO:0035119
term: embryonic pelvic fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


go_id: GO:0035120
term: post-embryonic appendage morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.


go_id: GO:0036342
term: post-anal tail morphogenesis
ontology: BP
definition:
The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.


go_id: GO:0048809
term: analia morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster.


go_id: GO:0035122
term: embryonic medial fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.


go_id: GO:0035123
term: embryonic dorsal fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.


go_id: GO:0035124
term: embryonic caudal fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.


go_id: GO:0035125
term: embryonic anal fin morphogenesis
ontology: BP
definition:
The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


go_id: GO:0035126
term: post-embryonic genitalia morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.


go_id: GO:0035127
term: post-embryonic limb morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.


go_id: GO:0035128
term: post-embryonic forelimb morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism.


go_id: GO:0035129
term: post-embryonic hindlimb morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized.


go_id: GO:0035130
term: post-embryonic pectoral fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.


go_id: GO:0035131
term: post-embryonic pelvic fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


go_id: GO:0035132
term: post-embryonic medial fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.


go_id: GO:0035133
term: post-embryonic caudal fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.


go_id: GO:0035134
term: post-embryonic dorsal fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.


go_id: GO:0035135
term: post-embryonic anal fin morphogenesis
ontology: BP
definition:
The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


go_id: GO:0035136
term: forelimb morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.


go_id: GO:0035138
term: pectoral fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.


go_id: GO:0035139
term: pelvic fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


go_id: GO:0035141
term: medial fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.


go_id: GO:0035142
term: dorsal fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.


go_id: GO:0035143
term: caudal fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.


go_id: GO:0035144
term: anal fin morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


go_id: GO:0035145
term: exon-exon junction complex
ontology: CC
definition:
A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.


go_id: GO:0035147
term: branch fusion, open tracheal system
ontology: BP
definition:
Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.


go_id: GO:0035148
term: tube formation
ontology: BP
definition:
Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.


go_id: GO:0035150
term: regulation of tube size
ontology: BP
definition:
Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes.


go_id: GO:0035151
term: regulation of tube size, open tracheal system
ontology: BP
definition:
Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.


go_id: GO:0035152
term: regulation of tube architecture, open tracheal system
ontology: BP
definition:
Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network.


go_id: GO:0035153
term: epithelial cell type specification, open tracheal system
ontology: BP
definition:
Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.


go_id: GO:0035154
term: terminal cell fate specification, open tracheal system
ontology: BP
definition:
The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange.


go_id: GO:0035155
term: negative regulation of terminal cell fate specification, open tracheal system
ontology: BP
definition:
Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.


go_id: GO:0035156
term: fusion cell fate specification
ontology: BP
definition:
The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion.


go_id: GO:0035157
term: negative regulation of fusion cell fate specification
ontology: BP
definition:
Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.


go_id: GO:0035158
term: regulation of tube diameter, open tracheal system
ontology: BP
definition:
Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size.


go_id: GO:0035160
term: maintenance of epithelial integrity, open tracheal system
ontology: BP
definition:
Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process.


go_id: GO:0035161
term: imaginal disc lineage restriction
ontology: BP
definition:
Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment.


go_id: GO:0035163
term: embryonic hemocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.


go_id: GO:0035164
term: embryonic plasmatocyte differentiation
ontology: BP
definition:
The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.


go_id: GO:0035165
term: embryonic crystal cell differentiation
ontology: BP
definition:
The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.


go_id: GO:0035167
term: larval lymph gland hemopoiesis
ontology: BP
definition:
The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.


go_id: GO:0035168
term: larval lymph gland hemocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035169
term: lymph gland plasmatocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.


go_id: GO:0035170
term: lymph gland crystal cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.


go_id: GO:0035171
term: lamellocyte differentiation
ontology: BP
definition:
The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


go_id: GO:0035172
term: hemocyte proliferation
ontology: BP
definition:
The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.


go_id: GO:0035173
term: histone kinase activity
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.


go_id: GO:0035174
term: histone serine kinase activity
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.


go_id: GO:0035175
term: histone kinase activity (H3-S10 specific)
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3.


go_id: GO:0035176
term: social behavior
ontology: BP
definition:
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.


go_id: GO:0035178
term: turning behavior
ontology: BP
definition:
Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source.


go_id: GO:0035179
term: larval turning behavior
ontology: BP
definition:
Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source.


go_id: GO:0035180
term: larval wandering behavior
ontology: BP
definition:
The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction.


go_id: GO:0035181
term: larval burrowing behavior
ontology: BP
definition:
Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation.


go_id: GO:0035182
term: female germline ring canal outer rim
ontology: CC
definition:
An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues.


go_id: GO:0035183
term: female germline ring canal inner rim
ontology: CC
definition:
A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins.


go_id: GO:0035184
term: histone threonine kinase activity
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.


go_id: GO:0035185
term: preblastoderm mitotic cell cycle
ontology: BP
definition:
The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis.


go_id: GO:0035186
term: syncytial blastoderm mitotic cell cycle
ontology: BP
definition:
Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively.


go_id: GO:0035187
term: hatching behavior
ontology: BP
definition:
The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.


go_id: GO:0035189
term: Rb-E2F complex
ontology: CC
definition:
A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression.


go_id: GO:0035190
term: syncytial nuclear migration
ontology: BP
definition:
The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex.


go_id: GO:0035191
term: nuclear axial expansion
ontology: BP
definition:
The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex.


go_id: GO:0035192
term: nuclear cortical migration
ontology: BP
definition:
The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo.


go_id: GO:0035193
term: larval central nervous system remodeling
ontology: BP
definition:
Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035194
term: posttranscriptional gene silencing by RNA
ontology: BP
definition:
Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger mRNA degradation or negatively regulate translation.


go_id: GO:0035195
term: gene silencing by miRNA
ontology: BP
definition:
Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of mRNA cleavage or translational repression, usually accompanied by poly-A tail shortgening and subsequent degredation of the mRNA.


go_id: GO:0035197
term: siRNA binding
ontology: MF
definition:
Interacting selectively and non-covalently with a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme.


go_id: GO:0035198
term: miRNA binding
ontology: MF
definition:
Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.


go_id: GO:0035200
term: leg disc anterior/posterior pattern formation
ontology: BP
definition:
The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc.


go_id: GO:0035201
term: leg disc anterior/posterior lineage restriction
ontology: BP
definition:
Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment.


go_id: GO:0035202
term: tracheal pit formation in open tracheal system
ontology: BP
definition:
Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster.


go_id: GO:0035203
term: regulation of lamellocyte differentiation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


go_id: GO:0035204
term: negative regulation of lamellocyte differentiation
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


go_id: GO:0035205
term: positive regulation of lamellocyte differentiation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


go_id: GO:0035206
term: regulation of hemocyte proliferation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.


go_id: GO:0035207
term: negative regulation of hemocyte proliferation
ontology: BP
definition:
Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.


go_id: GO:0035208
term: positive regulation of hemocyte proliferation
ontology: BP
definition:
Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.


go_id: GO:0035209
term: pupal development
ontology: BP
definition:
The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.


go_id: GO:0035210
term: prepupal development
ontology: BP
definition:
The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation.


