Index of /cvmfsmonitor/repository/facilities.gridpp.ac.uk/ccp4/release-7.0-updated/ccp4-7.0/share/ccp4i2/demo_data/CDK1CyclinBCKS2
Demo data: CDK1CyclinBCKS2
CCP4i2 demo data: Inhibitor-bound ternary complex of CDK1, Cyclin B1 and CKS2
A ternary complex of CDK1 bound to Cyclin B1 and CKS2, bound to a pyrazole inhibitor
Data files
- 1hck.pdbChain A is monomeric CDK2, i.e. inactive conformation
- 1jst.pdbChain A is CDK2 in complex with Cyclin A, i.e. in active conformation
- 1buh.pdbCKS1 in complex with CDK2
- 2b9r.pdbChains are all human cyclin B1
- CDK1CyclinBCKS2Compound23.mtz
- P06493.fastaSequence of human CDK2: crystallised species had an N-terminal GPLGS proteolysis artefact
- P14635.fastaSequence of human Cyclin B1: crystallised species was untagged residues 175-432
- P33552.fastaSequence of human CKS2: crystallised species added a C-terminal hexahistidine tag
The ligand for this structure looks as follows:
Last modified: Thu Feb 26 14:37:05 GMT 2015