go_id: GO:0035211
term: spermathecum morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk.


go_id: GO:0035212
term: cell competition in a multicellular organism
ontology: BP
definition:
Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.


go_id: GO:0035213
term: clypeo-labral disc development
ontology: BP
definition:
The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite.


go_id: GO:0035214
term: eye-antennal disc development
ontology: BP
definition:
Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.


go_id: GO:0035215
term: genital disc development
ontology: BP
definition:
Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia.


go_id: GO:0035216
term: haltere disc development
ontology: BP
definition:
Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.


go_id: GO:0035217
term: labial disc development
ontology: BP
definition:
Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis.


go_id: GO:0035218
term: leg disc development
ontology: BP
definition:
Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.


go_id: GO:0035219
term: prothoracic disc development
ontology: BP
definition:
Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle.


go_id: GO:0035220
term: wing disc development
ontology: BP
definition:
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.


go_id: GO:0035221
term: genital disc pattern formation
ontology: BP
definition:
The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc.


go_id: GO:0035224
term: genital disc anterior/posterior pattern formation
ontology: BP
definition:
The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium).


go_id: GO:0035225
term: determination of genital disc primordium
ontology: BP
definition:
Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two.


go_id: GO:0035229
term: positive regulation of glutamate-cysteine ligase activity
ontology: BP
definition:
Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate.


go_id: GO:0035230
term: cytoneme
ontology: CC
definition:
A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um.


go_id: GO:0035231
term: cytoneme assembly
ontology: BP
definition:
Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.


go_id: GO:0035232
term: germ cell attraction
ontology: BP
definition:
The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target.


go_id: GO:0035233
term: germ cell repulsion
ontology: BP
definition:
The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue.


go_id: GO:0035234
term: ectopic germ cell programmed cell death
ontology: BP
definition:
Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.


go_id: GO:0035235
term: ionotropic glutamate receptor signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035238
term: vitamin A biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids.


go_id: GO:0035239
term: tube morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.


go_id: GO:0035240
term: dopamine binding
ontology: MF
definition:
Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.


go_id: GO:0035241
term: protein-arginine omega-N monomethyltransferase activity
ontology: MF
definition:
Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue.


go_id: GO:0035242
term: protein-arginine omega-N asymmetric methyltransferase activity
ontology: MF
definition:
Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues.


go_id: GO:0035243
term: protein-arginine omega-N symmetric methyltransferase activity
ontology: MF
definition:
Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.


go_id: GO:0035247
term: peptidyl-arginine omega-N-methylation
ontology: BP
definition:
The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein.


go_id: GO:0035248
term: alpha-1,4-N-acetylgalactosaminyltransferase activity
ontology: MF
definition:
Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage.


go_id: GO:0035249
term: synaptic transmission, glutamatergic
ontology: BP
definition:
The process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.


go_id: GO:0035253
term: ciliary rootlet
ontology: CC
definition:
A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.


go_id: GO:0035255
term: ionotropic glutamate receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels.


go_id: GO:0035256
term: G-protein coupled glutamate receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a G-protein coupled glutamate receptor (a metabotropic glutamate receptor).


go_id: GO:0035257
term: nuclear hormone receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell.


go_id: GO:0035260
term: internal genitalia morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.


go_id: GO:0035261
term: external genitalia morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals.


go_id: GO:0035262
term: gonad morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.


go_id: GO:0035263
term: genital disc sexually dimorphic development
ontology: BP
definition:
The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed.


go_id: GO:0035265
term: organ growth
ontology: BP
definition:
The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.


go_id: GO:0035266
term: meristem growth
ontology: BP
definition:
The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.


go_id: GO:0035267
term: NuA4 histone acetyltransferase complex
ontology: CC
definition:
A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).


go_id: GO:0035269
term: protein O-linked mannosylation
ontology: BP
definition:
The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage.


go_id: GO:0035270
term: endocrine system development
ontology: BP
definition:
Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.


go_id: GO:0035271
term: ring gland development
ontology: BP
definition:
Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones.


go_id: GO:0035272
term: exocrine system development
ontology: BP
definition:
Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.


go_id: GO:0035277
term: spiracle morphogenesis, open tracheal system
ontology: BP
definition:
The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk.


go_id: GO:0035278
term: negative regulation of translation involved in gene silencing by miRNA
ontology: BP
definition:
The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.


go_id: GO:0035279
term: mRNA cleavage involved in gene silencing by miRNA
ontology: BP
definition:
The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.


go_id: GO:0035280
term: miRNA loading onto RISC involved in gene silencing by miRNA
ontology: BP
definition:
The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing complex (RISC).


go_id: GO:0035281
term: pre-miRNA export from nucleus
ontology: BP
definition:
Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product.


go_id: GO:0035282
term: segmentation
ontology: BP
definition:
The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.


go_id: GO:0035285
term: appendage segmentation
ontology: BP
definition:
Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.


go_id: GO:0036011
term: imaginal disc-derived leg segmentation
ontology: BP
definition:
Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint.


go_id: GO:0035287
term: head segmentation
ontology: BP
definition:
Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial).


go_id: GO:0035288
term: anterior head segmentation
ontology: BP
definition:
Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments.


go_id: GO:0035289
term: posterior head segmentation
ontology: BP
definition:
Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains.


go_id: GO:0035290
term: trunk segmentation
ontology: BP
definition:
Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8.


go_id: GO:0035291
term: specification of segmental identity, intercalary segment
ontology: BP
definition:
The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


go_id: GO:0035292
term: specification of segmental identity, trunk
ontology: BP
definition:
The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


go_id: GO:0035293
term: chitin-based larval cuticle pattern formation
ontology: BP
definition:
The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.


go_id: GO:0035294
term: determination of wing disc primordium
ontology: BP
definition:
Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc.


go_id: GO:0035295
term: tube development
ontology: BP
definition:
The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.


go_id: GO:0035297
term: regulation of Malpighian tubule diameter
ontology: BP
definition:
Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells.


go_id: GO:0035299
term: inositol pentakisphosphate 2-kinase activity
ontology: MF
definition:
Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+).


go_id: GO:0052725
term: inositol-1,3,4-trisphosphate 6-kinase activity
ontology: MF
definition:
Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+).


go_id: GO:0052726
term: inositol-1,3,4-trisphosphate 5-kinase activity
ontology: MF
definition:
Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+).


go_id: GO:0035301
term: Hedgehog signaling complex
ontology: CC
definition:
A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila).


go_id: GO:0035302
term: ecdysteroid 25-hydroxylase activity
ontology: MF
definition:
Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods.


go_id: GO:0035303
term: regulation of dephosphorylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.


go_id: GO:0035304
term: regulation of protein dephosphorylation
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein.


go_id: GO:0035305
term: negative regulation of dephosphorylation
ontology: BP
definition:
Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.


go_id: GO:0035306
term: positive regulation of dephosphorylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.


go_id: GO:0035307
term: positive regulation of protein dephosphorylation
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.


go_id: GO:0035308
term: negative regulation of protein dephosphorylation
ontology: BP
definition:
Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein.


go_id: GO:0035309
term: wing and notum subfield formation
ontology: BP
definition:
The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures.


go_id: GO:0035310
term: notum cell fate specification
ontology: BP
definition:
The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.


go_id: GO:0035311
term: wing cell fate specification
ontology: BP
definition:
The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment.


go_id: GO:0035313
term: wound healing, spreading of epidermal cells
ontology: BP
definition:
The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis.


go_id: GO:0035314
term: scab formation
ontology: BP
definition:
Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.


go_id: GO:0035316
term: non-sensory hair organization
ontology: BP
definition:
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis.


go_id: GO:0035317
term: imaginal disc-derived wing hair organization
ontology: BP
definition:
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.


go_id: GO:0035318
term: imaginal disc-derived wing hair outgrowth
ontology: BP
definition:
Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair.


go_id: GO:0035319
term: imaginal disc-derived wing hair elongation
ontology: BP
definition:
Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.


go_id: GO:0035320
term: imaginal disc-derived wing hair site selection
ontology: BP
definition:
Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally.


go_id: GO:0035321
term: maintenance of imaginal disc-derived wing hair orientation
ontology: BP
definition:
Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity.


go_id: GO:0035322
term: mesenchymal cell migration involved in limb bud formation
ontology: BP
definition:
The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud.


go_id: GO:0035325
term: Toll-like receptor binding
ontology: MF
definition:
Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response.


go_id: GO:0035326
term: enhancer binding
ontology: MF
definition:
Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.


go_id: GO:0035327
term: transcriptionally active chromatin
ontology: CC
definition:
The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.


go_id: GO:0035328
term: transcriptionally silent chromatin
ontology: CC
definition:
The ordered and organized complex of DNA and protein that forms regions of the chromosome that are not being actively transcribed.


go_id: GO:0035329
term: hippo signaling
ontology: BP
definition:
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.


go_id: GO:0035333
term: Notch receptor processing, ligand-dependent
ontology: BP
definition:
The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD).


go_id: GO:0035334
term: Notch receptor processing, ligand-independent
ontology: BP
definition:
The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.


go_id: GO:0035336
term: long-chain fatty-acyl-CoA metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.


go_id: GO:0035337
term: fatty-acyl-CoA metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.


go_id: GO:0035338
term: long-chain fatty-acyl-CoA biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.


go_id: GO:0035339
term: SPOTS complex
ontology: CC
definition:
A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis.


go_id: GO:0035340
term: inosine transport
ontology: BP
definition:
The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035341
term: regulation of inosine transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035342
term: positive regulation of inosine transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035343
term: negative regulation of inosine transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035344
term: hypoxanthine transport
ontology: BP
definition:
The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035345
term: regulation of hypoxanthine transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035346
term: positive regulation of hypoxanthine transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035347
term: negative regulation of hypoxanthine transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035348
term: acetyl-CoA transmembrane transport
ontology: BP
definition:
The process in which acetyl-CoA is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.


go_id: GO:0035349
term: coenzyme A transmembrane transport
ontology: BP
definition:
The process in which coenzyme A is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.


go_id: GO:0035350
term: FAD transmembrane transport
ontology: BP
definition:
The process in which flavin-adenine dinucleotide (FAD) is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.


go_id: GO:0035351
term: heme transmembrane transport
ontology: BP
definition:
The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0035352
term: NAD transmembrane transport
ontology: BP
definition:
The process in which nicotinamide adenine dinucleotide is transported from one side of a membrane to the other by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH.


go_id: GO:0035353
term: nicotinamide mononucleotide transmembrane transport
ontology: BP
definition:
The process in which nicotinamide mononucleotide is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.


go_id: GO:0035354
term: Toll-like receptor 1-Toll-like receptor 2 protein complex
ontology: CC
definition:
A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2).


go_id: GO:0035355
term: Toll-like receptor 2-Toll-like receptor 6 protein complex
ontology: CC
definition:
A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6).


go_id: GO:0035356
term: cellular triglyceride homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment.


go_id: GO:0035357
term: peroxisome proliferator activated receptor signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes.


go_id: GO:0035358
term: regulation of peroxisome proliferator activated receptor signaling pathway
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


go_id: GO:0035359
term: negative regulation of peroxisome proliferator activated receptor signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


go_id: GO:0035360
term: positive regulation of peroxisome proliferator activated receptor signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.


go_id: GO:0035361
term: Cul8-RING ubiquitin ligase complex
ontology: CC
definition:
A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins.


go_id: GO:0035362
term: protein-DNA ISRE complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA.


go_id: GO:0035363
term: histone locus body
ontology: CC
definition:
A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body.


go_id: GO:0035364
term: thymine transport
ontology: BP
definition:
The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035365
term: regulation of thymine transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035366
term: negative regulation of thymine transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035367
term: positive regulation of thymine transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


go_id: GO:0035368
term: selenocysteine insertion sequence binding
ontology: MF
definition:
Interacting selectively and non-covalently with the selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.


go_id: GO:0035369
term: pre-B cell receptor complex
ontology: CC
definition:
An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


go_id: GO:0035370
term: UBC13-UEV1A complex
ontology: CC
definition:
A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A).


go_id: GO:0035371
term: microtubule plus-end
ontology: CC
definition:
The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.


go_id: GO:0035373
term: chondroitin sulfate proteoglycan binding
ontology: MF
definition:
Interacting selectively and non-covalently with a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.


go_id: GO:0035374
term: chondroitin sulfate binding
ontology: MF
definition:
Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).


go_id: GO:0035375
term: zymogen binding
ontology: MF
definition:
Interacting selectively and non-covalently with a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.


go_id: GO:0035376
term: sterol import
ontology: BP
definition:
The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


go_id: GO:0035378
term: carbon dioxide transmembrane transport
ontology: BP
definition:
A process in which carbon dioxide (CO2) is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0035380
term: very long-chain-3-hydroxyacyl-CoA dehydrogenase activity
ontology: MF
definition:
Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.


go_id: GO:0035381
term: ATP-gated ion channel activity
ontology: MF
definition:
Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.


go_id: GO:0035382
term: sterol transmembrane transport
ontology: BP
definition:
The directed movement of a sterol across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


go_id: GO:0035383
term: thioester metabolic process
ontology: BP
definition:
The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.


go_id: GO:0035384
term: thioester biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.


go_id: GO:0035385
term: Roundabout signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035387
term: negative regulation of Roundabout signaling pathway
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway.


go_id: GO:0035388
term: positive regulation of Roundabout signaling pathway
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway.


go_id: GO:0035389
term: establishment of chromatin silencing at silent mating-type cassette
ontology: BP
definition:
The initial formation of a transcriptionally silent chromatin structure such as heterochromatin at silent mating-type loci.


go_id: GO:0035390
term: establishment of chromatin silencing at telomere
ontology: BP
definition:
The initial formation of a transcriptionally silent chromatin structure such as heterochromatin at the telomere.


go_id: GO:0035391
term: maintenance of chromatin silencing at silent mating-type cassette
ontology: BP
definition:
The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at silent mating-type loci.


go_id: GO:0035392
term: maintenance of chromatin silencing at telomere
ontology: BP
definition:
The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at the telomere.


go_id: GO:0035393
term: chemokine (C-X-C motif) ligand 9 production
ontology: BP
definition:
The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0035394
term: regulation of chemokine (C-X-C motif) ligand 9 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


go_id: GO:0035395
term: negative regulation of chemokine (C-X-C motif) ligand 9 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


go_id: GO:0035396
term: positive regulation of chemokine (C-X-C motif) ligand 9 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


go_id: GO:0035397
term: helper T cell enhancement of adaptive immune response
ontology: BP
definition:
Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.


go_id: GO:0035398
term: helper T cell enhancement of T cell mediated immune response
ontology: BP
definition:
Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.


go_id: GO:0035399
term: helper T cell enhancement of B cell mediated immune response
ontology: BP
definition:
Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.


go_id: GO:0035400
term: histone tyrosine kinase activity
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to a tyrosine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.


go_id: GO:0035401
term: histone kinase activity (H3-Y41 specific)
ontology: MF
definition:
The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone.


go_id: GO:0035402
term: histone kinase activity (H3-T11 specific)
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3.


go_id: GO:0035403
term: histone kinase activity (H3-T6 specific)
ontology: MF
definition:
Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3.


go_id: GO:0035407
term: histone H3-T11 phosphorylation
ontology: BP
definition:
The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone.


go_id: GO:0035408
term: histone H3-T6 phosphorylation
ontology: BP
definition:
The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone.


go_id: GO:0035412
term: regulation of catenin import into nucleus
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.


go_id: GO:0035413
term: positive regulation of catenin import into nucleus
ontology: BP
definition:
Any process that increases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.


go_id: GO:0035414
term: negative regulation of catenin import into nucleus
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.


go_id: GO:0035418
term: protein localization to synapse
ontology: BP
definition:
Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.


go_id: GO:0035419
term: activation of MAPK activity involved in innate immune response
ontology: BP
definition:
Any process that initiates the activity of the inactive enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035420
term: MAPK cascade involved in innate immune response
ontology: BP
definition:
A MAPK cascade that contributes to an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035421
term: activation of MAPKK activity involved in innate immune response
ontology: BP
definition:
Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035422
term: activation of MAPKKK activity involved in innate immune response
ontology: BP
definition:
Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035423
term: inactivation of MAPK activity involved in innate immune response
ontology: BP
definition:
Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035424
term: MAPK import into nucleus involved in innate immune response
ontology: BP
definition:
The directed movement of a MAP kinase to the nucleus in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.


go_id: GO:0035425
term: autocrine signaling
ontology: BP
definition:
Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type.


go_id: GO:0035428
term: hexose transmembrane transport
ontology: BP
definition:
The directed movement of hexose across a membrane by means of some agent such as a transporter or pore. Hexoses are any aldoses with a chain of six carbon atoms in the molecule.


go_id: GO:0035429
term: gluconate transmembrane transport
ontology: BP
definition:
The directed movement of gluconate across a membrane by means of some agent such as a transporter or pore. Gluconate is the aldonic acid derived from glucose.


go_id: GO:0035430
term: regulation of gluconate transmembrane transport
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.


go_id: GO:0035431
term: negative regulation of gluconate transmembrane transport
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.


go_id: GO:0035432
term: positive regulation of gluconate transmembrane transport
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.


go_id: GO:0035433
term: acetate transmembrane transport
ontology: BP
definition:
The directed movement of acetate across a membrane by means of some agent such as a transporter or pore. Acetate is the 2-carbon carboxylic acid ethanoic acid.


go_id: GO:0035435
term: phosphate ion transmembrane transport
ontology: BP
definition:
The directed movement of phosphate across a membrane by means of some agent such as a transporter or pore.


go_id: GO:0035436
term: triose phosphate transmembrane transport
ontology: BP
definition:
The directed movement of triose phosphate across a membrane by means of some agent such as a transporter or pore. Triose phosphate is any organic three carbon compound phosphate ester.


go_id: GO:0035437
term: maintenance of protein localization in endoplasmic reticulum
ontology: BP
definition:
Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum.


go_id: GO:0035438
term: cyclic-di-GMP binding
ontology: MF
definition:
Interacting selectively and non-covalently with cyclic-di-GMP, cyclic dimeric guanosine monophosphate.


go_id: GO:0035440
term: tuberculosinol biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria.


go_id: GO:0035441
term: cell migration involved in vasculogenesis
ontology: BP
definition:
The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes.


go_id: GO:0035442
term: dipeptide transmembrane transport
ontology: BP
definition:
The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.


go_id: GO:0035443
term: tripeptide transmembrane transport
ontology: BP
definition:
The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds.


go_id: GO:0035444
term: nickel cation transmembrane transport
ontology: BP
definition:
The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore.


go_id: GO:0035445
term: borate transmembrane transport
ontology: BP
definition:
The directed movement of borate across a membrane by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.


go_id: GO:0035446
term: cysteine-glucosaminylinositol ligase activity
ontology: MF
definition:
Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.


go_id: GO:0035447
term: mycothiol synthase activity
ontology: MF
definition:
Catalysis of the reaction: 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coenzyme A + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol.


go_id: GO:0035448
term: extrinsic component of thylakoid membrane
ontology: CC
definition:
The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


go_id: GO:0035449
term: extrinsic component of plastid thylakoid membrane
ontology: CC
definition:
The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


go_id: GO:0035450
term: extrinsic component of lumenal side of plastid thylakoid membrane
ontology: CC
definition:
The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region.


go_id: GO:0035451
term: extrinsic component of stromal side of plastid thylakoid membrane
ontology: CC
definition:
The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.


go_id: GO:0035452
term: extrinsic component of plastid membrane
ontology: CC
definition:
The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


go_id: GO:0035453
term: extrinsic component of plastid inner membrane
ontology: CC
definition:
The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


go_id: GO:0035454
term: extrinsic component of stromal side of plastid inner membrane
ontology: CC
definition:
The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.


go_id: GO:0035455
term: response to interferon-alpha
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.


go_id: GO:0035456
term: response to interferon-beta
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.


go_id: GO:0035457
term: cellular response to interferon-alpha
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.


go_id: GO:0035458
term: cellular response to interferon-beta
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.


go_id: GO:0035459
term: cargo loading into vesicle
ontology: BP
definition:
The formation of a protein complex between the coat proteins and proteins that are going to be transported by a vesicle.


go_id: GO:0035461
term: vitamin transmembrane transport
ontology: BP
definition:
The process in which a vitamin is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.


go_id: GO:0035463
ontology: BP
term:
transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry

definition:
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to determination of organismal asymmetry with respect to the left and right halves.


go_id: GO:0035464
ontology: BP
term:
regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry

definition:
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of organismal asymmetry with regard to its left and right halves.


go_id: GO:1900175
ontology: BP
term:
regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry

definition:
Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm.


go_id: GO:0035469
term: determination of pancreatic left/right asymmetry
ontology: BP
definition:
Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism.


go_id: GO:0035470
term: positive regulation of vascular wound healing
ontology: BP
definition:
Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.


go_id: GO:0035471
term: luteinizing hormone signaling pathway involved in ovarian follicle development
ontology: BP
definition:
The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure.


go_id: GO:0035474
term: selective angioblast sprouting
ontology: BP
definition:
The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel.


go_id: GO:0035475
term: angioblast cell migration involved in selective angioblast sprouting
ontology: BP
definition:
The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations.


go_id: GO:0035477
term: regulation of angioblast cell migration involved in selective angioblast sprouting
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting.


go_id: GO:0035478
term: chylomicron binding
ontology: MF
definition:
Interacting selectively and non-covalently with a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE.


go_id: GO:0035479
term: angioblast cell migration from lateral mesoderm to midline
ontology: BP
definition:
The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature.


go_id: GO:0035480
term: regulation of Notch signaling pathway involved in heart induction
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.


go_id: GO:0035481
term: positive regulation of Notch signaling pathway involved in heart induction
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.


go_id: GO:0035482
term: gastric motility
ontology: BP
definition:
The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum.


go_id: GO:0035483
term: gastric emptying
ontology: BP
definition:
The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.


go_id: GO:0035490
term: regulation of leukotriene production involved in inflammatory response
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.


go_id: GO:0035491
term: positive regulation of leukotriene production involved in inflammatory response
ontology: BP
definition:
Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.


go_id: GO:0035492
term: negative regulation of leukotriene production involved in inflammatory response
ontology: BP
definition:
Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.


go_id: GO:0035493
term: SNARE complex assembly
ontology: BP
definition:
The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


go_id: GO:0035494
term: SNARE complex disassembly
ontology: BP
definition:
The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


go_id: GO:0035495
term: regulation of SNARE complex disassembly
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


go_id: GO:0035496
term: lipopolysaccharide-1,5-galactosyltransferase activity
ontology: MF
definition:
Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide.


go_id: GO:0035497
term: cAMP response element binding
ontology: MF
definition:
Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP.


go_id: GO:0035499
term: carnosine biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine).


go_id: GO:0035500
term: MH2 domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.


go_id: GO:0035501
term: MH1 domain binding
ontology: MF
definition:
Interacting selectively and non-covalently with the MH1 (MAD homology 1) domain of a protein. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors.


go_id: GO:0035502
term: metanephric part of ureteric bud development
ontology: BP
definition:
The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros.


go_id: GO:0035503
term: ureter part of ureteric bud development
ontology: BP
definition:
The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter.


go_id: GO:0035505
term: positive regulation of myosin light chain kinase activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity.


go_id: GO:0035506
term: negative regulation of myosin light chain kinase activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity.


go_id: GO:0035507
term: regulation of myosin-light-chain-phosphatase activity
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity.


go_id: GO:0035508
term: positive regulation of myosin-light-chain-phosphatase activity
ontology: BP
definition:
Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity.


go_id: GO:0035509
term: negative regulation of myosin-light-chain-phosphatase activity
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity.


go_id: GO:0035511
term: oxidative DNA demethylation
ontology: BP
definition:
Removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.


go_id: GO:0035513
term: oxidative RNA demethylation
ontology: BP
definition:
The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms.


go_id: GO:0035515
term: oxidative RNA demethylase activity
ontology: MF
definition:
Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.


go_id: GO:0035516
term: oxidative DNA demethylase activity
ontology: MF
definition:
Catalysis of the removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.


go_id: GO:0035517
term: PR-DUB complex
ontology: CC
definition:
A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively.


go_id: GO:0035519
term: protein K29-linked ubiquitination
ontology: BP
definition:
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation.


go_id: GO:0035523
term: protein K29-linked deubiquitination
ontology: BP
definition:
A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein.


go_id: GO:0035524
term: proline transmembrane transport
ontology: BP
definition:
The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore.


go_id: GO:0035526
term: retrograde transport, plasma membrane to Golgi
ontology: BP
definition:
The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles.


go_id: GO:0035528
term: UDP-N-acetylglucosamine biosynthesis involved in chitin biosynthesis
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine in glycosidic linkage with uridine diphosphate, that contribute to the biosynthesis of chitin.


go_id: GO:0035530
term: chemokine (C-C motif) ligand 6 production
ontology: BP
definition:
The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0035531
term: regulation of chemokine (C-C motif) ligand 6 production
ontology: BP
definition:
Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


go_id: GO:0035532
term: negative regulation of chemokine (C-C motif) ligand 6 production
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


go_id: GO:0035533
term: positive regulation of chemokine (C-C motif) ligand 6 production
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


go_id: GO:0035535
term: regulation of chemokine (C-C motif) ligand 6 secretion
ontology: BP
definition:
Any process that modulates the rate, frequency or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell.


go_id: GO:0035536
term: negative regulation of chemokine (C-C motif) ligand 6 secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell.


go_id: GO:0035537
term: positive regulation of chemokine (C-C motif) ligand 6 secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell.


go_id: GO:0035538
term: carbohydrate response element binding
ontology: MF
definition:
Interacting selectively and non-covalently with the carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes.


go_id: GO:0035539
term: 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
ontology: MF
definition:
Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate + diphosphate. 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate, or 8-oxo-dGTP, is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA.


go_id: GO:0035540
term: positive regulation of SNARE complex disassembly
ontology: BP
definition:
Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


go_id: GO:0035541
term: negative regulation of SNARE complex disassembly
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


go_id: GO:0035542
term: regulation of SNARE complex assembly
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


go_id: GO:0035543
term: positive regulation of SNARE complex assembly
ontology: BP
definition:
Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


go_id: GO:0035544
term: negative regulation of SNARE complex assembly
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


go_id: GO:0035548
term: negative regulation of interferon-beta secretion
ontology: BP
definition:
Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta secretion.


go_id: GO:0035549
term: positive regulation of interferon-beta secretion
ontology: BP
definition:
Any process that activates or increases the frequency, rate, or extent of interferon-beta secretion.


go_id: GO:0035550
term: urease complex
ontology: CC
definition:
A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide).


go_id: GO:0035551
term: protein initiator methionine removal involved in protein maturation
ontology: BP
definition:
Removal of the initiating methionine or formylmethionine residue from a protein that contributes to protein maturation, the attainment of the full functional capacity of a protein.


go_id: GO:0035552
term: oxidative single-stranded DNA demethylation
ontology: BP
definition:
Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.


go_id: GO:0035553
term: oxidative single-stranded RNA demethylation
ontology: BP
definition:
Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.


go_id: GO:0035554
term: termination of Roundabout signal transduction
ontology: BP
definition:
The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated.


go_id: GO:0048495
term: Roundabout binding
ontology: MF
definition:
Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor.


go_id: GO:0038028
term: insulin receptor signaling pathway via phosphatidylinositol 3-kinase
ontology: BP
definition:
The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade.


go_id: GO:0038029
term: epidermal growth factor receptor signaling pathway via MAPK cascade
ontology: BP
definition:
The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on via the MAPKKK cascade.


go_id: GO:0035560
term: pheophoridase activity
ontology: MF
definition:
Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a.


go_id: GO:0035561
term: regulation of chromatin binding
ontology: BP
definition:
Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.


go_id: GO:0035562
term: negative regulation of chromatin binding
ontology: BP
definition:
Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.


go_id: GO:0035563
term: positive regulation of chromatin binding
ontology: BP
definition:
Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.


go_id: GO:0035567
term: non-canonical Wnt signaling pathway
ontology: BP
definition:
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin.


go_id: GO:0035573
term: N-terminal peptidyl-serine trimethylation
ontology: BP
definition:
The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.


go_id: GO:0035574
term: histone H4-K20 demethylation
ontology: BP
definition:
The modification of histone H4 by the removal of a methyl group from lysine at position 20 of the histone.


go_id: GO:0035575
term: histone demethylase activity (H4-K20 specific)
ontology: MF
definition:
Catalysis of the reaction: histone H4 N6-methyl-L-lysine (position 20) + 2-oxoglutarate + O2 = histone H4 L-lysine (position 20) + succinate + formaldehyde + CO2. This reaction is the removal of a methyl group from lysine at position 20 of the histone H4 protein.


go_id: GO:0035576
term: retinoic acid receptor signaling pathway involved in pronephric field specification
ontology: BP
definition:
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop.


go_id: GO:0035577
term: azurophil granule membrane
ontology: CC
definition:
The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.


go_id: GO:0035578
term: azurophil granule lumen
ontology: CC
definition:
The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.


go_id: GO:0035579
term: specific granule membrane
ontology: CC
definition:
The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.


go_id: GO:0035580
term: specific granule lumen
ontology: CC
definition:
The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.


go_id: GO:0035581
term: sequestering of extracellular ligand from receptor
ontology: BP
definition:
The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor.


go_id: GO:0035582
term: sequestering of BMP in extracellular matrix
ontology: BP
definition:
Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.


go_id: GO:0035583
term: sequestering of TGFbeta in extracellular matrix
ontology: BP
definition:
Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins.


go_id: GO:0035584
term: calcium-mediated signaling using intracellular calcium source
ontology: BP
definition:
A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response.


go_id: GO:0035585
term: calcium-mediated signaling using extracellular calcium source
ontology: BP
definition:
A series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response.


go_id: GO:0035586
term: purinergic receptor activity
ontology: MF
definition:
Combining with a purine or purine derivative (purine nucleoside or purine nucleotide) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.


go_id: GO:0035587
term: purinergic receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative to initiate a change in cell activity.


go_id: GO:0035588
term: G-protein coupled purinergic receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.


go_id: GO:0035589
term: G-protein coupled purinergic nucleotide receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.


go_id: GO:0035590
term: purinergic nucleotide receptor signaling pathway
ontology: BP
definition:
The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide to initiate a change in cell activity.


go_id: GO:0035591
term: signaling adaptor activity
ontology: MF
definition:
The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.


go_id: GO:0035593
ontology: BP
term:
positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region

definition:
Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region.


go_id: GO:0035594
term: ganglioside binding
ontology: MF
definition:
Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.


go_id: GO:0035595
term: N-acetylglucosaminylinositol deacetylase activity
ontology: MF
definition:
Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol.


go_id: GO:0035597
term: N6-isopentenyladenosine methylthiotransferase activity
ontology: MF
definition:
Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A).


go_id: GO:0035598
term: N6-threonylcarbomyladenosine methylthiotransferase activity
ontology: MF
definition:
Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A).


go_id: GO:0035599
term: aspartic acid methylthiotransferase activity
ontology: MF
definition:
Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid.


go_id: GO:0035601
term: protein deacylation
ontology: BP
definition:
The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.


go_id: GO:0035602
ontology: BP
term:
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow

definition:
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.


go_id: GO:0035603
term: fibroblast growth factor receptor signaling pathway involved in hemopoiesis
ontology: BP
definition:
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis.


go_id: GO:0035604
ontology: BP
term:
fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow

definition:
The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.


go_id: GO:0035605
term: peptidyl-cysteine S-nitrosylase activity
ontology: MF
definition:
Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein.


go_id: GO:0035607
term: fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
ontology: BP
definition:
The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state.


go_id: GO:0035608
term: protein deglutamylation
ontology: BP
definition:
The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation.


go_id: GO:0035610
term: protein side chain deglutamylation
ontology: BP
definition:
The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.


go_id: GO:0035611
term: protein branching point deglutamylation
ontology: BP
definition:
The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue.


go_id: GO:0035612
term: AP-2 adaptor complex binding
ontology: MF
definition:
Interacting selectively and non-covalently with the AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).


go_id: GO:0035613
term: RNA stem-loop binding
ontology: MF
definition:
Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.


go_id: GO:0035614
term: snRNA stem-loop binding
ontology: MF
definition:
Interacting selectively and non-covalently with a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.


go_id: GO:0035615
term: clathrin adaptor activity
ontology: MF
definition:
The binding activity of a molecule that brings together clathrin and one or more other molecules, permitting them to function in a coordinated way.


go_id: GO:0035616
term: histone H2B conserved C-terminal lysine deubiquitination
ontology: BP
definition:
A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.


go_id: GO:0035618
term: root hair
ontology: CC
definition:
A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall.


go_id: GO:0035620
term: ceramide transporter activity
ontology: MF
definition:
Enables the directed movement of ceramides into, out of or within a cell, or between cells. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.


go_id: GO:0035621
term: ER to Golgi ceramide transport
ontology: BP
definition:
The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.


go_id: GO:0035622
term: intrahepatic bile duct development
ontology: BP
definition:
The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).


go_id: GO:0035623
term: renal glucose absorption
ontology: BP
definition:
A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.


go_id: GO:0035624
term: receptor transactivation
ontology: BP
definition:
The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer.


go_id: GO:0035625
ontology: BP
term:
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway

definition:
The process in which an epidermal growth factor-activated receptor is activated via signaling events from a G-protein coupled receptor. This is an example of cross-talk between the EGF and GPCR signaling pathways.


go_id: GO:0035626
term: juvenile hormone mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of juvenile hormone to a receptor, and ending with regulation of cell state or activity.


go_id: GO:0035627
term: ceramide transport
ontology: BP
definition:
The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.


go_id: GO:0035628
term: cystic duct development
ontology: BP
definition:
The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gall bladder to the common bile duct.


go_id: GO:0035630
term: bone mineralization involved in bone maturation
ontology: BP
definition:
The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state.


go_id: GO:0035631
term: CD40 receptor complex
ontology: CC
definition:
A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules.


go_id: GO:0035632
term: mitochondrial prohibitin complex
ontology: CC
definition:
A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.


go_id: GO:0035633
term: maintenance of blood-brain barrier
ontology: BP
definition:
Preserving the permeability barrier between the blood and the brain in a stable functional or structural state. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.


go_id: GO:0035634
term: response to stilbenoid
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.


go_id: GO:0035635
term: entry of bacterium into host cell
ontology: BP
definition:
The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0035638
term: signal maturation
ontology: BP
definition:
Any process leading to the attainment of the full functional capacity of a signal. A signal is a physical entity or change in state that is used to transfer information to trigger a response, and is functional when it can activate a receptor.


go_id: GO:0035639
term: purine ribonucleoside triphosphate binding
ontology: MF
definition:
Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.


go_id: GO:0035642
term: histone methyltransferase activity (H3-R17 specific)
ontology: MF
definition:
Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to arginine at position 17 of histone H3.


go_id: GO:0035643
term: L-DOPA receptor activity
ontology: MF
definition:
Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine.


go_id: GO:0035645
term: enteric smooth muscle cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.


go_id: GO:0035646
term: endosome to melanosome transport
ontology: BP
definition:
The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle.


go_id: GO:0035647
term: 3-oxo-delta(4,5)-steroid 5-beta-reductase activity
ontology: MF
definition:
Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H(+) = a 5-beta-3-oxo-steroid + NADP(+).


go_id: GO:0035649
term: Nrd1 complex
ontology: CC
definition:
A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p.


go_id: GO:0035650
term: AP-1 adaptor complex binding
ontology: MF
definition:
Interacting selectively and non-covalently with the AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).


go_id: GO:0035651
term: AP-3 adaptor complex binding
ontology: MF
definition:
Interacting selectively and non-covalently with the AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).


go_id: GO:0035652
term: cargo loading into clathrin-coated vesicle
ontology: BP
definition:
Formation of a protein complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins that are going to be transported by a vesicle.


go_id: GO:0035653
term: cargo loading into clathrin-coated vesicle, AP-1-mediated
ontology: BP
definition:
Formation of a protein complex between proteins of the AP-1 adaptor complex and proteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking.


go_id: GO:0035654
term: cargo loading into clathrin-coated vesicle, AP-3-mediated
ontology: BP
definition:
Formation of a protein complex between proteins of the AP-3 adaptor complex and proteins that are going to be transported by a clathrin-coated vesicle. In some cases, The AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle.


go_id: GO:0035655
term: interleukin-18-mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035656
term: kinesin-associated melanosomal adaptor activity
ontology: MF
definition:
The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to melanosomes.


go_id: GO:0035657
term: eRF1 methyltransferase complex
ontology: CC
definition:
A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.


go_id: GO:0035658
term: Mon1-Ccz1 complex
ontology: CC
definition:
A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p.


go_id: GO:0035659
term: Wnt signaling pathway involved in wound healing, spreading of epidermal cells
ontology: BP
definition:
The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis that contributes to the migration of an epidermal cell along or through a wound gap to reestablish a continuous epidermis.


go_id: GO:0035660
term: MyD88-dependent toll-like receptor 4 signaling pathway
ontology: BP
definition:
Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.


go_id: GO:0035661
term: MyD88-dependent toll-like receptor 2 signaling pathway
ontology: BP
definition:
Any series of molecular signals generated as a consequence of binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response.


go_id: GO:0035662
term: Toll-like receptor 4 binding
ontology: MF
definition:
Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.


go_id: GO:0035663
term: Toll-like receptor 2 binding
ontology: MF
definition:
Interacting selectively and non-covalently with a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.


go_id: GO:0035664
term: TIRAP-dependent toll-like receptor signaling pathway
ontology: BP
definition:
Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.


go_id: GO:0035665
term: TIRAP-dependent toll-like receptor 4 signaling pathway
ontology: BP
definition:
Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.


go_id: GO:0035666
term: TRIF-dependent toll-like receptor signaling pathway
ontology: BP
definition:
Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.


go_id: GO:0035667
term: TRIF-dependent toll-like receptor 4 signaling pathway
ontology: BP
definition:
Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.


go_id: GO:0035668
term: TRAM-dependent toll-like receptor signaling pathway
ontology: BP
definition:
Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.


go_id: GO:0035669
term: TRAM-dependent toll-like receptor 4 signaling pathway
ontology: BP
definition:
Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.


go_id: GO:0035670
term: plant-type ovary development
ontology: BP
definition:
The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.


go_id: GO:0035672
term: oligopeptide transmembrane transport
ontology: BP
definition:
The directed movement of an oligopeptide across a membrane by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.


go_id: GO:0035674
term: tricarboxylic acid transmembrane transport
ontology: BP
definition:
The process in which tricarboxylic acids are transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0035675
term: neuromast hair cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.


go_id: GO:0035676
term: anterior lateral line neuromast hair cell development
ontology: BP
definition:
The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.


go_id: GO:0035677
term: posterior lateral line neuromast hair cell development
ontology: BP
definition:
The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.


go_id: GO:0035678
term: neuromast hair cell morphogenesis
ontology: BP
definition:
The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.


go_id: GO:0035679
term: anterior lateral line neuromast hair cell morphogenesis
ontology: BP
definition:
The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.


go_id: GO:0035680
term: posterior lateral line neuromast hair cell morphogenesis
ontology: BP
definition:
The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.


go_id: GO:0035683
term: memory T cell extravasation
ontology: BP
definition:
The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive.


go_id: GO:0035684
term: helper T cell extravasation
ontology: BP
definition:
The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.


go_id: GO:0035685
term: helper T cell diapedesis
ontology: BP
definition:
The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.


go_id: GO:0035686
term: sperm fibrous sheath
ontology: CC
definition:
A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat.


go_id: GO:0035687
term: T-helper 1 cell extravasation
ontology: BP
definition:
The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.


go_id: GO:0035688
term: T-helper 1 cell diapedesis
ontology: BP
definition:
The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.


go_id: GO:0035689
term: chemokine (C-C motif) ligand 5 signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of the chemokine CCL5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035690
term: cellular response to drug
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.


go_id: GO:0035691
term: macrophage migration inhibitory factor signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of macrophage migration inhibitory factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035692
term: macrophage migration inhibitory factor receptor complex
ontology: CC
definition:
A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins.


go_id: GO:0035693
term: NOS2-CD74 complex
ontology: CC
definition:
A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases.


go_id: GO:0035694
term: mitochondrial protein catabolic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.


go_id: GO:0035695
term: mitophagy by induced vacuole formation
ontology: BP
definition:
The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.


go_id: GO:0035697
term: CD8-positive, alpha-beta T cell extravasation
ontology: BP
definition:
The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue.


go_id: GO:0035698
term: CD8-positive, alpha-beta cytotoxic T cell extravasation
ontology: BP
definition:
The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue.


go_id: GO:0035700
term: astrocyte chemotaxis
ontology: BP
definition:
The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


go_id: GO:0035701
term: hematopoietic stem cell migration
ontology: BP
definition:
The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.


go_id: GO:0035702
term: monocyte homeostasis
ontology: BP
definition:
The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.


go_id: GO:0035708
term: interleukin-4-dependent isotype switching to IgE isotypes
ontology: BP
definition:
The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4).


go_id: GO:0035709
term: memory T cell activation
ontology: BP
definition:
The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


go_id: GO:0035710
term: CD4-positive, alpha-beta T cell activation
ontology: BP
definition:
The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


go_id: GO:0035711
term: T-helper 1 cell activation
ontology: BP
definition:
The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


go_id: GO:0035712
term: T-helper 2 cell activation
ontology: BP
definition:
The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


go_id: GO:0035713
term: response to nitrogen dioxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.


go_id: GO:0035714
term: cellular response to nitrogen dioxide
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.


go_id: GO:0035718
term: macrophage migration inhibitory factor binding
ontology: MF
definition:
Interacting selectively and non-covalently with the cytokine, macrophage migration inhibitory factor.


go_id: GO:0035720
term: intraciliary anterograde transport
ontology: BP
definition:
The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.


go_id: GO:0035721
term: intraciliary retrograde transport
ontology: BP
definition:
The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.


go_id: GO:0035722
term: interleukin-12-mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035723
term: interleukin-15-mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035724
term: CD24 biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation.


go_id: GO:0035725
term: sodium ion transmembrane transport
ontology: BP
definition:
A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.


go_id: GO:0035726
term: common myeloid progenitor cell proliferation
ontology: BP
definition:
The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage.


go_id: GO:0035727
term: lysophosphatidic acid binding
ontology: MF
definition:
Interacting selectively and non-covalently with lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G-protein-coupled receptors.


go_id: GO:0035728
term: response to hepatocyte growth factor
ontology: BP
definition:
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.


go_id: GO:0035729
term: cellular response to hepatocyte growth factor stimulus
ontology: BP
definition:
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.


go_id: GO:0035730
term: S-nitrosoglutathione binding
ontology: MF
definition:
Interacting selectively and non-covalently with S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems.


go_id: GO:0035731
term: dinitrosyl-iron complex binding
ontology: MF
definition:
Interacting selectively and non-covalently with a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO.


go_id: GO:0035732
term: nitric oxide storage
ontology: BP
definition:
The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins.


go_id: GO:0035733
term: hepatic stellate cell activation
ontology: BP
definition:
A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.


go_id: GO:0035735
term: intraciliary transport involved in cilium morphogenesis
ontology: BP
definition:
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium morphogenesis.


go_id: GO:0035736
term: cell proliferation involved in compound eye morphogenesis
ontology: BP
definition:
The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis.


go_id: GO:0035737
term: injection of substance in to other organism
ontology: BP
definition:
The process of forcing a substance into another organism, either by penetrating the skin of the other organism or by applying the substance externally to a sensitive tissue such as those that surround the eyes.


go_id: GO:0035738
term: envenomation resulting in modification of morphology or physiology of other organism
ontology: BP
definition:
The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism.


go_id: GO:0035746
term: granzyme A production
ontology: BP
definition:
The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


go_id: GO:0035747
term: natural killer cell chemotaxis
ontology: BP
definition:
The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


go_id: GO:0035750
term: protein localization to myelin sheath abaxonal region
ontology: BP
definition:
Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon.


go_id: GO:0035751
term: regulation of lysosomal lumen pH
ontology: BP
definition:
Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


go_id: GO:0035752
term: lysosomal lumen pH elevation
ontology: BP
definition:
Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.


go_id: GO:0035753
term: maintenance of DNA trinucleotide repeats
ontology: BP
definition:
Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs.


go_id: GO:0035754
term: B cell chemotaxis
ontology: BP
definition:
The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


go_id: GO:0035755
term: cardiolipin hydrolase activity
ontology: MF
definition:
Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol) to form phosphatidic acid (PA).


go_id: GO:0035756
term: transepithelial migration of symbiont in host
ontology: BP
definition:
The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


go_id: GO:0035759
term: mesangial cell-matrix adhesion
ontology: BP
definition:
The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney.


go_id: GO:0035760
term: cytoplasmic polyadenylation-dependent rRNA catabolic process
ontology: BP
definition:
The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.


go_id: GO:0035761
term: dorsal motor nucleus of vagus nerve maturation
ontology: BP
definition:
A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state.


go_id: GO:0035762
term: dorsal motor nucleus of vagus nerve morphogenesis
ontology: BP
definition:
The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form.


go_id: GO:0035763
term: dorsal motor nucleus of vagus nerve structural organization
ontology: BP
definition:
The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure.


go_id: GO:0035764
term: dorsal motor nucleus of vagus nerve formation
ontology: BP
definition:
The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts.


go_id: GO:0035765
term: motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation
ontology: BP
definition:
The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve.


go_id: GO:0035766
term: cell chemotaxis to fibroblast growth factor
ontology: BP
definition:
The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF).


go_id: GO:0035767
term: endothelial cell chemotaxis
ontology: BP
definition:
The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


go_id: GO:0035768
term: endothelial cell chemotaxis to fibroblast growth factor
ontology: BP
definition:
The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF).


go_id: GO:0035770
term: ribonucleoprotein granule
ontology: CC
definition:
A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.


go_id: GO:0035771
term: interleukin-4-mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of interleukin-4 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035772
term: interleukin-13-mediated signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of interleukin-13 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035773
term: insulin secretion involved in cellular response to glucose stimulus
ontology: BP
definition:
The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.


go_id: GO:0035774
term: positive regulation of insulin secretion involved in cellular response to glucose stimulus
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.


go_id: GO:0035775
term: pronephric glomerulus morphogenesis
ontology: BP
definition:
The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.


go_id: GO:0035776
term: pronephric proximal tubule development
ontology: BP
definition:
The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.


go_id: GO:0035777
term: pronephric distal tubule development
ontology: BP
definition:
The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.


go_id: GO:0035778
term: pronephric nephron tubule epithelial cell differentiation
ontology: BP
definition:
The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state.


go_id: GO:0035779
term: angioblast cell differentiation
ontology: BP
definition:
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).


go_id: GO:0035780
term: CD80 biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival.


go_id: GO:0035781
term: CD86 biosynthetic process
ontology: BP
definition:
The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.


go_id: GO:0035782
term: mature natural killer cell chemotaxis
ontology: BP
definition:
The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.


go_id: GO:0035783
term: CD4-positive, alpha-beta T cell costimulation
ontology: BP
definition:
The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.


go_id: GO:0035784
term: nickel cation homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of nickel cations within an organism or cell.


go_id: GO:0035785
term: cellular nickel ion homeostasis
ontology: BP
definition:
Any process involved in the maintenance of an internal steady state of nickel ions at the level of a cell.


go_id: GO:0035786
term: protein complex oligomerization
ontology: BP
definition:
The association of two or more multisubunit protein complexes to form dimers or other multimers of a protein complex.


go_id: GO:0035787
term: cell migration involved in kidney development
ontology: BP
definition:
The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.


go_id: GO:0035788
term: cell migration involved in metanephros development
ontology: BP
definition:
The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ.


go_id: GO:0035789
term: metanephric mesenchymal cell migration
ontology: BP
definition:
The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros.


go_id: GO:0035790
term: platelet-derived growth factor receptor-alpha signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035791
term: platelet-derived growth factor receptor-beta signaling pathway
ontology: BP
definition:
A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.


go_id: GO:0035792
term: other organism postsynaptic membrane
ontology: CC
definition:
A postsynaptic membrane that is part of another organism, i.e. a secondary organism with which the first organism is interacting. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane.


go_id: GO:0035793
ontology: BP
term:
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway

definition:
Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands.


go_id: GO:0035794
term: positive regulation of mitochondrial membrane permeability
ontology: BP
definition:
Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.


go_id: GO:0035795
term: negative regulation of mitochondrial membrane permeability
ontology: BP
definition:
Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.


go_id: GO:0035796
term: ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing
ontology: CC
definition:
A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP.


